{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T13:47:43Z","timestamp":1792072063692,"version":"4.4.0"},"reference-count":79,"publisher":"Public Library of Science (PLoS)","issue":"1","license":[{"start":{"date-parts":[[2012,1,17]],"date-time":"2012-01-17T00:00:00Z","timestamp":1326758400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0029021","type":"journal-article","created":{"date-parts":[[2012,1,17]],"date-time":"2012-01-17T21:44:52Z","timestamp":1326836692000},"page":"e29021","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":76,"title":["Genome-Wide Progesterone Receptor Binding: Cell Type-Specific and Shared Mechanisms in T47D Breast Cancer Cells and Primary Leiomyoma Cells"],"prefix":"10.1371","volume":"7","author":[{"given":"Ping","family":"Yin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damian","family":"Roqueiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonas K.","family":"Owen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonia","family":"Navarro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana","family":"Monsivais","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John S.","family":"Coon V","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Julie","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Dai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serdar E.","family":"Bulun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2012,1,17]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1023\/A:1018760721173","article-title":"Progesterone signaling and mammary gland morphogenesis.","volume":"4","author":"G Shyamala","year":"1999","journal-title":"J Mammary Gland Biol Neoplasia"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1751","DOI":"10.1126\/science.289.5485.1751","article-title":"Subgroup of reproductive functions of progesterone mediated by progesterone receptor-B isoform.","volume":"289","author":"B Mulac-Jericevic","year":"2000","journal-title":"Science"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1016\/S0039-128X(03)00126-0","article-title":"Progesterone-dependent regulation of female reproductive activity by two distinct progesterone receptor isoforms.","volume":"68","author":"OM Conneely","year":"2003","journal-title":"Steroids"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.mce.2005.11.041","article-title":"Progesterone resistance in endometriosis: link to failure to metabolize estradiol.","volume":"248","author":"SE Bulun","year":"2006","journal-title":"Mol Cell Endocrinol"},{"key":"ref5","article-title":"The role of progesterone signaling in the pathogenesis of uterine leiomyoma.","author":"JJ Kim","year":"2011","journal-title":"Mol Cell Endocrinol."},{"key":"ref6","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1001\/jama.290.13.1739","article-title":"Effects of estrogen plus progestin on gynecologic cancers and associated diagnostic procedures: the Women&apos;s Health Initiative randomized trial.","volume":"290","author":"GL Anderson","year":"2003","journal-title":"JAMA"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"1722","DOI":"10.1158\/0008-5472.CAN-09-2612","article-title":"Transcription factor KLF11 integrates progesterone receptor signaling and proliferation in uterine leiomyoma cells.","volume":"70","author":"P Yin","year":"2010","journal-title":"Cancer Res"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"1701","DOI":"10.1001\/jama.291.14.1701","article-title":"Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women&apos;s Health Initiative randomized controlled trial.","volume":"291","author":"GL Anderson","year":"2004","journal-title":"JAMA"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"3243","DOI":"10.1001\/jama.289.24.3243","article-title":"Influence of estrogen plus progestin on breast cancer and mammography in healthy postmenopausal women: the Women&apos;s Health Initiative Randomized Trial.","volume":"289","author":"RT Chlebowski","year":"2003","journal-title":"JAMA"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.1095\/biolreprod63.5.1322","article-title":"Altered hormonal responsiveness of proliferation and apoptosis during myometrial maturation and the development of uterine leiomyomas in the rat.","volume":"63","author":"KD Burroughs","year":"2000","journal-title":"Biol Reprod"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1002\/1097-4652(2000)9999:999<000::AID-JCP1040>3.0.CO;2-E","article-title":"17-beta estradiol elicits an autocrine leiomyoma cell proliferation: evidence for a stimulation of protein kinase-dependent pathway.","volume":"186","author":"A Barbarisi","year":"2001","journal-title":"J Cell Physiol"},{"key":"ref12","first-page":"293","article-title":"Increased expression of Bcl-2 protein in human uterine leiomyoma and its up-regulation by progesterone.","volume":"82","author":"H Matsuo","year":"1997","journal-title":"J Clin Endocrinol