{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T13:30:01Z","timestamp":1762176601700},"reference-count":33,"publisher":"Public Library of Science (PLoS)","issue":"6","license":[{"start":{"date-parts":[[2012,6,4]],"date-time":"2012-06-04T00:00:00Z","timestamp":1338768000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0038241","type":"journal-article","created":{"date-parts":[[2012,6,5]],"date-time":"2012-06-05T07:03:51Z","timestamp":1338879831000},"page":"e38241","update-policy":"http:\/\/dx.doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":11,"title":["Novel Evidence of HBV Recombination in Family Cluster Infections in Western China"],"prefix":"10.1371","volume":"7","author":[{"given":"Bin","family":"Zhou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhanhui","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hua","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuhito","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masashi","family":"Mizokami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinlin","family":"Hou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2012,6,4]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"2498","DOI":"10.1128\/JVI.64.6.2498-2504.1990","article-title":"Phosphoprotein and nucleocapsid protein evolution of vesicular stomatitis virus New Jersey.","volume":"64","author":"PA Bilsel","year":"1990","journal-title":"J Virol"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"2575","DOI":"10.1099\/0022-1317-69-10-2575","article-title":"Typing hepatitis B virus by homology in nucleotide sequence: comparison of surface antigen subtypes.","volume":"10)","author":"H Okamoto","year":"1988","journal-title":"J Gen Virol 69 (Pt"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1099\/0022-1317-73-5-1201","article-title":"Comparison of the amino acid sequences of nine different serotypes of hepatitis B surface antigen and genomic classification of the corresponding hepatitis B virus strains.","volume":"5)","author":"H Norder","year":"1992","journal-title":"J Gen Virol 73 (Pt"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1006\/viro.1998.9126","article-title":"The hepatitis B virus seroconversion to anti-HBe is frequently associated with HBV genotype changes and selection of preS2-defective particles in chronically infected children.","volume":"245","author":"PR Gerner","year":"1998","journal-title":"Virology"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1002\/hep.21342","article-title":"Mixed hepatitis B virus genotype infections: the more, the worse?","volume":"44","author":"CJ Liu","year":"2006","journal-title":"Hepatology"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"1674","DOI":"10.1002\/jmv.20985","article-title":"High prevalence of occult hepatitis B virus infection in Taiwanese intravenous drug users.","volume":"79","author":"CL Lin","year":"2007","journal-title":"J Med Virol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1099\/vir.0.80771-0","article-title":"A new intertype recombinant between genotypes C and D of hepatitis B virus identified in China.","volume":"86","author":"Z Wang","year":"2005","journal-title":"J Gen Virol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"e18708","DOI":"10.1371\/journal.pone.0018708","article-title":"Geographical and ethnic distribution of the HBV C\/D recombinant on the Qinghai-Tibet Plateau.","volume":"6","author":"B Zhou","year":"2011","journal-title":"PLoS One"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"3132","DOI":"10.3748\/wjg.v10.i21.3132","article-title":"A novel hepatitis B virus genotyping system by using restriction fragment length polymorphism patterns of S gene amplicons.","volume":"10","author":"GB Zeng","year":"2004","journal-title":"World J Gastroenterol"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1099\/0022-1317-82-4-883","article-title":"A novel variant genotype C of hepatitis B virus identified in isolates from Australian Aborigines: complete genome sequence and phylogenetic relatedness.","volume":"82","author":"F Sugauchi","year":"2001","journal-title":"J Gen Virol"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"5437","DOI":"10.1128\/JVI.69.9.5437-5444.1995","article-title":"A novel method for efficient amplification of whole hepatitis B virus genomes permits rapid functional analysis and reveals deletion mutants in immunosuppressed patients.","volume":"69","author":"S Gunther","year":"1995","journal-title":"J Virol"},{"key":"ref12","first-page":"925","article-title":"Epidemiologic and virologic characteristics of hepatitis B virus genotype B having the recombination with genotype C. Gastroenterology","volume":"124","author":"F Sugauchi","year":"2003"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1093\/bioinformatics\/16.6.562","article-title":"RDP: detection of recombination amongst aligned sequences.","volume":"16","author":"D Martin","year":"2000","journal-title":"Bioinformatics"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"11827","DOI":"10.1128\/JVI.01100-06","article-title":"Recombination patterns in aphthoviruses mirror those found in other picornaviruses.","volume":"80","author":"L Heath","year":"2006","journal-title":"J Virol"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"2535","DOI":"10.1099\/0022-1317-80-10-2535","article-title":"Evolutionary aspects of recombination in RNA viruses.","volume":"10)","author":"M Worobey","year":"1999","journal-title":"J Gen Virol 80 (Pt"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1099\/vir.0.018127-0","article-title":"A novel hepatitis