{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T12:03:40Z","timestamp":1775304220628,"version":"3.50.1"},"reference-count":38,"publisher":"Public Library of Science (PLoS)","issue":"2","license":[{"start":{"date-parts":[[2013,2,5]],"date-time":"2013-02-05T00:00:00Z","timestamp":1360022400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0055951","type":"journal-article","created":{"date-parts":[[2013,2,5]],"date-time":"2013-02-05T22:40:07Z","timestamp":1360104007000},"page":"e55951","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":33,"title":["A Genome-Wide Association Study to Detect QTL for Commercially Important Traits in Swiss Large White Boars"],"prefix":"10.1371","volume":"8","author":[{"given":"Doreen","family":"Becker","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Klaus","family":"Wimmers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henning","family":"Luther","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Hofer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tosso","family":"Leeb","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2013,2,5]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S0301-6226(98)00163-8","article-title":"Genetic parameters and trends of meat quality, carcass composition and performance traits in two selected lines of large white pigs","volume":"57","author":"AK Sonesson","year":"1998","journal-title":"Livest Prod Sci"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"324","DOI":"10.2527\/2005.832324x","article-title":"Genetic parameters for carcass composition and pork quality estimated in a commercial production chain","volume":"83","author":"HJ van Wijk","year":"2005","journal-title":"J Anim Sci"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/S0301-6226(00)00150-0","article-title":"Genetic Parameters for lean meat yield, meat quality, reproduction and feed efficiency traits for Australian pigs I. Description of traits and heritability estimates","volume":"65","author":"S Hermesch","year":"2000","journal-title":"Livest Prod Sci"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"1771","DOI":"10.1126\/science.8134840","article-title":"Genetic-mapping of quantitative trait loci for growth and fatness in pigs","volume":"263","author":"L Andersson","year":"1994","journal-title":"Science"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1111\/j.1365-2052.2005.01405.x","article-title":"Genome-wide identification of quantitative trait loci in a cross between Hampshire and Landrace I: carcass traits","volume":"37","author":"P Karlskov-Mortensen","year":"2006","journal-title":"Anim Genet"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/S0301-6226(01)00226-3","article-title":"Detection and characterization of quantitative trait loci for growth and reproduction traits in pigs","volume":"72","author":"DJ de Koning","year":"2001","journal-title":"Livest Prod Sci"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"2255","DOI":"10.2527\/1998.7692255x","article-title":"Identification of quantitative trait loci affecting carcass composition in swine: II. Muscling and wholesale product yield traits","volume":"76","author":"GA Rohrer","year":"1998","journal-title":"J Anim Sci"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"694","DOI":"10.2527\/1998.763694x","article-title":"Mapping Quantitative Trait Loci for carcass and meat quality traits in a Wild Boar\u00d7Large White intercross","volume":"76","author":"L Andersson-Eklund","year":"1998","journal-title":"J Anim Sci"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1046\/j.0931-2668.2003.00408.x","article-title":"Genome-wide linkage and QTL mapping in porcine F2 families generated from Pietrain, Meishan and Wild boar crosses","volume":"120","author":"H Geldermann","year":"2003","journal-title":"J Anim Breed Genet"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1093\/genetics\/149.2.1069","article-title":"Multiple marker mapping of quantitative trait loci in a cross between outbred wild boar and large white pigs","volume":"149","author":"SA Knott","year":"1998","journal-title":"Genetics"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1186\/1297-9686-34-3-371","article-title":"Results of a whole genome scan targeting QTL for growth and carcass traits in a Pietrain\u00d7Large White intercross","volume":"34","author":"C Nezer","year":"2002","journal-title":"Genet Sel Evol"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1007\/s003350020018","article-title":"A molecular genome scan analysis to identify chromosomal regions influencing economic traits in the pig. I. Growth and body composition","volume":"12","author":"M Malek","year":"2001","journal-title":"Mamm Genome"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1038\/nature02064","article-title":"A regulatory mutation in IGF2 causes a major QTL effect on muscle growth in the pig","volume":"425","author":"AS van Laere","year":"2003","journal-title":"Nature"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1126\/science.288.5469.1248","article-title":"A mutation in PRKAG3 associated with excess glycogen content in pig skeletal muscle","volume":"288","author":"D Milan","year":"2000","journal-title":"Science"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"2345","DOI":"10.1126\/science.1076641","article-title":"Finding genes that underlie complex traits","volume":"298","author":"AM Glazier","year":"2002","journal-title":"Science"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"e6524","DOI":"10.1371\/journal.pone.0006524","article-title":"Design of a High Density SNP Genotyping Assay in the Pig Using SNPs Identified and Characterized by Next Generation Sequencing Technology","volume":"4","author":"AM Ramos","year":"2009","journal-title":"PLoS ONE"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"e6501","DOI":"10.1371\/journal.pone.0006501","article-title":"Hippocampal Atrophy as a Quantitative Trait in a Genome-Wide Association Study Identifying Novel Susceptibility Genes for Alzheimer&apos;s Disease","volume":"4","author":"SG Potkin","year":"2009","journal-title":"PLoS ONE"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"3516","DOI":"10.1093\/hmg\/ddp296","article-title":"A genome-wide association study of northwestern Europeans involves the C-type natriuretic peptide signaling pathway in the etiology of human