{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T20:34:40Z","timestamp":1723062880341},"reference-count":54,"publisher":"Public Library of Science (PLoS)","issue":"11","license":[{"start":{"date-parts":[[2012,11,6]],"date-time":"2012-11-06T00:00:00Z","timestamp":1352160000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/publicdomain\/zero\/1.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0047835","type":"journal-article","created":{"date-parts":[[2012,11,6]],"date-time":"2012-11-06T22:10:39Z","timestamp":1352239839000},"page":"e47835","update-policy":"http:\/\/dx.doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":15,"title":["Mannose-Binding Lectin Regulates Host Resistance and Pathology during Experimental Infection with Trypanosoma cruzi"],"prefix":"10.1371","volume":"7","author":[{"given":"Antonio Gigliotti","family":"Rothfuchs","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ester","family":"Roff\u00ea","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda","family":"Gibson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allen W.","family":"Cheever","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. Alan B.","family":"Ezekowitz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazue","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario","family":"Steindel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alan","family":"Sher","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andr\u00e9","family":"B\u00e1fica","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2012,11,6]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1146\/annurev.immunol.21.120601.140954","article-title":"Collectins and ficolins: humoral lectins of the innate immune defense","volume":"21","author":"U Holmskov","year":"2003","journal-title":"Annu Rev Immunol"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1016\/S0140-6736(89)91849-7","article-title":"Association of low levels of mannan-binding protein with a common defect of opsonisation","volume":"2","author":"M Super","year":"1989","journal-title":"Lancet"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.molimm.2005.06.018","article-title":"Clinical manifestations of mannan-binding lectin deficiency","volume":"43","author":"S Thiel","year":"2006","journal-title":"Mol Immunol"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"S335","DOI":"10.1086\/374746","article-title":"Role of the mannose-binding lectin in innate immunity","volume":"187","author":"RA Ezekowitz","year":"2003","journal-title":"J Infect Dis"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1084\/jem.20032207","article-title":"Mannose-binding lectin-deficient mice are susceptible to infection with <italic>Staphylococcus aureus<\/italic>","volume":"199","author":"L Shi","year":"2004","journal-title":"J Exp Med"},{"key":"ref6","first-page":"305","article-title":"Mannose-binding lectin: structure, function, genetics and disease associations","volume":"2","author":"MW Turner","year":"2000","journal-title":"Rev Immunogenet"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"2610","DOI":"10.4049\/jimmunol.164.5.2610","article-title":"Purification and characterization of two mannan-binding lectins from mouse serum","volume":"164","author":"S Hansen","year":"2000","journal-title":"J Immunol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"8188","DOI":"10.1128\/IAI.73.12.8188-8193.2005","article-title":"Relative roles of complement factor 3 and mannose-binding lectin in host defense against infection","volume":"73","author":"K Takahashi","year":"2005","journal-title":"Infect Immun"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1111\/j.1365-2249.2004.02616.x","article-title":"Mannan-binding lectin modulates the response to HSV-2 infection","volume":"138","author":"M Gadjeva","year":"2004","journal-title":"Clin Exp Immunol"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"3934","DOI":"10.1016\/j.molimm.2008.06.021","article-title":"Increased susceptibility of complement factor B\/C2 double knockout mice and mannan-binding lectin knockout mice to systemic infection with <italic>Candida albicans<\/italic>","volume":"45","author":"K Held","year":"2008","journal-title":"Mol Immunol"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1084\/jem.20071164","article-title":"Mannose-binding lectin enhances Toll-like receptors 2 and 6 signaling from the