B virus (HBV) subgenotype D (D8) strain, resulting from recombination between genotypes D and E, is circulating in Niger along with HBV\/E strains.","volume":"91","author":"CM Abdou","year":"2010","journal-title":"J Gen Virol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1002\/jmv.21775","article-title":"Genotype X\/C recombinant (putative genotype I) of hepatitis B virus is rare in Hanoi, Vietnam\u2013genotypes B4 and C1 predominate.","volume":"82","author":"TB Phung","year":"2010","journal-title":"J Med Virol"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1099\/vir.0.026666-0","article-title":"A complex hepatitis B virus (X\/C) recombinant is common in Long An county, Guangxi and may have originated in southern China.","volume":"92","author":"ZL Fang","year":"2011","journal-title":"J Gen Virol"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1128\/JCM.00867-10","article-title":"Hepatitis B virus (HBV) infection and recombination between HBV genotypes D and E in asymptomatic blood donors from Khartoum, Sudan.","volume":"49","author":"S Mahgoub","year":"2011","journal-title":"J Clin Microbiol"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"2267","DOI":"10.1099\/0022-1317-81-9-2267","article-title":"An aberrant genotype revealed in recombinant hepatitis B virus strains from Vietnam.","volume":"81","author":"C Hannoun","year":"2000","journal-title":"J Gen Virol"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/0042-6822(91)90795-D","article-title":"Random nature of coronavirus RNA recombination in the absence of selection pressure.","volume":"185","author":"LR Banner","year":"1991","journal-title":"Virology"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"6131","DOI":"10.1128\/JVI.76.12.6131-6137.2002","article-title":"Characteristics of hepatitis B virus isolates of genotype G and their phylogenetic differences from the other six genotypes (A through F).","volume":"76","author":"H Kato","year":"2002","journal-title":"J Virol"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1002\/hep.21345","article-title":"Influence of hepatitis B virus genotypes on the intra- and extracellular expression of viral DNA and antigens.","volume":"44","author":"M Sugiyama","year":"2006","journal-title":"Hepatology"},{"key":"ref24","first-page":"929","article-title":"Early dynamics of hepatitis B virus in chimeric mice carrying human hepatocytes monoinfected or coinfected with genotype G. Hepatology","volume":"45","author":"M Sugiyama","year":"2007"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"2203","DOI":"10.1099\/vir.0.81752-0","article-title":"Identification of Hepatitis B virus putative intergenotype recombinants by using fragment typing.","volume":"87","author":"J Yang","year":"2006","journal-title":"J Gen Virol"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"5657","DOI":"10.1128\/JVI.02556-07","article-title":"New complex recombinant genotype of hepatitis B virus identified in Vietnam.","volume":"82","author":"TT Tran","year":"2008","journal-title":"J Virol"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"15467","DOI":"10.1128\/JVI.79.24.15467-15476.2005","article-title":"Recombination in the genesis and evolution of hepatitis B virus genotypes.","volume":"79","author":"P Simmonds","year":"2005","journal-title":"J Virol"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/S0378-1119(00)00424-8","article-title":"Homologous recombination between different genotypes of hepatitis B virus.","volume":"260","author":"V Morozov","year":"2000","journal-title":"Gene"},{"key":"ref29","first-page":"441","article-title":"Hepatitis B virus DNA in serum of healthy black African adults positive for hepatitis B surface antibody alone: possible association with recombination between genotypes A and D. J Med Virol","volume":"64","author":"WK Owiredu","year":"2001"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"2047","DOI":"10.1099\/vir.0.80922-0","article-title":"A new subtype (subgenotype) Ac (A3) of hepatitis B virus and recombination between genotypes A and E in Cameroon.","volume":"86","author":"F Kurbanov","year":"2005","journal-title":"J Gen Virol"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"5657","DOI":"10.1128\/JVI.02556-07","article-title":"New complex recombinant genotype of hepatitis B virus identified in Vietnam.","volume":"82","author":"TT Tran","year":"2008","journal-title":"J Virol"},{"key":"ref32","first-page":"10538","article-title":"A genetic variant of hepatitis B virus divergent from known human and ape genotypes isolated from a Japanese patient and provisionally assigned to new genotype J. J Virol","volume":"83","author":"K Tatematsu","year":"2009"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"5985","DOI":"10.1128\/JVI.76.12.5985-5992.2002","article-title":"Hepatitis B virus of genotype B with or without recombination with genotype C over the precore region plus the core gene.","volume":"76","author":"F Sugauchi","year":"2002","journal-title":"J Virol"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0038241","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,8]],"date-time":"2020-07-08T10:39:23Z","timestamp":1594204763000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0038241"}},"subtitle":[],"editor":[{"given":"Darren P.","family":"Martin","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2012,6,4]]},"references-count":33,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2012,6,4]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0038241","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,6,4]]}}}