{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T11:03:21Z","timestamp":1782817401623,"version":"3.54.5"},"reference-count":35,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2010,4,2]],"date-time":"2010-04-02T00:00:00Z","timestamp":1270166400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0010018","type":"journal-article","created":{"date-parts":[[2010,4,2]],"date-time":"2010-04-02T21:35:07Z","timestamp":1270244107000},"page":"e10018","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":26,"title":["The Genes Coding for the Conversion of Carbazole to Catechol Are Flanked by IS6100 Elements in Sphingomonas sp. Strain XLDN2-5"],"prefix":"10.1371","volume":"5","author":[{"given":"Zhonghui","family":"Gai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaorui","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cui","family":"Tai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongzhi","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaofei","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geng","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zixin","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2010,4,2]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/S0027-5107(01)00303-7","article-title":"Mutagenic profiles of carbazole in the male germ cells of Swiss albino mice.","volume":"500","author":"AM Jha","year":"2002","journal-title":"Mutat Res"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"2832","DOI":"10.1128\/AEM.02704-06","article-title":"Cometabolic degradation of dibenzofuran and dibenzothiophene by a newly isolated carbazole-degrading <italic>Sphingomonas<\/italic> sp. strain.","volume":"73","author":"Z Gai","year":"2007","journal-title":"Appl Environ Microbiol"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/S0006-291X(02)02183-6","article-title":"Isolation and characterization of <italic>Sphingomonas<\/italic> sp. GTIN11 capable of carbazole metabolism in petroleum.","volume":"297","author":"JJ Kilbane 2nd","year":"2002","journal-title":"Biochem Biophys Res Commun"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"1563","DOI":"10.1271\/bbb.63.1563","article-title":"Selective and continuous degradation of carbazole contained in petroleum oil by resting cells of <italic>Sphingomonas<\/italic> sp. CDH-7.","volume":"63","author":"K Kirimura","year":"1999","journal-title":"Biosci Biotechnol Biochem"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1007\/s00253-006-0530-3","article-title":"Degradation of carbazole and its derivatives by a <italic>Pseudomonas<\/italic> sp.","volume":"73","author":"L Li","year":"2006","journal-title":"Appl Microbiol Biotechnol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"3663","DOI":"10.1128\/JB.183.12.3663-3679.2001","article-title":"Genetic characterization and evolutionary implications of a car gene cluster in the carbazole degrader <italic>Pseudomonas<\/italic> sp. strain CA10.","volume":"183","author":"H Nojiri","year":"2001","journal-title":"J Bacteriol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"57","DOI":"10.2323\/jgam.44.57","article-title":"Cloning and nucleotide sequence of carbazole catabolic genes from <italic>Pseudomonas stutzeri<\/italic> strain OM1, isolated from activated sludge.","volume":"44","author":"N Ouchiyama","year":"1998","journal-title":"J Gen Appl Microbiol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1006\/bbrc.1998.8750","article-title":"Novel carbazole degradation genes of <italic>Sphingomonas<\/italic> CB3: sequence analysis, transcription, and molecular ecology.","volume":"247","author":"JM Shepherd","year":"1998","journal-title":"Biochem Biophys Res Commun"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"3105","DOI":"10.1128\/JB.181.10.3105-3113.1999","article-title":"Diverse oxygenations catalyzed by carbazole 1,9a-dioxygenase from <italic>Pseudomonas<\/italic> sp. Strain CA10.","volume":"181","author":"H Nojiri","year":"1999","journal-title":"J Bacteriol"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"3198","DOI":"10.1128\/AEM.72.5.3198-3205.2006","article-title":"Plasmid pCAR3 contains multiple gene sets involved in the conversion of carbazole to anthranilate.","volume":"72","author":"M