{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T22:17:46Z","timestamp":1792275466321,"version":"4.4.0"},"reference-count":31,"publisher":"Public Library of Science (PLoS)","issue":"1","license":[{"start":{"date-parts":[[2013,1,14]],"date-time":"2013-01-14T00:00:00Z","timestamp":1358121600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0053579","type":"journal-article","created":{"date-parts":[[2013,1,14]],"date-time":"2013-01-14T23:47:22Z","timestamp":1358207242000},"page":"e53579","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":41,"title":["Pituitary Stalk Interruption Syndrome in Chinese People: Clinical Characteristic Analysis of 55 Cases"],"prefix":"10.1371","volume":"8","author":[{"given":"Qinghua","family":"Guo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiming","family":"Mu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jvming","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changyu","family":"Pan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingtao","family":"Dou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhaohui","family":"Lv","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianming","family":"Ba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baoan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoman","family":"Zou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lijuan","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinzhi","family":"Ouyang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guoqing","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xianling","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weijun","family":"Gu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nan","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Zang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bradley J.","family":"Erickson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2013,1,14]]},"reference":[{"key":"ref1","first-page":"487","article-title":"Transection of the pituitary stalk: development of an ectopic posterior lobe assessed with MR imaging","volume":"Radiology165","author":"I Fujisawa","year":"1987"},{"key":"ref2","first-page":"274","article-title":"Pituitary stalk transection syndrome","volume":"5","author":"C Barbeau","year":"1998","journal-title":"Arch Pediatr"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1007\/s11102-011-0337-9","article-title":"The pituitary stalk transection syndrome: multifaceted presentation in adulthood","volume":"15","author":"AG Ioachimescu","year":"2012","journal-title":"Pituitary"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"5430","DOI":"10.1210\/jc.2002-020672","article-title":"A 43-year-old male with untreated panhypopituitarism due to absence of the pituitary stalk: from dwarf to giant","volume":"87","author":"DT Den Ouden","year":"2002","journal-title":"J Clin Endocrinol Metab"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"472","DOI":"10.2169\/internalmedicine.37.472","article-title":"A hypopituitary patient who attained tall stature without growth hormone","volume":"37","author":"K Kageyama","year":"1998","journal-title":"Intern Med"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1159\/000324087","article-title":"Pituitary stalk dysgenesis-induced hypopituitarism in adult patients: prevalence, evolution of hormone dysfunction and genetic analysis","volume":"93","author":"E Fernandez-Rodriguez","year":"2011","journal-title":"Neuroendocrinology"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1530\/EJE-10-0892","article-title":"Pituitary stalk interruption syndrome in 83 patients: novel HESX1 mutation and severe hormonal prognosis in malformative forms","volume":"164","author":"R Reynaud","year":"2011","journal-title":"Eur J Endocrinol"},{"key":"ref8","first-page":"266","article-title":"Long-term evolution of endocrine disorders and effect of GH therapy in 35 patients with pituitary stalk interruption syndrome","volume":"64","author":"M Tauber","year":"2005","journal-title":"Horm Res"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"e16367","DOI":"10.1371\/journal.pone.0016367","article-title":"Pituitary stalk interruption syndrome: diagnostic delay and sensitivity of the auxological criteria of the growth hormone research society","volume":"6","author":"G Gascoin-Lachambre","year":"2011","journal-title":"PLoS One"},{"key":"ref10","first-page":"280","article-title":"A case of pituitary stalk interruption syndrome","volume":"21","author":"M Zhao","year":"2005","journal-title":"Chin J Endocrinol and Metab"},{"key":"ref11","first-page":"456","article-title":"A report of a case of pituitary stalk interruption syndrome","volume":"17","author":"Y Liu","year":"2004","journal-title":"Chinese Journal of Clinical Neurosciences"},{"key":"ref12","first-page":"480","article-title":"Analysis of 5 cases of pituitary stalk interruption syndrome and literature review","volume":"24","author":"QH Guo","year":"2008","journal-title":"Chin J Endocrinol and Metab"},{"key":"ref13","first-page":"3450","article-title":"Pituitary stalk interruption syndrome: a clinical-biological-genetic assessment of its pathogenesis","volume":"82","author":"G Pinto","year":"1997","journal-title":"J Clin Endocrinol Metab"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1210\/edrv.19.2.0329","article-title":"The