{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T16:41:28Z","timestamp":1760028088245},"reference-count":73,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2011,4,25]],"date-time":"2011-04-25T00:00:00Z","timestamp":1303689600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0018989","type":"journal-article","created":{"date-parts":[[2011,4,25]],"date-time":"2011-04-25T20:53:08Z","timestamp":1303764788000},"page":"e18989","update-policy":"http:\/\/dx.doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":19,"title":["Full-Length L1CAM and Not Its \u03942\u039427 Splice Variant Promotes Metastasis through Induction of Gelatinase Expression"],"prefix":"10.1371","volume":"6","author":[{"given":"Stephanie","family":"Hauser","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Bickel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dirk","family":"Weinspach","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Gerg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael K.","family":"Sch\u00e4fer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Pfeifer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Hazin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Florian","family":"Schelter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrich H.","family":"Weidle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juliane","family":"Ramser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juliane","family":"Volkmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfons","family":"Meindl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manfred","family":"Schmitt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Florian","family":"Schr\u00f6tzlmair","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Altevogt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Achim","family":"Kr\u00fcger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2011,4,25]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1038\/334701a0","article-title":"Neural adhesion molecule L1 as a member of the immunoglobulin superfamily with binding domains similar to fibronectin.","volume":"334","author":"M Moos","year":"1988","journal-title":"Nature"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/BF02919404","article-title":"Variants of human L1 cell adhesion molecule arise through alternate splicing of RNA.","volume":"3","author":"RA Reid","year":"1992","journal-title":"J Mol Neurosci"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1146\/annurev.bi.56.070187.002343","article-title":"Alternative splicing: a ubiquitous mechanism for the generation of multiple protein isoforms from single genes.","volume":"56","author":"RE Breitbart","year":"1987","journal-title":"Annu Rev Biochem"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"556","DOI":"10.2174\/138920208786847971","article-title":"Alternative splicing and tumor progression.","volume":"9","author":"C Ghigna","year":"2008","journal-title":"Curr Genomics"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/S1470-2045(07)70104-3","article-title":"Alternative splicing: an emerging topic in molecular and clinical oncology.","volume":"8","author":"MJ Pajares","year":"2007","journal-title":"Lancet Oncol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"1432","DOI":"10.1016\/j.biocel.2007.02.016","article-title":"Alternative splicing in cancer: noise, functional, or systematic?","volume":"39","author":"RI Skotheim","year":"2007","journal-title":"Int J Biochem Cell Biol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"2635","DOI":"10.1242\/jcs.03053","article-title":"The connection between splicing and cancer.","volume":"119","author":"A Srebrow","year":"2006","journal-title":"J Cell Sci"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"6604","DOI":"10.1038\/sj.onc.1210481","article-title":"CD99 isoforms dictate opposite functions in tumour malignancy and metastases by activating or repressing c-Src kinase activity.","volume":"26","author":"K Scotlandi","year":"2007","journal-title":"Oncogene"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/S0378-1119(97)00614-8","article-title":"The neural cell adhesion molecule L1: genomic organisation and differential splicing is conserved between man and the pufferfish Fugu.","volume":"208","author":"O Coutelle","year":"1998","journal-title":"Gene"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1002\/neu.10052","article-title":"L1 mediated homophilic binding and neurite outgrowth are modulated by alternative splicing of exon 2.","volume":"51","author":"J Jacob","year":"2002","journal-title":"J