{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T17:59:52Z","timestamp":1784051992235,"version":"3.55.0"},"reference-count":53,"publisher":"Public Library of Science (PLoS)","issue":"10","license":[{"start":{"date-parts":[[2011,10,14]],"date-time":"2011-10-14T00:00:00Z","timestamp":1318550400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0026382","type":"journal-article","created":{"date-parts":[[2011,10,14]],"date-time":"2011-10-14T21:21:02Z","timestamp":1318627262000},"page":"e26382","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":62,"title":["HDAC Activity Is Required during Xenopus Tail Regeneration"],"prefix":"10.1371","volume":"6","author":[{"given":"Ai-Sun","family":"Tseng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K\u00e1tia","family":"Carneiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joan M.","family":"Lemire","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Levin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2011,10,14]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1111\/j.1440-169X.2007.00912.x","article-title":"Tail regeneration in the Xenopus tadpole.","volume":"49","author":"M Mochii","year":"2007","journal-title":"Dev Growth Differ"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1002\/dvdy.21890","article-title":"Beyond early development: Xenopus as an emerging model for the study of regenerative mechanisms.","volume":"238","author":"CW Beck","year":"2009","journal-title":"Dev Dyn"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1098\/rstb.2004.1463","article-title":"Cellular and molecular mechanisms of regeneration in Xenopus.","volume":"359","author":"JM Slack","year":"2004","journal-title":"Philos Trans R Soc Lond B Biol Sci"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1177\/154405910808700909","article-title":"Tail regeneration in <italic>Xenopus<\/italic> laevis as a model for understanding tissue repair.","volume":"87","author":"AS Tseng","year":"2008","journal-title":"J Dent Res"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.ydbio.2007.12.031","article-title":"TGF-beta signaling is required for multiple processes during Xenopus tail regeneration.","volume":"315","author":"DM Ho","year":"2008","journal-title":"Dev Biol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.ydbio.2009.08.028","article-title":"Electric currents in Xenopus tadpole tail regeneration.","volume":"335","author":"B Reid","year":"2009","journal-title":"Dev Biol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1242\/dev.02812","article-title":"H+ pump-dependent changes in membrane voltage are an early mechanism necessary and sufficient to induce Xenopus tail regeneration.","volume":"134","author":"DS Adams","year":"2007","journal-title":"Development"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"13192","DOI":"10.1523\/JNEUROSCI.3315-10.2010","article-title":"Induction of vertebrate regeneration by a transient sodium current.","volume":"30","author":"AS Tseng","year":"2010","journal-title":"J Neurosci"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"2987","DOI":"10.1242\/dev.035501","article-title":"Early requirement of Hyaluronan for tail regeneration in Xenopus tadpoles.","volume":"136","author":"EG Contreras","year":"2009","journal-title":"Development"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"2323","DOI":"10.1242\/dev.033985","article-title":"Suppression of the immune response potentiates tadpole tail regeneration during the refractory period.","volume":"136","author":"T Fukazawa","year":"2009","journal-title":"Development"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.mod.2008.10.002","article-title":"Xenopus Wnt-5a induces an ectopic larval tail at injured site, suggesting a crucial role for noncanonical Wnt signal in tail regeneration.","volume":"126","author":"T Sugiura","year":"2009","journal-title":"Mech Dev"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1016\/j.mod.2006.07.001","article-title":"Temporal requirement for bone morphogenetic proteins in regeneration of the tail and limb of Xenopus tadpoles.","volume":"123","author":"CW Beck","year":"2006","journal-title":"Mech Dev"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/S1534-5807(03)00233-8","article-title":"Molecular pathways needed for regeneration of spinal cord and muscle in a vertebrate.","volume":"5","author":"CW Beck","year":"2003","journal-title":"Dev Cell"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"1611","DOI":"10.1242\/dev.126.8.1611","article-title":"A developmental pathway controlling outgrowth of the Xenopus tail bud.","volume":"126","author":"CW Beck","year":"1999","journal-title":"Development"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1038\/embor.2009.102","article-title":"Epigenetic reprogramming during wound healing: loss of polycomb-mediated silencing may enable upregulation of repair genes.","volume":"10","author":"T Shaw","year":"2009","journal-title":"EMBO Rep"},{"key":"ref16","article-title":"Aberrant