{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T14:11:42Z","timestamp":1777385502105,"version":"3.51.4"},"reference-count":38,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2012,4,16]],"date-time":"2012-04-16T00:00:00Z","timestamp":1334534400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0034851","type":"journal-article","created":{"date-parts":[[2012,4,16]],"date-time":"2012-04-16T20:54:27Z","timestamp":1334609667000},"page":"e34851","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":111,"title":["Maternal Perception of Reduced Fetal Movements Is Associated with Altered Placental Structure and Function"],"prefix":"10.1371","volume":"7","author":[{"given":"Lynne K.","family":"Warrander","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gauri","family":"Batra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanna","family":"Bernatavicius","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan L.","family":"Greenwood","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip","family":"Dutton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebecca L.","family":"Jones","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Colin P.","family":"Sibley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander E. P.","family":"Heazell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2012,4,16]]},"reference":[{"key":"ref1","article-title":"3rd Annual Report","year":"1995"},{"key":"ref2","article-title":"Perinatal Mortality 2008","year":"2010"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"S5","DOI":"10.1186\/1471-2393-9-S1-S5","article-title":"Reducing stillbirths: screening and monitoring during pregnancy and labour.","volume":"9","author":"RA Haws","year":"2009","journal-title":"BMC Pregnancy Childbirth"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1136\/bmj.1.6021.1305","article-title":"Fetal activity and fetal wellbeing: an evaluation.","volume":"1","author":"JF Pearson","year":"1976","journal-title":"Br Med J"},{"key":"ref5","first-page":"53","article-title":"Case-control study of factors associated with intrauterine deaths.","volume":"6","author":"S Efkarpidis","year":"2004","journal-title":"Med Ged Med"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1067\/mob.2001.110697","article-title":"Risk factors for sudden intrauterine unexplained death: epidemiologic characteristics of singleton cases in Oslo, Norway, 1986\u20131995.","volume":"184","author":"JF Froen","year":"2001","journal-title":"Am J Obstet Gynecol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1080\/01443610801912618","article-title":"Methods of fetal movement counting and the detection of fetal compromise.","volume":"28","author":"AE Heazell","year":"2008","journal-title":"J Obstet Gynaecol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1576\/toag.11.4.245.27527","article-title":"Reduced fetal movements.","volume":"11","author":"J Unterscheider","year":"2009","journal-title":"The Obstetrician and Gynaecologist"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"705","DOI":"10.3109\/01443610903229598","article-title":"Predicting poor perinatal outcome in women who present with decreased fetal movements.","volume":"29","author":"O O'Sullivan","year":"2009","journal-title":"J Obstet Gynaecol"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1016\/0002-9378(82)90192-2","article-title":"Clinical implications from monitoring fetal activity.","volume":"144","author":"WF Rayburn","year":"1982","journal-title":"Am J Obstet Gynecol"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1080\/01443610601016909","article-title":"Obstetric outcome in women complaining of reduced fetal movements.","volume":"27","author":"D Sinha","year":"2007","journal-title":"J Obstet Gynaecol"},{"key":"ref12","article-title":"Identifying placental dysfunction in women with reduced fetal movements can be used to predict patients at increased risk of pregnancy complications.","author":"LK Warrander","year":"2010","journal-title":"Med Hypotheses"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1016\/0002-9378(91)90314-H","article-title":"Relationship between fetal biophysical activities and umbilical cord blood gas values.","volume":"165","author":"AM Vintzileos","year":"1991","journal-title":"Am J Obstet Gynecol"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/S0143-4004(05)80642-3","article-title":"Structural analysis of placental terminal villi from growth-restricted pregnancies with abnormal umbilical artery Doppler waveforms.","volume":"17","author":"L Macara","year":"1996","journal-title":"Placenta"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1067\/mob.2002.125243","article-title":"Decreased vascularization and cell proliferation in placentas of intrauterine growth-restricted fetuses with abnormal umbilical artery flow velocity waveforms.","volume":"187","author":"CP Chen","year":"2002","journal-title":"Am J Obstet Gynecol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1016\/S0002-9378(97)70081-4","article-title":"Increased placental apoptosis in intrauterine growth restriction.","volume":"177","author":"SC Smith","year":"1997","journal-title":"Am J Obstet Gynecol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1067\/mob.2002.122250","article-title":"Trophoblast apoptosis from pregnancies complicated by fetal growth restriction is associated with enhanced p53 expression.","volume":"186","author":"R Levy","year":"2002","journal-title":"Am J Obstet Gynecol"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1016\/S0002-9440(10)63857-6","article-title":"Differences in apoptotic susceptibility of cytotrophoblasts and syncytiotrophoblasts in normal pregnancy to those complicated with preeclampsia and intrauterine growth restriction.","volume":"162","author":"IP Crocker","year":"2003","journal-title":"Am J Pathol"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"S33","DOI":"10.1016\/j.placenta.2006.10.007","article-title":"Formation of syncytial knots is increased by hyperoxia, hypoxia and reactive