{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T06:59:52Z","timestamp":1791356392007,"version":"4.3.1"},"reference-count":62,"publisher":"Public Library of Science (PLoS)","issue":"1","license":[{"start":{"date-parts":[[2012,1,26]],"date-time":"2012-01-26T00:00:00Z","timestamp":1327536000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0030692","type":"journal-article","created":{"date-parts":[[2012,1,26]],"date-time":"2012-01-26T21:51:53Z","timestamp":1327614713000},"page":"e30692","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":109,"title":["Detection of Wolbachia in the Tick Ixodes ricinus is Due to the Presence of the Hymenoptera Endoparasitoid Ixodiphagus hookeri"],"prefix":"10.1371","volume":"7","author":[{"given":"Olivier","family":"Plantard","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agn\u00e8s","family":"Bouju-Albert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Astrid","family":"Malard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Axelle","family":"Hermouet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilles","family":"Capron","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00e9l\u00e8ne","family":"Verheyden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2012,1,26]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1086\/319347","article-title":"Ticks and tickborne bacterial diseases in humans: An emerging infectious threat.","volume":"32","author":"P Parola","year":"2001","journal-title":"Clinical Infectious Diseases"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1017\/S0031182004005967","article-title":"The global importance of ticks.","volume":"129","author":"F Jongejan","year":"2004","journal-title":"Parasitology"},{"key":"ref3","article-title":"Biology of ticks:","author":"DE Sonenshine","year":"1991"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"S37","DOI":"10.1017\/S0031182004004925","article-title":"Tick ecology: processes and patterns behind the epidemiological risk posed by ixodid ticks as vectors.","volume":"129","author":"SE Randolph","year":"2004","journal-title":"Parasitology"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"719-+","DOI":"10.1128\/CMR.18.4.719-756.2005","article-title":"Tick-borne rickettsioses around the world: Emerging diseases challenging old concepts.","volume":"18","author":"P Parola","year":"2005","journal-title":"Clinical Microbiology Reviews"},{"key":"ref6","doi-asserted-by":"crossref","DOI":"10.1186\/1741-7007-7-6","article-title":"Evolution and diversity of <italic>Rickettsia<\/italic> bacteria.","volume":"7","author":"LA Weinert","year":"2009","journal-title":"Bmc Biology"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"4371","DOI":"10.1111\/j.1365-294X.2008.03914.x","article-title":"Microbial communities and interactions in the lone star tick, <italic>Amblyomma americanum<\/italic>.","volume":"17","author":"K Clay","year":"2008","journal-title":"Mol Ecol"},{"key":"ref8","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0000405","article-title":"Antibiotic Treatment of the Tick Vector <italic>Amblyomma americanum<\/italic> Reduced Reproductive Fitness.","volume":"2","author":"JM Zhong","year":"2007","journal-title":"Plos One"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1111\/j.1462-2920.2006.01024.x","article-title":"Widespread distribution and high prevalence of an alpha-proteobacterial symbiont in the tick <italic>Ixodes ricinus<\/italic>.","volume":"8","author":"N Lo","year":"2006","journal-title":"Environmental Microbiology"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1017\/S0031182007004052","article-title":"<italic>Midichloria mitochondrii<\/italic> is widespread in hard ticks (Ixodidae) and resides in the mitochondria of phylogenetically diverse species.","volume":"135","author":"S Epis","year":"2008","journal-title":"Parasitology"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"2535","DOI":"10.1099\/ijs.0.64386-0","article-title":"\u2018Candidatus <italic>Midichloria mitochondrii\u2019<\/italic>, an endosymbiont of the tick <italic>Ixodes ricinus<\/italic> with a unique intramitochondrial