Urata","year":"2006","journal-title":"Appl Environ Microbiol"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2323\/jgam.49.1","article-title":"The unique aromatic catabolic genes in sphingomonads degrading polycyclic aromatic hydrocarbons (PAHs).","volume":"49","author":"O Pinyakong","year":"2003","journal-title":"J Gen Appl Microbiol"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.1128\/JB.181.5.1585-1602.1999","article-title":"Complete sequence of a 184-kilobase catabolic plasmid from <italic>Sphingomonas aromaticivorans<\/italic> F199.","volume":"181","author":"MF Romine","year":"1999","journal-title":"J Bacteriol"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1128\/MMBR.62.3.725-774.1998","article-title":"Insertion sequences.","volume":"62","author":"J Mahillon","year":"1998","journal-title":"Microbiol Mol Biol Rev"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"2225","DOI":"10.1128\/JB.186.8.2225-2235.2004","article-title":"Organization of lin genes and IS<italic>6100<\/italic> among different strains of hexachlorocyclohexane-degrading <italic>Sphingomonas paucimobilis<\/italic>: evidence for horizontal gene transfer.","volume":"186","author":"C Dogra","year":"2004","journal-title":"J Bacteriol"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1128\/jb.176.4.1197-1200.1994","article-title":"Insertion sequence IS<italic>6100<\/italic> on plasmid pOAD2, which degrades nylon oligomers.","volume":"176","author":"K Kato","year":"1994","journal-title":"J Bacteriol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1038\/345739a0","article-title":"Transposition of an antibiotic resistance element in mycobacteria.","volume":"345","author":"C Martin","year":"1990","journal-title":"Nature"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1046\/j.1432-1327.1998.2530437.x","article-title":"The reductase RedA2 of the multi-component dioxin dioxygenase system of <italic>Sphingomonas<\/italic> sp. RW1 is related to class-I cytochrome P450-type reductases.","volume":"253","author":"J Armengaud","year":"1998","journal-title":"Eur J Biochem"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"24759","DOI":"10.1074\/jbc.M500597200","article-title":"A three-component dicamba O-demethylase from <italic>Pseudomonas maltophilia<\/italic>, strain DI-6: gene isolation, characterization, and heterologous expression.","volume":"280","author":"PL Herman","year":"2005","journal-title":"J Biol Chem"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"6066","DOI":"10.1016\/S0021-9258(19)39292-0","article-title":"Putidaredoxin reductase and putidaredoxin. Cloning, sequence determination, and heterologous expression of the proteins.","volume":"265","author":"JA Peterson","year":"1990","journal-title":"J Biol Chem"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"5871","DOI":"10.1128\/JB.185.19.5871-5881.2003","article-title":"Characterization and regulation of the genes for a novel anthranilate 1,2-dioxygenase from <italic>Burkholderia cepacia<\/italic> DBO1.","volume":"185","author":"HK Chang","year":"2003","journal-title":"J Bacteriol"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"2007","DOI":"10.1128\/JB.01486-06","article-title":"The <italic>Sphingomonas<\/italic> plasmid pCAR3 is involved in complete mineralization of carbazole.","volume":"189","author":"M Shintani","year":"2007","journal-title":"J Bacteriol"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"6286","DOI":"10.1128\/jb.176.20.6286-6294.1994","article-title":"Integrons found in different locations have identical 5\u2032 ends but variable 3\u2032 ends.","volume":"176","author":"RM Hall","year":"1994","journal-title":"J Bacteriol"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"2891","DOI":"10.1128\/AEM.61.8.2891-2897.1995","article-title":"Expression of the <italic>strA-strB<\/italic> streptomycin resistance genes in <italic>Pseudomonas syringae<\/italic> and <italic>Xanthomonas campestris<\/italic> and characterization of IS<italic>6100<\/italic> in <italic>X. campestris<\/italic>.","volume":"61","author":"GW Sundin","year":"1995","journal-title":"Appl Environ Microbiol"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1111\/j.1574-6968.2000.tb09245.x","article-title":"Partial