{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,4]],"date-time":"2022-04-04T07:51:51Z","timestamp":1649058711534},"reference-count":36,"publisher":"Public Library of Science (PLoS)","issue":"11","license":[{"start":{"date-parts":[[2012,11,8]],"date-time":"2012-11-08T00:00:00Z","timestamp":1352332800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0047119","type":"journal-article","created":{"date-parts":[[2012,11,8]],"date-time":"2012-11-08T17:53:50Z","timestamp":1352397230000},"page":"e47119","update-policy":"http:\/\/dx.doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":3,"title":["Screening for and Verification of Novel Mutations Associated with Drug Resistance in the HIV Type 1subtype B\u2032 in China"],"prefix":"10.1371","volume":"7","author":[{"given":"Hanping","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qingmao","family":"Geng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Guo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daomin","family":"Zhuang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lin","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yongjian","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zuoyi","family":"Bao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siyang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingyun","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2012,11,8]]},"reference":[{"key":"ref1","first-page":"156","article-title":"2011 Update of the Drug Resistance Mutations in HIV-1","volume":"19","author":"VA Johnson","year":"2011","journal-title":"Top Antivir Med"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1159\/000331998","article-title":"The HIVdb system for HIV-1 genotypic resistance interpretation","volume":"55","author":"MW Tang","year":"2012","journal-title":"Intervirology"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1186\/1742-4690-8-89","article-title":"HIV-1 predisposed to acquiring resistance to maraviroc (MVC) and other CCR5 antagonists in vitro has an inherent, low-level ability to utilize MVC-bound CCR5 for entry","volume":"8","author":"M Roche","year":"2011","journal-title":"Retrovirology"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"1476","DOI":"10.3390\/v2071476","article-title":"The \u201cConnection\u201d Between HIV Drug Resistance and RNase H","volume":"2","author":"KA Delviks-Frankenberry","year":"2010","journal-title":"Viruses"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"1973","DOI":"10.1128\/AAC.00870-09","article-title":"Combinations of Mutations in the Connection Domain of Human Immunodeficiency Virus Type 1 Reverse Transcriptase: Assessing the Impact on Nucleoside and Nonnucleoside Reverse Transcriptase Inhibitor Resistance","volume":"54","author":"S Gupta","year":"2010","journal-title":"Antimicrob Agents Chemother"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1073\/pnas.0609642104","article-title":"Mutations in the connection domain of HIV-1 reverse transcriptase increase 3\u2032-azido-3\u2032-deoxythymidine resistance","volume":"104","author":"GN Nikolenko","year":"2007","journal-title":"Proc Nat Acad Sci U S A"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"26966","DOI":"10.1074\/jbc.M110.105775","article-title":"N348I in HIV-1 reverse transcriptase can counteract the nevirapine-mediated bias toward RNase H cleavage during plus-strand initiation","volume":"285","author":"MJ Biondi","year":"2010","journal-title":"J Biol Chem"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"38700","DOI":"10.1074\/jbc.M110.153783","article-title":"The N348I mutation at the connection subdomain of HIV-1 reverse transcriptase decreases binding to nevirapine","volume":"285","author":"MM Schuckmann","year":"2010","journal-title":"J Biol Chem"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"4799","DOI":"10.1128\/AAC.00716-10","article-title":"Mechanisms involved in the selection of HIV-1 reverse transcriptase thumb subdomain polymorphisms associated with nucleoside analogue therapy failure","volume":"54","author":"G Betancor","year":"2010","journal-title":"Antimicrob Agents Chemother"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.antiviral.2009.02.189","article-title":"Clinical relevance of substitutions in the connection subdomain and RNase H domain of HIV-1 reverse transcriptase from a cohort of antiretroviral treatment-naive patients","volume":"82","author":"A Hachiya","year":"2009","journal-title":"Antiviral Res"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"2093","DOI":"10.1073\/pnas.0409823102","article-title":"Mechanism for nucleoside analog-mediated abrogation of HIV-1 replication: balance between RNase H activity and nucleotide excision","volume":"102","author":"GN Nikolenko","year":"2005","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1093\/jac\/dkg079","article-title":"Impact of clade diversity on HIV-1 virulence, antiretroviral drug sensitivity and drug resistance","volume":"51","author":"S Spira","year":"2003","journal-title":"J Antimicrob Chemother"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1097\/QAD.0b013e32832ba8ec","article-title":"Antiretroviral medication adherence and the development of class-specific antiretroviral resistance","volume":"23","author":"EM Gardner","year":"2009","journal-title":"AIDS"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1089\/aid.2010.0092","article-title":"Naturally Occurring Polymorphisms and Primary Drug Resistance Profile Among Antiretroviral-Naive Individuals in Bangalore, India","volume":"26","author":"U Neogi","year":"2010","journal-title":"AIDS Res Hum Retroviruses"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1186\/1742-4690-8-69","article-title":"Subunit-specific mutational analysis of residue N348 in HIV-1 reverse transcriptase","volume":"8","author":"J Radzio","year":"2011","journal-title":"Retrovirology"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1086\/590945","article-title":"The effect of highly active antiretroviral therapy on mortality among HIV-infected former plasma donors in China","volume":"47","author":"F Zhang","year":"2008","journal-title":"Clin Infect Dis"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"1851","DOI":"10.1097\/QAD.0b013e32830f4c62","article-title":"The epidemic origin and molecular properties of B\u2032: a founder strain of the HIV-1 transmission in Asia","volume":"22","author":"X Deng","year":"2008","journal-title":"AIDS"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1089\/aid.1995.11.1081","article-title":"Rapid