lifestyle.","volume":"56","author":"D Sassera","year":"2006","journal-title":"Int J Syst Evol Microbiol"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.tice.2003.08.004","article-title":"A symbiont of the tick <italic>Ixodes ricinus<\/italic> invades and consumes mitochondria in a mode similar to that of the parasitic bacterium <italic>Bdellovibrio bacteriovorus<\/italic>.","volume":"36","author":"L Sacchi","year":"2004","journal-title":"Tissue & Cell"},{"key":"ref13","doi-asserted-by":"crossref","DOI":"10.1093\/molbev\/msr159","article-title":"Phylogenomic evidence for the presence of a flagellum and cbb3 oxidase in the free-living mitochondrial ancestor.","author":"D Sassera","year":"2011"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"e11478","DOI":"10.1371\/journal.pone.0011478","article-title":"A Novel Obligate Intracellular Gamma-Proteobacterium Associated with Ixodid Ticks <italic>Diplorickettsia massiliensis<\/italic>, Gen. Nov., Sp. Nov.","volume":"5","author":"O Mediannikov","year":"2010","journal-title":"PLoS ONE"},{"key":"ref15","doi-asserted-by":"crossref","DOI":"10.1186\/1471-2180-11-6","article-title":"Assessment of bacterial diversity in the cattle tick <italic>Rhipicephalus<\/italic> (<italic>Boophilus<\/italic>) <italic>microplus<\/italic> through tag-encoded pyrosequencing.","volume":"11","author":"R Andreotti","year":"2011","journal-title":"Bmc Microbiology"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"e25604","DOI":"10.1371\/journal.pone.0025604","article-title":"Metagenomic Profile of the Bacterial Communities Associated with <italic>Ixodes ricinus<\/italic> Ticks.","volume":"6","author":"G Carpi","year":"2011","journal-title":"PLoS ONE"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1126\/science.1190333","article-title":"Species Interactions in a Parasite Community Drive Infection Risk in a Wildlife Population.","volume":"330","author":"S Telfer","year":"2010","journal-title":"Science"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"e7","DOI":"10.1371\/journal.ppat.0040007","article-title":"Competitive exclusion between piroplasmosis and anaplasmosis agents within cattle.","volume":"4","author":"L Dib","year":"2008","journal-title":"PLoS Pathog"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"12168","DOI":"10.1073\/pnas.1003379107","article-title":"Genome sequences of the human body louse and its primary endosymbiont provide insights into the permanent parasitic lifestyle.","volume":"107","author":"EF Kirkness","year":"2010","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1073\/pnas.0911476107","article-title":"<italic>Wolbachia<\/italic> as a bacteriocyte-associated nutritional mutualist.","volume":"107","author":"T Hosokawa","year":"2010","journal-title":"Proceedings of the National Academy of Sciences"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1126\/science.1201618","article-title":"Natural Microbe-Mediated Refractoriness to <italic>Plasmodium<\/italic> Infection in <italic>Anopheles gambiae<\/italic>.","volume":"332","author":"CM Cirimotich","year":"2011","journal-title":"Science"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"1953","DOI":"10.1111\/j.1365-294X.2010.04606.x","article-title":"<italic>Wolbachia<\/italic> modulates Chikungunya replication in <italic>Aedes albopictus<\/italic>.","volume":"19","author":"L Mousson","year":"2010","journal-title":"Molecular Ecology"},{"key":"ref23","article-title":"The endosymbiotic bacterium <italic>Wolbachia<\/italic> induces resistance to dengue virus in <italic>Aedes aegypti<\/italic>.","author":"GW Bian","year":"2010"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1126\/science.1162418","article-title":"<italic>Wolbachia<\/italic> and Virus Protection in Insects.","volume":"322","author":"LM Hedges","year":"2008","journal-title":"Science"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1146\/annurev.ento.42.1.587","article-title":"Biology of <italic>Wolbachia<\/italic>.","volume":"42","author":"JH Werren","year":"1997","journal-title":"Annual Review of