{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T02:32:21Z","timestamp":1782959541713,"version":"3.54.5"},"reference-count":26,"publisher":"Public Library of Science (PLoS)","issue":"7","license":[{"start":{"date-parts":[[2010,7,21]],"date-time":"2010-07-21T00:00:00Z","timestamp":1279670400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0011706","type":"journal-article","created":{"date-parts":[[2010,7,21]],"date-time":"2010-07-21T21:04:37Z","timestamp":1279746277000},"page":"e11706","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":26,"title":["Association of Blood Lead (Pb) and Plasma Homocysteine: A Cross Sectional Survey in Karachi, Pakistan"],"prefix":"10.1371","volume":"5","author":[{"given":"Mohsin","family":"Yakub","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad Perwaiz","family":"Iqbal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2010,7,21]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1388","DOI":"10.1161\/CIRCULATIONAHA.106.628321","article-title":"Blood lead below 0.48 micromol\/L (10 microg\/dL) and mortality among US adults.","volume":"114","author":"A Menke","year":"2006","journal-title":"Circulation"},{"key":"ref2","article-title":"Is the Center for Disease Control's goal to reduce lead below 10\u00b5g\/dL blood in all children younger than 72 months by 2010, good enough?","author":"TF Schrager","year":"2006"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"3196","DOI":"10.1161\/01.CIR.0000130848.18636.B2","article-title":"Lead, cadmium, smoking, and increased risk of peripheral arterial disease.","volume":"109","author":"A Navas-Acien","year":"2004","journal-title":"Circulation"},{"key":"ref4","first-page":"518","article-title":"Hyperhomocysteinemia as a risk factor for ischemic heart disease.","volume":"14","author":"M Aamir","year":"2004","journal-title":"J Coll Physician Surg Pak"},{"key":"ref5","first-page":"282","article-title":"Hyperhomocysteinemia and coronary artery disease in Pakistan.","volume":"56","author":"MP Iqbal","year":"2006","journal-title":"J Pak Med Assoc"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.numecd.2004.05.003","article-title":"Role of vitamins B6, B12 and folic acid on hyperhomocysteinemia in a Pakistani population of patients with acute myocardial infarction.","volume":"15","author":"MP Iqbal","year":"2005","journal-title":"Nutr Metab Cardiovasc Dis"},{"key":"ref7","first-page":"308","article-title":"Folic acid and vitamin B6 deficiencies related hyperhomocysteinemia in apparently healthy Pakistani adults; Is mass micronutrient supplementation indicated in this population.","volume":"19","author":"MP Iqbal","year":"2009","journal-title":"J Coll Physician Surg Pak"},{"key":"ref8","first-page":"410","article-title":"Effect of environmental lead pollution on blood lead levels in traffic police constables in Islamabad, Pakistan.","volume":"55","author":"F Agha","year":"2005","journal-title":"J Pak Med Assoc"},{"key":"ref9","first-page":"769","article-title":"Factors associated with elevated blood lead concentrations in children in Karachi, Pakistan.","volume":"80","author":"MH Rahbar","year":"2002","journal-title":"Bulletin of the World Health Organization"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1289\/ehp.7369","article-title":"Blood lead is a predictor of homocysteine levels in a population-based study of older adults.","volume":"113","author":"JH Schafer","year":"2005","journal-title":"Environ Health Persp"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1136\/oem.2006.030882","article-title":"Association of blood lead and homocysteine levels among lead exposed subjects in Vietnam and Singapore.","volume":"64(10)","author":"SE Chia","year":"2007","journal-title":"Occup Environ Med"},{"key":"ref12","article-title":"Blood lead levels in school children resulting from leaded petrol use and increasing road traffic in Pakistan","author":"MA Khawaja","year":"2002"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1006\/enrs.1997.3756","article-title":"Higher milk intake during pregnancy is associated with lower maternal and umbilical cord lead levels in postpartum women.","volume":"74","author":"M Hernandez-Avila","year":"1997","journal-title":"Environ Res"},{"key":"ref14","first-page":"131","article-title":"Laboratory haematology","author":"I Chanarin","year":"1989"},{"key":"ref15","article-title":"Modern Analytical Methodologies in Fat and Water-Soluble Vitamins","author":"EV Quadros","year":"2000"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1093\/clinchem\/29.4.642","article-title":"Radioenzymatic assay for direct measurement of plasma pyridoxal 5\u2032-phosphate.","volume":"29","author":"VM Camp","year":"1983","journal-title":"Clin Chem"},{"key":"ref17","first-page":"231","article-title":"A simple and sensitive radioenzymatic assay for pyridoxal 5\u2032-phosphate in human plasma.","volume":"35","author":"MP Iqbal","year":"2003","journal-title":"Pakistan J Zool"},{"key":"ref18","first-page":"1072","article-title":"Screening for elevated blood lead levels. American Academy of Pediatrics Committee on Environmental Health. (1998).","volume":"101(6)","journal-title":"Pediatrics"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1002\/ana.10440","article-title":"Homocysteine, white matter hyperintensities, and cognition in healthy elderly people.","volume":"53","author":"C Dufouil","year":"2003","journal-title":"Ann Neurol"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1097\/00001648-200301000-00011","article-title":"The longitudinal association of lead with blood pressure.","volume":"14","author":"BS Glenn","year":"2003","journal-title":"Epidemiology"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1016\/j.envres.2009.03.012","article-title":"Blood levels of lead, cadmium, and mercury in the Korean population: results from the Second Korean National Human Exposure and Bio-monitoring Examination.","volume":"109","author":"JY Son","year":"2009","journal-title":"Environ Res"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1093\/aje\/152.9.829","article-title":"Patterns and determinants of blood lead during pregnancy.","volume":"152","author":"I Hertz-Picciotto","year":"2000","journal-title":"Am J Epidemiol"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"2188","DOI":"10.1093\/jn\/133.7.2188","article-title":"A mixed fruit and vegetable concentrate increases plasma antioxidant vitamins and folate and lowers plasma homocysteine in men.","volume":"133","author":"S Samman","year":"2003","journal-title":"J Nutr"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"2289","DOI":"10.1001\/jama.281.24.2289","article-title":"Relationship of ascorbic acid to blood lead levels.","volume":"281","author":"JA Simon","year":"1999","journal-title":"JAMA"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1007\/s12033-007-0045-x","article-title":"Role of ascorbic acid in scavenging free radicals and lead toxicity from biosystems.","volume":"37","author":"SA Tariq","year":"2007","journal-title":"Mol Biotechnol"},{"key":"ref26","first-page":"319","article-title":"Blood lead and plasma homocysteine in petrol pump workers in Karachi: Role of vitamins B6, B12, folate and C.","volume":"31","author":"M Yakub","year":"2009","journal-title":"J Chem Soc Pak"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0011706","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,6,7]],"date-time":"2020-06-07T09:09:29Z","timestamp":1591520969000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0011706"}},"subtitle":[],"editor":[{"given":"Alejandro","family":"Lucia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2010,7,21]]},"references-count":26,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2010,7,21]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0011706","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,7,21]]}}}