{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T15:37:13Z","timestamp":1790696233209,"version":"4.1.0"},"reference-count":50,"publisher":"Public Library of Science (PLoS)","issue":"10","license":[{"start":{"date-parts":[[2012,10,29]],"date-time":"2012-10-29T00:00:00Z","timestamp":1351468800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0046740","type":"journal-article","created":{"date-parts":[[2012,10,29]],"date-time":"2012-10-29T22:04:33Z","timestamp":1351548273000},"page":"e46740","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":80,"title":["Adipokines in Psoriatic Arthritis Patients: The Correlations with Osteoclast Precursors and Bone Erosions"],"prefix":"10.1371","volume":"7","author":[{"given":"Yu","family":"Xue","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingqing","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haiyan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiyun","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yinda","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xue","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ning","family":"Kong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoxia","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xue","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiguo","family":"Wan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hejian","family":"Zou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2012,10,29]]},"reference":[{"key":"ref1","first-page":"2645","article-title":"Operational definitions and observer reliability of the plain radiographic features of psoriatic arthritis","volume":"30","author":"WJ Taylor","year":"2003","journal-title":"J Rheumatol"},{"key":"ref2","first-page":"138","article-title":"Bone mineral density in patients with psoriatic arthritis","volume":"28","author":"B Frediani","year":"2001","journal-title":"J Rheumatol"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1002\/path.2153","article-title":"Lymphocytes and synovial fluid fibroblasts support osteoclastogenesis through RANKL, TNFalpha, and IL-7 in an in vitro model derived from human psoriatic arthritis","volume":"212","author":"S Colucci","year":"2007","journal-title":"J Pathol"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1038\/nature01658","article-title":"Osteoclast differentiation and activation","volume":"423","author":"WJ Boyle","year":"2003","journal-title":"Nature"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1172\/JCI200316069","article-title":"Mechanisms of TNF-alpha- and RANKL-mediated osteoclastogenesis and bone resorption in psoriatic arthritis","volume":"111","author":"CT Ritchlin","year":"2003","journal-title":"J Clin Invest"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1136\/ard.2007.076091","article-title":"The effect of etanercept on osteoclast precursor frequency and enhancing bone marrow oedema in patients with psoriatic arthritis","volume":"67","author":"AP Anandarajah","year":"2008","journal-title":"Ann Rheum Dis"},{"key":"ref7","first-page":"451","article-title":"Prevalence of Atherosclerotic Risk Factors and the Metabolic Syndrome in Patients with Chronic Inflammatory Arthritis","volume":"303","author":"CM Chi","year":"2011","journal-title":"Arch Dermatol Res"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1136\/annrheumdis-2011-200123","article-title":"Comparison of rheumatoid articular adipose and synovial tissue reactivity to proinflammatory stimuli: contribution to adipocytokine network","volume":"71","author":"E Kontny","year":"2012","journal-title":"Ann Rheum Dis"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1136\/bjo.2007.128769","article-title":"Leptin increases in Vogt-Koyanagi-Harada (VKH) disease and promotes cell proliferation and inflammatory cytokine secretion","volume":"92","author":"L Liu","year":"2008","journal-title":"Br J Ophthalmol"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"2665","DOI":"10.1002\/art.21972","article-title":"Classification criteria for psoriatic arthritis: development of new criteria from a large international study","volume":"54","author":"W Taylor","year":"2006","journal-title":"Arthritis Rheum"},{"key":"ref11","first-page":"526","article-title":"Response criteria for psoriatic arthritis II: Developing and comparing response criteria for PsA","volume":"67","author":"DD Gladman","year":"2008","journal-title":"Ann Rheum Dis"},{"key":"ref12","first-page":"2571","article-title":"Evaluation of response using the Psoriatic Arthritis Joint Activity Index scoring tool in patients treated with adalimumab: Post-hoc analysis of the ACCLAIM study","volume":"36","author":"DD Gladman","year":"2009","journal-title":"J Rheumatol"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"2698","DOI":"10.1002\/art.22805","article-title":"Infliximab inhibits progression of radiographic damage in patients with active psoriatic arthritis through one year of treatment: results from the induction and maintenance psoriatic arthritis clinical trial 2","volume":"56","author":"D van der Heijde","year":"2007","journal-title":"Arthritis Rheum"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"2263","DOI":"10.1002\/1529-0131(199812)41:12<2263::AID-ART23>3.0.CO;2-I","article-title":"The bath ankylosing spondylitis radiology index (BASRI): a new, validated approach to disease