Entomology"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1038\/hdy.2009.160","article-title":"Phylogeography of <italic>Nasonia vitripennis<\/italic> (Hymenoptera) indicates a mitochondrial-<italic>Wolbachia<\/italic> sweep in North America.","volume":"104","author":"R Raychoudhury","year":"2010","journal-title":"Heredity"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1534\/genetics.106.060921","article-title":"The Impact of Male-Killing Bacteria on Host Evolutionary Processes.","volume":"175","author":"J Engelst\u00e4dter","year":"2007","journal-title":"Genetics"},{"key":"ref28","doi-asserted-by":"crossref","DOI":"10.1089\/vbz.2010.0103","article-title":"Questing Ticks in Suburban Forest Are Infected by at Least Six Tick-Borne Pathogens.","volume":"11","author":"C Reis","year":"2011","journal-title":"Vector-Borne and Zoonotic Diseases"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1186\/1741-7007-6-27","article-title":"The diversity of reproductive parasites among arthropods: <italic>Wolbachia<\/italic> do not walk alone.","volume":"6","author":"O Duron","year":"2008","journal-title":"BMC Biol"},{"key":"ref30","first-page":"656","article-title":"Egg laying of <italic>Ixodiphagus caucurtei<\/italic> Du Buysson in larval ticks.","volume":"68","author":"RA Cooley","year":"1919","journal-title":"Science"},{"key":"ref31","first-page":"1085","article-title":"Parasitisme latent de l\u2032<italic>Ixodiphagus caucurtei<\/italic> chez les larves gorg\u00e9es et les nymphes \u00e0 jeun de divers ixodines (<italic>Ixodes ricinus<\/italic> et <italic>Rhipicephalus sanguineus<\/italic>).","volume":"191","author":"E Brumpt","year":"1930","journal-title":"Comptes Rendus de l\u2032Acad\u00e9mie des Sciences de Paris"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1093\/molbev\/msj049","article-title":"Widespread Recombination Throughout <italic>Wolbachia<\/italic> Genomes.","volume":"23","author":"L Baldo","year":"2006","journal-title":"Molecular Biology and Evolution"},{"key":"ref33","first-page":"86","article-title":"Pathogens and symbionts in ticks: prevalence of <italic>Anaplasma phagocytophilum<\/italic> (<italic>Ehrlichia<\/italic> sp.), <italic>Wolbachia<\/italic> sp., <italic>Rickettsia<\/italic> sp., and <italic>Babesia<\/italic> sp. in Southern Germany.","volume":"293","author":"K Hartelt","year":"2004","journal-title":"Int J Med Microbiol"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1111\/j.1574-6941.2008.00468.x","article-title":"Diversity of <italic>Ixodes ricinus<\/italic> tick-associated bacterial communities from different forests.","volume":"66","author":"L van Overbeek","year":"2008","journal-title":"Fems Microbiology Ecology"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1128\/JCM.43.3.1127-1132.2005","article-title":"Detection and Identification of <italic>Ehrlichia<\/italic> spp. in Ticks Collected in Tunisia and Morocco.","volume":"43","author":"MH Sarih","year":"2005","journal-title":"J Clin Microbiol"},{"key":"ref36","first-page":"1362","article-title":"A review on the use of <italic>Ixodiphagus<\/italic> wasps (Hymenoptera: Encyrtidae) as natural enemies for the control of ticks (Acari: Ixodidae).","volume":"3","author":"R Hu","year":"1998","journal-title":"Systematic and Applied Acarology"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1093\/jee\/4.5.425","article-title":"Notes on the life history of the tick parasite <italic>Hunterellus hookeri<\/italic> Howard.","volume":"4","author":"HP Wood","year":"1911","journal-title":"Journal of Economic Entomology"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"3933","DOI":"10.1128\/AEM.63.10.3933-3940.1997","article-title":"Characterization of an endosymbiont infecting wood ticks, <italic>Dermacentor andersoni<\/italic>, as a member of the genus <italic>Francisella<\/italic>.","volume":"63","author":"ML Niebylski","year":"1997","journal-title":"Applied and Environmental Microbiology"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1093\/jmedent\/35.6.1050","article-title":"Effects of the feeding process of <italic>Ixodes scapularis<\/italic> (Acari : Ixodidae) on embryonic development of