{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T13:27:33Z","timestamp":1759411653904},"reference-count":44,"publisher":"Public Library of Science (PLoS)","issue":"11","license":[{"start":{"date-parts":[[2012,11,28]],"date-time":"2012-11-28T00:00:00Z","timestamp":1354060800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0050337","type":"journal-article","created":{"date-parts":[[2012,11,28]],"date-time":"2012-11-28T21:54:32Z","timestamp":1354139672000},"page":"e50337","update-policy":"http:\/\/dx.doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":15,"title":["The Impact of Influenza Vaccinations on the Adverse Effects and Hospitalization Rate in the Elderly: A National Based Study in an Asian Country"],"prefix":"10.1371","volume":"7","author":[{"given":"Tsung-Yu","family":"Ho","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kuang-Yung","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tza-Ta","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yung-Sung","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hsu-Chueh","family":"Ho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pesus","family":"Chou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chun-Hung","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chang-Kao","family":"Wei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei-Chang","family":"Lian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ting-Chang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hsien-Bin","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ching-Chih","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2012,11,28]]},"reference":[{"key":"ref1","first-page":"1","article-title":"Prevention and control of influenza. Recommendations of the Advisory Committee on Immunization Practices (ACIP)","volume":"59","year":"2010","journal-title":"MMWR Recomm Rep"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1001\/jama.289.2.179","article-title":"Mortality associated with influenza and respiratory syncytial virus in the united states","volume":"289","author":"WW Thompson","year":"2003","journal-title":"JAMA: The Journal of the American Medical Association"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1001\/jama.292.11.1333","article-title":"Influenza-associated hospitalizations in the united states","volume":"292","author":"WW Thompson","year":"2004","journal-title":"JAMA: The Journal of the American Medical Association"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"1604","DOI":"10.1086\/425323","article-title":"Reducing Major Cause-Specific Hospitalization Rates and Shortening Hospital Stays after Influenza Vaccination","volume":"39","author":"CS Wang","year":"2004","journal-title":"Clinical Infectious Diseases"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1056\/NEJMoa070844","article-title":"Effectiveness of Influenza Vaccine in the Community-Dwelling Elderly","volume":"357","author":"KL Nichol","year":"2007","journal-title":"New England Journal of Medicine"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.clineuro.2003.11.002","article-title":"Guillain\u2013Barr\u00e9 syndrome coexisting with pericarditis or nephrotic syndrome after influenza vaccination","volume":"106","author":"CD Kao","year":"2004","journal-title":"Clinical Neurology and Neurosurgery"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"2839","DOI":"10.1016\/j.vaccine.2006.10.006","article-title":"Bell&apos;s palsy associated with influenza vaccination: Two case reports","volume":"25","author":"CH Chou","year":"2007","journal-title":"Vaccine"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1056\/NEJMoa030595","article-title":"Use of the Inactivated Intranasal Influenza Vaccine and the Risk of Bell&apos;s Palsy in Switzerland","volume":"350","author":"M Mutsch","year":"2004","journal-title":"New England Journal of Medicine"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1093\/oxfordjournals.aje.a112795","article-title":"Guillain-Barre syndrome following vaccination in the National Influenza Immunization Program, United States, 1976\u20131977","volume":"110","author":"LB Schonberger","year":"1979","journal-title":"Am J Epidemiol"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"6284","DOI":"10.1016\/j.vaccine.2009.01.040","article-title":"Single dose vaccination with AS03-adjuvanted H5N1 vaccines in a randomized trial induces strong and broad immune responsiveness to booster vaccination in adults","volume":"27","author":"TF Schwarz","year":"2009","journal-title":"Vaccine"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.biopha.2004.04.009","article-title":"Autoimmunity induced by adjuvant hydrocarbon oil components of vaccine","volume":"58","author":"Y Kuroda","year":"2004","journal-title":"Biomedicine & Pharmacotherapy"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0896-8411(03)00083-0","article-title":"Induction of lupus autoantibodies by adjuvants","volume":"21","author":"M Satoh","year":"2003","journal-title":"Journal of Autoimmunity"},{"key":"ref13","doi-asserted-by":"crossref","unstructured":"Bardage C, Persson I, \u00d6rtqvist \u00c5, Bergman U, Ludvigsson JF, <etal>et al<\/etal>.. (2011) Neurological and autoimmune disorders after vaccination against pandemic influenza A (H1N1) with a monovalent adjuvanted vaccine: population based cohort study in Stockholm, Sweden. BMJ 343.","DOI":"10.1136\/bmj.d5956"},{"key":"ref14","unstructured":"US Deparment of Health and Human Services (2000) Healthy people 2010. With understanding and improving health and objectives-full report, with commentary. Washington, DC."