Metab"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"1296","DOI":"10.1210\/jc.2005-2379","article-title":"A novel selective progesterone receptor modulator asoprisnil (J867) inhibits proliferation and induces apoptosis in cultured human uterine leiomyoma cells in the absence of comparable effects on myometrial cells.","volume":"91","author":"W Chen","year":"2006","journal-title":"J Clin Endocrinol Metab"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"2433","DOI":"10.1210\/en.2009-1225","article-title":"Progesterone is essential for maintenance and growth of uterine leiomyoma.","volume":"151","author":"H Ishikawa","year":"2010","journal-title":"Endocrinology"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1159\/000292738","article-title":"Proliferative activity of human uterine leiomyoma cells as measured by automatic image analysis.","volume":"34","author":"S Lamminen","year":"1992","journal-title":"Gynecol Obstet Invest"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1016\/S0002-9378(89)80046-8","article-title":"Mitotic activity in uterine leiomyomas during the menstrual cycle.","volume":"160","author":"K Kawaguchi","year":"1989","journal-title":"Am J Obstet Gynecol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1097\/00004347-198506000-00001","article-title":"The effect of progestins on the mitotic activity of uterine fibromyomas.","volume":"4","author":"AJ Tiltman","year":"1985","journal-title":"Int J Gynecol Pathol"},{"key":"ref18","first-page":"513","article-title":"Regression of uterine leiomyomata in response to the antiprogesterone RU 486.","volume":"76","author":"AA Murphy","year":"1993","journal-title":"J Clin Endocrinol Metab"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.1016\/j.fertnstert.2006.11.094","article-title":"A randomized, controlled trial of asoprisnil, a novel selective progesterone receptor modulator, in women with uterine leiomyomata.","volume":"87","author":"K Chwalisz","year":"2007","journal-title":"Fertil Steril"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"2292","DOI":"10.1210\/me.2010-0289","article-title":"Mechanisms of progesterone receptor inhibition of inflammatory responses in cellular models of breast cancer.","volume":"24","author":"S Kobayashi","year":"2010","journal-title":"Mol Endocrinol"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"3577","DOI":"10.1128\/MCB.13.6.3577","article-title":"Growth factor, steroid, and steroid antagonist regulation of cyclin gene expression associated with changes in T-47D human breast cancer cell cycle progression.","volume":"13","author":"EA Musgrove","year":"1993","journal-title":"Mol Cell Biol"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"1866","DOI":"10.1128\/MCB.01060-09","article-title":"Multimodal regulation of E2F1 gene expression by progestins.","volume":"30","author":"HE Wade","year":"2010","journal-title":"Mol Cell Biol"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"9929","DOI":"10.1158\/0008-5472.CAN-07-1103","article-title":"Progestin-dependent progression of human breast tumor xenografts: a novel model for evaluating antitumor therapeutics.","volume":"67","author":"Y Liang","year":"2007","journal-title":"Cancer Res"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1210\/jcem-56-6-1124","article-title":"Antiestrogenic effect of R5020, a synthetic progestin in human breast cancer cells in culture.","volume":"56","author":"F Vignon","year":"1983","journal-title":"J Clin Endocrinol Metab"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"1467","DOI":"10.1126\/science.1130471","article-title":"Prevention of Brca1-mediated mammary tumorigenesis in mice by a progesterone antagonist.","volume":"314","author":"AJ Poole","year":"2006","journal-title":"Science"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1001\/jama.288.3.321","article-title":"Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women&apos;s Health Initiative randomized controlled trial.","volume":"288","author":"JE Rossouw","year":"2002","journal-title":"JAMA"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/S0959-8049(98)00388-8","article-title":"Onapristone, a progesterone receptor antagonist, as first-line therapy in primary breast cancer.","volume":"35","author":"JF Robertson","year":"1999","journal-title":"Eur J Cancer"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"2709","DOI":"10.1200\/JCO.1996.14.10.2709","article-title":"Phase II study of the progesterone antagonist mifepristone in patients with untreated metastatic breast carcinoma: a National Cancer Institute of Canada Clinical Trials Group study.","volume":"14","author":"D Perrault","year":"1996","journal-title":"J Clin Oncol"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/j.mad.2004.04.007","article-title":"A contemporary understanding of progesterone receptor function.","volume":"125","author":"X Li","year":"2004","journal-title":"Mech Ageing