Neurobiol"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"32738","DOI":"10.1074\/jbc.M105156200","article-title":"Alternative use of a mini exon of the L1 gene affects L1 binding to neural ligands.","volume":"276","author":"E De Angelis","year":"2001","journal-title":"J Biol Chem"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"28038","DOI":"10.1074\/jbc.M804991200","article-title":"Kinetic analysis of L1 homophilic interaction: role of the first four immunoglobulin domains and implications on binding mechanism.","volume":"283","author":"RM Gouveia","year":"2008","journal-title":"J Biol Chem"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"5311","DOI":"10.1523\/JNEUROSCI.18-14-05311.1998","article-title":"The neural cell adhesion molecule L1 interacts with the AP-2 adaptor and is endocytosed via the clathrin-mediated pathway.","volume":"18","author":"H Kamiguchi","year":"1998","journal-title":"J Neurosci"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"37965","DOI":"10.1074\/jbc.274.53.37965","article-title":"Activation of the MAPK signal cascade by the neural cell adhesion molecule L1 requires L1 internalization.","volume":"274","author":"AW Schaefer","year":"1999","journal-title":"J Biol Chem"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1083\/jcb.200203024","article-title":"L1 endocytosis is controlled by a phosphorylation-dephosphorylation cycle stimulated by outside-in signaling by L1.","volume":"157","author":"AW Schaefer","year":"2002","journal-title":"J Cell Biol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"275","DOI":"10.4161\/cam.3.3.8689","article-title":"L1 cell adhesion molecules as regulators of tumor cell invasiveness.","volume":"3","author":"PF Siesser","year":"2009","journal-title":"Cell Adh Migr"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"2425","DOI":"10.1007\/s00018-010-0339-1","article-title":"L1CAM malfunction in the nervous system and human carcinomas.","volume":"67","author":"MK Schafer","year":"2010","journal-title":"Cell Mol Life Sci"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"1749","DOI":"10.1517\/14712598.8.11.1749","article-title":"L1-CAM in cancerous tissues.","volume":"8","author":"N Gavert","year":"2008","journal-title":"Expert Opin Biol Ther"},{"key":"ref19","first-page":"1109","article-title":"Expression and prognostic value of L1-CAM in breast cancer.","volume":"22","author":"C Schroder","year":"2009","journal-title":"Oncol Rep"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1038\/modpathol.3800955","article-title":"L1 is associated with micrometastatic spread and poor outcome in colorectal cancer.","volume":"20","author":"JT Kaifi","year":"2007","journal-title":"Mod Pathol"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1016\/S0140-6736(03)14342-5","article-title":"L1 expression as a predictor of progression and survival in patients with uterine and ovarian carcinomas.","volume":"362","author":"M Fogel","year":"2003","journal-title":"Lancet"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.1245\/s10434-006-9281-8","article-title":"L1 expression as a marker for poor prognosis, tumor progression, and short survival in patients with colorectal cancer.","volume":"14","author":"YJ Boo","year":"2007","journal-title":"Ann Surg Oncol"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"2504","DOI":"10.1158\/0008-5472.CAN-09-3730","article-title":"Therapeutic antibodies to human L1CAM: functional characterization and application in a mouse model for ovarian carcinoma.","volume":"70","author":"S Wolterink","year":"2010","journal-title":"Cancer Res"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.canlet.2007.11.012","article-title":"Antibodies directed against L1-CAM synergize with Genistein in inhibiting growth and survival pathways in SKOV3ip human ovarian cancer cells.","volume":"261","author":"I Novak-Hofer","year":"2008","journal-title":"Cancer Lett"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1158\/0008-5472.CAN-05-1818","article-title":"Efficient inhibition of intra-peritoneal tumor growth and dissemination of human ovarian carcinoma cells in nude mice by anti-L1-cell adhesion molecule monoclonal antibody treatment.","volume":"66","author":"MJ Arlt","year":"2006","journal-title":"Cancer Res"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"10752","DOI":"10.1016\/S0021-9258(19)50082-5","article-title":"Functional expression of a full-length cDNA coding for rat neural cell adhesion molecule L1 mediates homophilic intercellular adhesion and migration of