{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T18:45:14Z","timestamp":1792003514852,"version":"4.4.0"},"reference-count":66,"publisher":"Public Library of Science (PLoS)","issue":"1","license":[{"start":{"date-parts":[[2013,1,4]],"date-time":"2013-01-04T00:00:00Z","timestamp":1357257600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0053234","type":"journal-article","created":{"date-parts":[[2013,1,4]],"date-time":"2013-01-04T17:10:28Z","timestamp":1357319428000},"page":"e53234","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":53,"title":["Association between Common Variants near LBX1 and Adolescent Idiopathic Scoliosis Replicated in the Chinese Han Population"],"prefix":"10.1371","volume":"8","author":[{"given":"Wenjie","family":"Gao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Peng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guoyan","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anjing","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Ye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liangming","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Swarkar","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peiqiang","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongsheng","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2013,1,4]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1038\/ng.974","article-title":"A genome-wide association study identifies common variants near LBX1 associated with adolescent idiopathic scoliosis","volume":"43","author":"Y Takahashi","year":"2011","journal-title":"Nat Genet"},{"key":"ref2","first-page":"261","article-title":"Outline for the study of scoliosis","volume":"5","author":"J Cobb","year":"1948","journal-title":"American Academy of Orthopaedic Surgeons"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"2592","DOI":"10.1097\/00007632-199912150-00006","article-title":"Natural history","volume":"24","author":"SL Weinstein","year":"1999","journal-title":"Spine (Phila Pa 1976)"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1097\/BLO.0b013e3180d09dcc","article-title":"Genetic association of complex traits: using idiopathic scoliosis as an example","volume":"462","author":"JC Cheng","year":"2007","journal-title":"Clin Orthop Relat Res"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"2898","DOI":"10.1097\/BRS.0b013e3181891751","article-title":"The pathogenesis of adolescent idiopathic scoliosis: review of the literature","volume":"33","author":"JW Kouwenhoven","year":"2008","journal-title":"Spine (Phila Pa 1976)"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"2372","DOI":"10.1097\/00007632-200009150-00017","article-title":"Localization of susceptibility to familial idiopathic scoliosis","volume":"25","author":"CA Wise","year":"2000","journal-title":"Spine (Phila Pa 1976)"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"E94","DOI":"10.1097\/BRS.0b013e31818b88a5","article-title":"Genetic linkage localizes an adolescent idiopathic scoliosis and pectus excavatum gene to chromosome 18 q","volume":"34","author":"CA Gurnett","year":"2009","journal-title":"Spine (Phila Pa 1976)"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1086\/341607","article-title":"A genetic locus for adolescent idiopathic scoliosis linked to chromosome 19p13.3","volume":"71","author":"V Chan","year":"2002","journal-title":"Am J Hum Genet"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1007\/s00439-002-0785-4","article-title":"Assignment of a locus for autosomal dominant idiopathic scoliosis (IS) to human chromosome 17p11","volume":"111","author":"LB Salehi","year":"2002","journal-title":"Hum Genet"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"1815","DOI":"10.1097\/01.brs.0000227264.23603.dc","article-title":"Idiopathic scoliosis: identification of candidate regions on chromosome 19p13","volume":"31","author":"KJ Alden","year":"2006","journal-title":"Spine (Phila Pa 1976)"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1086\/513571","article-title":"CHD7 gene polymorphisms are associated with susceptibility to idiopathic scoliosis","volume":"80","author":"X Gao","year":"2007","journal-title":"Am J Hum Genet"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1136\/jmg.2007.051896","article-title":"Assignment of two loci for autosomal dominant adolescent idiopathic scoliosis to chromosomes 9q31.2-q34.2 and 17q25.3-qtel","volume":"45","author":"L Ocaka","year":"2008","journal-title":"J Med Genet"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"1366","DOI":"10.1002\/jor.20885","article-title":"A novel locus for adolescent idiopathic scoliosis on chromosome 12p","volume":"27","author":"CL Raggio","year":"2009","journal-title":"J Orthop Res"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1097\/01.BRS.0000049940.39801.E6","article-title":"Familial idiopathic scoliosis: evidence of an X-linked susceptibility locus","volume":"28","author":"CM Justice","year":"2003","journal-title":"Spine (Phila Pa 1976)"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1097\/01.brs.0000216603.91330.6f","article-title":"Association