Dev"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"1418","DOI":"10.1038\/emboj.2009.88","article-title":"ChIP-Seq of ERalpha and RNA polymerase II defines genes differentially responding to ligands.","volume":"28","author":"WJ Welboren","year":"2009","journal-title":"EMBO J"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"10696","DOI":"10.1074\/jbc.273.17.10696","article-title":"Progesterone regulates transcription of the p21(WAF1) cyclin- dependent kinase inhibitor gene through Sp1 and CBP\/p300.","volume":"273","author":"GI Owen","year":"1998","journal-title":"J Biol Chem"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1186\/1471-2164-12-36","article-title":"Global analysis of estrogen receptor beta binding to breast cancer cell genome reveals an extensive interplay with estrogen receptor alpha for target gene regulation.","volume":"12","author":"OM Grober","year":"2011","journal-title":"BMC Genomics"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"3943","DOI":"10.1128\/MCB.00118-10","article-title":"Genome-wide analysis of estrogen receptor alpha DNA binding and tethering mechanisms identifies Runx1 as a novel tethering factor in receptor-mediated transcriptional activation.","volume":"30","author":"JD Stender","year":"2010","journal-title":"Mol Cell Biol"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"9262","DOI":"10.1016\/S0021-9258(18)98344-4","article-title":"Antagonist-occupied human progesterone receptors bound to DNA are functionally switched to transcriptional agonists by cAMP.","volume":"268","author":"CA Sartorius","year":"1993","journal-title":"J Biol Chem"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"4441","DOI":"10.1073\/pnas.90.10.4441","article-title":"The progesterone antagonist RU486 acquires agonist activity upon stimulation of cAMP signaling pathways.","volume":"90","author":"CA Beck","year":"1993","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1093\/nar\/19.6.1227","article-title":"Two types of antiprogestins identified by their differential action in transcriptionally active extracts from T47D cells.","volume":"19","author":"L Klein-Hitpass","year":"1991","journal-title":"Nucleic Acids Res"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"7879","DOI":"10.1073\/pnas.94.15.7879","article-title":"Steroid receptor induction of gene transcription: a two-step model.","volume":"94","author":"G Jenster","year":"1997","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"12426","DOI":"10.1073\/pnas.231474798","article-title":"Sequential recruitment of steroid receptor coactivator-1 (SRC-1) and p300 enhances progesterone receptor-dependent initiation and reinitiation of transcription from chromatin.","volume":"98","author":"Z Liu","year":"2001","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"2278","DOI":"10.1210\/me.2005-0343","article-title":"Progesterone receptor isoforms A and B differentially regulate MUC1 expression in uterine epithelial cells.","volume":"20","author":"MJ Brayman","year":"2006","journal-title":"Mol Endocrinol"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1379\/CSC-32R.1","article-title":"Intronic hormone response elements mediate regulation of FKBP5 by progestins and glucocorticoids.","volume":"9","author":"TR Hubler","year":"2004","journal-title":"Cell Stress Chaperones"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"D590","DOI":"10.1093\/nar\/gkj144","article-title":"The UCSC Genome Browser Database: update 2006.","volume":"34","author":"AS Hinrichs","year":"2006","journal-title":"Nucleic Acids Res"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1038\/ng1901","article-title":"Genome-wide analysis of estrogen receptor binding sites.","volume":"38","author":"JS Carroll","year":"2006","journal-title":"Nat Genet"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"e87","DOI":"10.1371\/journal.pgen.0030087","article-title":"Whole-genome cartography of estrogen receptor alpha binding sites.","volume":"3","author":"CY Lin","year":"2007","journal-title":"PLoS Genet"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1093\/nar\/gkg108","article-title":"TRANSFAC: transcriptional regulation, from patterns to profiles.","volume":"31","author":"V Matys","year":"2003","journal-title":"Nucleic Acids Res"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"e15188","DOI":"10.1371\/journal.pone.0015188","article-title":"Genome-wide analysis of glucocorticoid receptor binding regions in adipocytes reveal gene network involved in triglyceride homeostasis.","volume":"5","author":"CY Yu","year":"2010","journal-title":"PLoS One"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1016\/j.cell.2008.01.018","article-title":"FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription.","volume":"132","author":"M Lupien","year":"2008","journal-title":"Cell"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"e94","DOI":"10.1371\/journal.pgen.0030094","article-title":"Determinants of cell- and gene-specific