phagosome","volume":"205","author":"WK Ip","year":"2008","journal-title":"J Exp Med"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"1769","DOI":"10.4049\/jimmunol.176.3.1769","article-title":"Deficiency of mannose-binding lectin greatly increases susceptibility to postburn infection with <italic>Pseudomonas aeruginosa<\/italic>","volume":"176","author":"M Moller-Kristensen","year":"2006","journal-title":"J Immunol"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1016\/S1286-4579(02)01597-6","article-title":"Lack of mannose-binding lectin-A enhances survival in a mouse model of acute septic peritonitis","volume":"4","author":"K Takahashi","year":"2002","journal-title":"Microbes Infect"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1111\/j.1365-3083.2005.01591.x","article-title":"Mannan-binding lectin recognizes structures on ischaemic reperfused mouse kidneys and is implicated in tissue injury","volume":"61","author":"M Moller-Kristensen","year":"2005","journal-title":"Scand J Immunol"},{"key":"ref15","unstructured":"WHO (2002) The world health report."},{"key":"ref16","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1016\/j.coi.2007.06.003","article-title":"Immune system recognition of <italic>Trypanosoma cruzi<\/italic>","volume":"19","author":"RL Tarleton","year":"2007","journal-title":"Curr Opin Immunol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"1711","DOI":"10.4049\/jimmunol.172.3.1711","article-title":"Impaired production of proinflammatory cytokines and host resistance to acute infection with <italic>Trypanosoma cruzi<\/italic> in mice lacking functional myeloid differentiation factor 88","volume":"172","author":"MA Campos","year":"2004","journal-title":"J Immunol"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"3515","DOI":"10.4049\/jimmunol.177.6.3515","article-title":"Cutting edge: TLR9 and TLR2 signaling together account for MyD88-dependent control of parasitemia in <italic>Trypanosoma cruzi<\/italic> infection","volume":"177","author":"A Bafica","year":"2006","journal-title":"J Immunol"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/S0169-4758(98)01295-2","article-title":"Natural human immunity to trypanosomes","volume":"14","author":"S Tomlinson","year":"1998","journal-title":"Parasitol Today"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"3042","DOI":"10.4049\/jimmunol.172.5.3042","article-title":"The classical activation pathway of the human complement system is specifically inhibited by calreticulin from <italic>Trypanosoma cruzi<\/italic>","volume":"172","author":"V Ferreira","year":"2004","journal-title":"J Immunol"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1016\/j.molimm.2009.08.030","article-title":"Role of early lectin pathway activation in the complement-mediated killing of <italic>Trypanosoma cruzi<\/italic>","volume":"47","author":"S Cestari Idos","year":"2009","journal-title":"Mol Immunol"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.clim.2011.03.008","article-title":"MASP2 haplotypes are associated with high risk of cardiomyopathy in chronic Chagas disease","volume":"140","author":"AB Boldt","year":"2011","journal-title":"Clin Immunol"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"229","DOI":"10.4269\/ajtmh.2012.11-0539","article-title":"Mannose-binding lectin and Toll-like receptor polymorphisms and Chagas disease in Chile","volume":"86","author":"T Weitzel","year":"2012","journal-title":"Am J Trop Med Hyg"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"692","DOI":"10.4049\/jimmunol.147.2.692","article-title":"Molecular characterization of the mouse mannose-binding proteins. The mannose-binding protein A but not C is an acute phase reactant","volume":"147","author":"K Sastry","year":"1991","journal-title":"J Immunol"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1046\/j.1365-3083.2001.00908.x","article-title":"Characterization and quantification of mouse mannan-binding lectins (MBL-A and MBL-C) and study of acute phase responses","volume":"53","author":"H Liu","year":"2001","journal-title":"Scand J Immunol"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"475","DOI":"10.2307\/3279787","article-title":"Tissue tropism of different <italic>Trypanosoma cruzi<\/italic> strains","volume":"64","author":"RC Melo","year":"1978","journal-title":"J Parasitol"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"272","DOI":"10.4269\/ajtmh.1964.13.272","article-title":"Chronic