cerebellar neurons.","volume":"267","author":"M Miura","year":"1992","journal-title":"J Biol Chem"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1002\/(SICI)1097-4547(20000601)60:5<579::AID-JNR2>3.0.CO;2-#","article-title":"Differential expression of alternatively spliced neural cell adhesion molecule L1 isoforms during oligodendrocyte maturation.","volume":"60","author":"K Itoh","year":"2000","journal-title":"J Neurosci Res"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"2338","DOI":"10.1046\/j.1471-4159.1996.66062338.x","article-title":"A nonneuronal isoform of cell adhesion molecule L1: tissue-specific expression and functional analysis.","volume":"66","author":"Y Takeda","year":"1996","journal-title":"J Neurochem"},{"key":"ref29","first-page":"375","article-title":"Identification of L1CAM, Jagged2 and Neuromedin U as ovarian cancer-associated antigens.","volume":"13","author":"NI Euer","year":"2005","journal-title":"Oncol Rep"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.2741\/2760","article-title":"The biological role of HGF-MET axis in tumor growth and development of metastasis.","volume":"13","author":"E Lesko","year":"2008","journal-title":"Front Biosci"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1007\/s10555-006-9006-2","article-title":"Transforming growth factor-beta in cancer and metastasis.","volume":"25","author":"SB Jakowlew","year":"2006","journal-title":"Cancer Metastasis Rev"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"659","DOI":"10.2174\/1566524033479447","article-title":"Molecular mechanisms of tumor invasion and metastasis: an integrated view.","volume":"3","author":"RA Cairns","year":"2003","journal-title":"Curr Mol Med"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"2411","DOI":"10.1016\/j.yexcr.2008.04.004","article-title":"The RGD integrin binding site in human L1-CAM is important for nuclear signaling.","volume":"314","author":"D Gast","year":"2008","journal-title":"Exp Cell Res"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1007\/BF01753836","article-title":"Expression of 72 kDa type IV collagenase and invasion activity of human glioma cells.","volume":"12","author":"T Abe","year":"1994","journal-title":"Clin Exp Metastasis"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1006\/gyno.1996.0195","article-title":"Characterization of gelatinases linked to extracellular matrix invasion in ovarian adenocarcinoma: purification of matrix metalloproteinase 2.","volume":"62","author":"TN Young","year":"1996","journal-title":"Gynecol Oncol"},{"key":"ref36","first-page":"5365","article-title":"Levels of matrix metalloproteases in bladder cancer correlate with tumor grade and invasion.","volume":"53","author":"B Davies","year":"1993","journal-title":"Cancer Res"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1038\/sj.pcan.4500750","article-title":"Type IV collagenase (matrix metalloproteinase-2 and -9) in prostate cancer.","volume":"7","author":"L Zhang","year":"2004","journal-title":"Prostate Cancer Prostatic Dis"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S0304-3835(99)00214-1","article-title":"Highly activated matrix metalloproteinase-2 secreted from clones of metastatic lung nodules of nude mice injected with human fibrosarcoma HT1080.","volume":"146","author":"D Togawa","year":"1999","journal-title":"Cancer Lett"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1158\/1541-7786.MCR-07-2032","article-title":"Distinct Functionality of Tumor Cell-Derived Gelatinases during Formation of Liver Metastases.","volume":"6","author":"M Gerg","year":"2008","journal-title":"Mol Cancer Res"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1101\/gad.14.2.163","article-title":"Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis.","volume":"14","author":"Q Yu","year":"2000","journal-title":"Genes Dev"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/j.cub.2007.01.059","article-title":"Spatial regulation of EGFR signaling by Sprouty2.","volume":"17","author":"HJ Kim","year":"2007","journal-title":"Curr Biol"},{"key":"ref42","first-page":"120","article-title":"The complexity of targeting EGFR signalling in cancer: from expression to turnover.","volume":"1766","author":"S Sebastian","year":"2006","journal-title":"Biochim Biophys Acta"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"11370","DOI":"10.1158\/0008-5472.CAN-06-2106","article-title":"Cell adhesion molecule L1 disrupts E-cadherin-containing adherens junctions and increases scattering and motility of MCF7 breast carcinoma cells.","volume":"66","author":"M