its parasitoid, <italic>Ixodiphagus hookeri<\/italic> (Hymenoptera : Encyrtidae).","volume":"35","author":"RJ Hu","year":"1998","journal-title":"Journal of Medical Entomology"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1111\/j.1439-0418.2010.01560.x","article-title":"A hidden beneficial: biology of the tick-wasp <italic>Ixodiphagus hookeri<\/italic> in Germany.","volume":"135","author":"J Collatz","year":"2011","journal-title":"Journal of Applied Entomology"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1093\/genetics\/135.2.565","article-title":"Cytoplasmic Incompatibility and Bacterial Density in <italic>Nasonia vitripennis<\/italic>.","volume":"135","author":"JAJ Breeuwer","year":"1993","journal-title":"Genetics"},{"key":"ref42","first-page":"359","article-title":"Utilisation des insectes auxiliaires \u2013 Entomophages dans la lutte contre les insectes pathogenes.","volume":"36","author":"ME Brumpt","year":"1913","journal-title":"La Presse Medicale"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1603\/0022-2585-40.5.642","article-title":"Reduced abundance of <italic>Ixodes scapularis<\/italic> (Acari : Ixodidae) and the tick parasitoid <italic>Ixodiphagus hookeri<\/italic> (Hymenoptera : Encyrtidae) with reduction of white-tailed deer.","volume":"40","author":"KC Stafford","year":"2003","journal-title":"Journal of Medical Entomology"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1098\/rspb.2007.1211","article-title":"Symbiont-mediated protection.","volume":"275","author":"ER Haine","year":"2008","journal-title":"Proceedings of the Royal Society B-Biological Sciences"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"3926","DOI":"10.1128\/AEM.63.10.3926-3932.1997","article-title":"Endosymbionts of ticks and their relationship to <italic>Wolbachia<\/italic> spp. and tick-borne pathogens of humans and animals.","volume":"63","author":"H Noda","year":"1997","journal-title":"Applied and Environmental Microbiology"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1128\/AEM.70.1.616-620.2004","article-title":"Intracellular symbionts and other bacteria associated with deer ticks (<italic>Ixodes scapularis<\/italic>) from Nantucket and Wellfleet, Cape Cod, Massachusetts.","volume":"70","author":"MJ Benson","year":"2004","journal-title":"Applied and Environmental Microbiology"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1111\/j.1462-2920.2005.00955.x","article-title":"Molecular analysis of microbial communities identified in different developmental stages of <italic>Ixodes scapularis<\/italic> ticks from Westchester and Dutchess Counties, New York.","volume":"8","author":"CX Moreno","year":"2006","journal-title":"Environmental Microbiology"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"1753","DOI":"10.1126\/science.1142490","article-title":"Widespread lateral gene transfer from intracellular bacteria to multicellular eukaryotes.","volume":"317","author":"JC Hotopp","year":"2007","journal-title":"Science"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"2211","DOI":"10.1099\/mic.0.027581-0","article-title":"Extensive genomic diversity of closely related <italic>Wolbachia<\/italic> strains.","volume":"155","author":"N Ishmael","year":"2009","journal-title":"Microbiology"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/j.1365-2915.1987.tb00317.x","article-title":"Absence of spirochaetes (<italic>Borrelia burgdorferi<\/italic>) and piroplasms (<italic>Babesia microti<\/italic>) in deer ticks (<italic>Ixodes dammini<\/italic>) parasitized by chalcid wasps (<italic>Hunterellus hookeri<\/italic>).","volume":"1","author":"TN Mather","year":"1987","journal-title":"Medical and Veterinary Entomology"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1017\/S0031182006001545","article-title":"Transstadial and transovarial persistence of <italic>Babesia divergens<\/italic> DNA in <italic>Ixodes ricinus<\/italic> ticks fed on infected blood in a new skin-feeding technique.","volume":"134","author":"S Bonnet","year":"2007","journal-title":"Parasitology"},{"key":"ref52","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1080\/03014223.2010.482973","article-title":"A