{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T02:50:01Z","timestamp":1791082201388,"version":"4.1.0"},"reference-count":33,"publisher":"Public Library of Science (PLoS)","issue":"9","license":[{"start":{"date-parts":[[2011,9,20]],"date-time":"2011-09-20T00:00:00Z","timestamp":1316476800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0024622","type":"journal-article","created":{"date-parts":[[2011,9,20]],"date-time":"2011-09-20T20:55:26Z","timestamp":1316552126000},"page":"e24622","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":20,"title":["Th17 Cells Are Involved in the Local Control of Tumor Progression in Primary Intraocular Lymphoma"],"prefix":"10.1371","volume":"6","author":[{"given":"Claire","family":"Galand","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabrina","family":"Donnou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucile","family":"Crozet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00e9verine","family":"Brunet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Val\u00e9rie","family":"Touitou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanane","family":"Ouakrim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolf Herman","family":"Fridman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Saut\u00e8s-Fridman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvain","family":"Fisson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2011,9,20]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/ijc.22719","article-title":"The non-Hodgkin lymphomas: A review of the epidemiologic literature.","volume":"120","author":"DD Alexander","year":"2007","journal-title":"Int J Cancer"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1076\/ocii.8.4.243.6463","article-title":"Ocular and central nervous system lymphoma: clinical features and diagnosis.","volume":"8","author":"N Cassoux","year":"2000","journal-title":"Ocul Immunol Inflamm"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"3223","DOI":"10.1167\/iovs.07-0008","article-title":"Impaired th1\/tc1 cytokine production of tumor-infiltrating lymphocytes in a model of primary intraocular B-cell lymphoma.","volume":"48","author":"V Touitou","year":"2007","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"2159","DOI":"10.1056\/NEJMoa041869","article-title":"Prediction of survival in follicular lymphoma based on molecular features of tumor-infiltrating immune cells.","volume":"351","author":"SS Dave","year":"2004","journal-title":"N Engl J Med"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"3639","DOI":"10.1182\/blood-2005-08-3376","article-title":"Intratumoral CD4+CD25+ regulatory T-cell-mediated suppression of infiltrating CD4+ T cells in B-cell non-Hodgkin lymphoma.","volume":"107","author":"Z-Z Yang","year":"2006","journal-title":"Blood"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1182\/blood-2009-03-208249","article-title":"Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments.","volume":"114","author":"I Kryczek","year":"2009","journal-title":"Blood"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1016\/j.immuni.2009.09.014","article-title":"T helper 17 cells promote cytotoxic T cell activation in tumor immunity.","volume":"31","author":"N Martin-Orozco","year":"2009","journal-title":"Immunity"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1182\/blood-2007-11-120998","article-title":"Tumor-specific Th17-polarized cells eradicate large established melanoma.","volume":"112","author":"P Muranski","year":"2008","journal-title":"Blood"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1016\/j.immuni.2008.03.004","article-title":"The biological functions of T helper 17 cell effector cytokines in inflammation.","volume":"28","author":"W Ouyang","year":"2008","journal-title":"Immunity"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"776","DOI":"10.5483\/BMBRep.2009.42.12.776","article-title":"Th17 responses and host defense against microorganisms: an overview.","volume":"42","author":"FL van de Veerdonk","year":"2009","journal-title":"BMB Rep"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1111\/j.1749-6632.2009.05133.x","article-title":"Th1 and Th17 cells: adversaries and collaborators.","volume":"1183","author":"JM Damsker","year":"2010","journal-title":"Ann N Y Acad Sci"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1038\/nm1585","article-title":"TH17 cells contribute to uveitis and scleritis and are expanded by IL-2 and inhibited by IL-27\/STAT1.","volume":"13","author":"A Amadi-Obi","year":"2007","journal-title":"Nat Med"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"348","DOI":"10.4049\/jimmunol.136.1.348","article-title":"Different phenotypic variants of the mouse B cell tumor A20\/2J are selected by antigen- and mitogen-triggered cytotoxicity of L3T4-positive, I-A-restricted T cell clones.","volume":"136","author":"B Jones","year":"1986","journal-title":"J Immunol"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1158\/0008-5472.CAN-10-2907","article-title":"Clinical impact of different classes of infiltrating T cytotoxic and helper cells (Th1, th2, treg, th17) in patients with colorectal cancer.","volume":"71","author":"M Tosolini","year":"2011","journal-title":"Cancer Res"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1182\/blood-2009-03-208249","article-title":"Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments.","volume":"114","author":"I