{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,6,2]],"date-time":"2024-06-02T16:50:43Z","timestamp":1717347043261},"reference-count":55,"publisher":"Public Library of Science (PLoS)","issue":"7","license":[{"start":{"date-parts":[[2012,7,24]],"date-time":"2012-07-24T00:00:00Z","timestamp":1343088000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0041420","type":"journal-article","created":{"date-parts":[[2012,7,24]],"date-time":"2012-07-24T21:22:43Z","timestamp":1343164963000},"page":"e41420","update-policy":"http:\/\/dx.doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":20,"title":["Evidence of Prognostic Relevant Expression Profiles of Heat-Shock Proteins and Glucose-Regulated Proteins in Oesophageal Adenocarcinomas"],"prefix":"10.1371","volume":"7","author":[{"given":"Julia","family":"Slotta-Huspenina","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"Berg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karina","family":"Bauer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia","family":"Wolff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katharina","family":"Malinowsky","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lukas","family":"Bauer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enken","family":"Drecoll","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcus","family":"Bettstetter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcus","family":"Feith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Axel","family":"Walch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heinz","family":"H\u00f6fler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karl-Friedrich","family":"Becker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rupert","family":"Langer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2012,7,24]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1245\/ASO.2005.12.025","article-title":"Adenocarcinoma of the esophagus and cardia: a review of the disease and its treatment.","volume":"13","author":"SR DeMeester","year":"2006","journal-title":"Ann Surg Oncol"},{"key":"ref2","first-page":"69","article-title":"Global cancer statistics.","volume":"61","author":"A Jemal","year":"2011","journal-title":"CA: A Cancer Journal for Clinicians"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1056\/NEJMoa055531","article-title":"Perioperative chemotherapy versus surgery alone for resectable gastroesophageal cancer.","volume":"355","author":"D Cunningham","year":"2006","journal-title":"N Engl J Med"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"1555","DOI":"10.1038\/modpathol.2009.123","article-title":"Prognostic significance of histopathological tumor regression after neoadjuvant chemotherapy in esophageal adenocarcinomas.","volume":"22","author":"R Langer","year":"2009","journal-title":"Mod Pathol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1002\/bjs.4575","article-title":"Neoadjuvant therapy for oesophagogastric cancer.","volume":"91","author":"F Lordick","year":"2004","journal-title":"Br J Surg"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1097\/01.sla.0000186170.38348.7b","article-title":"Histomorphologic tumor regression and lymph node metastases determine prognosis following neoadjuvant radiochemotherapy for esophageal cancer: implications for response classification.","volume":"242","author":"PM Schneider","year":"2005","journal-title":"Ann Surg"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"4347","DOI":"10.1200\/JCO.2005.04.9445","article-title":"Prognostic Factors in Adenocarcinoma of the Esophagus or Gastroesophageal Junction.","volume":"24","author":"SM Lagarde","year":"2006","journal-title":"J Clin Oncol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"8279","DOI":"10.1158\/1078-0432.CCR-08-0679","article-title":"Protein expression profiling in esophageal adenocarcinoma patients indicates association of heat-shock protein 27 expression and chemotherapy response.","volume":"14","author":"R Langer","year":"2008","journal-title":"Clin Cancer Res"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"e23985","DOI":"10.1371\/journal.pone.0023985","article-title":"Discovery of new molecular subtypes in oesophageal adenocarcinoma.","volume":"6","author":"D Berg","year":"2011","journal-title":"PLoS One"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1186\/1756-8722-3-40","article-title":"The anti-myeloma activity of a novel purine scaffold HSP90 inhibitor PU-H71 is via inhibition of both HSP90A and HSP90B1.","volume":"3","author":"SZ Usmani","year":"2010","journal-title":"J Hematol Oncol"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1111\/j.1365-2141.2011.08671.x","article-title":"Inducing apoptosis in chemotherapy-resistant B-lineage acute lymphoblastic leukaemia cells by targeting HSPA5, a master regulator of the anti-apoptotic unfolded protein response signalling network.","volume":"153","author":"FM Uckun","year":"2011","journal-title":"Br J Haematol"},{"key":"ref12","article-title":"MSDaPl (Mass Spectrometry Data Platform): A Proteomics Data Management Platform.","author":"V Sharma","year":"2012"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.canlet.2009.07.010","article-title":"Geldanamycin and its anti-cancer activities.","volume":"290","author":"Y Fukuyo","year":"2010","journal-title":"Cancer Lett"},{"key":"ref14","article-title":"Targeting heat shock proteins in cancer.","author":"G Jego","year":"2010"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1002\/path.2107","article-title":"Quantitative protein analysis from formalin-fixed tissues: implications for translational clinical research and nanoscale molecular diagnosis.","volume":"211","author":"KF Becker","year":"2007","journal-title":"J