{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T03:04:41Z","timestamp":1777431881911,"version":"3.51.4"},"reference-count":66,"publisher":"Public Library of Science (PLoS)","issue":"6","license":[{"start":{"date-parts":[[2012,6,8]],"date-time":"2012-06-08T00:00:00Z","timestamp":1339113600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0038116","type":"journal-article","created":{"date-parts":[[2012,6,8]],"date-time":"2012-06-08T22:52:29Z","timestamp":1339195949000},"page":"e38116","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":35,"title":["Paradoxical Facilitation of Working Memory after Basolateral Amygdala Damage"],"prefix":"10.1371","volume":"7","author":[{"given":"Barak","family":"Morgan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Terburg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helena B.","family":"Thornton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dan J.","family":"Stein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jack","family":"van Honk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2012,6,8]]},"reference":[{"key":"ref1","first-page":"152","article-title":"Working memory or working attention?","author":"A Baddeley","year":"1993"},{"key":"ref2","article-title":"Working memory as an emergent property of the mind. Neuroscience 139: 23\u201338.","author":"BR Postle","year":"2006"},{"key":"ref3","article-title":"The functional neuroanatomy of working memory: contributions of human brain lesion studies. Neuroscience 139: 51\u201358.","author":"NG M\u00fcller","year":"2006"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.tics.2010.04.004","article-title":"Large-scale brain networks in cognition: emerging methods and principles.","volume":"14","author":"S Bressler","year":"2010","journal-title":"Trends in Cognitive Sciences"},{"key":"ref5","article-title":"Brain systems mediating cognitive interference by emotional distraction. The Journal of Neuroscience 26: 2072\u20132079.","author":"F Dolcos","year":"2006"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"1679","DOI":"10.1162\/089892905774589208","article-title":"Delay-period activity in the prefrontal cortex: one function is sensory gating.","volume":"17","author":"B Postle","year":"2005","journal-title":"Journal of Cognitive Neuroscience"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1038\/nn846","article-title":"Active maintenance in prefrontal area 46 creates distractor-resistant memory.","volume":"5","author":"K Sakai","year":"2002","journal-title":"Nature Neuroscience"},{"key":"ref8","article-title":"Interactions between orbital prefrontal cortex and amygdala: advanced cognition, learned responses and instinctive behaviors. Current Opinion in Neurobiology 20: 212\u2013220.","author":"E Murray","year":"2010"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1038\/sj.mp.4000812","article-title":"The amygdala: vigilance and emotion.","volume":"6","author":"M Davis","year":"2001","journal-title":"Molecular Psychiatry"},{"key":"ref10","article-title":"Fear, vigilance, and ambiguity: initial neuroimaging studies of the human amygdala. Current Directions in Psychological Science 7: 177\u2013188.","author":"PJ Whalen","year":"1998"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1515\/REVNEURO.2003.14.4.303","article-title":"The human amygdala: an evolved system for relevance detection.","volume":"14","author":"D Sander","year":"2003","journal-title":"Reviews in the Neurosciences"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1515\/revneuro.2007.18.5.355","article-title":"A Role For the Human Amygdala in Higher Cognition.","volume":"18","author":"A Schaefer","year":"2007","journal-title":"Reviews in the neurosciences"},{"key":"ref13","article-title":"Changes in cortical morphology resulting from long-term amygdala damage. Social Cognitive and Affective Neuroscience.","author":"AD Boes","year":"2011"},{"key":"ref14","article-title":"Individual differences in amygdala activity predict response speed during working memory. System 26: 10120\u201310128.","author":"A Schaefer","year":"2006"},{"key":"ref15","article-title":"Working memory overload: fronto-limbic interactions and effects on subsequent working memory function. Brain Imaging and Behavior 4: 96\u2013108.","author":"RJ Yun","year":"2010"},{"key":"ref16","article-title":"Resisting emotional interference: brain regions facilitating working memory performance during negative distraction. Cognitive, Affective & Behavioral Neuroscience 10: 159\u2013173.","author":"A Anticevic","year":"2010"},{"key":"ref17","article-title":"Functional internal complexity of amygdala: focus on gene activity mapping after behavioral training and drugs of abuse. Physiological Reviews 87: 1113\u20131173.","author":"E Knapska","year":"2007"},{"key":"ref18","article-title":"Emotion, cognition, and mental state representation in amygdala and prefrontal cortex. Annual Review of Neuroscience 33: 