{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T07:04:55Z","timestamp":1790665495775,"version":"4.1.0"},"reference-count":75,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2012,4,30]],"date-time":"2012-04-30T00:00:00Z","timestamp":1335744000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0036247","type":"journal-article","created":{"date-parts":[[2012,4,30]],"date-time":"2012-04-30T20:55:01Z","timestamp":1335819301000},"page":"e36247","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":17,"title":["Methionine Sulfoxide Reductase A (MsrA) Deficient Mycoplasma genitalium Shows Decreased Interactions with Host Cells"],"prefix":"10.1371","volume":"7","author":[{"given":"Kishore","family":"Das","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georgina","family":"De la Garza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shivani","family":"Maffi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sankaralingam","family":"Saikolappan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Subramanian","family":"Dhandayuthapani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2012,4,30]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1136\/sti.2004.010439","article-title":"Signs and symptoms of urethritis and cervicitis among women with or without <italic>Mycoplasma genitalium<\/italic> or <italic>Chlamydia trachomatis<\/italic> infection.","volume":"81","author":"L Falk","year":"2005","journal-title":"Sex Transm Infect"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1097\/OLQ.0b013e3181b01948","article-title":"<italic>Mycoplasma genitalium<\/italic> as a contributor to the multiple etiologies of cervicitis in women attending sexually transmitted disease clinics.","volume":"36","author":"C Gaydos","year":"2009","journal-title":"Sex Transm Dis"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1258\/095646204322637209","article-title":"<italic>Mycoplasma genitalium<\/italic> in chronic non-gonococcal urethritis.","volume":"15","author":"D Taylor-Robinson","year":"2004","journal-title":"Int J STD AIDS"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1086\/594123","article-title":"Clinical presentation of <italic>Mycoplasma genitalium<\/italic> Infection versus <italic>Neisseria gonorrhoeae<\/italic> infection among women with pelvic inflammatory disease.","volume":"48","author":"VL Short","year":"2009","journal-title":"Clin Infect Dis"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1136\/sti.2009.037721","article-title":"The demographic, sexual health and behavioural correlates of <italic>Mycoplasma genitalium<\/italic> infection among women with clinically suspected pelvic inflammatory disease.","volume":"86","author":"VL Short","year":"2009","journal-title":"Sex Transm Infect"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1016\/S0140-6736(02)07848-0","article-title":"Association between <italic>Mycoplasma genitalium<\/italic> and acute endometritis.","volume":"359","author":"CR Cohen","year":"2002","journal-title":"Lancet"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1097\/QAD.0b013e328323da3e","article-title":"Association of <italic>Mycoplasma genitalium<\/italic> and HIV infection: a systematic review and meta-analysis.","volume":"23","author":"S Napierala Mavedzenge","year":"2009","journal-title":"AIDS"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"S137","DOI":"10.1164\/ajrccm\/154.4_Pt_2.S137","article-title":"Interplay between mycoplasma surface proteins, airway cells, and the protean manifestations of mycoplasma-mediated human infections.","volume":"154","author":"JB Baseman","year":"1996","journal-title":"Am J Respir Crit Care Med"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"5943","DOI":"10.1128\/jb.177.20.5943-5951.1995","article-title":"Molecular cloning and characterization of an adherence-related operon of <italic>Mycoplasma genitalium<\/italic>.","volume":"177","author":"SP Reddy","year":"1995","journal-title":"J Bacteriol"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"5227","DOI":"10.1073\/pnas.96.9.5227","article-title":"Disruption of gene mg218 of <italic>Mycoplasma genitalium<\/italic> through homologous recombination leads to an adherence-deficient phenotype.","volume":"96","author":"S Dhandayuthapani","year":"1999","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"3188","DOI":"10.1099\/mic.0.2008\/020636-0","article-title":"Role of <italic>Mycoplasma genitalium<\/italic> MG218 and MG317 cytoskeletal proteins in terminal organelle organization, gliding motility and cytadherence.","volume":"154","author":"OQ Pich","year":"2008","journal-title":"Microbiology"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1006\/mpat.1995.0050","article-title":"Interplay between mycoplasmas and host target cells.","volume":"19","author":"JB