Pathol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"e16353","DOI":"10.1371\/journal.pone.0016353","article-title":"Successful protein extraction from over-fixed and long-term stored formalin-fixed tissues.","volume":"6","author":"C Wolff","year":"2011","journal-title":"PLoS One"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1002\/path.1958","article-title":"Array-based proteomics: mapping of protein circuitries for diagnostics, prognostics, and therapy guidance in cancer.","volume":"208","year":"2006","journal-title":"J Pathol"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"1796","DOI":"10.1038\/nprot.2008.179","article-title":"Reverse-phase protein lysate microarrays for cell signaling analysis.","volume":"3","author":"B Spurrier","year":"2008","journal-title":"Nat Protoc"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"4301","DOI":"10.1038\/sj.onc.1202790","article-title":"Tumour-associated E-cadherin mutations alter cellular morphology, decrease cellular adhesion and increase cellular motility.","volume":"18","author":"G Handschuh","year":"1999","journal-title":"Oncogene"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1186\/1471-2407-8-70","article-title":"Expression and clinical significance of glucose regulated proteins GRP78 (BiP) and GRP94 (GP96) in human adenocarcinomas of the esophagus.","volume":"8","author":"R Langer","year":"2008","journal-title":"BMC Cancer"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/S0002-9440(10)63985-5","article-title":"Quantitative gene expression analysis in microdissected archival formalin-fixed and paraffin-embedded tumor tissue.","volume":"158","author":"K Specht","year":"2001","journal-title":"Am J Pathol"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"14863","DOI":"10.1073\/pnas.95.25.14863","article-title":"Cluster analysis and display of genome-wide expression patterns.","volume":"95","author":"MB Eisen","year":"1998","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1146\/annurev.ge.22.120188.003215","article-title":"The heat-shock proteins.","volume":"22","author":"S Lindquist","year":"1988","journal-title":"Annu Rev Genet"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"518","DOI":"10.4161\/cc.8.4.7583","article-title":"Death by chaperone: HSP90, HSP70 or both?","volume":"8","author":"MV Powers","year":"2009","journal-title":"Cell Cycle"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"741","DOI":"10.4161\/cbt.5.7.2970","article-title":"Glucose regulated proteins in cancer progression, drug resistance and immunotherapy.","volume":"5","author":"Y Fu","year":"2006","journal-title":"Cancer Biol Ther"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"3496","DOI":"10.1158\/0008-5472.CAN-07-0325","article-title":"GRP78 induction in cancer: therapeutic and prognostic implications.","volume":"67","author":"AS Lee","year":"2007","journal-title":"Cancer Res"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.tibs.2006.01.006","article-title":"Heat shock proteins in cancer: chaperones of tumorigenesis.","volume":"31","author":"SK Calderwood","year":"2006","journal-title":"Trends Biochem Sci"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1379\/CSC-99r.1","article-title":"Heat shock proteins in cancer: diagnostic, prognostic, predictive, and treatment implications.","volume":"10","author":"DR Ciocca","year":"2005","journal-title":"Cell Stress Chaperones"},{"key":"ref29","first-page":"89","article-title":"Heat shock proteins in oncology: Diagnostic biomarkers or therapeutic targets?","volume":"1816","author":"AA Khalil","year":"2011","journal-title":"Biochim Biophys Acta"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1136\/gut.2009.196626","article-title":"Low molecular weight heat shock protein HSP27 is a prognostic indicator in rectal cancer but not colon cancer.","volume":"59","author":"EM Tweedle","year":"2010","journal-title":"Gut"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1002\/cncr.22864","article-title":"Patient survival by Hsp70 membrane phenotype: association with different routes of metastasis.","volume":"110","author":"K Pfister","year":"2007","journal-title":"Cancer"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"212537","DOI":"10.1155\/2010\/212537","article-title":"Correlation between clinicopathology and expression of heat shock protein 72 and glycoprotein 96 in human esophageal squamous cell carcinoma.","volume":"2010","author":"X Wang","year":"2010","journal-title":"Clin Dev Immunol"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1038\/sj.bjc.6604855","article-title":"Hsp90 is expressed and represents a therapeutic target in human oesophageal cancer using the inhibitor 17-allylamino-17-demethoxygeldanamycin.","volume":"100","author":"X Wu","year":"2009","journal-title":"Br J Cancer"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1245\/s10434-010-1128-7","article-title":"Correlation between gp96 expression and the surgical outcome in patients with esophageal squamous cell carcinoma.","volume":"18","author":"Y Akutsu","year":"2011","journal-title":"Ann Surg Oncol"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1002\/path.2795","article-title":"GRP78 up-regulation is associated with androgen receptor status, Hsp70-Hsp90 client proteins and castrate-resistant prostate cancer.","volume":"223","author":"SS Tan","year":"2011","journal-title":"J Pathol"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"2072","DOI":"10.3748\/wjg.v11.i14.2072","article-title":"Expression of heat shock proteins (HSP27, HSP60, HSP70, HSP90, GRP78, GRP94) in hepatitis B virus-related hepatocellular carcinomas and dysplastic nodules.","volume":"11","author":"SO Lim","year":"2005","journal-title":"World