{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T05:51:48Z","timestamp":1717221108699},"reference-count":43,"publisher":"Public Library of Science (PLoS)","issue":"7","license":[{"start":{"date-parts":[[2012,7,23]],"date-time":"2012-07-23T00:00:00Z","timestamp":1343001600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0041573","type":"journal-article","created":{"date-parts":[[2012,7,23]],"date-time":"2012-07-23T21:29:26Z","timestamp":1343078966000},"page":"e41573","update-policy":"http:\/\/dx.doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":9,"title":["Removing N-Terminal Sequences in Pre-S1 Domain Enhanced Antibody and B-Cell Responses by an HBV Large Surface Antigen DNA Vaccine"],"prefix":"10.1371","volume":"7","author":[{"given":"Guohong","family":"Ge","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shixia","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yaping","family":"Han","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chunhua","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shan","family":"Lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zuhu","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2012,7,23]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1038\/317489a0","article-title":"The hepatitis B virus.","volume":"317","author":"P Tiollais","year":"1985","journal-title":"Nature"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1182\/blood.V27.3.297.297","article-title":"Further studies on a \u201cnew\u201d human isoprecipitin system (Australia antigen).","volume":"27","author":"HJ Alter","year":"1966","journal-title":"Blood"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"6266","DOI":"10.1016\/j.vaccine.2008.09.056","article-title":"The global impact of vaccination against hepatitis B: a historical overview.","volume":"26","author":"AR Zanetti","year":"2008","journal-title":"Vaccine"},{"key":"ref4","article-title":"Healthcare stumbling in RI's Hepatitis fight.","year":"2011"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1128\/MMBR.64.1.51-68.2000","article-title":"Hepatitis B virus biology.","volume":"64","author":"C Seeger","year":"2000","journal-title":"Microbiol Mol Biol Rev"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1016\/S0140-6736(76)93023-3","article-title":"Immunisation against hepatitis B in man.","volume":"1","author":"P Maupas","year":"1976","journal-title":"Lancet"},{"key":"ref7","first-page":"98","article-title":"Vaccination against hepatitis B: the Chinese experience.","volume":"122","author":"YH Zhou","year":"2009","journal-title":"Chin Med J (Engl)"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1038\/307178a0","article-title":"Human hepatitis B vaccine from recombinant yeast.","volume":"307","author":"WJ McAleer","year":"1984","journal-title":"Nature"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/0264-410X(95)00185-4","article-title":"Safety and immunogenicity of a novel mammalian cell-derived recombinant hepatitis B vaccine containing Pre-S1 and Pre-S2 antigens in children.","volume":"14","author":"R Raz","year":"1996","journal-title":"Vaccine"},{"key":"ref10","first-page":"31","article-title":"Recombinant yeast hepatitis B vaccine compared with plasma-derived vaccine: immunogenicity and effect of a booster dose.","author":"M Davidson","year":"1986"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"2781","DOI":"10.1016\/j.vaccine.2006.01.007","article-title":"Comparative immunogenicity of a PreS\/S hepatitis B vaccine in non- and low responders to conventional vaccine.","volume":"24","author":"P Rendi-Wagner","year":"2006","journal-title":"Vaccine"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"356","DOI":"10.7326\/0003-4819-105-3-356","article-title":"Nonresponsiveness to hepatitis B vaccine in health care workers. Results of revaccination and genetic typings.","volume":"105","author":"DE Craven","year":"1986","journal-title":"Ann Intern Med"},{"key":"ref13","first-page":"631","article-title":"HBV-specific T-cell responses in healthy seronegative sexual partners of patients with chronic HBV infection.","volume":"17","author":"J Wiegand","year":"2010","journal-title":"J Viral Hepat"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1203\/00006450-199209000-00002","article-title":"Mutations within the S gene of hepatitis B virus transmitted from mothers to babies immunized with hepatitis B immune globulin and vaccine.","volume":"32","author":"H Okamoto","year":"1992","journal-title":"Pediatr