Shtutman","year":"2006","journal-title":"Cancer Res"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.canlet.2008.12.021","article-title":"L1 cell adhesion molecule (L1CAM) in invasive tumors.","volume":"282","author":"S Raveh","year":"2009","journal-title":"Cancer Lett"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"4517","DOI":"10.1158\/0008-5472.CAN-08-3493","article-title":"Up-regulation of L1CAM in pancreatic duct cells is transforming growth factor beta1- and slug-dependent: role in malignant transformation of pancreatic cancer.","volume":"69","author":"C Geismann","year":"2009","journal-title":"Cancer Res"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1002\/path.2673","article-title":"Up-regulation of L1CAM is linked to loss of hormone receptors and E-cadherin in aggressive subtypes of endometrial carcinomas.","volume":"220","author":"M Huszar","year":"2010","journal-title":"J Pathol"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.bbadis.2008.09.017","article-title":"Alternative splicing and disease.","volume":"1792","author":"J Tazi","year":"2009","journal-title":"Biochim Biophys Acta"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1002\/ijc.20869","article-title":"L1 augments cell migration and tumor growth but not beta3 integrin expression in ovarian carcinomas.","volume":"115","author":"D Gast","year":"2005","journal-title":"Int J Cancer"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1038\/sj.onc.1210747","article-title":"The cytoplasmic part of L1-CAM controls growth and gene expression in human tumors that is reversed by therapeutic antibodies.","volume":"27","author":"D Gast","year":"2008","journal-title":"Oncogene"},{"key":"ref50","first-page":"293","article-title":"Metastasis mechanisms.","volume":"1796","author":"TR Geiger","year":"2009","journal-title":"Biochim Biophys Acta"},{"key":"ref51","first-page":"37","article-title":"Gelatinase-mediated migration and invasion of cancer cells.","volume":"1755","author":"M Bjorklund","year":"2005","journal-title":"Biochim Biophys Acta"},{"key":"ref52","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1016\/j.biomaterials.2004.04.045","article-title":"Mechanical properties, proteolytic degradability and biological modifications affect angiogenic process extension into native and modified fibrin matrices in vitro.","volume":"26","author":"L Urech","year":"2005","journal-title":"Biomaterials"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.conb.2008.07.015","article-title":"L1 and NCAM adhesion molecules as signaling coreceptors in neuronal migration and process outgrowth.","volume":"18","author":"RS Schmid","year":"2008","journal-title":"Curr Opin Neurobiol"},{"key":"ref54","doi-asserted-by":"crossref","first-page":"2135","DOI":"10.1242\/jcs.069542","article-title":"Nuclear factor-kappaB signaling and ezrin are essential for L1-mediated metastasis of colon cancer cells.","volume":"123","author":"N Gavert","year":"2010","journal-title":"J Cell Sci"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"4160","DOI":"10.1021\/bi702433q","article-title":"Characterization of the neuron-specific L1-CAM cytoplasmic tail: naturally disordered in solution it exercises different binding modes for different adaptor proteins.","volume":"47","author":"S Tyukhtenko","year":"2008","journal-title":"Biochemistry"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"28880","DOI":"10.1074\/jbc.M404075200","article-title":"Extracellular signal-regulated kinase (ERK)-dependent gene expression contributes to L1 cell adhesion molecule-dependent motility and invasion.","volume":"279","author":"S Silletti","year":"2004","journal-title":"J Biol Chem"},{"key":"ref57","doi-asserted-by":"crossref","first-page":"2003","DOI":"10.1091\/mbc.E03-05-0333","article-title":"Activation of EGF receptor kinase by L1-mediated homophilic cell interactions.","volume":"15","author":"R Islam","year":"2004","journal-title":"Mol Biol Cell"},{"key":"ref58","doi-asserted-by":"crossref","first-page":"17615","DOI":"10.1073\/pnas.0906541106","article-title":"Endosomes: a legitimate platform for the signaling train.","volume":"106","author":"JE Murphy","year":"2009","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref59","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1111\/j.1471-0528.1989.tb03341.x","article-title":"Revised FIGO staging for gynaecological cancer.","volume":"96","author":"JH Shepherd","year":"1989","journal-title":"Br J Obstet Gynaecol"},{"key":"ref60","first-page":"1751","article-title":"Heterogeneity of malignant