diagnosis of growth hormone deficiency in children and adults","volume":"19","author":"SM Shalet","year":"1998","journal-title":"Endocr Rev"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1007\/s12098-007-0161-4","article-title":"Pituitary stalk interruption syndrome (PSIS)","volume":"74","author":"P Vijayanand","year":"2007","journal-title":"Indian J Pediatr"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.ejmg.2011.03.001","article-title":"17q21.31 microdeletion in a patient with pituitary stalk interruption syndrome","volume":"54","author":"S El Chehadeh-Djebbar","year":"2011","journal-title":"Eur J Med Genet"},{"key":"ref17","first-page":"16","article-title":"MRI characteristics and diagnosis of pituitary stalk interruption syndrome","volume":"2","author":"Fang XJ","year":"2007","journal-title":"Medicine World"},{"key":"ref18","first-page":"324","article-title":"MRI diagnosis of pituitary stalk interruption syndrome, Chin J of Radiology","volume":"40","author":"Y Liu","year":"2006"},{"key":"ref19","first-page":"305","article-title":"Clinical analysis of 13 cases of growth hormone deficiency with pituitary stalk interruption syndrome","volume":"48","author":"GL Wang","year":"2010","journal-title":"Chin J Pediatr"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"2408","DOI":"10.1210\/jcem.84.7.5849","article-title":"Growth hormone deficiency with ectopic neurohypophysis: anatomical variations and relationship between the visibility of the pituitary stalk asserted by magnetic resonance imaging and anterior pituitary function","volume":"84","author":"S Chen","year":"1999","journal-title":"J Clin Endocrinol Metab"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/S0022-3476(80)80680-9","article-title":"High incidence of perinatal insult in children with idiopathic hypopituitarism","volume":"96","author":"WH Craft","year":"1980","journal-title":"J Pediatr"},{"key":"ref22","doi-asserted-by":"crossref","unstructured":"Albertsson-Wikland K, Niklasson A, Karlberg P (1990) Birth data for patients who later develop growth hormone deficiency: preliminary analysis of a national register. Acta Paediatr Scand 370 (suppl): 115\u2013120.","DOI":"10.1111\/j.1651-2227.1990.tb11687.x"},{"key":"ref23","first-page":"1609","article-title":"MR imaging in idiopathic growth hormone deficiency","volume":"19","author":"J Hamilton","year":"1998","journal-title":"AJNR Am J Neuroradiol"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1530\/eje.0.1390084","article-title":"Relationships between neuroradiological and clinical features in apparently idiopathic hypopituitarism","volume":"139","author":"T Arrigo","year":"1998","journal-title":"Eur J Endocrinol"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"4649","DOI":"10.1210\/jcem.86.10.7962","article-title":"Growth and adult height in GH-treated children with nonacquired GH deficiency and idiopathic short stature: the influence of pituitary magnetic resonance imaging findings","volume":"86","author":"R Coutant","year":"2001","journal-title":"J Clin Endocrinol Metab"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1210\/jc.2004-1274","article-title":"Do all patients with childhood-onset growth hormone deficiency (GHD) and ectopic neurohypophysis have persistent GHD in adulthood?","volume":"90","author":"J Leger","year":"2005","journal-title":"J Clin Endocrinol Metab"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1111\/j.1365-2265.2007.03155.x","article-title":"Gonadotrophic status in adolescents with pituitary stalk interruption syndrome","volume":"69","author":"D Rottembourg","year":"2008","journal-title":"Clin Endocrinol (Oxf)"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/1472-6823-8-7","article-title":"Factors influencing the growth hormone peak and plasma insulin-like growth factor I in young adults with pituitary stalk interruption syndrome","volume":"11","author":"M Marcu","year":"2008","journal-title":"BMC Endocr Disord"},{"key":"ref29","first-page":"1495","article-title":"MR findings in growth hormone deficiency: correlation with severity of hypopituitarism","volume":"19","author":"L Kornreich","year":"1998","journal-title":"Am J Neuroradiol"},{"key":"ref30","unstructured":"Melmed S, Kleinberg D (2008) Anterior pituitary In: Kronenberg HM, et al. (eds) Williams Textbook of Endocrinology. 11th ed. Philadelphia, PA: USA. Saunders Elsevier 155\u2013243."},{"key":"ref31","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/S0720-048X(97)00086-7","article-title":"Imaging of the pituitary in children with growth disorders","volume":"26","author":"LJ Abernethy","year":"1998","journal-title":"Eur J Radiol"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0053579","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,10,20]],"date-time":"2018-10-20T05:07:14Z","timestamp":1540012034000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0053579"}},"subtitle":[],"editor":[{"given":"Raul M.","family":"Luque","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2013,1,14]]},"references-count":31,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2013,1,14]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0053579","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,1,14]]}}}