DNA Methylation of Matrix Remodeling and Cell Adhesion Related Genes in Pterygium.","volume":"6","author":"AK Riau","year":"2011"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"13657","DOI":"10.1074\/jbc.M110.204800","article-title":"Mass Spectrometric Studies on Epigenetic Interaction Networks in Cell Differentiation.","volume":"286","author":"L Xiong","year":"2011","journal-title":"J Biol Chem"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1128\/MMBR.64.2.435-459.2000","article-title":"Acetylation of histones and transcription-related factors.","volume":"64","author":"DE Sterner","year":"2000","journal-title":"Microbiol Mol Biol Rev"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.tig.2004.02.007","article-title":"Phosphorylation of histone H3: a balancing act between chromosome condensation and transcriptional activation.","volume":"20","author":"SJ Nowak","year":"2004","journal-title":"Trends Genet"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1093\/nar\/27.3.711","article-title":"Chromatin disruption and modification.","volume":"27","author":"AP Wolffe","year":"1999","journal-title":"Nucleic Acids Res"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"4408","DOI":"10.1074\/jbc.M606773200","article-title":"Cross-talk between histone modifications in response to histone deacetylase inhibitors: MLL4 links histone H3 acetylation and histone H3K4 methylation.","volume":"282","author":"KP Nightingale","year":"2007","journal-title":"J Biol Chem"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1038\/nrg2485","article-title":"The many roles of histone deacetylases in development and physiology: implications for disease and therapy.","volume":"10","author":"M Haberland","year":"2009","journal-title":"Nat Rev Genet"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1016\/j.drudis.2009.06.008","article-title":"Histone acetyl transferases as emerging drug targets.","volume":"14","author":"FJ Dekker","year":"2009","journal-title":"Drug Discov Today"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1093\/embo-reports\/kvf053","article-title":"Histone acetylation: a switch between repressive and permissive chromatin. Second in review series on chromatin dynamics.","volume":"3","author":"A Eberharter","year":"2002","journal-title":"EMBO Rep"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"3693","DOI":"10.1093\/nar\/25.18.3693","article-title":"Histone deacetylases, acetoin utilization proteins and acetylpolyamine amidohydrolases are members of an ancient protein superfamily.","volume":"25","author":"DD Leipe","year":"1997","journal-title":"Nucleic Acids Res"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"8242","DOI":"10.1073\/pnas.1000478107","article-title":"Histone deacetylase 1 (HDAC1), but not HDAC2, controls embryonic stem cell differentiation.","volume":"107","author":"OM Dovey","year":"2010","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"1790","DOI":"10.1101\/gad.1563807","article-title":"Histone deacetylases 1 and 2 redundantly regulate cardiac morphogenesis, growth, and contractility.","volume":"21","author":"RL Montgomery","year":"2007","journal-title":"Genes Dev"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1101\/gad.1809209","article-title":"Epigenetic control of skull morphogenesis by histone deacetylase 8.","volume":"23","author":"M Haberland","year":"2009","journal-title":"Genes Dev"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1038\/387043a0","article-title":"A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression.","volume":"387","author":"T Heinzel","year":"1997","journal-title":"Nature"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/S0092-8674(00)80215-9","article-title":"Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression.","volume":"89","author":"CD Laherty","year":"1997","journal-title":"Cell"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/0092-8674(93)90661-9","article-title":"Mad: a heterodimeric partner for Max that antagonizes Myc transcriptional activity.","volume":"72","author":"DE Ayer","year":"1993","journal-title":"Cell"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.ydbio.2007.09.022","article-title":"Correlation between Shh expression and DNA methylation status of the limb-specific Shh enhancer region during limb regeneration in amphibians.","volume":"312","author":"N Yakushiji","year":"2007","journal-title":"Dev Biol"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"19889","DOI":"10.1073\/pnas.0904132106","article-title":"A histone demethylase is necessary for regeneration in zebrafish.","volume":"106","author":"S Stewart","year":"2009","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref34","first-page":"769","article-title":"Multiple stage-dependent roles for histone deacetylases during amphibian embryogenesis: implications for the involvement of extracellular matrix remodeling.","volume":"44","author":"S Damjanovski","year":"2000","journal-title":"Int J Dev