{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,15]],"date-time":"2026-02-15T21:20:06Z","timestamp":1771190406051,"version":"3.50.1"},"reference-count":36,"publisher":"Public Library of Science (PLoS)","issue":"1","license":[{"start":{"date-parts":[[2012,1,24]],"date-time":"2012-01-24T00:00:00Z","timestamp":1327363200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0030599","type":"journal-article","created":{"date-parts":[[2012,1,24]],"date-time":"2012-01-24T22:02:04Z","timestamp":1327442524000},"page":"e30599","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":59,"title":["Diabetes Is the Main Factor Accounting for Hypomagnesemia in Obese Subjects"],"prefix":"10.1371","volume":"7","author":[{"given":"Albert","family":"Lecube","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan Antonio","family":"Baena-Fustegueras","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Manuel","family":"Fort","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dolors","family":"Pelegr\u00ed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina","family":"Hern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafael","family":"Sim\u00f3","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2012,1,24]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"2151","DOI":"10.1001\/archinte.159.18.2151","article-title":"Serum and dietary magnesium and the risk for type 2 diabetes mellitus: the Atherosclerosis Risk in Communities Study.","volume":"159","author":"WH Kao","year":"1999","journal-title":"Arch Intern Med"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.2337\/diacare.26.4.1147","article-title":"Oral magnesium supplementation improves insulin sensitivity and metabolic control in type 2 diabetic subjects. A randomized double-blind controlled trial.","volume":"26","author":"M Rodr\u00edguez-Moran","year":"2003","journal-title":"Diabetes Care"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"134","DOI":"10.2337\/diacare.27.1.134","article-title":"Magnesium intake and risk of type 2 diabetes in men and women.","volume":"27","author":"R Lopez-Ridaura","year":"2004","journal-title":"Diabetes Care"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1016\/j.clnu.2006.03.003","article-title":"Magnesium and diabetes mellitus: their relationship.","volume":"25","author":"CH Sales","year":"2006","journal-title":"Clin Nutr"},{"key":"ref5","first-page":"169","article-title":"Relationship between hypomagnesemia and glucose homeostasis.","volume":"2008; 54","author":"M Montagnana","year":"2008","journal-title":"Clin Lab"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"188","DOI":"10.2337\/diacare.18.2.188","article-title":"Hypomagnesemia in type II diabetes: effects of a 3 month replacement therapy.","volume":"18","author":"N Eibl","year":"1995","journal-title":"Diabetes Care"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.abb.2006.05.007","article-title":"Magnesium metabolism in type 2 diabetes mellitus, metabolic syndrome and insulin resistance.","volume":"458","author":"M Barbagallo","year":"2007","journal-title":"Arch Biochem Biophys"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1159\/000013582","article-title":"Serum ionized magnesium levels in type 2 diabetic patients with microalbuminuria or clinical proteinuria.","volume":"20","author":"A Corsonello","year":"2000","journal-title":"Am J Nephrol"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1080\/07315724.2006.10719534","article-title":"Serum ionized magnesium levels in relation to metabolic syndrome in type 2 diabetic patients.","volume":"25","author":"F Corica","year":"2006","journal-title":"J Am Coll Nutr"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"366","DOI":"10.2215\/CJN.02960906","article-title":"Hypomagnesemia in patients with type 2 diabetes.","volume":"2","author":"PC Pham","year":"2007","journal-title":"Clin J Am Soc Nephrol"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1038\/sj.ejcn.1602568","article-title":"Associations of serum minerals with body mass index in adult women.","volume":"61","author":"CH Song","year":"2007","journal-title":"Eur J Clin Nutr"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"1724","DOI":"10.1001\/jama.292.14.1724","article-title":"Bariatric surgery: a systematic review and meta-analysis.","volume":"292","author":"H Buchwald","year":"2004","journal-title":"JAMA"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1016\/S0140-6736(07)61602-X","article-title":"The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies.","volume":"370","author":"E von Elm","year":"2007","journal-title":"Lancet"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1007\/s11695-008-9536-5","article-title":"Serum magnesium status after gastric bypass surgery in obesity.","volume":"19","author":"HE Johansson","year":"2009","journal-title":"Obes Surg"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"1616","DOI":"10.1681\/ASN.V1071616","article-title":"Hypomagnesemia.","volume":"10","author":"ZS Agus","year":"1999","journal-title":"J Am Soc Nephrol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1023\/A:1022950321817","article-title":"Hypomagnesemia and hypermagnesemia.","volume":"4","author":"JM Topf","year":"2003","journal-title":"Rev Endocr Metab Disord"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1042\/cs0580255","article-title":"Effect of a natural and artificial menopause on serum, urinary and erythrocyte magnesium.","volume":"58","author":"R Lindsay","year":"1980","journal-title":"Clin Sci (Lond)"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1016\/S0015-0282(99)00065-5","article-title":"Serum ionized magnesium and calcium in women after menopause: inverse relation of estrogen with ionized magnesium.","volume":"71","author":"O Muneyyirci-Delale","year":"1999","journal-title":"Fertil Steril"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.cca.2009.08.007","article-title":"Genetic determinants of extracellular magnesium concentration: analysis of multiple candidate genes, and evidence for association with the strogen receptor alpha (ESR1) locus.","volume":"409","author":"AY Shuen","year":"2009","journal-title":"Clin Chim Acta"},{"key":"ref20","article-title":"Magnesium and anabolic hormones in older men.","author":"M Maggio","year":"2011","journal-title":"Int J Androl"},{"key":"ref21","first-page":"306","article-title":"Genetic regulation of blood and tissue magnesium content in mammals.","volume":"7","author":"JG Henrotte","year":"1988","journal-title":"Magnesium"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1111\/j.1365-2362.1982.tb00942.x","article-title":"Renal hypomagnesaemia in human diabetes mellitus: its relation to glucose homeostasis.","volume":"12","author":"P McNair","year":"1982","journal-title":"Eur J Clin Invest"},{"key":"ref23","first-page":"125","article-title":"Nutrition and magnesium absorption: a review.","volume":"16","author":"EJ Brink","year":"1992","journal-title":"Prog Food Nutr Sci"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1001\/archinte.167.9.956","article-title":"Fiber and magnesium intake and incidence of type 2 diabetes: a prospective study and meta-analysis.","volume":"167","author":"MB Schulze","year":"2007","journal-title":"Arch Intern Med"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1007\/BF00869264","article-title":"Insulin induces opposite changes in plasma and erithrocyte magnesium concentrations in normal man.","volume":"29","author":"G Paolisso","year":"1986","journal-title":"Diabetologia"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1016\/0895-4356(94)00200-A","article-title":"Associations of serum and dietary magnesium with cardiovascular disease, hypertension, diabetes, insulin, and carotid arterial wall thickness: the ARIC study. Atherosclerosis Risk in Communities Study.","volume":"48","author":"J Ma","year":"1995","journal-title":"J Clin Epidemiol"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1002\/dmrr.644","article-title":"Hypomagnesemia, oxidative stress, inflammation, and metabolic syndrome.","volume":"22","author":"F Guerrero-Romero","year":"2006","journal-title":"Diabetes Metab Res Rev"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"429","DOI":"10.5414\/CNP63429","article-title":"Lower serum magnesium levels are associated with more rapid decline of renal function in patients with diabetes mellitus type 2.","volume":"63","author":"PC Pham","year":"2005","journal-title":"Clin Nephrol"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"396","DOI":"10.2337\/diab.36.3.396","article-title":"Does a common mechanism induce the diverse complications of diabetes?","volume":"36","author":"AI Winegard","year":"1987","journal-title":"Diabetes"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1007\/s00592-007-0254-6","article-title":"Prediction of all-cause mortality in a patient population with hypertension and type 2 DM by using traditional risk factors and serum-phosphate, -calcium and \u2013magnesium.","volume":"44","author":"L Haglin","year":"2007","journal-title":"Acta Diabetol"},{"key":"ref31","first-page":"126","article-title":"Intracellular magnesium and insulin resistance.","volume":"17","author":"J Takaya","year":"2004","journal-title":"Magnes Res"},{"key":"ref32","first-page":"189","article-title":"Elevated concentrations of TNF-alpha are related to low serum magnesium levels in obese subjects.","volume":"17","author":"M Rodriguez-Moran","year":"2004","journal-title":"Magnes Res"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1111\/j.1365-2796.2007.01840.x","article-title":"Magnesium intake and risk of type 2 diabetes: a meta-analysis.","volume":"262","author":"SC Larsson","year":"2007","journal-title":"J Intern Med"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1080\/00365519950185229","article-title":"Current databases on biological variation: pros, cons and progress.","volume":"59","author":"C Ric\u00f3s","year":"1999","journal-title":"Scand J Clin Lab Invest"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/S0889-8529(18)30035-5","article-title":"Disorders of magnesium metabolism.","volume":"24","author":"J Nadler","year":"1995","journal-title":"Endocrinol Metab Clin North Am"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1080\/07315724.1989.10720330","article-title":"determination of intracellular free magnesium by nuclear magnetic resonance in human magnesium deficiency.","volume":"8","author":"E Ryzen","year":"1989","journal-title":"J Am Coll Nutr"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0030599","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,26]],"date-time":"2021-12-26T22:20:30Z","timestamp":1640557230000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0030599"}},"subtitle":[],"editor":[{"given":"Massimo","family":"Federici","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2012,1,24]]},"references-count":36,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2012,1,24]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0030599","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,1,24]]}}}