Baseman","year":"1995","journal-title":"Microb Pathog"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1006\/mpat.2000.0395","article-title":"Intracellular DNA replication and long-term survival of pathogenic mycoplasmas.","volume":"29","author":"SF Dallo","year":"2000","journal-title":"Microb Pathog"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1111\/j.1574-695X.2007.00366.x","article-title":"<italic>Mycoplasma genitalium<\/italic>-derived lipid-associated membrane proteins induce activation of MAPKs, NF-kappaB and AP-1 in THP-1 cells.","volume":"52","author":"X You","year":"2008","journal-title":"FEMS Immunol Med Microbiol"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1631\/jzus.2006.B0342","article-title":"Interactions between mycoplasma lipid-associated membrane proteins and the host cells.","volume":"7","author":"XX You","year":"2006","journal-title":"J Zhejiang Univ Sci B"},{"key":"ref16","first-page":"195427","article-title":"<italic>Mycoplasma genitalium<\/italic> lipoproteins induce human monocytic cell expression of proinflammatory cytokines and apoptosis by activating nuclear factor kappaB.","volume":"2008","author":"Y Wu","year":"2008","journal-title":"Mediators Inflamm"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"8841","DOI":"10.1073\/pnas.97.16.8841","article-title":"Reactive oxygen and nitrogen intermediates in the relationship between mammalian hosts and microbial pathogens.","volume":"97","author":"C Nathan","year":"2000","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1006\/abbi.2001.2642","article-title":"The neutrophil NADPH oxidase.","volume":"397","author":"BM Babior","year":"2002","journal-title":"Arch Biochem Biophys"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"3007","DOI":"10.1182\/blood.V92.9.3007","article-title":"Inside the neutrophil phagosome: oxidants, myeloperoxidase, and bacterial killing.","volume":"92","author":"MB Hampton","year":"1998","journal-title":"Blood"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1111\/j.1365-313X.2004.02271.x","article-title":"Analysis of the proteins targeted by CDSP32, a plastidic thioredoxin participating in oxidative stress responses.","volume":"41","author":"P Rey","year":"2005","journal-title":"Plant J"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"1620","DOI":"10.1073\/pnas.87.4.1620","article-title":"Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide.","volume":"87","author":"JS Beckman","year":"1990","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref22","first-page":"215","article-title":"Nitric Oxide in Tuberculosis.","author":"CF Nathan","year":"2004"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"6675","DOI":"10.1128\/JB.01066-08","article-title":"The <italic>Mycoplasma genitalium<\/italic> MG_454 gene product resists killing by organic hydroperoxides.","volume":"191","author":"S Saikolappan","year":"2009","journal-title":"J Bacteriol"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1006\/abbi.2001.2664","article-title":"Peptide methionine sulfoxide reductase: structure, mechanism of action, and biological function.","volume":"397","author":"H Weissbach","year":"2002","journal-title":"Arch Biochem Biophys"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"48915","DOI":"10.1074\/jbc.M105509200","article-title":"Repair of oxidized proteins. Identification of a new methionine sulfoxide reductase.","volume":"276","author":"R Grimaud","year":"2001","journal-title":"J Biol Chem"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"37527","DOI":"10.1074\/jbc.M203496200","article-title":"Reaction mechanism, evolutionary analysis, and role of zinc in Drosophila methionine-R-sulfoxide reductase.","volume":"277","author":"RA Kumar","year":"2002","journal-title":"J Biol Chem"},{"key":"ref27","first-page":"348","article-title":"The mirrored methionine sulfoxide reductases of <italic>Neisseria gonorrhoeae<\/italic> pilB.","volume":"9","author":"WT Lowther","year":"2002","journal-title":"Nat Struct Biol"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1007\/s00438-002-0692-3","article-title":"Reverse genetic approaches in plants and yeast suggest a role for novel, evolutionarily conserved, selenoprotein-related genes in oxidative stress defense.","volume":"267","author":"MJ Rodrigo","year":"2002","journal-title":"Mol Genet Genomics"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.bbapap.2004.09.016","article-title":"The enzymology and biochemistry of methionine sulfoxide reductases.","volume":"1703","author":"S Boschi-Muller","year":"2005","journal-title":"Biochim Biophys Acta"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.bbapap.2004.10.004","article-title":"Methionine sulfoxide reductases: history and cellular role in protecting against