height variation","volume":"18","author":"K Estrada","year":"2009","journal-title":"Hum Mol Genet"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1126\/science.1137045","article-title":"A single IGF1 allele is a major determinant of small size in dogs","volume":"316","author":"NB Sutter","year":"2007","journal-title":"Science"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"2297","DOI":"10.2527\/jas.2010-3138","article-title":"A genome-wide association study of meat and carcass traits in Australian cattle","volume":"89","author":"S Bolormaa","year":"2011","journal-title":"J Anim Sci"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1111\/j.1365-2052.2011.02213.x","article-title":"A whole-genome association study for pig reproductive traits","volume":"43","author":"SK Onteru","year":"2011","journal-title":"Anim Genet"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1186\/1471-2156-11-42","article-title":"A genome-wide association study on androstenone levels in pigs reveals a cluster of candidate genes on chromosome 6","volume":"11","author":"N Duijvesteijn","year":"2010","journal-title":"BMC Genet"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1186\/1297-9686-43-42","article-title":"Whole-genome SNP association analysis of reproduction traits in the Finnish Landrace pig breed","volume":"43","author":"P Uimari","year":"2011","journal-title":"Genet Sel Evol"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1186\/1471-2164-13-22","article-title":"Genome-wide association scan and phased haplotype construction for quantitative trait loci affecting boar taint in three pig breeds","volume":"13","author":"VR Gregersen","year":"2012","journal-title":"BMC Genomics"},{"key":"ref25","doi-asserted-by":"crossref","unstructured":"Wang JY, Luo YR, Fu WX, Lu X, Zhou JP, et al.. (2012) Genome-wide association studies for hematological traits in swine. Anim Genet doi: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/dx.doi.org\/10.1111\/j.1365-2052.2012.02366.x\" xlink:type=\"simple\">10.1111\/j.1365-2052.2012.02366.x<\/ext-link>.","DOI":"10.1111\/j.1365-2052.2012.02366.x"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"3360","DOI":"10.2527\/jas.2011-4759","article-title":"Genome-wide association study of swine farrowing traits. Part II: Bayesian analysis of marker data","volume":"90","author":"JF Schneider","year":"2012","journal-title":"J Anim Sci"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1007\/s13353-012-0112-2","article-title":"Identification of chromosomal locations associated with tail biting and being a victim of tail-biting behaviour in the domestic pig (Sus scrofa domesticus)","volume":"53","author":"K Wilson","year":"2012","journal-title":"J Appl Genet"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1186\/1471-2164-13-583","article-title":"A genome wide association study for backfat thickness in Italian Large White pigs highlights new regions affecting fat deposition including neuronal genes","volume":"13","author":"L Fontanesi","year":"2012","journal-title":"BMC Genomics"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1046\/j.0931-2668.2003.00419.x","article-title":"Linkage and QTL mapping for Sus scrofa chromosome 2","volume":"120","author":"SS Lee","year":"2003","journal-title":"J Anim Breed Genet"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1093\/genetics\/164.2.621","article-title":"Identification of Quantitative Trait Loci for Production Traits in Commercial Pig Populations","volume":"164","author":"GJ Evans","year":"2003","journal-title":"Genetics"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"e14726","DOI":"10.1371\/journal.pone.0014726","article-title":"Genome-wide association study identifies loci for body composition and structural soundness traits in pigs","volume":"6","author":"B Fan","year":"2011","journal-title":"PLoS One"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1111\/j.1740-0929.2009.00713.x","article-title":"Quantitative trait loci for leg weakness traits in a Landrace purebred population","volume":"81","author":"Y Uemoto","year":"2010","journal-title":"Anim Sci J"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1017\/S1357729800053418","article-title":"Detection of quantitative trait loci for locomotion and osteochondrosis-related traits in Large White\u00d7Meishan pigs","volume":"76","author":"GJ Lee","year":"2003","journal-title":"Anim Sci"},{"key":"ref34","unstructured":"Homepage SUISAG (2012) Available: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.suisag.ch\/Zucht\/Leistungspr%C3%BCfungen\/Endproduktepr%C3%BCfung\/tabid\/109\/Default.aspx\" xlink:type=\"simple\">http:\/\/www.suisag.ch\/Zucht\/Leistungspr%C3%BCfungen\/Endproduktepr%C3%BCfung\/tabid\/109\/Default.aspx<\/ext-link>.Accessed 18 July 2012."},{"key":"ref35","doi-asserted-by":"crossref","first-page":"423","DOI":"10.2307\/2529430","article-title":"Best linear unbiased Estimation and Prediction under a selection model","volume":"31","author":"CR Henderson","year":"1975","journal-title":"Biometrics"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1093\/bioinformatics\/btm108","article-title":"GenABEL: an R library for genome-wide association analysis","volume":"23","author":"YS Aulchenko","year":"2007","journal-title":"Bioinformatics"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1038\/ng1847","article-title":"Principal component analysis corrects for stratification in genome-wide association studies","volume":"38","author":"AL Price","year":"2006","journal-title":"Nat Genet"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1038\/nature05911","article-title":"The Wellcome Trust Case Control Consortium (2007) Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls","volume":"447","journal-title":"Nature"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0055951","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,7]],"date-time":"2022-02-07T18:43:22Z","timestamp":1644259402000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0055951"}},"subtitle":[],"editor":[{"given":"Stephen","family":"Moore","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2013,2,5]]},"references-count":38,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2013,2,5]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0055951","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,2,5]]}}}