{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,1,14]],"date-time":"2024-01-14T22:00:14Z","timestamp":1705269614449},"reference-count":36,"publisher":"Public Library of Science (PLoS)","issue":"7","license":[{"start":{"date-parts":[[2010,7,13]],"date-time":"2010-07-13T00:00:00Z","timestamp":1278979200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0011564","type":"journal-article","created":{"date-parts":[[2010,7,13]],"date-time":"2010-07-13T20:00:10Z","timestamp":1279051210000},"page":"e11564","update-policy":"http:\/\/dx.doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":20,"title":["Study of Transcriptional Effects in Cis at the IFIH1 Locus"],"prefix":"10.1371","volume":"5","author":[{"given":"Hana","family":"Zouk","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luc","family":"Marchand","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Constantin","family":"Polychronakos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2010,7,13]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1038\/ng1800","article-title":"A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region.","volume":"38","author":"DJ Smyth","year":"2006","journal-title":"Nat Genet"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1789","DOI":"10.1038\/sj.onc.1207300","article-title":"Expression analysis and genomic characterization of human melanoma differentiation associated gene-5, mda-5: a novel type I interferon-responsive apoptosis-inducing gene.","volume":"23","author":"DC Kang","year":"2004","journal-title":"Oncogene"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1073\/pnas.022637199","article-title":"mda-5: An interferon-inducible putative RNA helicase with double-stranded RNA-dependent ATPase activity and melanoma growth-suppressive properties.","volume":"99","author":"DC Kang","year":"2002","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"2851","DOI":"10.4049\/jimmunol.175.5.2851","article-title":"Shared and unique functions of the DExD\/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity.","volume":"175","author":"M Yoneyama","year":"2005","journal-title":"J Immunol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1007\/s00125-002-0852-3","article-title":"The role of viruses in human diabetes.","volume":"45","author":"H Hyoty","year":"2002","journal-title":"Diabetologia"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1016\/j.biocel.2005.08.019","article-title":"Enteroviruses: new findings on the role of enteroviruses in type 1 diabetes.","volume":"38","author":"M Roivainen","year":"2006","journal-title":"Int J Biochem Cell Biol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1002\/dmrr.695","article-title":"Viral infections as potential triggers of type 1 diabetes.","volume":"23","author":"N van der Werf","year":"2007","journal-title":"Diabetes Metab Res Rev"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1126\/science.1167728","article-title":"Rare variants of IFIH1, a gene implicated in antiviral responses, protect against type 1 diabetes.","volume":"324","author":"S Nejentsev","year":"2009","journal-title":"Science"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"13348","DOI":"10.1074\/jbc.M809449200","article-title":"Identification of loss of function mutations in human genes encoding RIG-I and MDA5: implications for resistance to type I diabetes.","volume":"284","author":"T Shigemoto","year":"2009","journal-title":"J Biol Chem"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"1696","DOI":"10.1056\/NEJMp0806284","article-title":"Common genetic variation and human traits.","volume":"360","author":"DB Goldstein","year":"2009","journal-title":"N Engl J Med"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"2928","DOI":"10.1016\/S0021-9258(19)50675-5","article-title":"Molecular cloning and characterization of grancalcin, a novel EF-hand calcium-binding protein abundant in neutrophils and monocytes.","volume":"267","author":"A Boyhan","year":"1992","journal-title":"J Biol Chem"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"5566","DOI":"10.1158\/1078-0432.CCR-05-0699","article-title":"Induction of CD4(+) and CD8(+) T-cell responses to the human stromal antigen, fibroblast activation protein: implication for cancer immunotherapy.","volume":"11","author":"M Fassnacht","year":"2005","journal-title":"Clin Cancer Res"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1007\/s00018-007-6478-3","article-title":"Circadian changes of ether-a-go-go-related-gene (Erg) potassium channel transcripts in the rat pancreas and beta-cell.","volume":"64","author":"E Muhlbauer","year":"2007","journal-title":"Cell Mol Life Sci"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1093\/hmg\/ddn342","article-title":"IFIH1 polymorphisms are significantly associated with type 1 diabetes and IFIH1 gene expression in peripheral blood mononuclear cells.","volume":"18","author":"S Liu","year":"2009","journal-title":"Hum Mol Genet"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1038\/ng2109","article-title":"A genome-wide association study of global gene expression.","volume":"39","author":"AL Dixon","year":"2007","journal-title":"Nat Genet"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"R40","DOI":"10.1186\/ar2179","article-title":"The interferon induced with helicase domain 1 A946T polymorphism is not associated with rheumatoid arthritis.","volume":"9","author":"I Marinou","year":"2007","journal-title":"Arthritis Res Ther"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1126\/science.1072545","article-title":"Allelic variation in human gene expression.","volume":"297","author":"H