oxygen species.","volume":"28","author":"AE Heazell","year":"2007","journal-title":"Placenta"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1097\/00000441-198803000-00012","article-title":"Placental amino acid uptake in normal and complicated pregnancies.","volume":"295","author":"JM Dicke","year":"1988","journal-title":"Am J Med Sci"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1203\/00006450-199710000-00016","article-title":"Association between the activity of the system A amino acid transporter in the microvillous plasma membrane of the human placenta and severity of fetal compromise in intrauterine growth restriction.","volume":"42","author":"JD Glazier","year":"1997","journal-title":"Pediatr Res"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1016\/j.humpath.2007.10.032","article-title":"Placental histologic criteria for umbilical blood flow restriction in unexplained stillbirth.","volume":"39","author":"MM Parast","year":"2008","journal-title":"Hum Pathol"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1053\/j.semperi.2008.04.004","article-title":"Fetal movement assessment.","volume":"32","author":"JF Froen","year":"2008","journal-title":"Semin Perinatol"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"705","DOI":"10.3109\/01443610903229598","article-title":"Predicting Poor Perinatal Outcome in Women who Present with Decreased Fetal Movements - A Preliminary Study.","volume":"29","author":"O O'Sullivan","year":"2009","journal-title":"Journal of Obstetrics and Gynaecology"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1053\/j.semperi.2008.04.015","article-title":"Management of decreased fetal movements.","volume":"32","author":"JF Froen","year":"2008","journal-title":"Semin Perinatol"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.earlhumdev.2007.09.017","article-title":"Gross morphological changes of placentas associated with intrauterine growth restriction of fetuses: a case control study.","volume":"84","author":"S Biswas","year":"2008","journal-title":"Early Hum Dev"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.placenta.2007.11.002","article-title":"Effects of Oxygen on Cell Turnover and Expression of Regulators of Apoptosis in Human Placental Trophoblast.","volume":"29","author":"AE Heazell","year":"2008","journal-title":"Placenta"},{"key":"ref28","first-page":"253","article-title":"In vitro methods for studying human placental amino acid transport placental villous fragments.","volume":"122","author":"SL Greenwood","year":"2006","journal-title":"Methods Mol Med"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1007\/s10495-010-0551-3","article-title":"Intra-uterine growth restriction is associated with increased apoptosis and altered expression of proteins in the p53 pathway in villous trophoblast.","volume":"16","author":"AE Heazell","year":"2011","journal-title":"Apoptosis"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/j.jsgi.2004.06.009","article-title":"An image analysis technique for the investigation of variations in placental morphology in pregnancies complicated by preeclampsia with and without intrauterine growth restriction.","volume":"11","author":"S Daayana","year":"2004","journal-title":"J Soc Gynecol Investig"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1053\/plac.2002.0826","article-title":"Glucose transport and system A activity in syncytiotrophoblast microvillous and basal plasma membranes in intrauterine growth restriction.","volume":"23","author":"T Jansson","year":"2002","journal-title":"Placenta"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1080\/01443610802716042","article-title":"Can post-mortem examination of the placenta help determine the cause of stillbirth?","volume":"29","author":"AE Heazell","year":"2009","journal-title":"J Obstet Gynaecol"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1016\/j.placenta.2009.10.001","article-title":"Centrality of the umbilical cord insertion in a human placenta influences the placental efficiency.","volume":"30","author":"M Yampolsky","year":"2009","journal-title":"Placenta"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1016\/j.placenta.2008.12.013","article-title":"Metabolic scaling law for fetus and placenta.","volume":"30","author":"CM Salafia","year":"2009","journal-title":"Placenta"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"S33","DOI":"10.1016\/j.placenta.2006.10.007","article-title":"Formation of syncytial knots is increased by hyperoxia, hypoxia and reactive oxygen species.","volume":"28","author":"AE Heazell","year":"2007","journal-title":"Placenta"},{"key":"ref36","article-title":"Term and preterm (&lt;34 and &lt;37 weeks gestation) placental pathologies associated with fetal growth restriction.","author":"L Apel-Sarid","year":"2009","journal-title":"Arch Gynecol Obstet"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1080\/00016340801902034","article-title":"Midwives&apos; and obstetricians&apos; knowledge and management of women presenting with decreased fetal movements.","volume":"87","author":"AE Heazell","year":"2008","journal-title":"Acta Obstet Gynecol Scand"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1111\/j.1479-828X.2009.01026.x","article-title":"Detection and management of decreased fetal movements in Australia and New Zealand: a survey of obstetric practice.","volume":"49","author":"V Flenady","year":"2009","journal-title":"Aust N Z J Obstet Gynaecol"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0034851","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,9]],"date-time":"2020-05-09T01:48:23Z","timestamp":1588988903000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0034851"}},"subtitle":[],"editor":[{"given":"Martin Gerbert","family":"Frasch","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2012,4,16]]},"references-count":38,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2012,4,16]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0034851","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,4,16]]}}}