{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T09:56:00Z","timestamp":1790416560063,"version":"4.1.0"},"reference-count":46,"publisher":"Public Library of Science (PLoS)","issue":"1","license":[{"start":{"date-parts":[[2012,1,3]],"date-time":"2012-01-03T00:00:00Z","timestamp":1325548800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/publicdomain\/zero\/1.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0028912","type":"journal-article","created":{"date-parts":[[2012,1,3]],"date-time":"2012-01-03T19:44:09Z","timestamp":1325619849000},"page":"e28912","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":73,"title":["Clinical Subtypes of Depression Are Associated with Specific Metabolic Parameters and Circadian Endocrine Profiles in Women: The Power Study"],"prefix":"10.1371","volume":"7","clinical-trial-number":[{"clinical-trial-number":"nct00006180","registry":"10.18810\/clinical-trials-gov"}],"author":[{"given":"Giovanni","family":"Cizza","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donna S.","family":"Ronsaville","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hayley","family":"Kleitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farideh","family":"Eskandari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sejal","family":"Mistry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Torvik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nina","family":"Sonbolian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James C.","family":"Reynolds","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc R.","family":"Blackman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip W.","family":"Gold","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro E.","family":"Martinez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"for the P.O.W.E.R. (Premenopausal, Osteopenia\/Osteoporosis, Women, Alendronate, Depression) Study Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2012,1,3]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1001\/archpsyc.62.6.617","article-title":"Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication.","volume":"62","author":"RC Kessler","year":"2005","journal-title":"Arch Gen Psychiatry"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/S0165-1781(99)00035-9","article-title":"Prevalence and clinical features of atypical depression in depressed outpatients: a 467-case study.","volume":"86","author":"F Benazzi","year":"1999","journal-title":"Psychiatry Res"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/0165-1781(96)02781-3","article-title":"Biological and clinical validation of atypical depression.","volume":"60","author":"LK McGinn","year":"1996","journal-title":"Psychiatry Res"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1001\/archpsyc.1988.01800260037004","article-title":"Antidepressant specificity in atypical depression.","volume":"45","author":"MR Liebowitz","year":"1988","journal-title":"Arch Gen Psychiatry"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/j.pnpbp.2004.01.006","article-title":"The relationship of regional cerebral blood flow with subtypes of major depression.","volume":"3","author":"KN Fountoulakis","year":"2004","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/0165-0327(85)90073-4","article-title":"Sleep of atypical depressives.","volume":"8","author":"FM Quitkin","year":"1985","journal-title":"J Affect Disord"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1038\/sj.mp.4001032","article-title":"Organization of the stress system and its dysregulation in melancholic and atypical depression: high vs low CRH\/NE states.","volume":"7","author":"PW Gold","year":"2002","journal-title":"Mol Psychiatr"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/0165-0327(87)90030-9","article-title":"Clinical variables and hypothalamic-pituitary-adrenal function in depression. The importance of mood reactivity.","volume":"12","author":"CZ Lemus","year":"1987","journal-title":"J Affect Disord"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.jad.2009.07.012","article-title":"A longitudinal study of cognitive function in melancholic and non-melancholic subtypes of major depressive disorder.","volume":"123","author":"A Withall","year":"2010","journal-title":"J Affect Disord"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.jad.2008.05.015","article-title":"Subtypes of depression in a nationally representative sample.","volume":"113","author":"N Carragher","year":"2009","journal-title":"J Affect Disord"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"2633","DOI":"10.1038\/npp.2009.100","article-title":"Atypical depression: useful concept, but it&apos;s time to revise the DSM-IV criteria.","volume":"34","author":"ME Thase","year":"2009","journal-title":"Neuropsychopharmacology"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1001\/archpsyc.60.8.817","article-title":"Depression with atypical features in the National Comorbidity Survey: classification, description, and consequences.","volume":"60","author":"LS Matza","year":"2003","journal-title":"Arch