Biol"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.molcel.2010.01.001","article-title":"A DNAJB chaperone subfamily with HDAC-dependent activities suppresses toxic protein aggregation.","volume":"37","author":"J Hageman","journal-title":"Mol Cell"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"D607","DOI":"10.1093\/nar\/gkp953","article-title":"Xenbase: gene expression and improved integration.","volume":"38","author":"JB Bowes","year":"2009","journal-title":"Nucleic Acids Res"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"17174","DOI":"10.1016\/S0021-9258(17)44885-X","article-title":"Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A.","volume":"265","author":"M Yoshida","year":"1990","journal-title":"J Biol Chem"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"36734","DOI":"10.1074\/jbc.M101287200","article-title":"Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen.","volume":"276","author":"CJ Phiel","year":"2001","journal-title":"J Biol Chem"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/1471-213X-11-29","article-title":"Histone deacetylase activity is necessary for left-right patterning during vertebrate development.","volume":"11","author":"K Carneiro","year":"2011","journal-title":"BMC Dev Biol"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1101\/gad.11.1.44","article-title":"Mnt, a novel Max-interacting protein is coexpressed with Myc in proliferating cells and mediates repression at Myc binding sites.","volume":"11","author":"PJ Hurlin","year":"1997","journal-title":"Genes Dev"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1146\/annurev.biochem.76.052705.162114","article-title":"Functions of site-specific histone acetylation and deacetylation.","volume":"76","author":"MD Shahbazian","year":"2007","journal-title":"Annu Rev Biochem"},{"key":"ref42","first-page":"990","article-title":"[NF-kappaB modulates activation of the BMP-2 gene by trichostatin A].","volume":"42","author":"X Li","year":"2008","journal-title":"Mol Biol (Mosk)"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1016\/j.surg.2008.08.027","article-title":"Histone deacetylase inhibitors upregulate Notch-1 and inhibit growth in pheochromocytoma cells.","volume":"144","author":"JT Adler","year":"2008","journal-title":"Surgery"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"5420","DOI":"10.1038\/sj.onc.1210610","article-title":"Histone deacetylases and cancer.","volume":"26","author":"MA Glozak","year":"2007","journal-title":"Oncogene"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1002\/jcb.22185","article-title":"Histone deacetylase inhibitors: Potential in cancer therapy.","volume":"107","author":"PA Marks","year":"2009","journal-title":"J Cell Biochem"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1158\/1535-7163.MCT-08-0585","article-title":"Notch1 mediates growth suppression of papillary and follicular thyroid cancer cells by histone deacetylase inhibitors.","volume":"8","author":"X Xiao","year":"2009","journal-title":"Mol Cancer Ther"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1073\/pnas.2536759100","article-title":"Transcriptional signature of histone deacetylase inhibition in multiple myeloma: biological and clinical implications.","volume":"101","author":"CS Mitsiades","year":"2004","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref48","article-title":"Normal Table of Xenopus laevis.","author":"PD Nieukoop","year":"1967"},{"key":"ref49","article-title":"Early Development of Xenopus Laevis.","author":"HL Sive","year":"2000"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/S0091-679X(08)60307-6","article-title":"In situ hybridization: an improved whole-mount method for Xenopus embryos.","volume":"36","author":"RM Harland","year":"1991","journal-title":"Methods Cell Biol"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.1126\/science.2402639","article-title":"Xotch, the Xenopus homolog of Drosophila notch.","volume":"249","author":"C Coffman","year":"1990","journal-title":"Science"},{"key":"ref52","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1006\/dbio.1999.9374","article-title":"Inhibitory patterning of the anterior neural plate in Xenopus by homeodomain factors Dlx3 and Msx1.","volume":"212","author":"JA Feledy","year":"1999","journal-title":"Dev Biol"},{"key":"ref53","article-title":"Early Development of Xenopus Laevis: A Laboratory Manual.","author":"GR Sive HL","year":"2000"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0026382","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,11]],"date-time":"2021-12-11T01:19:06Z","timestamp":1639185546000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0026382"}},"subtitle":[],"editor":[{"given":"Alistair P.","family":"McGregor","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2011,10,14]]},"references-count":53,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2011,10,14]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0026382","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,10,14]]}}}