oxidative damage.","volume":"1703","author":"H Weissbach","year":"2005","journal-title":"Biochim Biophys Acta"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"619","DOI":"10.2217\/17460913.2.6.619","article-title":"Methionine sulfoxide reductases and virulence of bacterial pathogens.","volume":"2","author":"SJ Sasindran","year":"2007","journal-title":"Future Microbiol"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.bbapap.2004.08.017","article-title":"Methionine sulfoxide reductases in prokaryotes.","volume":"1703","author":"B Ezraty","year":"2005","journal-title":"Biochim Biophys Acta"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"3695","DOI":"10.1099\/00221287-148-11-3695","article-title":"Peptide methionine sulfoxide reductase (MsrA) is not a major virulence determinant for the oral pathogen <italic>Actinobacillus actinomycetemcomitans<\/italic>.","volume":"148","author":"KP Mintz","year":"2002","journal-title":"Microbiology"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1111\/j.1365-2958.2008.06548.x","article-title":"<italic>Mycobacterium tuberculosis<\/italic> expresses methionine sulphoxide reductases A and B that protect from killing by nitrite and hypochlorite.","volume":"71","author":"WL Lee","year":"2009","journal-title":"Mol Microbiol"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1111\/j.1365-2958.2004.04190.x","article-title":"Methionine sulphoxide reductase is an important antioxidant enzyme in the gastric pathogen <italic>Helicobacter pylori<\/italic>.","volume":"53","author":"P Alamuri","year":"2004","journal-title":"Mol Microbiol"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"5645","DOI":"10.1128\/JB.183.19.5645-5650.2001","article-title":"Peptide methionine sulfoxide reductase (MsrA) is a virulence determinant in <italic>Mycoplasma genitalium<\/italic>.","volume":"183","author":"S Dhandayuthapani","year":"2001","journal-title":"J Bacteriol"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"3590","DOI":"10.1128\/JB.186.11.3590-3598.2004","article-title":"Methionine sulfoxide reductase A (MsrA) deficiency affects the survival of <italic>Mycobacterium smegmatis<\/italic> within macrophages.","volume":"186","author":"T Douglas","year":"2004","journal-title":"J Bacteriol"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1073\/pnas.96.3.887","article-title":"The minimal gene set member msrA, encoding peptide methionine sulfoxide reductase, is a virulence determinant of the plant pathogen <italic>Erwinia chrysanthemi<\/italic>.","volume":"96","author":"ME Hassouni","year":"1999","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1128\/jb.177.3.502-507.1995","article-title":"<italic>Escherichia coli<\/italic> peptide methionine sulfoxide reductase gene: regulation of expression and role in protecting against oxidative damage.","volume":"177","author":"J Moskovitz","year":"1995","journal-title":"J Bacteriol"},{"key":"ref40","first-page":"79","article-title":"Cell wall-active antibiotic induced proteins of <italic>Staphylococcus aureus<\/italic> identified using a proteomic approach.","volume":"199","author":"VK Singh","year":"2001","journal-title":"FEMS Microbiol Lett"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"5831","DOI":"10.1128\/JB.187.16.5831-5836.2005","article-title":"Important role for methionine sulfoxide reductase in the oxidative stress response of <italic>Xanthomonas campestris pv. phaseoli<\/italic>.","volume":"187","author":"P Vattanaviboon","year":"2005","journal-title":"J Bacteriol"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"e26974","DOI":"10.1371\/journal.pone.0026974","article-title":"Methionine sulfoxide reductases are essential for virulence of <italic>Salmonella typhimurium<\/italic>.","volume":"6","author":"LA Denkel","year":"2011","journal-title":"PLoS One"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"7985","DOI":"10.1073\/pnas.93.15.7985","article-title":"Peptide methionine sulfoxide reductase contributes to the maintenance of adhesins in three major pathogens.","volume":"93","author":"TM Wizemann","year":"1996","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1111\/j.1574-6968.2006.00479.x","article-title":"Binding of <italic>Streptococcus gordonii<\/italic> to extracellular matrix proteins.","volume":"265","author":"B Giomarelli","year":"2006","journal-title":"FEMS Microbiol Lett"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"2101","DOI":"10.1902\/jop.2005.76.11-S.2101","article-title":"Oral streptococci and cardiovascular disease: searching for the platelet aggregation-associated protein gene and mechanisms of <italic>Streptococcus sanguis<\/italic>-induced thrombosis.","volume":"76","author":"MC Herzberg","year":"2005","journal-title":"J