and Progressive Myocarditis and Myositis in C3h Mice Infected with <italic>Trypanosoma cruzi<\/italic>","volume":"13","author":"EE Federici","year":"1964","journal-title":"Am J Trop Med Hyg"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"e44","DOI":"10.2741\/926","article-title":"Clinical management of chronic Chagas cardiomyopathy","volume":"8","author":"MO Rocha","year":"2003","journal-title":"Front Biosci"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"6945","DOI":"10.4049\/jimmunol.169.12.6945","article-title":"L-MBP is expressed in epithelial cells of mouse small intestine","volume":"169","author":"K Uemura","year":"2002","journal-title":"J Immunol"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"1462","DOI":"10.4049\/jimmunol.170.3.1462","article-title":"Differential expression of the murine mannose-binding lectins A and C in lymphoid and nonlymphoid organs and tissues","volume":"170","author":"S Wagner","year":"2003","journal-title":"J Immunol"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"507874","DOI":"10.1155\/2012\/507874","article-title":"The Immune Response to <italic>Trypanosoma cruzi<\/italic>: Role of Toll-Like Receptors and Perspectives for Vaccine Development","volume":"2012","author":"MM Rodrigues","year":"2012","journal-title":"J Parasitol Res"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"e185","DOI":"10.1371\/journal.ppat.0030185","article-title":"Bradykinin B2 Receptors of dendritic cells, acting as sensors of kinins proteolytically released by <italic>Trypanosoma cruzi<\/italic>, are critical for the development of protective type-1 responses","volume":"3","author":"AC Monteiro","year":"2007","journal-title":"PLoS Pathog"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/S1471-4922(02)02283-3","article-title":"Chemokines, inflammation and <italic>Trypanosoma cruzi<\/italic> infection","volume":"18","author":"MM Teixeira","year":"2002","journal-title":"Trends Parasitol"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"2345","DOI":"10.1161\/01.ATV.0000240517.69201.77","article-title":"Serum levels of mannose-binding lectin and the risk of future coronary artery disease in apparently healthy men and women","volume":"26","author":"TT Keller","year":"2006","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"2188","DOI":"10.1161\/CIRCULATIONAHA.108.830661","article-title":"Macrophage-specific expression of mannose-binding lectin controls atherosclerosis in low-density lipoprotein receptor-deficient mice","volume":"119","author":"RA Matthijsen","year":"2009","journal-title":"Circulation"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1111\/j.1365-2249.2007.03324.x","article-title":"Mannan-binding lectin is a determinant of survival in infective endocarditis","volume":"148","author":"CT Tran","year":"2007","journal-title":"Clin Exp Immunol"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"3656","DOI":"10.1128\/IAI.61.9.3656-3663.1993","article-title":"A partial cDNA clone of trypomastigote decay-accelerating factor (T-DAF), a developmentally regulated complement inhibitor of <italic>Trypanosoma cruzi<\/italic>, has genetic and functional similarities to the human complement inhibitor DAF","volume":"61","author":"DV Tambourgi","year":"1993","journal-title":"Infect Immun"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"1276","DOI":"10.1086\/592167","article-title":"Complement C2 receptor inhibitor trispanning confers an increased ability to resist complement-mediated lysis in <italic>Trypanosoma cruzi<\/italic>","volume":"198","author":"S Cestari Idos","year":"2008","journal-title":"J Infect Dis"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1159\/000228160","article-title":"Ficolins: complement-activating lectins involved in innate immunity","volume":"2","author":"M Matsushita","year":"2010","journal-title":"J Innate Immun"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"2649","DOI":"10.1128\/IAI.64.7.2649-2656.1996","article-title":"The major surface glycoprotein of <italic>Trypanosoma cruzi<\/italic> amastigotes are ligands of the human serum mannose-binding protein","volume":"64","author":"SJ Kahn","year":"1996","journal-title":"Infect Immun"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/0166-6851(94)90158-9","article-title":"Recognition of the major cell surface glycoconjugates of Leishmania parasites by the