Res"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"1374","DOI":"10.1093\/infdis\/169.6.1374","article-title":"Breakthrough infections and identification of a viral variant in Gambian children immunized with hepatitis B vaccine.","volume":"169","author":"M Fortuin","year":"1994","journal-title":"J Infect Dis"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1017\/S0950268800003605","article-title":"Predictions of the emergence of vaccine-resistant hepatitis B in The Gambia using a mathematical model.","volume":"124","author":"JN Wilson","year":"2000","journal-title":"Epidemiol Infect"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1046\/j.1365-2893.1998.0050s2031.x","article-title":"Mechanism of emergence of hepatitis B virus escape variants: approaches to prevention.","volume":"5","author":"HC Thomas","year":"1998","journal-title":"J Viral Hepat"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1084\/jem.168.1.293","article-title":"Human T cell response to the surface antigen of hepatitis B virus (HBsAg). Endosomal and nonendosomal processing pathways are accessible to both endogenous and exogenous antigen.","volume":"168","author":"Y Jin","year":"1988","journal-title":"J Exp Med"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1172\/JCI114299","article-title":"The preS1 antigen of hepatitis B virus is highly immunogenic at the T cell level in man.","volume":"84","author":"C Ferrari","year":"1989","journal-title":"J Clin Invest"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"9786","DOI":"10.1128\/JVI.79.15.9786-9798.2005","article-title":"Mapping of the hepatitis B virus pre-S1 domain involved in receptor recognition.","volume":"79","author":"A Barrera","year":"2005","journal-title":"J Virol"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"1989","DOI":"10.1128\/JVI.01902-09","article-title":"Fine mapping of pre-S sequence requirements for hepatitis B virus large envelope protein-mediated receptor interaction.","volume":"84","author":"A Schulze","year":"2010","journal-title":"J Virol"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1016\/0167-5699(88)91239-X","article-title":"T- and B-cell recognition of hepatitis B viral antigens.","volume":"9","author":"DR Milich","year":"1988","journal-title":"Immunology Today"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"9174","DOI":"10.1073\/pnas.83.23.9174","article-title":"A synthetic peptide vaccine involving the product of the pre-S(2) region of hepatitis B virus DNA: protective efficacy in chimpanzees.","volume":"83","author":"Y Itoh","year":"1986","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/0264-410X(89)90235-1","article-title":"Antibodies to synthetic peptides from the preS1 region of the hepatitis B virus (HBV) envelope (env) protein are virus-neutralizing and protective.","volume":"7","author":"AR Neurath","year":"1989","journal-title":"Vaccine"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.1016\/S0140-6736(88)92237-4","article-title":"ANTIBODY RESPONSE TO PRE-S2 AND HEPATITIS B VIRUS INDUCED LIVER DAMAGE.","volume":"331","author":"A Alberti","year":"1988","journal-title":"The Lancet"},{"key":"ref26","first-page":"PI10","article-title":"Presence of anti-preS1, anti-preS2, and anti-HBs antibodies in newborns immunized with Bio-Hep-B vaccine.","volume":"10","author":"K Madalinski","year":"2004","journal-title":"Med Sci Monit"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"7288","DOI":"10.1016\/j.vaccine.2010.08.081","article-title":"Profiles of B and T cell immune responses elicited by different forms of the hepatitis B virus surface antigen.","volume":"28","author":"M Shen","year":"2010","journal-title":"Vaccine"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/0042-6822(91)90510-I","article-title":"The C-terminal half of the preS1 region is essential for the secretion of human hepatitis B virus large S protein devoid of the N-terminal retention sequence.","volume":"181","author":"XM Yu","year":"1991","journal-title":"Virology"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1128\/JVI.60.2.337-344.1986","article-title":"Hepatitis B virus large surface protein is not secreted but is immunogenic when selectively expressed by recombinant vaccinia virus.","volume":"60","author":"KC Cheng","year":"1986","journal-title":"J Virol"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"3813","DOI":"10.1128\/JVI.65.7.3813-3820.1991","article-title":"Mutational analysis of hepatitis B surface antigen particle assembly and secretion.","volume":"65","author":"V Bruss","year":"1991","journal-title":"J