of estrogen receptor gene polymorphisms with susceptibility to adolescent idiopathic scoliosis","volume":"31","author":"J Wu","year":"2006","journal-title":"Spine (Phila Pa 1976)"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1097\/BRS.0b013e31818ad5ac","article-title":"Association of estrogen receptor beta gene polymorphisms with susceptibility to adolescent idiopathic scoliosis","volume":"34","author":"HQ Zhang","year":"2009","journal-title":"Spine (Phila Pa 1976)"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1038\/ejhg.2008.203","article-title":"Promoter polymorphism of matrilin-1 gene predisposes to adolescent idiopathic scoliosis in a Chinese population","volume":"17","author":"Z Chen","year":"2009","journal-title":"Eur J Hum Genet"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"1748","DOI":"10.1097\/BRS.0b013e3180b9f0ff","article-title":"Melatonin receptor 1B (MTNR1B) gene polymorphism is associated with the occurrence of adolescent idiopathic scoliosis","volume":"32","author":"XS Qiu","year":"2007","journal-title":"Spine (Phila Pa 1976)"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"2199","DOI":"10.1097\/BRS.0b013e31817c03f9","article-title":"Association study of tryptophan hydroxylase 1 and arylalkylamine N-acetyltransferase polymorphisms with adolescent idiopathic scoliosis in Han Chinese","volume":"33","author":"H Wang","year":"2008","journal-title":"Spine (Phila Pa 1976)"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"2700","DOI":"10.1097\/BRS.0b013e31815a5943","article-title":"Association between IL-6 and MMP-3 gene polymorphisms and adolescent idiopathic scoliosis: a case-control study","volume":"32","author":"L Aulisa","year":"2007","journal-title":"Spine (Phila Pa 1976)"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"2463","DOI":"10.1097\/01.brs.0000239179.81596.2b","article-title":"A relook into the association of the estrogen receptor [alpha] gene (PvuII, XbaI) and adolescent idiopathic scoliosis: a study of 540 Chinese cases","volume":"31","author":"NL Tang","year":"2006","journal-title":"Spine (Phila Pa 1976)"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1097\/BRS.0b013e3181e8755b","article-title":"Genetic variants in melatonin synthesis and signaling pathway are not associated with adolescent idiopathic scoliosis","volume":"36","author":"LM Nelson","year":"2011","journal-title":"Spine (Phila Pa 1976)"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1002\/jor.21322","article-title":"Replication study of the association between adolescent idiopathic scoliosis and two estrogen receptor genes","volume":"29","author":"Y Takahashi","year":"2011","journal-title":"J Orthop Res"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1002\/jor.21347","article-title":"Lack of association between adolescent idiopathic scoliosis and previously reported single nucleotide polymorphisms in MATN1, MTNR1B, TPH1, and IGF1 in a Japanese population","volume":"29","author":"Y Takahashi","year":"2011","journal-title":"J Orthop Res"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"1701","DOI":"10.1097\/BRS.0b013e3181c6ba13","article-title":"Lack of association between the promoter polymorphisms of MMP-3 and IL-6 genes and adolescent idiopathic scoliosis: a case-control study in a Chinese Han population","volume":"35","author":"Z Liu","year":"2010","journal-title":"Spine (Phila Pa 1976)"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"2357","DOI":"10.1097\/00007632-200211010-00009","article-title":"Association between estrogen receptor gene polymorphisms and curve severity of idiopathic scoliosis","volume":"27","author":"M Inoue","year":"2002","journal-title":"Spine (Phila Pa 1976)"},{"key":"ref27","first-page":"18","article-title":"Genetic association study of insulin-like growth factor-I (IGF-I) gene with curve severity and osteopenia in adolescent idiopathic scoliosis","volume":"123","author":"HY Yeung","year":"2006","journal-title":"Stud Health Technol Inform"},{"key":"ref28","doi-asserted-by":"crossref","unstructured":"Jiang J, Qian B, Mao S, Zhao Q, Qiu X, <etal>et al<\/etal>. (2011) A Promoter Polymorphism of Tissue Inhibitor of Metalloproteinase-2 (TIMP-2) Gene Is Associated With Severity of Thoracic Adolescent Idiopathic Scoliosis. Spine (Phila Pa 1976).","DOI":"10.1097\/BRS.0b013e31820e71e3"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1007\/s00264-011-1374-8","article-title":"Genomic polymorphisms of G-protein estrogen receptor 1 are associated with severity of adolescent idiopathic scoliosis","volume":"36","author":"Y Peng","year":"2012","journal-title":"Int Orthop"},{"key":"ref30","doi-asserted-by":"crossref","unstructured":"Qiu Y, Mao SH, Qian BP, Jiang J, Qiu XS, <etal>et al<\/etal>. (2011) A Promoter Polymorphism of Neurotrophin 3 (NTF3) Gene Is Associated With Curve Severity and Bracing Effectiveness in Adolescent Idiopathic Scoliosis. Spine (Phila Pa 1976).","DOI":"10.1097\/BRS.0b013e31823e5890"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1086\/423901","article-title":"The future of association studies: gene-based analysis and replication","volume":"75","author":"BM Neale","year":"2004","journal-title":"Am J Hum Genet"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1212\/WNL.63.6.955","article-title":"Association of genetic loci: Replication or not, that is the question","volume":"63","author":"J Ott","year":"2004","journal-title":"Neurology"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1038\/447655a","article-title":"Replicating genotype-phenotype associations","volume":"447","author":"SJ Chanock","year":"2007","journal-title":"Nature"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1038\/jhg.2012.11","article-title":"SNP rs11190870 near LBX1 is associated with adolescent idiopathic scoliosis in southern Chinese","volume":"57","author":"YH Fan","year":"2012","journal-title":"J Hum Genet"},{"key":"ref35","doi-asserted-by":"crossref","unstructured":"Jiang H, Qiu X, Dai J, Yan H, Zhu Z, <etal>et al<\/etal>. (2012) Association of rs11190870 near LBX1 with adolescent idiopathic scoliosis susceptibility in a Han Chinese population. Eur Spine J.","DOI":"10.1007\/s00586-012-2532-4"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"1456","DOI":"10.1093\/hmg\/ddq571","article-title":"Genome-wide association studies of adolescent idiopathic scoliosis suggest candidate susceptibility genes","volume":"20","author":"S Sharma","year":"2011","journal-title":"Hum Mol Genet"},{"key":"ref37","first-page":"111","article-title":"Adolescent idiopathic scoliosis: review and current concepts","volume":"64","author":"BV Reamy","year":"2001","journal-title":"Am Fam Physician"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1016\/S0140-6736(08)60658-3","article-title":"Adolescent idiopathic scoliosis","volume":"371","author":"SL Weinstein","year":"2008","journal-title":"Lancet"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/1748-7161-1-2","article-title":"Adolescent idiopathic scoliosis: natural history and long term treatment effects","volume":"1","author":"MA Asher","year":"2006","journal-title":"Scoliosis"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1007\/s002560050445","article-title":"Scoliosis circa 2000: radiologic imaging perspective. I. Diagnosis and pretreatment evaluation","volume":"27","author":"AE Oestreich","year":"1998","journal-title":"Skeletal Radiol"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"2318","DOI":"10.1097\/00007632-199911150-00006","article-title":"Ten-year follow-up evaluation of a school screening program for scoliosis. Is the forward-bending test an accurate diagnostic criterion for the screening of scoliosis","volume":"24","author":"T Karachalios","year":"1999","journal-title":"Spine (Phila Pa 1976)"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.2106\/00004623-199408000-00011","article-title":"The Milwaukee brace for the treatment of adolescent idiopathic scoliosis. A review of one thousand and twenty patients","volume":"76","author":"JE Lonstein","year":"1994","journal-title":"J Bone Joint Surg Am"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"1823","DOI":"10.1148\/rg.307105061","article-title":"Scoliosis imaging: what radiologists should know","volume":"30","author":"H Kim","year":"2010","journal-title":"Radiographics"},{"key":"ref44","first-page":"667","article-title":"Scoliosis:its prognosis","volume":"18","author":"JC Risser","year":"1936","journal-title":"J Bone Joint Surg Am"},{"key":"ref45","first-page":"111","article-title":"The Iliac apophysis; an invaluable sign in the management of scoliosis","volume":"11","author":"JC Risser","year":"1958","journal-title":"Clin Orthop"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1073\/pnas.98.2.581","article-title":"High-throughput development and characterization of a genomewide collection of gene-based single nucleotide polymorphism markers by chip-based matrix-assisted laser desorption\/ionization time-of-flight mass spectrometry","volume":"98","author":"KH Buetow","year":"2001","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1093\/bioinformatics\/bth457","article-title":"Haploview: analysis and visualization of LD and haplotype maps","volume":"21","author":"JC Barrett","year":"2005","journal-title":"Bioinformatics"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1086\/519795","article-title":"PLINK: a tool set for whole-genome association and population-based linkage analyses","volume":"81","author":"S Purcell","year":"2007","journal-title":"Am J Hum Genet"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1302\/0301-620X.64B4.6284765","article-title":"Experimental scoliosis in primates: a neurological cause","volume":"64","author":"JR Pincott","year":"1982","journal-title":"J Bone Joint Surg Br"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1302\/0301-620X.66B1.6693473","article-title":"Scoliosis caused by section of dorsal spinal nerve roots","volume":"66","author":"JR Pincott","year":"1984","journal-title":"J Bone Joint Surg Br"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1097\/00007632-198706000-00003","article-title":"Scoliosis induced by medullary damage: an