{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T10:12:18Z","timestamp":1791022338137,"version":"4.1.0"},"reference-count":35,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2012,4,18]],"date-time":"2012-04-18T00:00:00Z","timestamp":1334707200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0034897","type":"journal-article","created":{"date-parts":[[2012,4,18]],"date-time":"2012-04-18T17:06:55Z","timestamp":1334768815000},"page":"e34897","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":16,"title":["X-Ray Repair Cross-Complementing Group 1 (XRCC1) Genetic Polymorphisms and Risk of Childhood Acute Lymphoblastic Leukemia: A Meta-Analysis"],"prefix":"10.1371","volume":"7","author":[{"given":"Libing","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fan","family":"Yin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xia","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoxia","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongbao","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2012,4,18]]},"reference":[{"key":"ref1","first-page":"417","article-title":"Optimal therapy for acute lymphoblastic leukemia in adolescents and young adults. Nat Rev Clin Oncol.","volume":"8","author":"ES Schafer","year":"2011"},{"key":"ref2","first-page":"1529","article-title":"Infections in early life and childhood leukaemia risk: a UK case-control study of general practitioner records. Br J Cancer.","volume":"99","author":"CR Cardwell","year":"2008"},{"key":"ref3","first-page":"1539","article-title":"Perforin polymorphism A91V and susceptibility to B-precursor childhood acute lymphoblastic leukemia: a report from the Children's Oncology Group. Leukemia.","volume":"20","author":"PA Mehta","year":"2006"},{"key":"ref4","first-page":"1405","article-title":"Candidate gene association studies and risk of childhood acute lymphoblastic leukemia: a systematic review and meta-analysis. Haematologica.","volume":"95","author":"J Vijayakrishnan","year":"2010"},{"key":"ref5","first-page":"1223","article-title":"Single-nucleotide polymorphisms in DNA repair genes and association with breast cancer risk in the web study. Carcinogenesis.","volume":"32","author":"MR Roberts","year":"2011","journal-title":"2011"},{"key":"ref6","first-page":"4945","article-title":"Association of DNA repair gene polymorphisms with response to platinum-based doublet chemotherapy in patients with non-small-cell lung cancer. J Clin Oncol.","volume":"28","author":"K Shiraishi","year":"2010"},{"key":"ref7","first-page":"3140","article-title":"Chk2-dependent phosphorylation of XRCC1 in the DNA damage response promotes base excision repair. EMBO J.","volume":"27","author":"WC Chou","year":"2008"},{"key":"ref8","first-page":"13738","article-title":"In situ analysis of repair processes for oxidative DNA damage in mammalian cells. Proc Natl Acad Sci U S A.","volume":"101","author":"L Lan","year":"2007"},{"key":"ref9","first-page":"17","article-title":"DNA repair gene XRCC1 polymorphisms in childhood acute lymphoblastic leukemia. Cancer Lett.","volume":"217","author":"T Joseph","year":"2005"},{"key":"ref10","first-page":"16","article-title":"Genetic polymorphisms and haplotypes of DNA repair genes in childhood acute lymphoblastic leukemia. Pediatr Blood Cancer.","volume":"48","author":"S Pakakasama","year":"2007"},{"key":"ref11","first-page":"759","article-title":"DNA repair gene XPD and XRCC1 polymorphisms and the risk of childhood acute lymphoblastic leukemia. Leuk Res.","volume":"33","author":"B Batar","year":"2009"},{"key":"ref12","first-page":"1451","article-title":"XRCC1 polymorphisms and haplotypes in Mexican patients with acute lymphoblastic leukemia. Genet Mol Res.","volume":"8","author":"JP Meza-Espinoza","year":"2009"},{"key":"ref13","first-page":"1275","article-title":"DNA repair XRCC1 Arg399Gln polymorphism alone, and in combination with CYP2E1 polymorphisms significantly contribute to the risk of development of childhood acute lymphoblastic leukemia. Leuk Res.","volume":"34","author":"TB Tumer","year":"2010"},{"key":"ref14","first-page":"1118","article-title":"Impact of thymidylate synthase promoter and DNA repair gene polymorphisms on susceptibility to childhood acute lymphoblastic leukemia. Leuk Lymphoma.","volume":"52","author":"R Canalle","year":"2011"},{"key":"ref15","first-page":"445","article-title":"The association of polymorphisms in DNA base excision repair genes XRCC1, OGG1 and MUTYH with the risk of childhood acute lymphoblastic leukemia. Mol Biol Rep.","volume":"30","author":"M Stanczyk","year":"2011"},{"key":"ref16","first-page":"101","article-title":"The combination of estimates from different experiments. Biometrics.","volume":"10","author":"WG