cells from a human colonic carcinoma.","volume":"41","author":"MG Brattain","year":"1981","journal-title":"Cancer Res"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"8608","DOI":"10.1158\/0008-5472.CAN-05-1572","article-title":"Reduction of experimental human fibrosarcoma lung metastasis in mice by adenovirus-mediated cystatin C overexpression in the host.","volume":"65","author":"C Kopitz","year":"2005","journal-title":"Cancer Res"},{"key":"ref62","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1002\/ijc.2910580222","article-title":"Scattered micrometastases visualized at the single-cell level: detection and re-isolation of lacZ-labeled metastasized lymphoma cells.","volume":"58","author":"A Kr\u00fcger","year":"1994","journal-title":"Int J Cancer"},{"key":"ref63","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1093\/nar\/23.4.628","article-title":"A transient three-plasmid expression system for the production of high titer retroviral vectors.","volume":"23","author":"Y Soneoka","year":"1995","journal-title":"Nucleic Acids Res"},{"key":"ref64","doi-asserted-by":"crossref","first-page":"9564","DOI":"10.1073\/pnas.91.20.9564","article-title":"A general method for the generation of high-titer, pantropic retroviral vectors: highly efficient infection of primary hepatocytes.","volume":"91","author":"JK Yee","year":"1994","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref65","first-page":"5543","article-title":"Increase in Gelatinase-specificity of Matrix Metalloproteinase Inhibitors Correlates with Antimetastatic Efficacy in a T-Cell Lymphoma Model.","volume":"62","author":"M Arlt","year":"2002","journal-title":"Cancer Res"},{"key":"ref66","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1016\/0169-328X(95)00027-P","article-title":"Exon 2 of the gene for neural cell adhesion molecule L1 is alternatively spliced in B cells.","volume":"30","author":"M Jouet","year":"1995","journal-title":"Brain Res Mol Brain Res"},{"key":"ref67","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1083\/jcb.200101099","article-title":"Ectodomain shedding of L1 adhesion molecule promotes cell migration by autocrine binding to integrins.","volume":"155","author":"S Mechtersheimer","year":"2001","journal-title":"J Cell Biol"},{"key":"ref68","doi-asserted-by":"crossref","first-page":"3523","DOI":"10.1158\/0008-5472.CAN-04-3570","article-title":"Antimetastatic activity of a novel mechanism-based gelatinase inhibitor.","volume":"65","author":"A Kr\u00fcger","year":"2005","journal-title":"Cancer Res"},{"key":"ref69","doi-asserted-by":"crossref","first-page":"5243","DOI":"10.1242\/jcs.02633","article-title":"Distribution and dynamics of Lamp1-containing endocytic organelles in fibroblasts deficient in BLOC-3.","volume":"118","author":"JM Falcon-Perez","year":"2005","journal-title":"J Cell Sci"},{"key":"ref70","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/j.cell.2005.02.017","article-title":"Modulation of receptor recycling and degradation by the endosomal kinesin KIF16B.","volume":"121","author":"S Hoepfner","year":"2005","journal-title":"Cell"},{"key":"ref71","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1083\/jcb.142.4.923","article-title":"An endocytosed TGN38 chimeric protein is delivered to the TGN after trafficking through the endocytic recycling compartment in CHO cells.","volume":"142","author":"RN Ghosh","year":"1998","journal-title":"J Cell Biol"},{"key":"ref72","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1038\/35055042","article-title":"Multicolour imaging of post-Golgi sorting and trafficking in live cells.","volume":"3","author":"P Keller","year":"2001","journal-title":"Nat Cell Biol"},{"key":"ref73","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.nbd.2010.05.029","article-title":"L1 syndrome mutations impair neuronal L1 function at different levels by divergent mechanisms.","volume":"40","author":"MK Sch\u00e4fer","year":"2010","journal-title":"Neurobiol Dis"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0018989","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,11,22]],"date-time":"2021-11-22T06:06:50Z","timestamp":1637561210000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0018989"}},"subtitle":[],"editor":[{"given":"Kelvin Yuen Kwong","family":"Chan","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2011,4,25]]},"references-count":73,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2011,4,25]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0018989","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,4,25]]}}}