Gen Psychiatry"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.jad.2004.09.008","article-title":"Gender differences in depression: findings from the STAR*D study.","volume":"87","author":"SM Marcus","year":"2005","journal-title":"J Affect Disord"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.4088\/JCP.v66n0807","article-title":"Clinical and demographic features of atypical depression in outpatients with major depressive disorder: preliminary findings from STAR*D.","volume":"66","author":"JS Novick","year":"2005","journal-title":"J Clin Psychiatry"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/S0010-440X(98)90080-3","article-title":"The high prevalence of \u201csoft\u201d bipolar (II) features in atypical depression.","volume":"39","author":"G Perugi","year":"1998","journal-title":"Compr Psychiatry"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1053\/comp.2002.33498","article-title":"The prevalence of atypical features across mood, anxiety, and personality disorders.","volume":"43","author":"MA Posternak","year":"2002","journal-title":"Compr Psychiatry"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1176\/ajp.152.1.31","article-title":"Atypical depression: clinical aspects and noradrenergic function.","volume":"152","author":"GM Asnis","year":"1995","journal-title":"Am J Psychiatry"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0006-3223(03)00473-6","article-title":"Association of depression with medical illness: does cortisol play a role?","volume":"55","author":"ES Brown","year":"2004","journal-title":"Biol Psychiatry"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/S1043-2760(01)00407-6","article-title":"Depression: a major, unrecognized risk factor for osteoporosis?","volume":"12","author":"G Cizza","year":"2001","journal-title":"Trends Endocrinol Metab"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"2329","DOI":"10.1001\/archinte.167.21.2329","article-title":"Premenopausal, Osteoporosis Women, Alendronate, Depression (POWER) Study Group. Low bone mass in premenopausal women with depression.","volume":"167","author":"F Eskandari","year":"2007","journal-title":"Arch Intern Med"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"2522","DOI":"10.1210\/jc.2004-1667","article-title":"Major depression is associated with significant diurnal elevations in plasma interleukin-6 levels, a shift of its circadian rhythm, and loss of physiological complexity in its secretion: clinical implications.","volume":"90","author":"S Alesci","year":"2005","journal-title":"J Clin Endocrinol Metab"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.2337\/dc09-1940","article-title":"Depression and insulin resistance: cross-sectional associations in young adults.","volume":"33","author":"S Pearson","year":"2010","journal-title":"Diabetes Care"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1093\/aje\/kwg275","article-title":"Is obesity associated with major depression? Results from the Third National Health and Nutrition Examination Survey.","volume":"158","author":"CU Onyike","year":"2003","journal-title":"Am J Epidemiol"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"73","DOI":"10.31887\/DCNS.2011.13.1\/gcizza","article-title":"Major depressive disorder is a risk factor for low bone mass, central obesity, and other medical conditions.","volume":"13","author":"G Cizza","year":"2011","journal-title":"Dialogues Clin Neurosci"},{"key":"ref25","article-title":"Structured Clinical Interview for DSM-IV Axis I Disorders- Patient Edition (SCID I\/P), Version 2.0.","author":"MB First","year":"1997"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1016\/j.metabol.2005.02.006","article-title":"POWER (Premenopausal, Osteopenia\/Osteoporosis, Women, Alendronate, Depression) Study Group. Younger, premenopausal women with major depressive disorder have more abdominal fat and increased serum levels of prothrombotic factors: implications for greater cardiovascular risk.","volume":"54","author":"F Eskandari","year":"2005","journal-title":"Metabolism"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1161\/CIRCULATIONAHA.107.721878","article-title":"Association of insulin resistance and inflammation with peripheral arterial disease: the National Health and Nutrition Examination Survey, 1999 to 2004.","volume":"118","author":"RL Pande","year":"2008","journal-title":"Circulation"},{"key":"ref28","article-title":"<italic>Categorical Data Analysis<\/italic>, 2nd ed","author":"A Agresti","year":"2002"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"1582","DOI":"10.4088\/JCP.09m05398blu","article-title":"Identifying depressive subtypes in a large cohort study: results from the Netherlands Study of Depression and Anxiety (NESDA).","volume":"71","author":"F Lamers","year":"2010","journal-title":"J Clin Psychiatry"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"3320","DOI":"10.2337\/diacare.26.12.3320","article-title":"Diagnosing insulin resistance by simple quantitative methods in subjects with normal glucose metabolism.","volume":"12","author":"JF