Yan","year":"2002","journal-title":"Science"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1038\/ng0397-289","article-title":"Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM2 locus.","volume":"15","author":"P Vafiadis","year":"1997","journal-title":"Nat Genet"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1038\/sj.gene.6364211","article-title":"Allelic effects on gene regulation at the autoimmunity-predisposing CTLA4 locus: a re-evaluation of the 3\u2032 +6230G&gt;A polymorphism.","volume":"6","author":"SM Anjos","year":"2005","journal-title":"Genes Immun"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1126\/science.1101659","article-title":"Cis-acting regulatory variation in the human genome.","volume":"306","author":"T Pastinen","year":"2004","journal-title":"Science"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1152\/physiolgenomics.00163.2003","article-title":"A survey of genetic and epigenetic variation affecting human gene expression.","volume":"16","author":"T Pastinen","year":"2004","journal-title":"Physiol Genomics"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1101\/gr.1.3.160","article-title":"A sensitive, quantitative assay for measurement of allele-specific transcripts differing by a single nucleotide.","volume":"1","author":"J Singer-Sam","year":"1992","journal-title":"PCR Methods Appl"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1097\/01.ypg.0000218612.35139.84","article-title":"Investigating cis-acting regulatory variation using assays of relative allelic expression.","volume":"16","author":"NJ Bray","year":"2006","journal-title":"Psychiatr Genet"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"R255","DOI":"10.1093\/hmg\/ddh227","article-title":"Allele-specific gene expression differences in humans.","volume":"13 Spec No 2","author":"PR Buckland","year":"2004","journal-title":"Hum Mol Genet"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"10469","DOI":"10.1073\/pnas.89.21.10469","article-title":"Parental imprinting studied by allele-specific primer extension after PCR: paternal X chromosome-linked genes are transcribed prior to preferential paternal X chromosome inactivation.","volume":"89","author":"J Singer-Sam","year":"1992","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"e1000006","DOI":"10.1371\/journal.pgen.1000006","article-title":"Differential allelic expression in the human genome: a robust approach to identify genetic and epigenetic cis-acting mechanisms regulating gene expression.","volume":"4","author":"D Serre","year":"2008","journal-title":"PLoS Genet"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"709","DOI":"10.2337\/db06-0402","article-title":"Evaluation of polymorphic splicing in the mechanism of the association of the insulin gene with diabetes.","volume":"56","author":"L Marchand","year":"2007","journal-title":"Diabetes"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1006\/bbrc.2001.5500","article-title":"Evidence against GRB10 as the gene responsible for Silver-Russell syndrome.","volume":"286","author":"JA McCann","year":"2001","journal-title":"Biochem Biophys Res Commun"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1007\/s004390000397","article-title":"Cheap, accurate and rapid allele frequency estimation of single nucleotide polymorphisms by primer extension and DHPLC in DNA pools.","volume":"107","author":"B Hoogendoorn","year":"2000","journal-title":"Hum Genet"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1007\/s00439-002-0706-6","article-title":"Universal, robust, highly quantitative SNP allele frequency measurement in DNA pools.","volume":"110","author":"N Norton","year":"2002","journal-title":"Hum Genet"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1038\/ng.434","article-title":"Cell-specific protein phenotypes for the autoimmune locus IL2RA using a genotype-selectable human bioresource.","volume":"41","author":"CA Dendrou","year":"2009","journal-title":"Nat Genet"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1007\/s00125-007-0895-6","article-title":"The association between the IFIH1 locus and type 1 diabetes.","volume":"51","author":"HQ Qu","year":"2008","journal-title":"Diabetologia"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1038\/ng2068","article-title":"Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes.","volume":"39","author":"JA Todd","year":"2007","journal-title":"Nat Genet"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1007\/s00439-003-0956-y","article-title":"Cis-acting variation in the expression of a high proportion of genes in human brain.","volume":"113","author":"NJ Bray","year":"2003","journal-title":"Hum Genet"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"3963","DOI":"10.1093\/hmg\/ddi420","article-title":"Mapping common regulatory variants to human haplotypes.","volume":"14","author":"T Pastinen","year":"2005","journal-title":"Hum Mol Genet"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1038\/ng1673","article-title":"Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant.","volume":"37","author":"T Vang","year":"2005","journal-title":"Nat Genet"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0011564","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,31]],"date-time":"2021-10-31T10:21:51Z","timestamp":1635675711000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0011564"}},"subtitle":[],"editor":[{"given":"Adrian","family":"Vella","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2010,7,13]]},"references-count":36,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2010,7,13]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0011564","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,7,13]]}}}