characterization of a genomic island associated with the multidrug resistance region of <italic>Salmonella enterica Typhymurium<\/italic> DT104.","volume":"189","author":"DA Boyd","year":"2000","journal-title":"FEMS Microbiol Lett"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/S0147-619X(02)00120-8","article-title":"The 27.8-kb R-plasmid pTET3 from Corynebacterium glutamicum encodes the aminoglycoside adenyltransferase gene cassette aadA9 and the regulated tetracycline efflux system Tet 33 flanked by active copies of the widespread insertion sequence IS<italic>6100<\/italic>.","volume":"48","author":"A Tauch","year":"2002","journal-title":"Plasmid"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"4850","DOI":"10.1128\/jb.179.15.4850-4858.1997","article-title":"Identification and characterization of genes encoding carbazole 1,9a-dioxygenase in <italic>Pseudomonas<\/italic> sp. strain CA10.","volume":"179","author":"SI Sato","year":"1997","journal-title":"J Bacteriol"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1038\/sj.jim.2900475","article-title":"Aromatic hydrocarbon degradation by <italic>Sphingomonas yanoikuyae<\/italic> B1.","volume":"19","author":"GJ Zylstra","year":"1997","journal-title":"J Ind Microbiol Biotechnol"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"3954","DOI":"10.1128\/JB.180.15.3954-3966.1998","article-title":"Genetic analysis of dioxin dioxygenase of <italic>Sphingomonas<\/italic> sp. strain RW1: catabolic genes dispersed on the genome.","volume":"180","author":"J Armengaud","year":"1998","journal-title":"J Bacteriol"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"4672","DOI":"10.1128\/JB.184.17.4672-4680.2002","article-title":"Organization and regulation of pentachlorophenol-degrading genes in <italic>Sphingobium chlorophenolicum<\/italic> ATCC 39723.","volume":"184","author":"M Cai","year":"2002","journal-title":"J Bacteriol"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1038\/sj.jim.2900736","article-title":"Complete analysis of genes and enzymes for gamma-hexachlorocyclohexane degradation in <italic>Sphingomonas paucimobilis<\/italic> UT26.","volume":"23","author":"Y Nagata","year":"1999","journal-title":"J Ind Microbiol Biotechnol"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"2651","DOI":"10.1128\/AEM.72.4.2651-2660.2006","article-title":"The locus coding for the 3-nitrobenzoate dioxygenase of Comamonas sp. strain JS46 is flanked by IS<italic>1071<\/italic> elements and is subject to deletion and inversion events.","volume":"72","author":"MA Providenti","year":"2006","journal-title":"Appl Environ Microbiol"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"6421","DOI":"10.1128\/AEM.01051-07","article-title":"Degradation of carbazole by microbial cells immobilized in magnetic gellan gum gel beads.","volume":"73","author":"X Wang","year":"2007","journal-title":"Appl Environ Microbiol"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"3804","DOI":"10.1099\/mic.0.2008\/023176-0","article-title":"Microbial transformation of benzothiophenes, with carbazole as the auxiliary substrate, by <italic>Sphingomonas<\/italic> sp. strain XLDN2-5.","volume":"154","author":"Z Gai","year":"2008","journal-title":"Microbiology"},{"key":"ref34","article-title":"Molecular cloning: A laboratory manual.","author":"J Sambrook","year":"2001"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"3497","DOI":"10.1093\/nar\/gkg500","article-title":"Multiple sequence alignment with the Clustal series of programs.","volume":"31","author":"R Chenna","year":"2003","journal-title":"Nucleic Acids Res"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0010018","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,25]],"date-time":"2021-10-25T13:33:16Z","timestamp":1635168796000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0010018"}},"subtitle":[],"editor":[{"given":"Laurent","family":"R\u00e9nia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2010,4,2]]},"references-count":35,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2010,4,2]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0010018","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,4,2]]}}}