molecular epidemiology of human immunodeficiency virus transmission","volume":"11","author":"EL Delwart","year":"1995","journal-title":"AIDS Res Hum Retroviruses"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1097\/00002030-199508000-00004","article-title":"The evolving molecular epidemiology of HIV-1 envelope subtypes in injecting drug users in Bangkok, Thailand: implications for HIV vaccine trials","volume":"9","author":"ML Kalish","year":"1995","journal-title":"AIDS"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"1573","DOI":"10.1089\/aid.1994.10.1573","article-title":"Early HIV type 1 strains in Thailand were not responsible for the current epidemic","volume":"10","author":"ML Kalish","year":"1994","journal-title":"AIDS Res Hum Retroviruses"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1097\/QAD.0b013e328351430d","article-title":"Tracing the origin and history of HIV-1 subtype B\u2032 epidemic by near full-length genome analyses","volume":"26","author":"Z Li","year":"2012","journal-title":"AIDS"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"11367","DOI":"10.1128\/JVI.74.23.11367-11376.2000","article-title":"Characterization of a virtually full-length human immunodeficiency virus type 1 genome of a prevalent intersubtype (C\/B\u2032) recombinant strain in China","volume":"l74","author":"L Su","year":"2000","journal-title":"J Viro"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"11286","DOI":"10.1128\/JVI.74.23.11286-11295.2000","article-title":"A recent outbreak of human immunodeficiency virus type 1 infection in southern China was initiated by two highly homogeneous, geographically separated strains, circulating recombinant form AE and a novel BC recombinant","volume":"74","author":"S Piyasirisilp","year":"2000","journal-title":"J Virol"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"e335","DOI":"10.1371\/journal.pmed.0040335","article-title":"N348I in the connection domain of HIV-1 reverse transcriptase confers zidovudine and nevirapine resistance","volume":"4","author":"SH Yap","year":"2007","journal-title":"PloS Med"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"2157","DOI":"10.1128\/JCM.39.6.2157-2165.2001","article-title":"Human Immunodeficiency Virus type 1 drug resistance testing: a comparison of three sequence-based methods. Human Immunodeficiency Virus type 1 drug resistance testing: a comparison of three sequence-based methods","volume":"39","author":"M Erali","year":"2001","journal-title":"J Clin Microbiol"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1002\/jmv.20788","article-title":"Relationship between mutations in HIV-1 RNase H domain and nucleoside reverse transcriptase inhibitors resistance mutations in na\u00efve and pre-treated HIV infected patients","volume":"79","author":"B Roquebert","year":"2007","journal-title":"J Med Virol"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1097\/QAD.0b013e3280129964","article-title":"Identification of accessory mutations associated with high-level resistance in HIV-1 reverse transcriptase","volume":"21","author":"PA Cane","year":"2007","journal-title":"AIDS"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1093\/jac\/dkp200","article-title":"HIV-1 reverse transcriptase thumb subdomain polymorphisms associated with virological failure to nucleoside drug combinations","volume":"64","author":"G Betancor","year":"2009","journal-title":"J Antimicrob Chemother"},{"key":"ref29","first-page":"75","article-title":"Genotypic resistance tests for the management of the HIV-infected patient with non-B viral isolates","volume":"Suppl 106","author":"U Visco-Comandini","year":"2003","journal-title":"Scand J Infect Dis"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1186\/1742-4690-7-80","article-title":"Comparative biochemical analysis of recombinant reverse transcriptase enzymes of HIV-1 subtype B and subtype C","volume":"7","author":"HT Xu","year":"2010","journal-title":"Retrovirology"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"4812","DOI":"10.1128\/AAC.00829-10","article-title":"Distinct mutation pathways of non-subtype B HIV-1 during in vitro resistance selection with nonnucleoside reverse transcriptase inhibitors","volume":"54","author":"MT Lai","year":"2010","journal-title":"Antimicrob Agents Chemother"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"985","DOI":"10.3851\/IMP1658","article-title":"HIV type-1 drug resistance in antiretroviral treatment-naive adults infected with non-B subtype virus in the United Kingdom","volume":"15","author":"DN Chilton","year":"2010","journal-title":"Antivir Ther"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1089\/aid.2010.0260","article-title":"Resistance-associated mutation prevalence according to subtypes B and non-B of HIV type 1 in antiretroviral-experienced patients in Minas Gerais, Brazil","volume":"27","author":"MR Westin","year":"2011","journal-title":"AIDS Res Hum Retroviruses"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/1758-2652-12-11","article-title":"Differences in resistance mutations among HIV-1 non-subtype B infections: a systematic review of evidence (1996\u20132008)","volume":"12","author":"JL Martinez-Cajas","year":"2009","journal-title":"J Int AIDS Soc"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/j.jcv.2011.09.005","article-title":"Primary HIV-1 drug resistance in the C-terminal domains of viral reverse transcriptase among drug-naive patients from Southern Brazil","volume":"52","author":"AF Santos","year":"2011","journal-title":"J Clin Virol"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1016\/j.micinf.2010.08.003","article-title":"Impact of CRF01 AE-specific polymorphic mutations G335D and A371V in the connection subdomain of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) on susceptibility to nucleoside RT inhibitors","volume":"12","author":"J Tanuma","year":"2010","journal-title":"Microbes Infect"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0047119","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,10,24]],"date-time":"2018-10-24T03:37:10Z","timestamp":1540352230000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0047119"}},"subtitle":[],"editor":[{"given":"K. T.","family":"Jeang","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2012,11,8]]},"references-count":36,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2012,11,8]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0047119","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,11,8]]}}}