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Li","year":"2009","journal-title":"Bioinformatics"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1038\/nmeth.1226","article-title":"Mapping and quantifying mammalian transcriptomes by RNA-seq.","volume":"5","author":"A Mortazavi","year":"2008","journal-title":"Nat Methods"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.1126\/science.1123287","article-title":"Genome-wide prediction of <italic>C. elegans<\/italic> genetic interactions.","volume":"311","author":"W Zhong","year":"2006","journal-title":"Science"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"R41","DOI":"10.1186\/gb-2010-11-4-r41","article-title":"Improving draft assemblies by iterative mapping and assemblies of short reads to eliminate gaps.","volume":"11","author":"IJ Tsai","year":"2010","journal-title":"Genome Biol"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1242\/jcs.115.4.827","article-title":"Identification and 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Biol"},{"key":"ref52","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1016\/S0020-7519(03)00111-5","article-title":"Molecular characterisation of the <italic>Ancylostoma<\/italic>-secreted protein family from the adult stage of <italic>Ancylostoma caninum<\/italic>.","volume":"33","author":"B Zhan","year":"2003","journal-title":"Int J Parasitol"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"e326","DOI":"10.1371\/journal.pntd.0000326","article-title":"Stage- and gender-specific proteomic analysis of <italic>Brugia malayi<\/italic> excretory-secretory products.","volume":"2","author":"Y Moreno","year":"2008","journal-title":"PLoS Negl Trop Dis"},{"key":"ref54","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1074\/mcp.M800206-MCP200","article-title":"Proteomics analysis of the excretory\/secretory component of the blood-feeding stage of the hookworm, <italic>Ancylostoma caninum<\/italic>.","volume":"8","author":"J Mulvenna","year":"2009","journal-title":"Mol Cell Proteomics"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"1573","DOI":"10.1016\/j.jprot.2011.06.002","article-title":"Proteomic analysis of secretory products from the model gastrointestinal nematode <italic>Heligmosomoides polygyrus<\/italic> reveals dominance of Venom Allergen-Like (VAL).","volume":"74","author":"JP Hewitson","year":"2011","journal-title":"J Proteomics"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1007\/s00436-010-1817-y","article-title":"Expression and immune response analysis of <italic>Schistosoma japonicum<\/italic> VAL-1, a homologue of vespid venom allergens.","volume":"106","author":"J Chen","year":"2010","journal-title":"Parasitol Res"},{"key":"ref57","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.molbiopara.2007.06.002","article-title":"Proteomic analysis of <italic>Schisosoma mansoni<\/italic> egg secretions.","volume":"155","author":"CL Cass","year":"2007","journal-title":"Mol Biochem Parasitol"},{"key":"ref58","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1002\/pmic.200900393","article-title":"The secreted and surface proteomes of the adult stage of the carcinogenic human liver fluke <italic>Opisthorchis viverrini<\/italic>.","volume":"10","author":"J Mulvenna","year":"2010","journal-title":"Proteomics"},{"key":"ref59","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.molbiopara.2008.11.005","article-title":"Proteomic analysis of <italic>Schistosoma mansoni<\/italic> proteins released during in vitro miracidium-to-sporocyst transformation.","volume":"164","author":"XJ Wu","year":"2009","journal-title":"Mol Biochem Parasitol"},{"key":"ref60","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1074\/mcp.M500313-MCP200","article-title":"Identification of novel proteases and immunomodulators in the secretions of schistosome cercariae that facilitate host entry.","volume":"5","author":"RS 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Osman","year":"2011","journal-title":"Biotechnol Adv"},{"key":"ref64","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1126\/science.1058040","article-title":"The sequence of the human genome.","volume":"291","author":"JC Venter","year":"2001","journal-title":"Science"},{"key":"ref65","doi-asserted-by":"crossref","first-page":"8725","DOI":"10.1073\/pnas.1104695108","article-title":"Measuring the evolutionary rate of protein-protein interaction.","volume":"108","author":"W Qian","year":"2011","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref66","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1210\/er.2008-0032","article-title":"The CAP Superfamily: Cysteine-Rich Secretory Proteins, Antigen 5, and Pathogenesis-Related 1 Proteins \u2013 Roles in Reproduction, Cancer, and Immune Defence.","volume":"29","author":"GM Gibbs","year":"2008","journal-title":"Endocr 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Helminthol"},{"key":"ref70","article-title":"Fasciolosis.","year":"1999"},{"key":"ref71","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1016\/S0020-7519(03)00158-9","article-title":"Progress in the development of a recombinant vaccine for human hookworm disease: the Human Hookworm Vaccine Initiative.","volume":"33","author":"PJ Hotez","year":"2003","journal-title":"Int J Parasitol"},{"key":"ref72","doi-asserted-by":"crossref","first-page":"e469","DOI":"10.1371\/journal.pntd.0000469","article-title":"Tissue specific profiling of females of <italic>Schistosoma japonicum<\/italic> by integrated laser microdissection microscopy and microarray analysis.","volume":"3","author":"GN Gobert","year":"2009","journal-title":"PLoS Negl Trop Dis"},{"key":"ref73","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/S0378-1119(96)00431-3","article-title":"RTVP-1, a novel human gene with sequence similarity to genes of diverse species, is expressed in tumor cell lines of glial 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