},{"key":"ref15","unstructured":"NHIRD (2009) Available: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.nhri.org.tw\/nhird\/\/date_01.html\" xlink:type=\"simple\">http\/\/www.nhri.org.tw\/nhird\/\/date_01.html<\/ext-link>.Accessed 2009 Jan 2."},{"key":"ref16","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1161\/STROKEAHA.109.567735","article-title":"Tuberculosis and the Risk of Ischemic Stroke","volume":"41","author":"JJ Sheu","year":"2010","journal-title":"Stroke"},{"key":"ref17","unstructured":"European Medicines Agency (2009) CHMP recommendations for the pharmacovigilance plan as part of the risk management plan to be submitted with the marketing authorisation application for a pandemic influenza vaccine. Report No EMEA\/359381\/2009 rev EMA, 2009."},{"key":"ref18","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1111\/j.1524-4733.2006.00158.x","article-title":"The relationship between influenza vaccination and outpatient visits for upper respiratory infection by the elderly in Taiwan","volume":"10","author":"YW Tsai","year":"2007","journal-title":"Value Health"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.schres.2011.02.018","article-title":"The incidence and relative risk factors for developing cancer among patients with schizophrenia: A nine-year follow-up study","volume":"129","author":"FHC Chou","year":"2011","journal-title":"Schizophrenia research"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1161\/STROKEAHA.110.597070","article-title":"Risk of Stroke in Patients Hospitalized for Isolated Vertigo","volume":"42","author":"CC Lee","year":"2011","journal-title":"Stroke"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"e40590","DOI":"10.1371\/journal.pone.0040590","article-title":"Multivariate Analyses to Assess the Effects of Surgeon and Hospital Volume on Cancer Survival Rates: A Nationwide Population-Based Study in Taiwan","volume":"7","author":"CM Chang","year":"2012","journal-title":"PLoS ONE"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"757","DOI":"10.7326\/0003-4819-127-8_Part_2-199710151-00064","article-title":"Estimating causal effects from large data sets using propensity scores","volume":"127","author":"DB Rubin","year":"1997","journal-title":"Ann Intern Med"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1186\/1471-2458-9-275","article-title":"Threat-responsiveness and the decision to obtain free influenza vaccinations among the older adults in Taiwan","volume":"9","author":"YC Li","year":"2009","journal-title":"BMC Public Health"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"YS103","DOI":"10.1097\/00005650-199305001-00017","article-title":"Tasks in statistical inference for studying variation in medicine","volume":"31","author":"DB Rubin","year":"1993","journal-title":"Med Care"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"2265","DOI":"10.1002\/(SICI)1097-0258(19981015)17:19<2265::AID-SIM918>3.0.CO;2-B","article-title":"Propensity score methods for bias reduction in the comparison of a treatment to a non-randomized control group","volume":"17","author":"RB D'Agostino Jr","year":"1998","journal-title":"Stat Med"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1093\/oxfordjournals.aje.a115974","article-title":"Guillain-Barre syndrome and influenza vaccination in the US Army, 1980\u20131988","volume":"133","author":"JD Roscelli","year":"1991","journal-title":"Am J Epidemiol"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1001\/jama.1982.03330060038030","article-title":"Guillain-Barre syndrome in the United States, 1979\u20131980 and 1980\u20131981. Lack of an association with influenza vaccination","volume":"248","author":"JE Kaplan","year":"1982","journal-title":"JAMA"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1056\/NEJM198106253042601","article-title":"Guillain-Barre syndrome and the 1978\u20131979 influenza vaccine","volume":"304","author":"ES Hurwitz","year":"1981","journal-title":"N Engl J Med"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1093\/aje\/kws196","article-title":"Guillain-Barr\u00e9 Syndrome During the 2009\u20132010 H1N1 Influenza Vaccination Campaign: Population-based Surveillance Among 45 Million