Periodontol"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1046\/j.1365-2958.2003.03865.x","article-title":"Global impact of mature biofilm lifestyle on <italic>Escherichia coli K-12<\/italic> gene expression.","volume":"51","author":"C Beloin","year":"2004","journal-title":"Mol Microbiol"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1111\/j.1365-2958.2006.05099.x","article-title":"<italic>Streptococcus gordonii<\/italic> utilizes several distinct gene functions to recruit <italic>Porphyromonas gingivalis<\/italic> into a mixed community.","volume":"60","author":"M Kuboniwa","year":"2006","journal-title":"Mol Microbiol"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1046\/j.1365-2958.1997.5911966.x","article-title":"Identification of <italic>Staphylococcus aureus<\/italic> virulence genes in a murine model of bacteraemia using signature-tagged mutagenesis.","volume":"26","author":"JM Mei","year":"1997","journal-title":"Mol Microbiol"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1038\/nprot.2006.179","article-title":"Sulforhodamine B colorimetric assay for cytotoxicity screening.","volume":"1","author":"V Vichai","year":"2006","journal-title":"Nat Protoc"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1189\/jlb.0905522","article-title":"Detection and properties of the human proliferative monocyte subpopulation.","volume":"79","author":"FI Clanchy","year":"2006","journal-title":"J Leukoc Biol"},{"key":"ref51","first-page":"14.51","article-title":"Measurement of bacterial ingestion and killing by macrophages","author":"P Campbell","year":"1994"},{"key":"ref52","first-page":"Unit 14 19 11","article-title":"In vivo and ex vivo protocols for measuring the killing of extracellular pathogens by macrophages.","volume":"14","author":"E Medina","year":"2011","journal-title":"Curr Protoc Immunol Chapter"},{"key":"ref53","first-page":"22","article-title":"Cell lysis and Isolation of Membranes.","author":"S Razin","year":"1983"},{"key":"ref54","article-title":"Current Prtocols in Molecular Biology","author":"F Ausubel","year":"1989"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"3533","DOI":"10.1128\/IAI.00081-09","article-title":"Amino acid changes in elongation factor Tu of <italic>Mycoplasma pneumoniae<\/italic> and <italic>Mycoplasma genitalium<\/italic> influence fibronectin binding.","volume":"77","author":"S Balasubramanian","year":"2009","journal-title":"Infect Immun"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"4388","DOI":"10.1128\/JB.00578-10","article-title":"Localization and cellular amounts of the WalRKJ (VicRKX) two-component regulatory system proteins in serotype 2 <italic>Streptococcus pneumoniae<\/italic>.","volume":"192","author":"KJ Wayne","year":"2010","journal-title":"J Bacteriol"},{"key":"ref57","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1126\/science.150.3693.226","article-title":"Hemolysin of <italic>Mycoplasma pneumoniae<\/italic>: tentative identification as a peroxide.","volume":"150","author":"NL Somerson","year":"1965","journal-title":"Science"},{"key":"ref58","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1128\/CDLI.8.1.85-92.2001","article-title":"Genetic and biochemical characterization of glycerol uptake in <italic>mycoplasma mycoides<\/italic> subsp. mycoides SC: its impact on H(2)O(2) production and virulence.","volume":"8","author":"EM Vilei","year":"2001","journal-title":"Clin Diagn Lab Immunol"},{"key":"ref59","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1186\/1471-2180-9-139","article-title":"Intracellular <italic>Mycoplasma genitalium<\/italic> infection of human vaginal and cervical epithelial cells elicits distinct patterns of inflammatory cytokine secretion and provides a possible survival niche against macrophage-mediated killing.","volume":"9","author":"CL McGowin","year":"2009","journal-title":"BMC Microbiol"},{"key":"ref60","doi-asserted-by":"crossref","first-page":"2837","DOI":"10.1099\/mic.0.2008\/017574-0","article-title":"The LysR-type transcriptional regulator Hrg counteracts phagocyte oxidative burst and imparts survival advantage to <italic>Salmonella enterica serovar Typhimurium<\/italic>.","volume":"154","author":"A Lahiri","year":"2008","journal-title":"Microbiology"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"3188","DOI":"10.1128\/IAI.67.7.3188-3192.1999","article-title":"Effects of <italic>Mycoplasma fermentans<\/italic> incognitus on differentiation of THP-1 cells.","volume":"67","author":"L Reyes","year":"1999","journal-title":"Infect Immun"},{"key":"ref62","doi-asserted-by":"crossref","first-page":"2328","DOI":"10.1099\/mic.0.048298-0","article-title":"Role of <italic>Mycoplasma pneumoniae<\/italic> glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in mediating interactions with the human extracellular matrix.","volume":"157","author":"R