transcriptional regulation by the glucocorticoid receptor.","volume":"3","author":"AY So","year":"2007","journal-title":"PLoS Genet"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"W369","DOI":"10.1093\/nar\/gkl198","article-title":"MEME: discovering and analyzing DNA and protein sequence motifs.","volume":"34","author":"TL Bailey","year":"2006","journal-title":"Nucleic Acids Res"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"D102","DOI":"10.1093\/nar\/gkm955","article-title":"JASPAR, the open access database of transcription factor-binding profiles: new content and tools in the 2008 update.","volume":"36","author":"JC Bryne","year":"2008","journal-title":"Nucleic Acids Res"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1128\/MCB.12.2.552","article-title":"The restricted promoter activity of the liver transcription factor hepatocyte nuclear factor 3 beta involves a cell-specific factor and positive autoactivation.","volume":"12","author":"L Pani","year":"1992","journal-title":"Mol Cell Biol"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/0167-4781(94)90066-3","article-title":"Characterization of an Krox-24\/Egr-1-responsive element in the human tumor necrosis factor promoter.","volume":"1219","author":"B Kramer","year":"1994","journal-title":"Biochim Biophys Acta"},{"key":"ref52","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1006\/bbrc.1999.1180","article-title":"ZBP-99 defines a conserved family of transcription factors and regulates ornithine decarboxylase gene expression.","volume":"262","author":"DJ Law","year":"1999","journal-title":"Biochem Biophys Res Commun"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1272\/jnms.71.172","article-title":"Effect of ionizing irradiation on human esophageal cancer cell lines by cDNA microarray gene expression analysis.","volume":"71","author":"H Bo","year":"2004","journal-title":"J Nippon Med Sch"},{"key":"ref54","doi-asserted-by":"crossref","first-page":"1388","DOI":"10.1091\/mbc.E05-08-0708","article-title":"Identification of the junctional plaque protein plakophilin 3 in cytoplasmic particles containing RNA-binding proteins and the recruitment of plakophilins 1 and 3 to stress granules.","volume":"17","author":"I Hofmann","year":"2006","journal-title":"Mol Biol Cell"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1002\/jcp.22063","article-title":"Downregulation of hepatic stellate cell activation by retinol and palmitate mediated by adipose differentiation-related protein (ADRP).","volume":"223","author":"TF Lee","year":"2010","journal-title":"J Cell Physiol"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"3493","DOI":"10.1210\/endo.142.8.8314","article-title":"Regulation of prothymosin alpha gene expression by estrogen in estrogen receptor-containing breast cancer cells via upstream half-palindromic estrogen response element motifs.","volume":"142","author":"PG Martini","year":"2001","journal-title":"Endocrinology"},{"key":"ref57","doi-asserted-by":"crossref","first-page":"2406","DOI":"10.1210\/me.2005-0213","article-title":"The imitation switch protein SNF2L regulates steroidogenic acute regulatory protein expression during terminal differentiation of ovarian granulosa cells.","volume":"20","author":"MA Lazzaro","year":"2006","journal-title":"Mol Endocrinol"},{"key":"ref58","doi-asserted-by":"crossref","first-page":"1984","DOI":"10.1158\/1541-7786.MCR-09-0119","article-title":"Inhibition of expression of the chromatin remodeling gene, SNF2L, selectively leads to DNA damage, growth inhibition, and cancer cell death.","volume":"7","author":"Y Ye","year":"2009","journal-title":"Mol Cancer Res"},{"key":"ref59","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1128\/MCB.26.3.1063-1076.2006","article-title":"Protection against fatty liver but normal adipogenesis in mice lacking adipose differentiation-related protein.","volume":"26","author":"BH Chang","year":"2006","journal-title":"Mol Cell Biol"},{"key":"ref60","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.tem.2011.04.003","article-title":"Determinants of adipophilin function in milk lipid formation and secretion.","volume":"22","author":"BM Chong","year":"2011","journal-title":"Trends Endocrinol Metab"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1158\/1078-0432.CCR-06-1877","article-title":"Expression of adipose differentiation-related protein: a predictor of cancer-specific survival in clear cell renal carcinoma.","volume":"13","author":"M Yao","year":"2007","journal-title":"Clin Cancer Res"},{"key":"ref62","doi-asserted-by":"crossref","first-page":"1866","DOI":"10.1210\/mend-4-12-1866","article-title":"Structural determinants of a glucocorticoid receptor recognition element.","volume":"4","author":"SK Nordeen","year":"1990","journal-title":"Mol Endocrinol"},{"key":"ref63","first-page":"515","article-title":"The constitution of a progesterone response element.","volume":"7","author":"BA