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living cells.","volume":"283","author":"I Drago","year":"2008","journal-title":"J Biol Chem"},{"key":"ref88","doi-asserted-by":"crossref","first-page":"1683","DOI":"10.1242\/jcs.110.15.1683","article-title":"Cell-type specific calcium signalling in a Drosophila epithelium.","volume":"15)","author":"P Rosay","year":"1997","journal-title":"J Cell Sci 110 ( Pt"},{"key":"ref89","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1152\/physiolgenomics.00038.2006","article-title":"Novel subcellular locations and functions for secretory pathway Ca2+\/Mn2+-ATPases.","volume":"26","author":"TD Southall","year":"2006","journal-title":"Physiol Genomics"},{"key":"ref90","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1091\/mbc.7.3.419","article-title":"Aequorin targeted to the endoplasmic reticulum reveals heterogeneity in luminal Ca++ concentration and reports agonist- or IP3-induced release of Ca++.","volume":"7","author":"D Button","year":"1996","journal-title":"Mol Biol Cell"},{"key":"ref91","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1242\/jeb.197.1.421","article-title":"The malpighian tubules of Drosophila melanogaster: a novel phenotype for studies of fluid secretion and its control.","volume":"197","author":"JA Dow","year":"1994","journal-title":"J Exp Biol"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0032577","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,22]],"date-time":"2024-04-22T20:21:48Z","timestamp":1713817308000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0032577"}},"subtitle":[],"editor":[{"given":"Shree 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