173\u2013202.","author":"CD Salzman","year":"2010"},{"key":"ref19","article-title":"Conditioned and unconditioned fear organized in the periaqueductal gray are differentially sensitive to injections of muscimol into amygdaloid nuclei. Neurobiology of Learning and Memory 85: 58\u201365.","author":"RCR Martinez","year":"2006"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1126\/science.1144298","article-title":"When fear is near: threat imminence elicits prefrontal-periaqueductal gray shifts in humans.","volume":"317","author":"D Mobbs","year":"2007","journal-title":"Science"},{"key":"ref21","article-title":"For better or for worse: neural systems supporting the cognitive down- and up-regulation of negative emotion. NeuroImage 23: 483\u2013499.","author":"KN Ochsner","year":"2004"},{"key":"ref22","article-title":"Neural correlates of variations in event processing during learning in basolateral amygdala. The Journal of Neuroscience 30: 2464\u20132471.","author":"MR Roesch","year":"2010"},{"key":"ref23","article-title":"Neuroanatomy of the primate amygdala.","author":"J Freese","year":"2009"},{"key":"ref24","article-title":"Disrupted amygdalar subregion functional connectivity and evidence of a compensatory network in generalized anxiety disorder. Archives of General Psychiatry 66: 1361\u20131372.","author":"A Etkin","year":"2009"},{"key":"ref25","first-page":"1261","article-title":"Pathways for emotion: interactions of prefrontal and anterior temporal pathways in the amygdala of the rhesus monkey.","volume":"115","author":"HT Ghashghaei","year":"2002","journal-title":"Science"},{"key":"ref26","article-title":"Basolateral amygdala lesions abolish orbitofrontal-dependent reversal impairments. Neuron 54: 51\u201358.","author":"TA Stalnaker","year":"2007"},{"key":"ref27","article-title":"The neuropsychiatry and neuropsychology of lipoid proteinosis. Journal of Neuropsychiatry and Clinical Neurosciences 20: 86\u201392.","author":"H Thornton","year":"2008"},{"key":"ref28","article-title":"Wechsler Abbreviated Scale of Intelligence, San Antonio, TX: Psychological Corporation.","author":"D Wechsler","year":"1999"},{"key":"ref29","article-title":"Wechsler Adult Intelligence Scale-III, San Antonio, TX: Psychological Corporation.","author":"D Weschler","year":"1997"},{"key":"ref30","article-title":"Quarterly Labour Force Survey Quarter 1, 2011.","author":"Africa Statistics South","year":"2011"},{"key":"ref31","article-title":"The weirdest people in the world? The Behavioral and Brain Sciences 33: 61\u201383.","author":"J Henrich","year":"2010"},{"key":"ref32","article-title":"Most people are not WEIRD. Nature 466: 29.","author":"J Henrich","year":"2010"},{"key":"ref33","article-title":"Psychology. A WEIRD view of human nature skews psychologists\u2019 studies. Science 328: 1627.","author":"D Jones","year":"2010"},{"key":"ref34","article-title":"Cross-cultural neuropsychological assessment: theory and practice. New Jersey: Lawrence Erlbaum Associates.","author":"V Nell","year":"2000"},{"key":"ref35","article-title":"Cytoarchitectonic mapping of the human amygdala, hippocampal region and entorhinal cortex: intersubject variability and probability maps. Anatomy and Embryology 210: 343\u2013352.","author":"K Amunts","year":"2005"},{"key":"ref36","article-title":"Diffusion tensor imaging segments the human amygdala in vivo. Neuroimage 49: 2958\u20132965.","author":"E Solano-Castiella","year":"2010"},{"key":"ref37","article-title":"SPM - Statistical Parametric Mapping."},{"key":"ref38","article-title":"Spatial normalization of lesioned brains: performance evaluation and impact on fMRI analyses. Neuroimage 37: 866\u2013875.","author":"J Crinion","year":"2007"},{"key":"ref39","article-title":"SPM - Statistical Parametric Mapping."},{"key":"ref40","article-title":"Accessed 2012 May 7."},{"key":"ref41","article-title":"Assignment of functional activations to probabilistic cytoarchitectonic areas revisited. Neuroimage 36: 511\u2013521.","author":"SB Eickhoff","year":"2007"},{"key":"ref42","article-title":"Serotonin transporter genetic variation and the response of the human amygdala. Science 297: 400\u2013403.","author":"AR Hariri","year":"2002"},{"key":"ref43","article-title":"Temporal stability of individual differences in amygdala reactivity. American Journal of Psychiatry 164: 1613\u20131614.","author":"SB Manuck","year":"2007"},{"key":"ref44","article-title":"Preclinical atherosclerosis covaries with individual differences in reactivity and functional connectivity of the amygdala. Biological Psychiatry 65: 943\u2013950.","author":"PJ Gianaros","year":"2009"},{"key":"ref45","article-title":"The NimStim set of facial expressions: judgments from untrained research participants. Psychiatry Research 168: 242\u2013249.","author":"N Tottenham","year":"2009"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1002\/hbm.460030303","article-title":"Spatial registration and normalization of