Virol"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1006\/viro.1995.1546","article-title":"A C-terminal PreS1 sequence is sufficient to retain hepatitis B virus L protein in 293 cells.","volume":"213","author":"A Gallina","year":"1995","journal-title":"Virology"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"4459","DOI":"10.1128\/MCB.9.10.4459","article-title":"Novel N-terminal amino acid sequence required for retention of a hepatitis B virus glycoprotein in the endoplasmic reticulum.","volume":"9","author":"K Kuroki","year":"1989","journal-title":"Mol Cell Biol"},{"key":"ref33","first-page":"633","article-title":"\u4e00\u4e2a\u80fd\u5206\u6ccc\u51fa\u54fa\u4e73\u52a8\u7269\u7ec6\u80de\u7684HBV \u8868\u9762\u6297\u539f\u5927\u86cb\u767d. \u4e2d\u56fd\u79d1\u5b66B \u8f91 06: 633-638. X Yu, H Wang and Z Li (1991) Production of HBs large antigen in mammalian cells.","volume":"06","year":"1911","journal-title":"China Science Volume B"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"2100","DOI":"10.1016\/j.vaccine.2008.02.033","article-title":"The relative immunogenicity of DNA vaccines delivered by the intramuscular needle injection, electroporation and gene gun methods.","volume":"26","author":"S Wang","year":"2008","journal-title":"Vaccine"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"5145","DOI":"10.1016\/j.vaccine.2008.03.072","article-title":"The ability of Hepatitis B surface antigen DNA vaccine to elicit cell-mediated immune responses, but not antibody responses, was affected by the deglysosylation of S antigen.","volume":"26","author":"Y Xing","year":"2008","journal-title":"Vaccine"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.jhep.2009.02.017","article-title":"EASL clinical practice guidelines on the management of chronic hepatitis B: the need for liver biopsy.","volume":"51","author":"GV Papatheodoridis","year":"2009","journal-title":"J Hepatol"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.patbio.2010.01.006","article-title":"Hepatitis B vaccines: protective efficacy and therapeutic potential.","volume":"58","author":"ML Michel","year":"2010","journal-title":"Pathol Biol (Paris)"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"12443","DOI":"10.1128\/JVI.01594-09","article-title":"The pre-S1 and antigenic loop infectivity determinants of the hepatitis B virus envelope proteins are functionally independent.","volume":"83","author":"Y Le Duff","year":"2009","journal-title":"J Virol"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1038\/nbt1389","article-title":"Prevention of hepatitis B virus infection in vivo by entry inhibitors derived from the large envelope protein.","volume":"26","author":"J Petersen","year":"2008","journal-title":"Nat Biotechnol"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"11819","DOI":"10.1128\/JVI.01026-09","article-title":"The first transmembrane domain of the hepatitis B virus large envelope protein is crucial for infectivity.","volume":"83","author":"C Lepere-Douard","year":"2009","journal-title":"J Virol"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"812","DOI":"10.3858\/emm.2009.41.11.087","article-title":"Modulation of protective immunity against herpes simplex virus via mucosal genetic co-transfer of DNA vaccine with beta2-adrenergic agonist.","volume":"41","author":"SB Kim","year":"2009","journal-title":"Exp Mol Med"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"8392","DOI":"10.1073\/pnas.90.18.8392","article-title":"Production of high-titer helper-free retroviruses by transient transfection.","volume":"90","author":"WS Pear","year":"1993","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"11628","DOI":"10.1128\/JVI.01065-06","article-title":"Hemagglutinin (HA) proteins from H1 and H3 serotypes of influenza A viruses require different antigen designs for the induction of optimal protective antibody responses as studied by codon-optimized HA DNA vaccines.","volume":"80","author":"S Wang","year":"2006","journal-title":"J Virol"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0041573","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,11]],"date-time":"2020-07-11T10:38:59Z","timestamp":1594463939000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0041573"}},"subtitle":[],"editor":[{"given":"Xu","family":"Yu","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2012,7,23]]},"references-count":43,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2012,7,23]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0041573","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,7,23]]}}}