Cochran","year":"1954"},{"key":"ref17","first-page":"719","article-title":"Statistical aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst.","volume":"22","author":"N Mantel","year":"1959"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/0197-2456(86)90046-2","article-title":"Meta-analysis in clinical trials.","volume":"7","author":"R DerSimonian","year":"1986","journal-title":"Control Clin Trials"},{"key":"ref19","first-page":"629","article-title":"Bias in meta-analysis detected by a simple, graphical test. BMJ.","volume":"315","author":"M Egger","year":"1997"},{"key":"ref20","first-page":"15","article-title":"Assessing the influence of a single study in the meta-analysis estimate. Stata Tecnol Bull.","volume":"8","author":"A Tobias","year":"1999"},{"key":"ref21","first-page":"802","article-title":"Polymorphisms in genes encoding drugs and xenobiotic metabolizing enzymes, DNA repair enzymes, and response to treatment of childhood acute lymphoblastic leukemia. Clin Cancer Res.","volume":"8","author":"M Krajinovic","year":"2002"},{"key":"ref22","first-page":"898","article-title":"Polymorphisms of xenobiotic metabolizing enzymes and DNA repair genes and outcome in childhood acute lymphoblastic leukemia. Leuk Res.","volume":"33","author":"V da Silva Silveira","year":"2009"},{"key":"ref23","first-page":"431","article-title":"Association between polymorphisms of EPHX1 and XRCC1 genes and the risk of childhood acute lymphoblastic leukemia. Arch Toxicol.","volume":"86","author":"TB Tumer","year":"2012"},{"key":"ref24","first-page":"267","article-title":"Association of genetic polymorphisms in the base excision repair pathway with lung cancer risk: a meta-analysis. Lung Cancer.","volume":"54","author":"C Kiyohara","year":"2006"},{"key":"ref25","first-page":"137","article-title":"Polymorphism of XRCC1 (at codon 399) and susceptibility to breast cancer, a meta-analysis of the literatures. Breast Cancer Res Treat.","volume":"115","author":"M Saadat","year":"2009"},{"key":"ref26","first-page":"4648","article-title":"XRCC1 genetic polymorphism Arg399Gln and prostate cancer risk: a meta-analysis. Urology.","volume":"72","author":"J Geng","year":"2009"},{"key":"ref27","first-page":"363","article-title":"X-ray repair cross-complementing group 1 (XRCC1) genetic polymorphisms and gastric cancer risk: A HuGE review and meta-analysis. Am J Epidemiol.","volume":"173","author":"H Xue","year":"2011"},{"key":"ref28","first-page":"869","article-title":"XRCC1 genetic polymorphisms and bladder cancer susceptibility: a meta-analysis. Urology.","volume":"72","author":"C Wang","year":"2008"},{"key":"ref29","first-page":"600","article-title":"Polymorphisms of DNA repair Genes XRCC1 and XPD and their associations with risk of esophageal squamous cell carcinoma in a Chinese population. Int J Cancer.","volume":"100","author":"D Xing","year":"2002"},{"key":"ref30","first-page":"53","article-title":"Genetic polymorphisms of XRCC1 and risk of gastric cancer. Cancer Lett.","volume":"187","author":"SG Lee","year":"2002"},{"key":"ref31","first-page":"160","article-title":"Genetic polymorphisms in DNA repair gene APE1, XRCC1 and XPD and the risk of preeclampsia. Eur J Obstet Gynecol Reprod Biol.","volume":"146","author":"P Vural","year":"2009"},{"key":"ref32","first-page":"887","article-title":"Head and neck squamous-cell cancer and its association with polymorphic enzymes of xenobiotic metabolism and repair. J Toxicol Environ Health A.","volume":"71","author":"V Harth","year":"2008"},{"key":"ref33","first-page":"1","article-title":"Association study between XRCC1 gene polymorphisms and sporadic amyotrophic lateral sclerosis. Amyotroph Lateral Scler.","volume":"25","author":"F Copped\u00e8","year":"2009"},{"key":"ref34","first-page":"869","article-title":"XRCC1 genetic polymorphisms and bladder cancer susceptibility: a meta-analysis. Urology.","volume":"72","author":"C Wang","year":"2008"},{"key":"ref35","first-page":"523","article-title":"A meta-analysis on XRCC1 R399Q and R194W polymorphisms, smoking and bladder cancer risk. Mutagenesis.","volume":"23","author":"T Lao","year":"2008"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0034897","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,10,26]],"date-time":"2018-10-26T01:26:06Z","timestamp":1540517166000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0034897"}},"subtitle":[],"editor":[{"given":"Rui","family":"Medeiros","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2012,4,18]]},"references-count":35,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2012,4,18]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0034897","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,4,18]]}}}