Kryczek","year":"2009","journal-title":"Blood"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"e15390","DOI":"10.1371\/journal.pone.0015390","article-title":"The presence of IL-17A and T helper 17 cells in experimental mouse brain tumors and human glioma.","volume":"5","author":"DA Wainwright","year":"2010","journal-title":"PLoS ONE"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"1630","DOI":"10.4049\/jimmunol.0902813","article-title":"Tumor microenvironments direct the recruitment and expansion of human Th17 cells.","volume":"184","author":"X Su","year":"2010","journal-title":"J Immunol"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.ccr.2009.06.017","article-title":"Polarization of tumor-associated neutrophil phenotype by TGF-beta: \u00abN1\u00bb versus \u00abN2\u00bb TAN.","volume":"16","author":"ZG Fridlender","year":"2009","journal-title":"Cancer Cell"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"5653","DOI":"10.1038\/onc.2010.367","article-title":"Up for Mischief? IL-17\/Th17 in the tumour microenvironment.","volume":"29","author":"E Maniati","year":"2010","journal-title":"Oncogene"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1038\/nri2742","article-title":"T(H)17 cells in tumour immunity and immunotherapy.","volume":"10","author":"W Zou","year":"2010","journal-title":"Nat Rev Immunol"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"5522","DOI":"10.1158\/0008-5472.CAN-09-0266","article-title":"Malignant B cells skew the balance of regulatory T cells and TH17 cells in B-cell non-Hodgkin's lymphoma.","volume":"69","author":"Z-Z Yang","year":"2009","journal-title":"Cancer Res"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"375","DOI":"10.3109\/09273940903434804","article-title":"The future of primary intraocular lymphoma (retinal lymphoma).","volume":"17","author":"C-C Chan","year":"2009","journal-title":"Ocul Immunol Inflamm"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1002\/eji.200839050","article-title":"Human Th17 cells: are they different from murine Th17 cells?","volume":"39","author":"F Annunziato","year":"2009","journal-title":"Eur J Immunol"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1038\/35040504","article-title":"Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function.","volume":"408","author":"J Parrish-Novak","year":"2000","journal-title":"Nature"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1016\/j.ajpath.2010.10.043","article-title":"IL-21 and IL-21 receptor expression in lymphocytes and neurons in multiple sclerosis brain.","volume":"178","author":"JS Tzartos","year":"2011","journal-title":"Am J Pathol"},{"key":"ref26","first-page":"3698","article-title":"Interleukin 17, a T-cell-derived cytokine, promotes tumorigenicity of human cervical tumors in nude mice.","volume":"59","author":"E Tartour","year":"1999","journal-title":"Cancer Res"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"2114","DOI":"10.1182\/blood.V99.6.2114","article-title":"Interleukin-17 inhibits tumor cell growth by means of a T-cell\u2013dependent mechanism.","volume":"99","author":"F Benchetrit","year":"2002","journal-title":"Blood"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1159\/000119878","article-title":"Animal models of intraocular lymphomas.","volume":"40","author":"V Touitou","year":"2008","journal-title":"Ophthalmic Res"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1111\/j.1600-0897.2006.00366.x","article-title":"The Effect of Interleukin-17 on the Proliferation and Invasion of JEG-3 Human Choriocarcinoma Cells.","volume":"55","author":"S Pongcharoen","year":"2006","journal-title":"American Journal of Reproductive Immunology"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"2620","DOI":"10.1182\/blood-2002-05-1461","article-title":"Interleukin-17 promotes angiogenesis and tumor growth.","volume":"101","author":"M Numasaki","year":"2003","journal-title":"Blood"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.canlet.2007.06.001","article-title":"High IL-21 receptor expression and apoptosis induction by IL-21 in follicular lymphoma.","volume":"256","author":"N Akamatsu","year":"2007","journal-title":"Cancer Lett"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1517\/14712598.8.9.1295","article-title":"Interleukin-21: biology and application to cancer therapy.","volume":"8","author":"DJ Andorsky","year":"2008","journal-title":"Expert Opin Biol Ther"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"1774","DOI":"10.1136\/gut.2006.093187","article-title":"Control of matrix metalloproteinase production in human intestinal fibroblasts by interleukin 21.","volume":"55","author":"G Monteleone","year":"2006","journal-title":"Gut"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0024622","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,9]],"date-time":"2023-06-09T20:35:23Z","timestamp":1686342923000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0024622"}},"subtitle":[],"editor":[{"given":"Jean","family":"Kanellopoulos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2011,9,20]]},"references-count":33,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2011,9,20]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0024622","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,9,20]]}}}