new species of <italic>Ixodiphagus<\/italic> (Hymenoptera: Chalcidoidea: Encyrtidae) parasitizing seabird ticks in New Zealand.","volume":"37","author":"ACG Heath","year":"2010","journal-title":"New Zealand Journal of Zoology"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1098\/rstb.1992.0079","article-title":"Insect Parasitoids: An Evolutionary Overview.","volume":"337","author":"P Eggleton","year":"1992","journal-title":"Philosophical Transactions of the Royal Society of London Series B: Biological Sciences"},{"key":"ref54","doi-asserted-by":"crossref","first-page":"489","DOI":"10.2307\/2422494","article-title":"Morphology of two chalcidoid parasites of ticks, <italic>Hunterellus hookeri<\/italic> Howard, 1908, and <italic>Ixodiphagus texanus<\/italic> Howard, 1907.","volume":"59","author":"MS Quaraishi","year":"1958","journal-title":"The American Midland Naturalist"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"2373","DOI":"10.1128\/JB.180.9.2373-2378.1998","article-title":"Cloning and Characterization of a Gene Encoding the Major Surface Protein of the Bacterial Endosymbiont <italic>Wolbachia pipientis<\/italic>.","volume":"180","author":"HR Braig","year":"1998","journal-title":"J Bacteriol"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1098\/rspb.1995.0117","article-title":"Evolution and Phylogeny of <italic>Wolbachia<\/italic> - reproductive parasites of arthropods.","volume":"261","author":"JH Werren","year":"1995","journal-title":"Proceedings of the Royal Society of London Series B-Biological Sciences"},{"key":"ref57","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1046\/j.1365-294X.2003.01725.x","article-title":"Tracing the geographical origin of <italic>Megastigmus transvaalensis<\/italic> (Hymenoptera : Torymidae): an African wasp feeding on a South American plant in North America.","volume":"12","author":"SJ Scheffer","year":"2003","journal-title":"Molecular Ecology"},{"key":"ref58","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.ijpara.2003.10.004","article-title":"Mapping the presence of <italic>Wolbachia pipientis<\/italic> on the phylogeny of filarial nematodes: evidence for symbiont loss during evolution.","volume":"34","author":"M Casiraghi","year":"2004","journal-title":"International Journal for Parasitology"},{"key":"ref59","doi-asserted-by":"crossref","first-page":"W695","DOI":"10.1093\/nar\/gkq313","article-title":"A new bioinformatics analysis tools framework at EMBL-EBI.","volume":"38","author":"M Goujon","year":"2010","journal-title":"Nucleic Acids Research"},{"key":"ref60","doi-asserted-by":"crossref","DOI":"10.1093\/molbev\/msr121","article-title":"MEGA5: Molecular Evolutionary Genetics Analysis using Maximum Likelihood, Evolutionary Distance, and Maximum Parsimony Methods.","author":"K Tamura","year":"2011"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"11030","DOI":"10.1073\/pnas.0404206101","article-title":"Prospects for inferring very large phylogenies by using the neighbor-joining method.","volume":"101","author":"K Tamura","year":"2004","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"ref62","doi-asserted-by":"crossref","first-page":"4219","DOI":"10.1128\/JCM.38.11.4219-4221.2000","article-title":"Detection of <italic>Ehrlichia platys<\/italic> DNA in brown dog ticks (<italic>Rhipicephalus sanguineus<\/italic>) in Okinawa Island, Japan.","volume":"38","author":"H Inokuma","year":"2000","journal-title":"Journal of Clinical Microbiology"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0030692","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,27]],"date-time":"2021-12-27T02:26:55Z","timestamp":1640572015000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0030692"}},"subtitle":[],"editor":[{"given":"J. Stephen","family":"Dumler","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2012,1,26]]},"references-count":62,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2012,1,26]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0030692","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,1,26]]}}}