{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T20:40:35Z","timestamp":1790628035524,"version":"4.1.0"},"reference-count":17,"publisher":"Public Library of Science (PLoS)","issue":"7","license":[{"start":{"date-parts":[[2010,7,29]],"date-time":"2010-07-29T00:00:00Z","timestamp":1280361600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0011841","type":"journal-article","created":{"date-parts":[[2010,7,29]],"date-time":"2010-07-29T22:33:15Z","timestamp":1280442795000},"page":"e11841","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":106,"title":["Methicillin Resistance Transfer from Staphylocccus epidermidis to Methicillin-Susceptible Staphylococcus aureus in a Patient during Antibiotic Therapy"],"prefix":"10.1371","volume":"5","author":[{"given":"Alexander L. A.","family":"Bloemendaal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellen C.","family":"Brouwer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ad C.","family":"Fluit","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2010,7,29]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1128\/AAC.44.6.1549-1555.2000","article-title":"A new class of genetic element, Staphylococcus Cassette Chromosome <italic>mec<\/italic>, encodes methicillin resistance in <italic>Staphylococcus aureus<\/italic>.","volume":"44","author":"Y Katayama","year":"2000","journal-title":"Antimicrob Agents Chemother"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"4961","DOI":"10.1128\/AAC.00579-09","article-title":"Classification of staphylococcal cassette chromosome <italic>mec<\/italic> (SCC<italic>mec<\/italic>): Guidelines for reporting novel SCC<italic>mec<\/italic> elements.","volume":"53","year":"2009","journal-title":"Antimicrob Agents Chemother"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1086\/341078","article-title":"Evidence of extensive interspecies transfer of integron-mediated antimicrobial resistance genes among multidrug-resistant Enterobacteriaceae in a clinical setting.","volume":"186","author":"MA Leverstein-van Hall","year":"2002","journal-title":"J Infect Dis"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1111\/j.1469-0691.2008.02090.x","article-title":"The origin of a methicillin-resistant <italic>Staphylococcus aureus<\/italic> isolate at a neonatal ward in Sweden-possible horizontal transfer of a staphylococcal cassette chromosome <italic>mec<\/italic> between methicillin-resistant <italic>Staphylococcus haemolyticus<\/italic> and <italic>Staphylococcus aureus<\/italic>.","volume":"14","author":"C Berglund","year":"2008","journal-title":"Clin Microbiol Infect"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"1674","DOI":"10.1016\/S0140-6736(00)04832-7","article-title":"<italic>In-vivo<\/italic> transfer of <italic>mecA<\/italic> DNA to <italic>Staphylococcus aureus<\/italic> corrected].","volume":"357","author":"CL Wielders","year":"2001","journal-title":"Lancet"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1128\/AAC.45.5.1323-1336.2001","article-title":"Structural comparison of three types of staphylococcal cassette chromosome <italic>mec<\/italic> integrated in the chromosome in methicillin-resistant <italic>Staphylococcus aureus<\/italic>.","volume":"45","author":"T Ito","year":"2001","journal-title":"Antimicrob Agents Chemother"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"2072","DOI":"10.1128\/AAC.01539-05","article-title":"Novel mobile variants of staphylococcal cassette chromosome <italic>mec<\/italic> in <italic>Staphylococcus aureus<\/italic>.","volume":"50","author":"WT Jansen","year":"2006","journal-title":"Antimicrob Agents Chemother"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"5578","DOI":"10.1128\/JB.00418-06","article-title":"<italic>Sau<\/italic>1: a novel lineage-specific type I restriction-modification system that blocks horizontal gene transfer into <italic>Staphylococcus aureus<\/italic> and between <italic>S. aureus<\/italic> isolates of different lineages.","volume":"188","author":"DE Waldron","year":"2006","journal-title":"J Bacteriol"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"14130","DOI":"10.1073\/pnas.0804178105","article-title":"Frequent emergence and limited geographic dispersal of methicillin-resistant <italic>Staphylococcus aureus<\/italic>.","volume":"105","author":"U N\u00fcbel","year":"2008","journal-title":"Proc Natl Acad Sci USA"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"3926","DOI":"10.1128\/AAC.47.12.3926-3934.2003","article-title":"Evolutionary models of the emergence of methicillin-resistant <italic>Staphylococcus aureus<\/italic>.","volume":"47","author":"DA Robinson","year":"2003","journal-title":"Antimicrob Agents Chemother"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/S1473-3099(09)70066-0","article-title":"Gram-positive toxic shock syndromes.","volume":"9","author":"E Lappin","year":"2009","journal-title":"Lancet Infect Dis"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.jdermsci.2007.05.007","article-title":"Staphylococcal exfoliative toxins: \u201cmolecular scissors\u201d of bacteria that attack the cutaneous defense barrier in mammals.","volume":"49","author":"K Nishifuji","year":"2008","journal-title":"J Dermatol Sci"},{"key":"ref13","doi-asserted-by":"crossref","first-page":":e1000304","DOI":"10.1371\/journal.pgen.1000304","article-title":"The population genetics of dN\/dS.","author":"S Kryazhimskiy","year":"2008","journal-title":"PLoS Genet"},{"key":"ref14","article-title":"Operon structure of <italic>Staphylococcus aureus<\/italic>.","author":"NJ Ten Broeke-Smits","year":"2010","journal-title":"Nucl Acids Res 2010"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"7719","DOI":"10.1128\/jb.176.24.7719-7726.1994","article-title":"Genetic and biochemical analyses of the biosynthesis of the yellow carotenoid 4,4\u2032-diaponeurosporene of <italic>Staphylococcus aureus<\/italic>.","volume":"176","author":"B Wieland","year":"1994","journal-title":"J Bacteriol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1126\/science.1153018","article-title":"A cholesterol biosynthesis inhibitor blocks <italic>Staphylococcus aureus<\/italic> virulence.","volume":"319","author":"CI Liu","year":"2008","journal-title":"Science"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1111\/j.1365-2958.2006.05172.x","article-title":"Sex and virulence in <italic>Escherichia coli<\/italic>: an evolutionary perspective.","volume":"60","author":"T Wirth","year":"2006","journal-title":"Mol Microbiol"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0011841","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,10,23]],"date-time":"2018-10-23T22:23:24Z","timestamp":1540333404000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0011841"}},"subtitle":[],"editor":[{"given":"Frank R.","family":"DeLeo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2010,7,29]]},"references-count":17,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2010,7,29]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0011841","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,7,29]]}}}