Lieberman","year":"1993","journal-title":"Mol Endocrinol"},{"key":"ref64","first-page":"69","article-title":"Hepatocyte nuclear factor-3 alpha promoter regulation involves recognition by cell-specific factors, thyroid transcription factor-1, and autoactivation.","volume":"8","author":"RS Peterson","year":"1997","journal-title":"Cell Growth Differ"},{"key":"ref65","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.cell.2005.05.008","article-title":"Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1.","volume":"122","author":"JS Carroll","year":"2005","journal-title":"Cell"},{"key":"ref66","doi-asserted-by":"crossref","first-page":"17335","DOI":"10.1074\/jbc.C700030200","article-title":"Regulation of GREB1 transcription by estrogen receptor alpha through a multipartite enhancer spread over 20 kb of upstream flanking sequences.","volume":"282","author":"J Deschenes","year":"2007","journal-title":"J Biol Chem"},{"key":"ref67","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1126\/science.1147674","article-title":"DNA oxidation as triggered by H3K9me2 demethylation drives estrogen-induced gene expression.","volume":"319","author":"B Perillo","year":"2008","journal-title":"Science"},{"key":"ref68","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1126\/science.279.5349.349","article-title":"Extension of life-span by introduction of telomerase into normal human cells.","volume":"279","author":"AG Bodnar","year":"1998","journal-title":"Science"},{"key":"ref69","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/j.molcel.2008.02.010","article-title":"Interaction of the glucocorticoid receptor with the chromatin landscape.","volume":"29","author":"S John","year":"2008","journal-title":"Mol Cell"},{"key":"ref70","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1101\/gr.4887606","article-title":"Unbiased location analysis of E2F1-binding sites suggests a widespread role for E2F1 in the human genome.","volume":"16","author":"M Bieda","year":"2006","journal-title":"Genome Res"},{"key":"ref71","doi-asserted-by":"crossref","first-page":"2732","DOI":"10.1128\/MCB.02175-07","article-title":"Genome-wide pattern of TCF7L2\/TCF4 chromatin occupancy in colorectal cancer cells.","volume":"28","author":"P Hatzis","year":"2008","journal-title":"Mol Cell Biol"},{"key":"ref72","first-page":"1716","article-title":"Presence of epidermal growth factor, platelet-derived growth factor, and their receptors in human myometrial tissue and smooth muscle cells: their action in smooth muscle cells in vitro.","volume":"130","author":"MJ Rossi","year":"1992","journal-title":"Endocrinology"},{"key":"ref73","doi-asserted-by":"crossref","first-page":"8918","DOI":"10.1158\/0008-5472.CAN-09-2608","article-title":"Positive cross-talk between estrogen receptor and NF-kappaB in breast cancer.","volume":"69","author":"J Frasor","year":"2009","journal-title":"Cancer Res"},{"key":"ref74","doi-asserted-by":"crossref","first-page":"R137","DOI":"10.1186\/gb-2008-9-9-r137","article-title":"Model-based analysis of ChIP-Seq (MACS).","volume":"9","author":"Y Zhang","year":"2008","journal-title":"Genome Biol"},{"key":"ref75","doi-asserted-by":"crossref","DOI":"10.1109\/BIBMW.2010.5703864","article-title":"bindSDb: A Binding-information Spatial Database.","author":"DFJ Roqueiro","year":"2010"},{"key":"ref76","doi-asserted-by":"crossref","first-page":"3576","DOI":"10.1093\/nar\/gkg585","article-title":"MATCH: A tool for searching transcription factor binding sites in DNA sequences.","volume":"31","author":"AE Kel","year":"2003","journal-title":"Nucleic Acids Res"},{"key":"ref77","doi-asserted-by":"crossref","first-page":"R24","DOI":"10.1186\/gb-2007-8-2-r24","article-title":"Quantifying similarity between motifs.","volume":"8","author":"S Gupta","year":"2007","journal-title":"Genome Biol"},{"key":"ref78","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1530\/JME-10-0064","article-title":"Retinoic acid inhibits endometrial cancer cell growth via multiple genomic mechanisms.","volume":"46","author":"YH Cheng","year":"2011","journal-title":"J Mol Endocrinol"},{"key":"ref79","doi-asserted-by":"crossref","first-page":"e11","DOI":"10.1093\/nar\/gkm1075","article-title":"Model-based variance-stabilizing transformation for Illumina microarray data.","volume":"36","author":"SM Lin","year":"2008","journal-title":"Nucleic Acids Res"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0029021","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,17]],"date-time":"2024-04-17T23:03:46Z","timestamp":1713395026000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0029021"}},"subtitle":[],"editor":[{"given":"Masaru","family":"Katoh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2012,1,17]]},"references-count":79,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2012,1,17]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0029021","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,1,17]]}}}