{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T22:09:16Z","timestamp":1784153356566,"version":"3.55.0"},"reference-count":42,"publisher":"Public Library of Science (PLoS)","issue":"11","license":[{"start":{"date-parts":[[2012,11,29]],"date-time":"2012-11-29T00:00:00Z","timestamp":1354147200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0049560","type":"journal-article","created":{"date-parts":[[2012,11,29]],"date-time":"2012-11-29T23:05:32Z","timestamp":1354230332000},"page":"e49560","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":59,"title":["Metabolic and Functional Connectivity Changes in Mal de Debarquement Syndrome"],"prefix":"10.1371","volume":"7","author":[{"given":"Yoon-Hee","family":"Cha","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shruthi","family":"Chakrapani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexis","family":"Craig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert W.","family":"Baloh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2012,11,29]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1016\/S0140-6736(02)38129-7","article-title":"The Pathology of Sea-sickness","volume":"118","author":"JA Irwin","year":"1881","journal-title":"The Lancet"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1111\/j.1749-6632.1996.tb15734.x","article-title":"Mild mal de debarquement after sailing","volume":"781","author":"H Cohen","year":"1996","journal-title":"Ann N Y Acad Sci"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/0957-4271(95)00005-Z","article-title":"Clinical features of mal de debarquement: adaptation and habituation to sea conditions","volume":"5","author":"CR Gordon","year":"1995","journal-title":"J Vestib Res"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1007\/s00415-008-0837-3","article-title":"Clinical features and associated syndromes of mal de debarquement","volume":"255","author":"YH Cha","year":"2008","journal-title":"J Neurol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/S0196-0709(87)80007-8","article-title":"Persistent mal de debarquement syndrome: a motion-induced subjective disorder of balance","volume":"8","author":"JJ Brown","year":"1987","journal-title":"Am J Otolaryngol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1001\/archotol.125.6.615","article-title":"Mal de debarquement","volume":"125","author":"TC Hain","year":"1999","journal-title":"Archives of Otolaryngology- Head and Neck Surgery"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1055\/s-0029-1241038","article-title":"Mal de debarquement","volume":"29","author":"YH Cha","year":"2009","journal-title":"Semin Neurol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1007\/s00415-006-0440-4","article-title":"Mal de debarquement: Pseudo-hallucinations from vestibular memory?","volume":"254","author":"L Moeller","year":"2007","journal-title":"J Neurol"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/0028-3932(71)90067-4","article-title":"The assessment and analysis of handedness: the Edinburgh inventory","volume":"9","author":"RC Oldfield","year":"1971","journal-title":"Neuropsychologia"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1111\/j.1600-0447.1983.tb09716.x","article-title":"The hospital anxiety and depression scale","volume":"67","author":"AS Zigmond","year":"1983","journal-title":"Acta Psychiatr Scand"},{"key":"ref11","first-page":"13","article-title":"DPARSF: A MATLAB Toolbox for \u201cPipeline\u201d Data Analysis of Resting-State fMRI","volume":"4","author":"Y Chao-Gan","year":"2010","journal-title":"Front Syst Neurosci"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1016\/j.neuroimage.2004.12.034","article-title":"A new SPM toolbox for combining probabilistic cytoarchitectonic maps and functional imaging data","volume":"25","author":"SB Eickhoff","year":"2005","journal-title":"Neuroimage"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1126\/science.175.4029.1471","article-title":"Cortical afferents to the entorhinal cortex of the rhesus monkey","volume":"175","author":"GW Van Hoesen","year":"1972","journal-title":"Science"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1093\/brain\/93.4.793","article-title":"An anatomical study of converging sensory pathways within the cerebral cortex of the monkey","volume":"93","author":"EG Jones","year":"1970","journal-title":"Brain"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1016\/j.pnpbp.2009.03.038","article-title":"Entorhinal cortex and cognition","volume":"33","author":"E Coutureau","year":"2009","journal-title":"Progress in Neuro-Psychopharmacology and Biological Psychiatry"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1038\/nature03721","article-title":"Microstructure of a spatial map in the entorhinal cortex","volume":"436","author":"T Hafting","year":"2005","journal-title":"Nature"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1038\/nn1905","article-title":"Experience-dependent rescaling of entorhinal grids","volume":"10","author":"C Barry","year":"2007","journal-title":"Nat Neurosci"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1038\/nature05601","article-title":"Hippocampal remapping and grid realignment in entorhinal cortex","volume":"446","author":"M Fyhn","year":"2007","journal-title":"Nature"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1038\/nature08704","article-title":"Evidence for grid cells in a human memory network","volume":"463","author":"CF Doeller","year":"2010","journal-title":"Nature"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"14466","DOI":"10.1073\/pnas.1004243107","article-title":"Lateralized human hippocampal activity predicts navigation based on sequence or place memory","volume":"107","author":"K Igl\u00f3i","year":"2010","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1126\/science.1201652","article-title":"Reduction of theta rhythm dissociates grid cell spatial periodicity from directional tuning","volume":"332","author":"MP Brandon","year":"2011","journal-title":"Science"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1002\/hipo.20512","article-title":"Grid