assessment","volume":"41","author":"K Mackay","year":"1998","journal-title":"Arthritis Rheum"},{"key":"ref15","first-page":"988","article-title":"A new dimension to outcome: application of the bath ankylosing spondylitis radiology index","volume":"26","author":"A Calin","year":"1999","journal-title":"J Rheumatol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"1854","DOI":"10.1002\/art.23488","article-title":"Enhanced osteoclastogenesis in patients with tophaceous gout: urate crystals promote osteoclast development through interactions with stromal cells","volume":"58","author":"N Dalbeth","year":"2008","journal-title":"Arthritis Rheum"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1007\/s10238-010-0117-2","article-title":"Osteoclastogenesis and arthritis","volume":"11","author":"N Maruotti","year":"2011","journal-title":"Clin Exp Med"},{"key":"ref18","first-page":"1349","article-title":"Highly increased levels of tumor necrosis factor-alpha and other proinflammatory cytokines in psoriatic arthritis synovial fluid","volume":"6","author":"G Partsch","year":"1997","journal-title":"J Rheumatol"},{"key":"ref19","first-page":"1544","article-title":"Patterns of cytokine production in psoriatic synovium","volume":"25","author":"C Ritchlin","year":"1998","journal-title":"J Rheumatol"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1097\/01.bor.0000129718.13939.81<","article-title":"Pathogenesis of psoriatic arthritis","volume":"16","author":"AP Anandarajah","year":"2004","journal-title":"Curr Opin Rheumatol"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"1150","DOI":"10.1136\/ard.2004.032268","article-title":"Infliximab improves signs and symptoms of psoriatic arthritis: results of the IMPACT 2 trial","volume":"64","author":"C Antoni","year":"2005","journal-title":"Ann Rheum Dis"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"2264","DOI":"10.1002\/art.20335","article-title":"Etanercept treatment of psoriatic arthritis, safety, efficacy, and effect on disease progression","volume":"50","author":"PJ Mease","year":"2004","journal-title":"Arthritis Rheum"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"3279","DOI":"10.1002\/art.21306","article-title":"Adalimumab Effectiveness in Psoriatic Arthritis Trial Study Group. Adalimumab for the treatment of patients with moderately to severely active psoriatic arthritis: results of a double-blind, randomized, placebo-controlled trial","volume":"52","author":"PJ Mease","year":"2005","journal-title":"Arthritis Rheum"},{"key":"ref24","first-page":"851","article-title":"Psoriasis Work Group. Guidelines of care for the management of psoriasis and psoriatic arthritis: Section 2. Psoriatic arthritis: overview and guideline of care for treatment with an emphasis on the biologics","volume":"58","author":"A Gottlieb","year":"2008","journal-title":"J Am Acad Dermatol"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1002\/art.30291","article-title":"Adipocytokines as driving forces in rheumatic diseases","volume":"63","author":"E Neumann","year":"2011","journal-title":"Arthritis Rheum"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1136\/ard.62.10.913","article-title":"A role for leptin in rheumatic diseases?","volume":"62","author":"G Palmer","year":"2003","journal-title":"Ann Rheum Dis"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1111\/j.1365-2133.2008.08742.x","article-title":"Serum leptin levels, skin leptin and leptin receptor expression in psoriasis","volume":"159","author":"AA Cerman","year":"2008","journal-title":"Br J Dermatol"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1136\/ard.2005.046540","article-title":"Changes in plasma levels of fat-derived hormones adiponectin, leptin, resistin and visfatin in patients with rheumatoid arthritis","volume":"65","author":"M Otero","year":"2006","journal-title":"Annals of the rheumatic diseases"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"3118","DOI":"10.1002\/art.11303","article-title":"Evidence for a key role of leptin in osteoarthritis","volume":"48","author":"H Dumond","year":"2003","journal-title":"Arthritis and Rheumatism"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1007\/s00403-011-1159-3","article-title":"Kinetics of circulating Th17 cytokines and adipokines in psoriasis patients","volume":"303","author":"N Hideki","year":"2011","journal-title":"Arch Dermatol Res"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1084\/jem.20030382","article-title":"Specific recruitment of antigen-presenting cells by chemerin, a novel processed ligand from human inflammatory fluids","volume":"198","author":"V Wittamer","year":"2003","journal-title":"J Exp Med"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"34661","DOI":"10.1074\/jbc.M504868200","article-title":"Chemerin activation by serine proteases of the coagulation, fibrinolytic and inflammatory cascades","volume":"280","author":"BA Zabel","year":"2005","journal-title":"J Biol Chem"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"4687","DOI":"10.1210\/en.2007-0175","article-title":"Chemerin is a novel adipokine associated with obesity and metabolic syndrome","volume":"148","author":"K Bozaoglu","year":"2007","journal-title":"Endocrinology"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"6489","DOI":"10.4049\/jimmunol.0901037","article-title":"Mouse ChemR23 is expressed in dendritic