human serum mannan-binding protein","volume":"66","author":"PJ Green","year":"1994","journal-title":"Mol Biochem Parasitol"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"1402","DOI":"10.1084\/jem.143.6.1402","article-title":"<italic>Trypanosoma cruzi<\/italic>: mechanism of entry and intracellular fate in mammalian cells","volume":"143","author":"N Nogueira","year":"1976","journal-title":"J Exp Med"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1017\/S0031182000054536","article-title":"<italic>Trypanosoma cruzi<\/italic>: continuous cultivation with murine cell lines","volume":"2)","author":"L Hudson","year":"1984","journal-title":"Parasitology 88 (Pt"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1084\/jem.168.2.649","article-title":"Amastigotes of <italic>Trypanosoma cruzi<\/italic> sustain an infective cycle in mammalian cells","volume":"168","author":"V Ley","year":"1988","journal-title":"J Exp Med"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1590\/S0074-02761999000700005","article-title":"A role for extracellular amastigotes in the immunopathology of Chagas disease","volume":"94","author":"J Scharfstein","year":"1999","journal-title":"Mem Inst Oswaldo Cruz"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"7523","DOI":"10.1073\/pnas.1101748108","article-title":"Targeting of mannan-binding lectin-associated serine protease-2 confers protection from myocardial and gastrointestinal ischemia\/reperfusion injury","volume":"108","author":"WJ Schwaeble","year":"2012","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"1212","DOI":"10.1086\/512683","article-title":"Genotypes of the mannan-binding lectin gene and susceptibility to visceral leishmaniasis and clinical complications","volume":"195","author":"DP Alonso","year":"2007","journal-title":"J Infect Dis"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"e34113","DOI":"10.1371\/journal.pone.0034113","article-title":"Genetic evidence of functional ficolin-2 haplotype as susceptibility factor in cutaneous leishmaniasis","volume":"7","author":"A Assaf","year":"2012","journal-title":"PLoS One"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/S1074-7613(00)80596-8","article-title":"Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function","volume":"9","author":"O Adachi","year":"1998","journal-title":"Immunity"},{"key":"ref50","first-page":"238","article-title":"[Clinical analysis based on subsidiary tests of a patient from which was isolated, 23 years ago, the Y strain of <italic>Trypanosoma cruzi<\/italic>]","volume":"16","author":"V Amato Neto","year":"1974","journal-title":"Rev Inst Med Trop Sao Paulo"},{"key":"ref51","first-page":"389","article-title":"Therapeutic activity and criterion of cure on mice experimentally infected with <italic>Trypanosoma cruzi<\/italic>","volume":"4","author":"Z Brener","year":"1962","journal-title":"Rev Inst Med Trop Sao Paulo"},{"key":"ref52","doi-asserted-by":"crossref","first-page":"4045","DOI":"10.4049\/jimmunol.157.9.4045","article-title":"In the absence of endogenous IFN-\u03b3, mice develop unimpaired IL-12 responses to <italic>Toxoplasma gondii<\/italic> while failing to control acute infection","volume":"157","author":"TM Scharton-Kersten","year":"1996","journal-title":"J Immunol"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/S0166-6851(03)00093-8","article-title":"Rapid quantitation of <italic>Trypanosoma cruzi<\/italic> in host tissue by real-time PCR","volume":"129","author":"KL Cummings","year":"2003","journal-title":"Mol Biochem Parasitol"},{"key":"ref54","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1021\/ac60289a036","article-title":"New spectrophotometric method for the determination of proline in tissue hydrolyzates","volume":"42","author":"I Bergman","year":"1970","journal-title":"Anal Chem"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0047835","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,26]],"date-time":"2023-06-26T16:02:41Z","timestamp":1687795361000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0047835"}},"subtitle":[],"editor":[{"given":"Partha","family":"Mukhopadhyay","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2012,11,6]]},"references-count":54,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2012,11,6]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0047835","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,11,6]]}}}