cell mechanisms and function: contributions of entorhinal persistent spiking and phase resetting","volume":"18","author":"ME Hasselmo","year":"2008","journal-title":"Hippocampus"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"11128","DOI":"10.1523\/JNEUROSCI.1327-10.2010","article-title":"Intrinsic circuit organization and theta-gamma oscillation dynamics in the entorhinal cortex of the rat","volume":"30","author":"P Quilichini","year":"2010","journal-title":"J Neurosci"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1056\/NEJMoa1107212","article-title":"Memory enhancement and deep-brain stimulation of the entorhinal area","volume":"366","author":"N Suthana","year":"2012","journal-title":"N Engl J Med"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1002\/cne.902510403","article-title":"Connections of the parahippocampal cortex in the cat. II. Subcortical afferents","volume":"251","author":"P Room","year":"1986","journal-title":"J Comp Neurol"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1093\/cercor\/bhn114","article-title":"Entorhinal cortex inhibits medial prefrontal cortex and modulates the activity states of electrophysiologically characterized pyramidal neurons in vivo","volume":"19","author":"O Valenti","year":"2009","journal-title":"Cereb Cortex"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1016\/j.neuron.2006.10.023","article-title":"Integration and segregation of activity in entorhinal-hippocampal subregions by neocortical slow oscillations","volume":"52","author":"Y Isomura","year":"2006","journal-title":"Neuron"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1126\/science.272.5265.1176","article-title":"Entorhinal-hippocampal interactions revealed by real-time imaging","volume":"272","author":"T Iijima","year":"1996","journal-title":"Science"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1038\/nature01171","article-title":"Graded persistent activity in entorhinal cortex neurons","volume":"420","author":"AV Egorov","year":"2002","journal-title":"Nature"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"2176","DOI":"10.1152\/jn.01033.2002","article-title":"Amygdala input promotes spread of excitatory neural activity from perirhinal cortex to the entorhinal-hippocampal circuit","volume":"89","author":"R Kajiwara","year":"2003","journal-title":"J Neurophysiol"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/S1364-6613(02)01924-1","article-title":"Amygdala oscillations and the consolidation of emotional memories","volume":"6","author":"D Par\u00e9","year":"2002","journal-title":"Trends Cogn Sci"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"8800","DOI":"10.1523\/JNEUROSCI.23-25-08800.2003","article-title":"Stimulation of medial prefrontal cortex decreases the responsiveness of central amygdala output neurons","volume":"23","author":"GJ Quirk","year":"2003","journal-title":"J Neurosci"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0022-3999(01)00296-3","article-title":"The validity of the Hospital Anxiety and Depression Scale: an updated literature review","volume":"52","author":"I Bjelland","year":"2002","journal-title":"Journal of psychosomatic research"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1038\/386824a0","article-title":"Subgenual prefrontal cortex abnormalities in mood disorders","volume":"386","author":"WC Drevets","year":"1997","journal-title":"Nature"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1097\/00001756-199703030-00048","article-title":"Cingulate function in depression: a potential predictor of treatment response","volume":"8","author":"HS Mayberg","year":"1997","journal-title":"Neuroreport"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.biopsych.2010.09.034","article-title":"The subcallosal cingulate gyrus in the context of major depression","volume":"69","author":"C Hamani","year":"2011","journal-title":"Biol Psychiatry"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S1364-6613(98)01265-0","article-title":"The functional neuroanatomy of emotion and affective style","volume":"3","author":"RJ Davidson","year":"1999","journal-title":"Trends Cogn Sci"},{"key":"ref38","first-page":"4","article-title":"The application of positron emission tomography to the study of normal and pathologic emotions","volume":"58","author":"EM Reiman","year":"1997","journal-title":"Journal of Clinical Psychiatry"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1196\/annals.1410.004","article-title":"Serotonergic systems, anxiety, and affective disorder: focus on the dorsomedial part of the dorsal raphe nucleus","volume":"1148","author":"CA Lowry","year":"2008","journal-title":"Ann N Y Acad Sci"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/s13311-010-0006-0","article-title":"Neuroimaging in psychiatric disorders","volume":"8","author":"JC Masdeu","year":"2011","journal-title":"Neurotherapeutics"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1097\/YCO.0b013e328319bd10","article-title":"Current status of brain imaging in anxiety disorders","volume":"22","author":"C Damsa","year":"2009","journal-title":"Current opinion in psychiatry"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/S0091-3057(01)00687-6","article-title":"Glucose metabolism in the amygdala in depression: relationship to diagnostic subtype and plasma cortisol levels","volume":"71","author":"WC Drevets","year":"2002","journal-title":"Pharmacol Biochem Behav"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0049560","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,6]],"date-time":"2019-07-06T07:43:53Z","timestamp":1562399033000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0049560"}},"subtitle":[],"editor":[{"given":"Matthew","family":"Thurtell","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2012,11,29]]},"references-count":42,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2012,11,29]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0049560","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,11,29]]}}}