J Gastroenterol"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"e27718","DOI":"10.1371\/journal.pone.0027718","article-title":"The proteomics of colorectal cancer: identification of a protein signature associated with prognosis.","volume":"6","author":"D O\u2019Dwyer","year":"2011","journal-title":"PLoS One"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"18947","DOI":"10.1074\/jbc.274.27.18947","article-title":"Regulation of Hsp27 oligomerization, chaperone function, and protective activity against oxidative stress\/tumor necrosis factor alpha by phosphorylation.","volume":"274","author":"T Rogalla","year":"1999","journal-title":"J Biol Chem"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.canlet.2009.07.010","article-title":"Geldanamycin and its anti-cancer activities.","volume":"290","author":"Y Fukuyo","year":"2010","journal-title":"Cancer letters"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1158\/1078-0432.CCR-08-0132","article-title":"Heat Shock Protein 90 as a Drug Target: Some Like It Hot.","volume":"15","author":"U Banerji","year":"2009","journal-title":"Clinical Cancer Research"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"1542","DOI":"10.4161\/cc.9.8.11204","article-title":"Targeting HSP70: the second potentially druggable heat shock protein and molecular chaperone?","volume":"9","author":"MV Powers","year":"2010","journal-title":"Cell Cycle"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/1559-0275-8-11","article-title":"Functional proteomics can define prognosis and predict pathologic complete response in patients with breast cancer.","volume":"8","author":"A Gonzalez-Angulo","year":"2011","journal-title":"Clinical Proteomics"},{"key":"ref43","article-title":"Signalling networks associated with urokinase-type plasminogen activator (uPA) and its inhibitor PAI-1 in breast cancer tissues: new insights from protein microarray analysis.","author":"C Wolff","year":"2010"},{"key":"ref44","doi-asserted-by":"crossref","DOI":"10.1097\/JTO.0b013e3181f2a266","article-title":"Proteomic Profiling Identifies Pathways Dysregulated in Non-small Cell Lung Cancer and an Inverse Association of AMPK and Adhesion Pathways with Recurrence.","author":"M Nanjundan","year":"2010"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"e26459","DOI":"10.1371\/journal.pone.0026459","article-title":"Identification of direct target engagement biomarkers for kinase-targeted therapeutics.","volume":"6","author":"CP Paweletz","year":"2011","journal-title":"PLoS One"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"2512","DOI":"10.1158\/1535-7163.MCT-06-0334","article-title":"Reverse phase protein array: validation of a novel proteomic technology and utility for analysis of primary leukemia specimens and hematopoietic stem cells.","volume":"5","author":"R Tibes","year":"2006","journal-title":"Molecular Cancer Therapeutics"},{"key":"ref47","first-page":"797","article-title":"Excavation of a buried treasure\u2013DNA, mRNA, miRNA and protein analysis in formalin fixed, paraffin embedded tissues.","volume":"26","author":"R Klopfleisch","year":"2011","journal-title":"Histol Histopathol"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1007\/978-1-61779-286-1_9","article-title":"Producing reverse phase protein microarrays from formalin-fixed tissues.","volume":"785","author":"C Wolff","year":"2011","journal-title":"Methods Mol Biol"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1007\/978-1-61779-286-1_8","article-title":"Use of formalin-fixed and paraffin-embedded tissues for diagnosis and therapy in routine clinical settings.","volume":"785","author":"D Berg","year":"2011","journal-title":"Methods Mol Biol"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.ejca.2009.10.016","article-title":"Molecular profiling of signalling pathways in formalin-fixed and paraffin-embedded cancer tissues.","volume":"46","author":"D Berg","year":"2010","journal-title":"Eur J Cancer"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1002\/cncy.20147","article-title":"Biospecimen reporting for improved study quality (BRISQ).","volume":"119","author":"HM Moore","year":"2011","journal-title":"Cancer Cytopathol"},{"key":"ref52","article-title":"Documenting biospecimen conditions in reports of studies.","author":"JA Robb","year":"2008"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1097\/SLA.0b013e318216f449","article-title":"Significance of histopathological tumor regression after neoadjuvant chemotherapy in gastric adenocarcinomas: a summary of 480 cases.","volume":"253","author":"K Becker","year":"2011","journal-title":"Ann Surg"},{"key":"ref54","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1016\/j.lfs.2006.12.005","article-title":"Proteomics in clinical interventions: achievements and limitations in biomarker development.","volume":"80","author":"A Sinha","year":"2007","journal-title":"Life Sci"},{"key":"ref55","doi-asserted-by":"crossref","DOI":"10.1007\/s13402-012-0079-3","article-title":"High HSP27 and HSP70 expression levels are independent adverse prognostic factors in primary resected colon cancer.","author":"K Bauer","year":"2012"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0041420","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,9]],"date-time":"2020-05-09T08:39:12Z","timestamp":1589013552000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0041420"}},"subtitle":[],"editor":[{"given":"Michael","family":"Sherman","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2012,7,24]]},"references-count":55,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2012,7,24]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0041420","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,7,24]]}}}