images.","volume":"2","author":"KJ Friston","year":"1995","journal-title":"Human Brain Mapping"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1002\/hbm.460020402","article-title":"Statistical parametric maps in functional imaging: A general linear approach.","volume":"2","author":"KJ Friston","year":"1995","journal-title":"Human Brain Mapping"},{"key":"ref48","article-title":"A new SPM toolbox for combining probabilistic cytoarchitectonic maps and functional imaging data. Neuroimage 25: 1325\u20131335.","author":"SB Eickhoff","year":"2005"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"2627","DOI":"10.1093\/brain\/awg271","article-title":"Amygdala, affect and cognition: evidence from 10 patients with Urbach-Wiethe disease.","volume":"126","author":"M Siebert","year":"2003","journal-title":"Brain"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"13626","DOI":"10.1073\/pnas.1635116100","article-title":"An emotion-induced retrograde amnesia in humans is amygdala- and beta-adrenergic-dependent.","volume":"100","author":"BA Strange","year":"2003","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"ref51","article-title":"Impaired recognition of emotion in facial expressions following bilateral damage to the human amygdala. Nature 372: 669\u2013672.","author":"R Adolphs","year":"1994"},{"key":"ref52","article-title":"A mechanism for impaired fear recognition after amygdala damage. Nature 433: 68\u201372.","author":"R Adolphs","year":"2005"},{"key":"ref53","article-title":"Contributions of the amygdala to reward expectancy and choice signals in human prefrontal cortex. Neuron 55: 545\u2013555.","author":"AN Hampton","year":"2007"},{"key":"ref54","article-title":"Oxytocin enhances amygdala-dependent, socially reinforced learning and emotional empathy in humans. The Journal of Neuroscience 30: 4999\u20135007.","author":"R Hurlemann","year":"2010"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1016\/j.neuropsychologia.2006.08.027","article-title":"Amygdala control of emotion-induced forgetting and remembering: evidence from Urbach-Wiethe disease.","volume":"45","author":"R Hurlemann","year":"2007","journal-title":"Neuropsychologia"},{"key":"ref56","article-title":"The human amygdala and the induction and experience of fear. Current Biology 21: 34\u201338.","author":"JS Feinstein","year":"2011"},{"key":"ref57","article-title":"Reduced 5-HT(2A) receptor signaling following selective bilateral amygdala damage. Social Cognitive and Affective Neuroscience 4: 79\u201384.","author":"R Hurlemann","year":"2009"},{"key":"ref58","article-title":"Personal space regulation by the human amygdala. Nature Neuroscience 12: 1226\u20131227.","author":"DP Kennedy","year":"2009"},{"key":"ref59","article-title":"Amygdala damage impairs emotional memory for gist but not details of complex stimuli. Nature Neuroscience 8: 512\u2013518.","author":"R Adolphs","year":"2005"},{"key":"ref60","article-title":"Is the human amygdala critical for the subjective experience of emotion? Evidence of intact dispositional affect in patients with amygdala lesions. Journal of Cognitive Neuroscience 14: 709\u2013720.","author":"AK Anderson","year":"2002"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"1775","DOI":"10.1093\/brain\/119.5.1775","article-title":"Paradoxical functional facilitation in brain-behaviour research. A critical review.","volume":"119","author":"N Kapur","year":"1996","journal-title":"Brain"},{"key":"ref62","article-title":"Functional connectivity of the human amygdala using resting state fMRI. NeuroImage 45: 614\u2013626.","author":"AK Roy","year":"2009"},{"key":"ref63","article-title":"Two views of brain function. Trends in Cognitive Sciences 14: 180\u2013190.","author":"ME Raichle","year":"2010"},{"key":"ref64","article-title":"Working Memory, its Executive Functions, and the Emergence of Modern Thinking. Cambridge Archaeological Journal 15: 5\u201326.","author":"FL Coolidge","year":"2005"},{"key":"ref65","article-title":"Direct and indirect pathways from the amygdala to the frontal lobe in rhesus monkeys. The Journal of Comparative Neurology 198: 121\u2013136.","author":"LJ Porrino","year":"1981"},{"key":"ref66","article-title":"Overlapping neural systems mediating extinction, reversal and regulation of fear. Trends in Cognitive Sciences 14: 268\u2013276.","author":"D Schiller","year":"2010"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0038116","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,29]],"date-time":"2019-06-29T12:27:32Z","timestamp":1561811252000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0038116"}},"subtitle":[],"editor":[{"given":"Friedemann","family":"Paul","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2012,6,8]]},"references-count":66,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2012,6,8]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0038116","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,6,8]]}}}