experimental study in rabbits","volume":"12","author":"C Barrios","year":"1987","journal-title":"Spine (Phila Pa 1976)"},{"key":"ref52","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1097\/00007632-198907000-00008","article-title":"Scoliosis induced by anterior and posterior rhizotomy","volume":"14","author":"SI Suk","year":"1989","journal-title":"Spine (Phila Pa 1976)"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1097\/00007632-199802010-00009","article-title":"Posterior tibial nerve somatosensory cortical evoked potentials in adolescent idiopathic scoliosis","volume":"23","author":"JC Cheng","year":"1998","journal-title":"Spine (Phila Pa 1976)"},{"key":"ref54","doi-asserted-by":"crossref","first-page":"1679","DOI":"10.1097\/00007632-199908150-00009","article-title":"Correlation between curve severity, somatosensory evoked potentials, and magnetic resonance imaging in adolescent idiopathic scoliosis","volume":"24","author":"JC Cheng","year":"1999","journal-title":"Spine (Phila Pa 1976)"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"E437","DOI":"10.1097\/01.brs.0000222048.47010.bf","article-title":"Balance control in adolescents with idiopathic scoliosis and disturbed somatosensory function","volume":"31","author":"X Guo","year":"2006","journal-title":"Spine (Phila Pa 1976)"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/0925-4773(95)00450-5","article-title":"Mouse Lbx1 and human LBX1 define a novel mammalian homeobox gene family related to the Drosophila lady bird genes","volume":"53","author":"K Jagla","year":"1995","journal-title":"Mech Dev"},{"key":"ref57","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/S0896-6273(02)00690-6","article-title":"Lbx1 specifies somatosensory association interneurons in the dorsal spinal cord","volume":"34","author":"MK Gross","year":"2002","journal-title":"Neuron"},{"key":"ref58","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1016\/S0896-6273(02)00689-X","article-title":"The homeodomain factor lbx1 distinguishes two major programs of neuronal differentiation in the dorsal spinal cord","volume":"34","author":"T Muller","year":"2002","journal-title":"Neuron"},{"key":"ref59","doi-asserted-by":"crossref","first-page":"1510","DOI":"10.1038\/nn1569","article-title":"Lbx1 and Tlx3 are opposing switches in determining GABAergic versus glutamatergic transmitter phenotypes","volume":"8","author":"L Cheng","year":"2005","journal-title":"Nat Neurosci"},{"key":"ref60","doi-asserted-by":"crossref","first-page":"4902","DOI":"10.1523\/JNEUROSCI.0717-07.2007","article-title":"Lbx1 acts as a selector gene in the fate determination of somatosensory and viscerosensory relay neurons in the hindbrain","volume":"27","author":"MA Sieber","year":"2007","journal-title":"J Neurosci"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1016\/j.ydbio.2008.06.031","article-title":"Ptf1a, Lbx1 and Pax2 coordinate glycinergic and peptidergic transmitter phenotypes in dorsal spinal inhibitory neurons","volume":"322","author":"M Huang","year":"2008","journal-title":"Dev Biol"},{"key":"ref62","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1016\/j.ajhg.2009.10.015","article-title":"Genomic dissection of population substructure of Han Chinese and its implication in association studies","volume":"85","author":"S Xu","year":"2009","journal-title":"Am J Hum Genet"},{"key":"ref63","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1038\/76211","article-title":"The 3\u2032 untranslated region of messenger RNA: A molecular &apos;hotspot&apos; for pathology","volume":"6","author":"B Conne","year":"2000","journal-title":"Nat Med"},{"key":"ref64","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1038\/oby.2009.303","article-title":"Variant in the 3\u2032 region of the IkappaBalpha gene associated with insulin resistance in Hispanic Americans: The IRAS Family Study","volume":"18","author":"MR Miller","year":"2010","journal-title":"Obesity (Silver Spring)"},{"key":"ref65","first-page":"2709","article-title":"Osteopenia: a new prognostic factor of curve progression in adolescent idiopathic scoliosis","volume":"87","author":"VW Hung","year":"2005","journal-title":"J Bone Joint Surg Am"},{"key":"ref66","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1007\/s00586-010-1649-6","article-title":"Timing of menarche in Chinese girls with and without adolescent idiopathic scoliosis: current results and review of the literature","volume":"20","author":"SH Mao","year":"2011","journal-title":"Eur Spine J"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0053234","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,7]],"date-time":"2019-07-07T20:02:52Z","timestamp":1562529772000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0053234"}},"subtitle":[],"editor":[{"given":"Nicholas John","family":"Timpson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2013,1,4]]},"references-count":66,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2013,1,4]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0053234","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,1,4]]}}}