{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T14:20:44Z","timestamp":1791037244942,"version":"4.1.0"},"reference-count":40,"publisher":"Public Library of Science (PLoS)","issue":"3","license":[{"start":{"date-parts":[[2011,3,17]],"date-time":"2011-03-17T00:00:00Z","timestamp":1300320000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0017980","type":"journal-article","created":{"date-parts":[[2011,3,17]],"date-time":"2011-03-17T16:57:52Z","timestamp":1300381072000},"page":"e17980","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":90,"title":["Humoral Response to the Anopheles gambiae Salivary Protein gSG6: A Serological Indicator of Exposure to Afrotropical Malaria Vectors"],"prefix":"10.1371","volume":"6","author":[{"given":"Cinzia","family":"Rizzo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raffaele","family":"Ronca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriella","family":"Fiorentino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federica","family":"Verra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentina","family":"Mangano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Poinsignon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sodiomon Bienvenu","family":"Sirima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Issa","family":"N\u00e8bi\u00e8","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabrizio","family":"Lombardo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franck","family":"Remoue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Coluzzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincenzo","family":"Petrarca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Modiano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Arc\u00e0","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2011,3,17]]},"reference":[{"key":"ref1","first-page":"143","article-title":"Blood-feeding arthropods: live syringes or invertebrate pharmacologists?","volume":"4","author":"JMC Ribeiro","year":"1995","journal-title":"Infect Agents Dis"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1146\/annurev.ento.48.060402.102812","article-title":"Role of arthropod saliva in blood feeding: sialome and post-sialome perspectives.","volume":"48","author":"JMC Ribeiro","year":"2003","journal-title":"Annu Rev Entomol"},{"key":"ref3","first-page":"59","article-title":"From Sialomes to the Sialoverse: An Insight into Salivary Potion of Blood-Feeding Insects.","author":"JMC Ribeiro","year":"2009"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1093\/oxfordjournals.aje.a115643","article-title":"Anti-tick antibodies: an epidemiologic tool in Lyme disease research.","volume":"132","author":"BS Schwartz","year":"1990","journal-title":"Am J Epidemiol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"740","DOI":"10.4269\/ajtmh.2000.62.740","article-title":"Human immune response to sand fly salivary gland antigens: a useful epidemiological marker?","volume":"62","author":"A Barral","year":"2000","journal-title":"Am J Trop Med Hyg"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"219","DOI":"10.4269\/ajtmh.2001.65.219","article-title":"Human IgG1 and IgG4: the main antibodies against Triatoma infestans (Hemiptera: Reduviidae) salivary gland proteins.","volume":"65","author":"RJ Nascimento","year":"2001","journal-title":"Am J Trop Med Hyg"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1016\/j.ijpara.2006.05.002","article-title":"Tsetse fly saliva biases the immune response to Th2 and induces anti-vector antibodies that are a useful tool for exposure assessment.","volume":"36","author":"G Caljon","year":"2006","journal-title":"Int J Parasitol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"750","DOI":"10.4269\/ajtmh.2008.78.750","article-title":"Human IgG antibody response to Glossina saliva: an epidemiologic marker of exposure to Glossina bites.","volume":"78","author":"A Poinsignon","year":"2008","journal-title":"Am J Trop Med Hyg"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"481","DOI":"10.4269\/ajtmh.2005.72.481","article-title":"Antibody response to Culex tarsalis salivary gland antigens among sentinel chickens in California.","volume":"72","author":"RT Trevejo","year":"2005","journal-title":"Am J Trop Med Hyg"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.trstmh.2005.06.032","article-title":"Evaluation of the antibody response to Anopheles salivary antigens as a potential marker of risk of malaria.","volume":"100","author":"F Remoue","year":"2006","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.actatropica.2006.02.004","article-title":"Natural human humoral response to salivary gland proteins of Anopheles mosquitoes in Thailand.","volume":"98","author":"A Waitayakul","year":"2006","journal-title":"Acta Trop"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"1454","DOI":"10.1016\/j.micinf.2007.07.012","article-title":"Antibody response against saliva antigens of Anopheles gambiae and Aedes aegypti in travellers in tropical Africa.","volume":"9","author":"E Orlandi-Pradines","year":"2007","journal-title":"Microbes Infect"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1186\/1475-2875-8-121","article-title":"Anti-Anopheles darlingi saliva antibodies as marker of Plasmodium vivax infection and clinical immunity in the Brazilian Amazon.","volume":"8","author":"BB Andrade","year":"2009","journal-title":"Malar J"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.ibmb.2006.10.007","article-title":"An insight into the sialome of the adult female mosquito Aedes albopictus.","volume":"37","author":"B Arc\u00e0","year":"2007","journal-title":"Insect Biochem Mol Biol"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1186\/1471-2164-10-57","article-title":"The salivary gland transcriptome of the neotropical malaria vector Anopheles darlingi reveals accelerated evolution of genes relevant to hematophagy.","volume":"10","author":"E Calvo","year":"2009","journal-title":"BMC Genomics"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1016\/S0965-1748(03)00067-5","article-title":"Exploring the salivary gland transcriptome and proteome of the Anopheles stephensi mosquito.","volume":"33","author":"JG Valenzuela","year":"2003","journal-title":"Insect Biochem Mol Biol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.ibmb.2006.11.005","article-title":"An insight into the sialome of Anopheles funestus reveals an emerging pattern in anopheline salivary protein families.","volume":"37","author":"E Calvo","year":"2007","journal-title":"Insect Biochem Mol Biol"},{"key":"ref18","first-page":"573","article-title":"At the interface between parasite and host: the salivary glands of the African malaria vector Anopheles gambiae.","volume":"48","author":"F