{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T06:28:06Z","timestamp":1777530486007,"version":"3.51.4"},"reference-count":74,"publisher":"Public Library of Science (PLoS)","issue":"11","license":[{"start":{"date-parts":[[2011,11,22]],"date-time":"2011-11-22T00:00:00Z","timestamp":1321920000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0028156","type":"journal-article","created":{"date-parts":[[2011,11,22]],"date-time":"2011-11-22T22:23:54Z","timestamp":1322000634000},"page":"e28156","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":24,"title":["Self-Organizing Circuit Assembly through Spatiotemporally Coordinated Neuronal Migration within Geometric Constraints"],"prefix":"10.1371","volume":"6","author":[{"given":"Yi","family":"Sun","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhuo","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaixuan","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenwen","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yunyan","family":"Xie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bo","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xingyu","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2011,11,22]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.cell.2006.12.021","article-title":"Trekking across the brain: The journey of neuronal migration.","volume":"128","author":"R Ayala","year":"2007","journal-title":"Cell"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1038\/nrn2719","article-title":"Evolution of the neocortex: a perspective from developmental biology.","volume":"10","author":"P Rakic","year":"2009","journal-title":"Nature Reviews Neuroscience"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/j.tins.2004.05.001","article-title":"Patterns of neuronal migration in the embryonic cortex.","volume":"27","author":"AR Kriegstein","year":"2004","journal-title":"Trends in Neurosciences"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1146\/annurev.neuro.26.041002.131058","article-title":"Cell migration in the forebrain.","volume":"26","author":"O Marin","year":"2003","journal-title":"Annual Review of Neuroscience"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1038\/nrg799","article-title":"Life is a journey: A genetic look at neocortical development.","volume":"3","author":"A Gupta","year":"2002","journal-title":"Nature Reviews Genetics"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1038\/nature05300","article-title":"Electrical activity in early neuronal development.","volume":"444","author":"NC Spitzer","year":"2006","journal-title":"Nature"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/j.cell.2007.01.051","article-title":"Long-range Ca2+ signaling from growth cone to soma mediates reversal of neuronal migration induced by Slit-2.","volume":"129","author":"CB Guan","year":"2007","journal-title":"Cell"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1038\/nature09941","article-title":"Self-organizing optic-cup morphogenesis in three-dimensional culture.","volume":"472","author":"M Eiraku","year":"2011","journal-title":"Nature"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1126\/science.1201647","article-title":"Self-Organizing and Stochastic Behaviors During the Regeneration of Hair Stem Cells.","volume":"332","author":"MV Plikus","year":"2011","journal-title":"Science"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1038\/nrm2357","article-title":"Self-organization in cell biology: a brief history.","volume":"9","author":"E Karsenti","year":"2008","journal-title":"Nature Reviews Molecular Cell Biology"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1038\/nature08753","article-title":"A synchronized quorum of genetic clocks.","volume":"463","author":"T Danino","year":"2010","journal-title":"Nature"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"050901","DOI":"10.1103\/PhysRevE.75.050901","article-title":"Towards neuro-memory-chip: Imprinting multiple memories in cultured neural networks.","volume":"75","author":"I Baruchi","year":"2007","journal-title":"Physical Review E"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1038\/nature04701","article-title":"Weak pairwise correlations imply strongly correlated network states in a neural population.","volume":"440","author":"E Schneidman","year":"2006","journal-title":"Nature"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"16332","DOI":"10.1523\/JNEUROSCI.4859-10.2010","article-title":"Dynamics of Excitability over Extended Timescales in Cultured Cortical Neurons.","volume":"30","author":"A Gal","year":"2010","journal-title":"Journal of Neuroscience"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"e2088","DOI":"10.1371\/journal.pone.0002088","article-title":"Long-Term Activity-Dependent Plasticity of Action Potential Propagation Delay and Amplitude in Cortical Networks.","volume":"3","author":"DJ Bakkum","year":"2008","journal-title":"Plos One"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"4605","DOI":"10.1523\/JNEUROSCI.3803-04.2005","article-title":"Activation of early silent synapses by spontaneous synchronous network activity limits the range of neocortical connections.","volume":"25","author":"T