cell subsets and macrophages, and mediates an anti-inflammatory activity of chemerin in a lung disease model","volume":"183","author":"S Luangsay","year":"2009","journal-title":"J Immunol"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"1762","DOI":"10.1016\/j.bbrc.2009.12.150","article-title":"Identification of chemerin receptor (ChemR23) in human endothelial cells: chemerin-induced endothelial angiogenesis","volume":"391","author":"J Kaur","year":"2010","journal-title":"Biochem Biophys Res Commun"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"R228","DOI":"10.1186\/ar3215","article-title":"Human articular chondrocytes express ChemR23 and chemerin; ChemR23 promotes inflammatory signalling upon binding the ligand chemerin(21\u2013157)","volume":"12","author":"V Berg","year":"2010","journal-title":"Arthritis Res Ther"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1136\/ard.2010.132399","article-title":"Expanding the adipokine network in cartilage: identification and regulation of novel factors in human and murine chondrocytes","volume":"70","author":"J Conde","year":"2011","journal-title":"Ann Rheum Dis"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1084\/jem.20041310","article-title":"Role of ChemR23 in directing the migration of myeloid and plasmacytoid dendritic cells to lymphoid organs and inflamed skin","volume":"201","author":"W Vermi","year":"2005","journal-title":"J Exp Med"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1359\/jbmr.091106","article-title":"Role of chemerin\/CMKLR1 signaling in adipogenesis and osteoblastogenesis of bone marrow stem cells","volume":"25","author":"S Muruganandan","year":"2010","journal-title":"J Bone Miner Res"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.fsi.2006.04.003","article-title":"Gene transcript changes in individual rainbow trout livers following an inflammatory stimulus","volume":"22","author":"L Gerwick","year":"2007","journal-title":"Fish and Shellfish Immunol"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.2337\/db06-1506","article-title":"Omentin plasma levels and gene expression are decreased in obesity","volume":"56","author":"CM Souza Batista","year":"2007","journal-title":"Diabetes"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.bbaexp.2005.11.005","article-title":"Genomic structure of human omentin, a new adipocytokine expressed in omental adipose tissue","volume":"1732","author":"A Schaffler","year":"2005","journal-title":"Biochim Biophys Acta"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"1410","DOI":"10.1136\/ard.2009.119735","article-title":"Vaspin and omentin: new adipokines differentially regulated at the site of inflammation in rheumatoid arthritis","volume":"69","author":"\u0160 Ladislav","year":"2010","journal-title":"Ann Rheum Dis"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"5789","DOI":"10.4049\/jimmunol.174.9.5789","article-title":"Resistin, an adipokine with potent proinflammatory properties","volume":"174","author":"M Bokarewa","year":"2005","journal-title":"J immunol"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1530\/eje.1.02057","article-title":"Effects of retinoid therapy on insulin sensitivity, lipid profile and circulating adipocytokines","volume":"154","author":"S Corbetta","year":"2006","journal-title":"Eur J Endocrinol"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1093\/rheumatology\/ken187","article-title":"Resistin in serum is associated with higher levels of IL-1Ra in post-menopausal women with rheumatoid arthritis","volume":"47","author":"H Forsblad d'Elia","year":"2008","journal-title":"Rheumatology (Oxford)"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1136\/ard.2006.054734","article-title":"Resistin in rheumatoid arthritis synovial tissue, synovial fluid and serum","volume":"66","author":"L Senolt","year":"2007","journal-title":"Ann Rheum Dis"},{"key":"ref48","first-page":"311","article-title":"Anti-TNF-alpha therapy modulates resistin in patients with rheumatoid arthritis","volume":"26","author":"MA Gonzalez-Gay","year":"2008","journal-title":"Clin Exp Rheumatol"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/j.joca.2008.08.007","article-title":"Resistin is elevated following traumatic joint injury and causes matrix degradation and release of inflammatory cytokines from articular cartilage in vitro","volume":"17","author":"JH Lee","year":"2009","journal-title":"Osteoarthritis Cartilage"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"1993","DOI":"10.1002\/art.27473","article-title":"Resistin induces expression of proinflammatory cytokines and chemokines in human articular chondrocytes via transcription and messenger RNA stabilization","volume":"62","author":"Z Zhang","year":"2010","journal-title":"Arthritis Rheum"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0046740","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,30]],"date-time":"2024-04-30T21:34:21Z","timestamp":1714512861000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0046740"}},"subtitle":[],"editor":[{"given":"Brenda","family":"Smith","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2012,10,29]]},"references-count":50,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2012,10,29]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0046740","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,10,29]]}}}