Lombardo","year":"2006","journal-title":"Parassitologia"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1016\/j.ibmb.2010.08.002","article-title":"An insight into the sialome of blood-feeding Nematocera.","volume":"40","author":"JM Ribeiro","year":"2010","journal-title":"Insect Biochem Mol Biol"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/S0014-5793(02)02578-4","article-title":"Novel cDNAs encoding salivary proteins from the malaria vector <italic>Anopheles gambiae<\/italic>.","volume":"517","author":"A Lanfrancotti","year":"2002","journal-title":"FEBS Lett"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/j.ibmb.2009.04.006","article-title":"The Anopheles gambiae salivary protein gSG6: an anopheline-specific protein with a blood-feeding role.","volume":"39","author":"F Lombardo","year":"2009","journal-title":"Insect Biochem Mol Biol"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"e2472","DOI":"10.1371\/journal.pone.0002472","article-title":"Novel peptide marker corresponding to salivary protein gSG6 potentially identifies exposure to Anopheles bites.","volume":"3","author":"A Poinsignon","year":"2008","journal-title":"PLoS One"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1186\/1475-2875-8-198","article-title":"Human IgG response to a salivary peptide, gSG6-P1, as a new immuno-epidemiological tool for evaluating low-level exposure to Anopheles bites.","volume":"8","author":"A Poinsignon","year":"2009","journal-title":"Malar J"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"13206","DOI":"10.1073\/pnas.93.23.13206","article-title":"Different response to Plasmodium falciparum malaria in west African sympatric ethnic groups.","volume":"93","author":"D Modiano","year":"1996","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"336","DOI":"10.4269\/ajtmh.1998.59.336","article-title":"Baseline immunity of the population and impact of insecticide-treated curtains on malaria infection.","volume":"59","author":"D Modiano","year":"1998","journal-title":"Am J Trop Med Hyg"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"220","DOI":"10.4269\/ajtmh.1998.58.220","article-title":"Humoral response to Plasmodium falciparum Pf155\/ring-infected erythrocyte surface antigen and Pf332 in three sympatric ethnic groups of Burkina Faso.","volume":"58","author":"D Modiano","year":"1998","journal-title":"Am J Trop Med Hyg"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"392","DOI":"10.3201\/eid1603.090732","article-title":"Serologic markers for detecting malaria in areas of low endemicity, Somalia, 2008.","volume":"16","author":"T Bousema","year":"2010","journal-title":"Emerg Infect Dis"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/j.pt.2007.08.023","article-title":"Serology: a robust indicator of malaria transmission intensity?","volume":"23","author":"P Corran","year":"2007","journal-title":"Trends Parasitol"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"5108","DOI":"10.1073\/pnas.0408725102","article-title":"Estimating medium- and long-term trends in malaria transmission by using serological markers of malaria exposure.","volume":"102","author":"CJ Drakeley","year":"2005","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1016\/0035-9203(88)90007-7","article-title":"Prevalence and levels of antibodies to the circumsporozoite protein of Plasmodium falciparum in an endemic area and their relationship to resistance against malaria infection.","volume":"82","author":"F Esposito","year":"1988","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1111\/j.1365-3024.2006.00805.x","article-title":"Immune interactions between mosquitoes and their hosts.","volume":"28","author":"PF Billingsley","year":"2006","journal-title":"Parasite Immunol"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/S1473-3099(10)70096-7","article-title":"Changes in the burden of malaria in sub-Saharan Africa.","volume":"10","author":"WP O'Meara","year":"2010","journal-title":"Lancet Infect Dis"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"e638","DOI":"10.1371\/journal.pntd.0000638","article-title":"Discovery of markers of exposure specific to bites of Lutzomyia longipalpis, the vector of Leishmania infantum chagasi in Latin America.","volume":"4","author":"C Teixeira","year":"2010","journal-title":"PLoS Negl Trop Dis"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"115","DOI":"10.4269\/ajtmh.2010.09-0684","article-title":"Human antibody response to Anopheles gambiae saliva: an immuno-epidemiological biomarker to evaluate the efficacy of insecticide-treated nets in malaria vector control.","volume":"83","author":"PM Drame","year":"2010","journal-title":"Am J Trop Med Hyg"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1073\/pnas.0709969105","article-title":"Functional deficit of T regulatory cells in Fulani, an ethnic group with low susceptibility to Plasmodium falciparum malaria.","volume":"105","author":"MG Torcia","year":"2008","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1159\/000076787","article-title":"Mosquito allergy: immune mechanisms and recombinant salivary allergens.","volume":"133","author":"Z Peng","year":"2004","journal-title":"Int Arch Allergy Immunol"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1146\/annurev.en.13.010168.001033","article-title":"The Allergic Responses to Insect Bites.","volume":"13","author":"BF Feingold","year":"1968","journal-title":"Annual Review of Entomology"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1038\/158554c0","article-title":"Man&apos;s reaction to mosquito bite.","volume":"158","author":"K Mellanby","year":"1946","journal-title":"Nature"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/S0091-6749(98)70395-1","article-title":"A prospective study of naturally acquired sensitization and subsequent desensitization to mosquito bites and concurrent antibody responses.","volume":"101","author":"Z Peng","year":"1998","journal-title":"J Allergy Clin Immunol"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"6958","DOI":"10.1073\/pnas.1001323107","article-title":"A prospective analysis of the Ab response to Plasmodium falciparum before and after a malaria season by protein microarray.","volume":"107","author":"PD Crompton","year":"2010","journal-title":"Proc Natl Acad Sci U S A"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0017980","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,9]],"date-time":"2019-06-09T05:35:36Z","timestamp":1560058536000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0017980"}},"subtitle":[],"editor":[{"given":"Sylviane","family":"Pied","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2011,3,17]]},"references-count":40,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2011,3,17]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0017980","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,3,17]]}}}