Voigt","year":"2005","journal-title":"Journal of Neuroscience"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.aca.2009.05.018","article-title":"Combining nanosurface chemistry and microfluidics for molecular analysis and cell biology.","volume":"650","author":"Y Sun","year":"2009","journal-title":"Analytica Chimica Acta"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1073\/pnas.0408954102","article-title":"Directing cell migration with asymmetric micropatterns.","volume":"102","author":"XY Jiang","year":"2005","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.1126\/science.276.5317.1425","article-title":"Geometric control of cell life and death.","volume":"276","author":"CS Chen","year":"1997","journal-title":"Science"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1146\/annurev.bioeng.3.1.335","article-title":"Soft lithography in biology and biochemistry.","volume":"3","author":"GM Whitesides","year":"2001","journal-title":"Annual Review of Biomedical Engineering"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1038\/nature10137","article-title":"Role of YAP\/TAZ in mechanotransduction.","volume":"474","author":"S Dupont","year":"2011","journal-title":"Nature"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"10333","DOI":"10.1073\/pnas.0500717102","article-title":"Synaptic mechanisms of persistent reverberatory activity in neuronal networks.","volume":"102","author":"PM Lau","year":"2005","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"13581","DOI":"10.1523\/JNEUROSCI.3863-07.2007","article-title":"Synaptic reorganization in scaled networks of controlled size.","volume":"27","author":"NR Wilson","year":"2007","journal-title":"Journal of Neuroscience"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1038\/nphys1099","article-title":"Reliable neuronal logic devices from patterned hippocampal cultures.","volume":"4","author":"O Feinerman","year":"2008","journal-title":"Nature Physics"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"7834","DOI":"10.1073\/pnas.88.17.7834","article-title":"Excitatory and Inhibitory Autaptic Currents in Isolated Hippocampal-Neurons Maintained in Cell-Culture.","volume":"88","author":"JM Bekkers","year":"1991","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"4098","DOI":"10.1523\/JNEUROSCI.08-11-04098.1988","article-title":"Controlled Outgrowth of Dissociated Neurons on Patterned Substrates.","volume":"8","author":"D Kleinfeld","year":"1988","journal-title":"Journal of Neuroscience"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1083\/jcb.103.1.145","article-title":"Differential Contributions of Ng-Cam and N-Cam to Cell-Adhesion in Different Neural Regions.","volume":"103","author":"S Hoffman","year":"1986","journal-title":"Journal of Cell Biology"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1083\/jcb.87.2.370","article-title":"Effects of Fasciculation on the Outgrowth of Neurites from Spinal Ganglia in Culture.","volume":"87","author":"U Rutishauser","year":"1980","journal-title":"Journal of Cell Biology"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"168101","DOI":"10.1103\/PhysRevLett.90.168101","article-title":"Formation of electrically active clusterized neural networks.","volume":"90","author":"R Segev","year":"2003","journal-title":"Physical Review Letters"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1088\/1741-2560\/3\/2\/003","article-title":"Compact self-wiring in cultured neural networks.","volume":"3","author":"R Sorkin","year":"2006","journal-title":"Journal of Neural Engineering"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"1414","DOI":"10.1126\/science.288.5470.1414","article-title":"Spatial patterns in the distribution of tropical tree species.","volume":"288","author":"R Condit","year":"2000","journal-title":"Science"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"3166","DOI":"10.1523\/JNEUROSCI.16-10-03166.1996","article-title":"Clustering of gephyrin at GABAergic but not glutamatergic synapses in cultured rat hippocampal neurons.","volume":"16","author":"AM Craig","year":"1996","journal-title":"Journal of Neuroscience"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1146\/annurev-neuro-061010-113717","article-title":"Mechanisms of Inhibition within the Telencephalon: \u201cWhere the Wild Things Are\u201d.","volume":"34","author":"G Fishell","year":"2011","journal-title":"Annual Review of Neuroscience"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1146\/annurev.cellbio.24.110707.175402","article-title":"Many Paths to Synaptic Specificity.","volume":"25","author":"JR Sanes","year":"2009","journal-title":"Annual Review of Cell and Developmental Biology"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.neuron.2010.09.007","article-title":"Molecular Mechanisms of Synaptic Specificity in Developing Neural Circuits.","volume":"68","author":"ME Williams","year":"2010","journal-title":"Neuron"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1126\/science.274.5290.1133","article-title":"Synaptic activity and the construction of cortical circuits.","volume":"274","author":"LC Katz","year":"1996","journal-title":"Science"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1038\/nphys1306","article-title":"Directing