Americans","volume":"175","author":"ME Wise","year":"2012","journal-title":"American Journal of Epidemiology"},{"key":"ref30","first-page":"657","article-title":"Preliminary results: surveillance for Guillain-Barr\u00e9 syndrome after receipt of influenza A (H1N1) 2009 monovalent vaccine \u2013 United States, 2009\u20132010","volume":"59","year":"2010","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1002\/ana.410300418","article-title":"The use of hospital discharge data for public health surveillance of Guillain-Barr\u00e9 syndrome","volume":"30","author":"BG Koobatian TJ","year":"1991","journal-title":"Ann Neurol"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1136\/jnnp.63.4.494","article-title":"Guillain-Barr\u00e9 syndrome in Taiwan: a clinical study of 167 patients","volume":"63","author":"RK Lyu","year":"1997","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"ref33","first-page":"225","article-title":"The good, the bad and the ugly: vaccination","volume":"2","author":"SY Aharon-Maor A","year":"2000","journal-title":"Isr Med Assoc J"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1006\/jaut.1999.0346","article-title":"Vaccination and autoimmunity-\u2018vaccinosis\u2019: a dangerous liaison?","volume":"14","author":"A-MA Shoenfeld Y","year":"2000","journal-title":"J Autoimmun"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1136\/ard.52.12.843","article-title":"Can immunisation trigger rheumatoid arthritis?","volume":"52","author":"DP Symmons","year":"1993","journal-title":"Annals of the Rheumatic Diseases"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1016\/j.vaccine.2009.10.017","article-title":"Priming with AS03A-adjuvanted H5N1 influenza vaccine improves the kinetics, magnitude and durability of the immune response after a heterologous booster vaccination: An open non-randomised extension of a double-blind randomised primary study","volume":"28","author":"I Leroux-Roels","year":"2010","journal-title":"Vaccine"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"1473","DOI":"10.1001\/jama.1996.03540180029029","article-title":"Persons With Chronic Conditions","volume":"276","author":"C Hoffman","year":"1996","journal-title":"JAMA: The Journal of the American Medical Association"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"e117","DOI":"10.1161\/STROKEAHA.109.571299","article-title":"Infectious Burden and Carotid Plaque Thickness","volume":"41","author":"MSV Elkind","year":"2010","journal-title":"Stroke"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"2611","DOI":"10.1056\/NEJMoa041747","article-title":"Risk of Myocardial Infarction and Stroke after Acute Infection or Vaccination","volume":"351","author":"L Smeeth","year":"2004","journal-title":"New England Journal of Medicine"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1001\/archinte.158.6.645","article-title":"A Study of the Impact of Influenza on the Functional Status of Frail Older People","volume":"158","author":"WH Barker","year":"1998","journal-title":"Arch Intern Med"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1111\/j.1524-4733.2006.00158.x","article-title":"The Relationship between Influenza Vaccination and Outpatient Visits for Upper Respiratory Infection by the Elderly in Taiwan","volume":"10","author":"YW Tsai","year":"2007","journal-title":"Value in Health"},{"key":"ref42","first-page":"CD005188","article-title":"Interventions to increase influenza vaccination rates of those 60 years and older in the community","volume":"(9)","author":"RM Thomas RE","year":"2010","journal-title":"Cochrane Database Syst Rev 2010"},{"key":"ref43","unstructured":"North Carolina Center for Public Health Preparedness (2010) The Public Health Wrokforce Assessement Report, North Carolina, 2004. Available: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/nccphp.sph.unc.edu\/wfds_assess_rpts\/Statewide.pdf\" xlink:type=\"simple\">http:\/\/nccphp.sph.unc.edu\/wfds_assess_rpts\/Statewide.pdf<\/ext-link>. Accessed 2010 May 10."},{"key":"ref44","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1086\/655136","article-title":"Increased Risk of Guillain-Barr\u00e9 Syndrome following Recent Herpes Zoster: A Population-Based Study across Taiwan","volume":"51","author":"JH Kang","year":"2010","journal-title":"Clinical Infectious Diseases"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0050337","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,6]],"date-time":"2019-07-06T05:22:15Z","timestamp":1562390535000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0050337"}},"subtitle":[],"editor":[{"given":"Jianqing","family":"Xu","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2012,11,28]]},"references-count":44,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2012,11,28]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0050337","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,11,28]]}}}