Ascaso","year":"2003","journal-title":"Diabetes Care"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"2383","DOI":"10.2337\/dc08-0985","article-title":"Depression and type 2 diabetes over the lifespan: a meta-analysis.","volume":"12","author":"B Mezuk","year":"2008","journal-title":"Diabetes Care"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1007\/s11892-009-0010-0","article-title":"Metabolic syndrome and major depressive disorder: co-occurrence and pathophysiologic overlap.","volume":"9","author":"RS McIntyre","year":"2009","journal-title":"Curr Diab Rep"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1111\/j.1749-6632.1995.tb44723.x","article-title":"Corticotropin releasing hormone in the pathophysiology of melancholic and atypical depression and in the mechanism of action of antidepressant drugs.","volume":"771","author":"PW Gold","year":"1995","journal-title":"Ann N Y Acad Sci"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1038\/sj.mp.4000436","article-title":"Endocrine and cytokine correlates of major depression and dysthymia with typical or atypical features.","volume":"4","author":"H Anisman","year":"1999","journal-title":"Mol Psychiatry"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1097\/PSY.0b013e31820ad12b","article-title":"Depression and hypothalamic-pituitary-adrenal activation: a quantitative summary of four decades of research.","volume":"73","author":"C Stetler","year":"2011","journal-title":"Psychosom Med"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/S0893-133X(00)00236-0","article-title":"Twenty-four-hour ACTH and cortisol pulsatility in depressed women.","volume":"25","author":"EA Young","year":"2001","journal-title":"Neuropsychopharmacology"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.4088\/JCP.09m05314blu","article-title":"Low 24-hour adiponectin and high nocturnal leptin concentrations in a case-control study of community-dwelling premenopausal women with major depressive disorder: the Premenopausal, Osteopenia\/Osteoporosis, Women, Alendronate, Depression (POWER) study.","volume":"71","author":"G Cizza","year":"2010","journal-title":"J Clin Psychiatry"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1016\/S0896-6273(01)80035-0","article-title":"Leptin differentially regulates NPY and POMC neurons projecting to the lateral hypothalamic area.","volume":"23","author":"CF Elias","year":"1999","journal-title":"Neuron"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1161\/01.HYP.0000066289.17754.49","article-title":"Interactions between leptin and the human sympathetic system.","volume":"41","author":"N Eikelis","year":"2003","journal-title":"Hypertension"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"8303","DOI":"10.1073\/pnas.0503069102","article-title":"Cardiac implications of increased arterial entry and reversible 24-h central and peripheral norepinephrine levels in melancholia.","volume":"102","author":"PW Gold","year":"2005","journal-title":"Proc Natl Acad Sci USA"},{"key":"ref41","first-page":"648","article-title":"The leptin hypothesis of depression: a potential link between mood disorders and obesity?","volume":"6","author":"XY Lu","year":"2007","journal-title":"Curr Opin Pharmacol"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"2539","DOI":"10.1210\/en.2011-1161","article-title":"Extrahypothalamic effects of leptin: a therapeutic for depression and dementia?","volume":"152","author":"WA Banks","year":"2011","journal-title":"Endocrinology"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1186\/1477-7827-8-115","article-title":"Determinants of menarche.","volume":"8","author":"O Karapanou","year":"2010","journal-title":"Reprod Biol Endocrinol"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/S0165-0327(02)00459-7","article-title":"Early life menstrual characteristics and pregnancy experiences among women with and without major depression: the Harvard study of moods and cycles.","volume":"79","author":"BL Harlow","year":"2004","journal-title":"J Affect Disord"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1055\/s-0030-1252020","article-title":"Depression and osteoporosis: a research synthesis with meta-analysis.","volume":"42","author":"G Cizza","year":"2010","journal-title":"Horm Metab Res"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.tem.2009.05.003","article-title":"Depression as a risk factor for osteoporosis.","volume":"8","author":"G Cizza","year":"2009","journal-title":"Trends Endocrinol Metab"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0028912","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,24]],"date-time":"2021-12-24T00:21:10Z","timestamp":1640305270000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0028912"}},"subtitle":[],"editor":[{"given":"Massimo","family":"Federici","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2012,1,3]]},"references-count":46,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2012,1,3]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0028912","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,1,3]]}}}