cell motions on micropatterned ratchets.","volume":"5","author":"G Mahmud","year":"2009","journal-title":"Nature Physics"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"1870","DOI":"10.1126\/science.1089662","article-title":"Communication in neuronal networks.","volume":"301","author":"SB Laughlin","year":"2003","journal-title":"Science"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1038\/385313a0","article-title":"A tension-based theory of morphogenesis and compact wiring in the central nervous system.","volume":"385","author":"DC VanEssen","year":"1997","journal-title":"Nature"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1039\/b927402b","article-title":"The function of mechanical tension in neuronal and network development.","volume":"2","author":"A Ayali","year":"2010","journal-title":"Integrative Biology"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"1661","DOI":"10.1016\/j.bpj.2008.10.058","article-title":"The Regulative Role of Neurite Mechanical Tension in Network Development.","volume":"96","author":"A Ayali","year":"2009","journal-title":"Biophysical Journal"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1016\/j.neuroscience.2010.10.022","article-title":"Neuronal soma migration is determined by neurite tension.","volume":"172","author":"Y Hanein","year":"2011","journal-title":"Neuroscience"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"3208","DOI":"10.1016\/j.bpj.2010.09.029","article-title":"Drosophila Neurons Actively Regulate Axonal Tension In Vivo.","volume":"99","author":"J Rajagopalan","year":"2010","journal-title":"Biophysical Journal"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"12611","DOI":"10.1073\/pnas.0901867106","article-title":"Mechanical tension contributes to clustering of neurotransmitter vesicles at presynaptic terminals.","volume":"106","author":"T Saif","year":"2009","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1242\/jcs.37.1.391","article-title":"Mechanical Tension Produced by Nerve-Cells in Tissue-Culture.","volume":"37","author":"D Bray","year":"1979","journal-title":"Journal of Cell Science"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/0166-2236(87)90015-4","article-title":"Growth Cones - Do They Pull or Are They Pushed.","volume":"10","author":"D Bray","year":"1987","journal-title":"Trends in Neurosciences"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1038\/340159a0","article-title":"Direct Evidence That Growth Cones Pull.","volume":"340","author":"P Lamoureux","year":"1989","journal-title":"Nature"},{"key":"ref48","first-page":"507","article-title":"Highly nonrandom features of synaptic connectivity in local cortical circuits.","volume":"3","author":"S Song","year":"2005","journal-title":"Plos Biology"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"e3782","DOI":"10.1371\/journal.pone.0003782","article-title":"Convergence among Non-Sister Dendritic Branches: An Activity-Controlled Mean to Strengthen Network Connectivity.","volume":"3","author":"P Blinder","year":"2008","journal-title":"Plos One"},{"key":"ref50","first-page":"617","article-title":"Segregation of the brain into gray and white matter: A design minimizing conduction delays.","volume":"1","author":"Q Wen","year":"2005","journal-title":"Plos Computational Biology"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"9278","DOI":"10.1073\/pnas.0712207105","article-title":"Geometric constraints on neuronal connectivity facilitate a concise synaptic adhesive code.","volume":"105","author":"S Itzkovitz","year":"2008","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"ref52","doi-asserted-by":"crossref","first-page":"2418","DOI":"10.1126\/science.1070821","article-title":"Self-assembly at all scales.","volume":"295","author":"GM Whitesides","year":"2002","journal-title":"Science"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1126\/science.1058866","article-title":"Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets.","volume":"292","author":"N Lumelsky","year":"2001","journal-title":"Science"},{"key":"ref54","doi-asserted-by":"crossref","first-page":"15921","DOI":"10.1073\/pnas.0904089106","article-title":"Spontaneous cortical activity in awake monkeys composed of neuronal avalanches.","volume":"106","author":"T Petermann","year":"2009","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1126\/science.1194869","article-title":"Universality in the Evolution of Orientation Columns in the Visual Cortex.","volume":"330","author":"M Kaschube","year":"2010","journal-title":"Science"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1038\/nn1447","article-title":"Geometric and functional organization of cortical circuits.","volume":"8","author":"GMG Shepherd","year":"2005","journal-title":"Nature Neuroscience"},{"key":"ref57","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1007\/BF00199545","article-title":"The Connectivity of the Brain - Multilevel Quantitative-Analysis.","volume":"73","author":"JMJ Murre","year":"1995","journal-title":"Biological Cybernetics"},{"key":"ref58","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1038\/nature10360","article-title":"Neocortical excitation\/inhibition