Dumke","year":"2011","journal-title":"Microbiology"},{"key":"ref63","doi-asserted-by":"crossref","first-page":"6824","DOI":"10.1128\/JB.187.19.6824-6831.2005","article-title":"A metabolic enzyme as a primary virulence factor of <italic>Mycoplasma mycoides<\/italic> subsp. mycoides small colony.","volume":"187","author":"P Pilo","year":"2005","journal-title":"J Bacteriol"},{"key":"ref64","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1128\/JB.01103-08","article-title":"Glycerol metabolism is important for cytotoxicity of <italic>Mycoplasma pneumoniae<\/italic>.","volume":"191","author":"C Hames","year":"2009","journal-title":"J Bacteriol"},{"issue":"Pt 2","key":"ref65","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1099\/00221287-146-2-477","article-title":"Genomic and antigenic differences between the European and African\/Australian clusters of <italic>Mycoplasma mycoides<\/italic> subsp. mycoides SC.","volume":"146","author":"EM Vilei","year":"2000","journal-title":"Microbiology"},{"key":"ref66","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1128\/IAI.00938-07","article-title":"Cytotoxicity of <italic>Mycoplasma mycoides<\/italic> subsp. mycoides small colony type to bovine epithelial cells.","volume":"76","author":"DF Bischof","year":"2008","journal-title":"Infect Immun"},{"key":"ref67","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1126\/science.270.5235.397","article-title":"The minimal gene complement of <italic>Mycoplasma genitalium<\/italic>.","volume":"270","author":"CM Fraser","year":"1995","journal-title":"Science"},{"key":"ref68","first-page":"91","article-title":"Intracellular location of <italic>Mycoplasma genitalium<\/italic> in cultured Vero cells as demonstrated by electron microscopy.","volume":"75","author":"JS Jensen","year":"1994","journal-title":"Int J Exp Pathol"},{"key":"ref69","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1139\/W07-125","article-title":"Apoptosis induced by lipid-associated membrane proteins from <italic>Mycoplasma penetrans<\/italic> is mediated by nuclear factor kappaB activation in mouse macrophage.","volume":"54","author":"Y Zeng","year":"2008","journal-title":"Can J Microbiol"},{"key":"ref70","doi-asserted-by":"crossref","first-page":"1750","DOI":"10.1128\/CVI.00281-09","article-title":"<italic>Mycoplasma genitalium<\/italic>-derived lipid-associated membrane proteins activate NF-kappaB through toll-like receptors 1, 2, and 6 and CD14 in a MyD88-dependent pathway.","volume":"16","author":"J He","year":"2009","journal-title":"Clin Vaccine Immunol"},{"key":"ref71","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1128\/IAI.00845-08","article-title":"<italic>Mycoplasma genitalium<\/italic>-encoded MG309 activates NF-kappaB via Toll-like receptors 2 and 6 to elicit proinflammatory cytokine secretion from human genital epithelial cells.","volume":"77","author":"CL McGowin","year":"2009","journal-title":"Infect Immun"},{"key":"ref72","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1631\/jzus.B0820256","article-title":"Mycoplasma lipoproteins and Toll-like receptors.","volume":"10","author":"LL Zuo","year":"2009","journal-title":"J Zhejiang Univ Sci B"},{"key":"ref73","doi-asserted-by":"crossref","first-page":"10108","DOI":"10.1073\/pnas.152334799","article-title":"The outer membrane localization of the <italic>Neisseria gonorrhoeae<\/italic> MsrA\/B is involved in survival against reactive oxygen species.","volume":"99","author":"EP Skaar","year":"2002","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref74","doi-asserted-by":"crossref","first-page":"2748","DOI":"10.1128\/IAI.69.4.2748-2752.2001","article-title":"Identification of the exported proteins of the oral opportunistic pathogen <italic>Actinobacillus actinomycetemcomitans<\/italic> by using alkaline phosphatase fusions.","volume":"69","author":"J Ward","year":"2001","journal-title":"Infect Immun"},{"key":"ref75","doi-asserted-by":"crossref","first-page":"2984","DOI":"10.1128\/IAI.66.6.2984-2986.1998","article-title":"Extracellular release of antigenic proteins by <italic>Helicobacter pylori<\/italic>.","volume":"66","author":"P Cao","year":"1998","journal-title":"Infect Immun"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0036247","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,6]],"date-time":"2020-07-06T23:13:45Z","timestamp":1594077225000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0036247"}},"subtitle":[],"editor":[{"given":"David M.","family":"Ojcius","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2012,4,30]]},"references-count":75,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2012,4,30]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0036247","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,4,30]]}}}