balance in information processing and social dysfunction.","volume":"477","author":"O Yizhar","year":"2011","journal-title":"Nature"},{"key":"ref59","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1038\/nature08935","article-title":"Lateral competition for cortical space by layer-specific horizontal circuits.","volume":"464","author":"H Adesnik","year":"2010","journal-title":"Nature"},{"key":"ref60","doi-asserted-by":"crossref","first-page":"e14443","DOI":"10.1371\/journal.pone.0014443","article-title":"Innate Synchronous Oscillations in Freely-Organized Small Neuronal Circuits.","volume":"5","author":"M Shein Idelson","year":"2010","journal-title":"Plos One"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1038\/nature07722","article-title":"Specific synapses develop preferentially among sister excitatory neurons in the neocortex.","volume":"458","author":"Y-C Yu","year":"2009","journal-title":"Nature"},{"key":"ref62","doi-asserted-by":"crossref","first-page":"1352","DOI":"10.1126\/science.1093783","article-title":"Selective differentiation of neural progenitor cells by high-epitope density nanofibers.","volume":"303","author":"GA Silva","year":"2004","journal-title":"Science"},{"key":"ref63","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.neuron.2010.03.022","article-title":"Microfluidic Local Perfusion Chambers for the Visualization and Manipulation of Synapses.","volume":"66","author":"AM Taylor","year":"2010","journal-title":"Neuron"},{"key":"ref64","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1038\/nmeth.1236","article-title":"Colloid-guided assembly of oriented 3D neuronal networks.","volume":"5","author":"S Pautot","year":"2008","journal-title":"Nature Methods"},{"key":"ref65","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1038\/nrn1827","article-title":"Neuroscience nanotechnology: Progress, opportunities and challenges.","volume":"7","author":"GA Silva","year":"2006","journal-title":"Nature Reviews Neuroscience"},{"key":"ref66","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1038\/nrn2575","article-title":"Complex brain networks: graph theoretical analysis of structural and functional systems.","volume":"10","author":"E Bullmore","year":"2009","journal-title":"Nature Reviews Neuroscience"},{"key":"ref67","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1103\/RevModPhys.78.1213","article-title":"Dynamical principles in neuroscience.","volume":"78","author":"MI Rabinovich","year":"2006","journal-title":"Reviews of Modern Physics"},{"key":"ref68","doi-asserted-by":"crossref","first-page":"e15966","DOI":"10.1371\/journal.pone.0015966","article-title":"Two Distinct Filopodia Populations at the Growth Cone Allow to Sense Nanotopographical Extracellular Matrix Cues to Guide Neurite Outgrowth.","volume":"5","author":"KJ Jang","year":"2010","journal-title":"Plos One"},{"key":"ref69","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1002\/anie.200603844","article-title":"A method for patterning multiple types of cells by using electrochemical desorption of self-assembled monolayers within microfluidic channels.","volume":"46","author":"Y Li","year":"2007","journal-title":"Angew Chem Int Ed Engl"},{"key":"ref70","first-page":"4406","article-title":"Using azobenzene-embedded self-assembled monolayers to photochemically control cell adhesion reversibly.","volume":"24","author":"DB Liu","year":"2009","journal-title":"Angew Chem Int Ed Engl,"},{"key":"ref71","doi-asserted-by":"crossref","first-page":"2366","DOI":"10.1021\/ja029485c","article-title":"Electrochemical desorption of self-assembled monolayers noninvasively releases patterned cells from geometrical confinements.","volume":"125","author":"XY Jiang","year":"2003","journal-title":"Journal of the American Chemical Society"},{"key":"ref72","doi-asserted-by":"crossref","first-page":"12542","DOI":"10.1073\/pnas.192457199","article-title":"Gradients of substrate-bound laminin orient axonal specification of neurons.","volume":"99","author":"SKW Dertinger","year":"2002","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"ref73","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.neuron.2008.11.015","article-title":"Coordinated Changes in Dendritic Arborization and Synaptic Strength during Neural Circuit Development.","volume":"61","author":"YR Peng","year":"2009","journal-title":"Neuron"},{"key":"ref74","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1126\/science.1093173","article-title":"Synfire chains and cortical songs: Temporal modules of cortical activity.","volume":"304","author":"R Yuste","year":"2004","journal-title":"Science"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0028156","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,17]],"date-time":"2021-12-17T17:41:20Z","timestamp":1639762880000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0028156"}},"subtitle":[],"editor":[{"given":"Eshel","family":"Ben-Jacob","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2011,11,22]]},"references-count":74,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2011,11,22]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0028156","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,11,22]]}}}