{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T10:22:55Z","timestamp":1790677375098,"version":"4.1.0"},"reference-count":15,"publisher":"Public Library of Science (PLoS)","issue":"2","license":[{"start":{"date-parts":[[2013,2,14]],"date-time":"2013-02-14T00:00:00Z","timestamp":1360800000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0056181","type":"journal-article","created":{"date-parts":[[2013,2,14]],"date-time":"2013-02-14T16:57:49Z","timestamp":1360861069000},"page":"e56181","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":28,"title":["Dysregulation of Multiple Facets of Glycogen Metabolism in a Murine Model of Pompe Disease"],"prefix":"10.1371","volume":"8","author":[{"given":"Kristin M.","family":"Taylor","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Meyers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Phipps","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priya S.","family":"Kishnani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seng H.","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald K.","family":"Scheule","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodney J.","family":"Moreland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2013,2,14]]},"reference":[{"key":"ref1","unstructured":"Engel AG, Hirschhorn R, Huie ML (2004) Acid Maltase Deficiency. Myology. 3rd ed. New York: McGraw-Hill. pp. 1559\u20131586."},{"key":"ref2","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1212\/01.wnl.0000252798.25690.76","article-title":"Broad spectrum of Pompe disease in patients with the same c.-32-13T-&gt;G haplotype","volume":"68","author":"MA Kroos","year":"2007","journal-title":"Neurology"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/S0960-8966(02)00186-4","article-title":"Effect of acid maltase deficiency on the endosomal\/lysosomal system and glucose transporter 4","volume":"13","author":"M Orth","year":"2003","journal-title":"Neuromuscul Disord"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1093\/hmg\/ddp535","article-title":"Restoration of muscle functionality by genetic suppression of glycogen synthesis in a murine model of Pompe disease","volume":"19","author":"G Douillard-Guilloux","year":"2010","journal-title":"Hum Mol Genet"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.ymgme.2010.05.001","article-title":"Inhibition of glycogen biosynthesis via mTORC1 suppression as an adjunct therapy for Pompe disease","volume":"100","author":"KM Ashe","year":"2010","journal-title":"Molecular Genetics and Metabolism"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"3112","DOI":"10.1128\/MCB.24.8.3112-3124.2004","article-title":"S6K1-\/-\/S6K2-\/- Mice Exhibit Perinatal Lethality and Rapamycin-Sensitive 5\u2032-Terminal Oligopyrimidine mRNA Translation and Reveal a Mitogen-Activated Protein Kinase-Dependent S6 Kinase Pathway","volume":"24","author":"M Pende","year":"2004","journal-title":"Mol Cell Biol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1006\/bbrc.2001.6292","article-title":"Inverse relationship of skeletal muscle glycogen from wild-type and genetically modified mice to their phosphorylase a activity","volume":"290","author":"LH Schliselfeld","year":"2002","journal-title":"Biochem Biophys Res Commun"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"23892","DOI":"10.1074\/jbc.M502344200","article-title":"Requirements for catalysis in mammalian glycogenin","volume":"280","author":"TD Hurley","year":"2005","journal-title":"J Biol Chem"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"3876","DOI":"10.1093\/hmg\/ddn290","article-title":"Modulation of glycogen synthesis by RNA interference: towards a new therapeutic approach for glycogenosis type II","volume":"17","author":"G Douillard-Guilloux","year":"2008","journal-title":"Hum Mol Genet"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1002\/ana.20807","article-title":"Dysfunction of endocytic and autophagic pathways in a lysosomal storage disease","volume":"59","author":"T Fukuda","year":"2006","journal-title":"Ann Neurol"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1016\/j.ymthe.2006.08.009","article-title":"Autophagy and mistargeting of therapeutic enzyme in skeletal muscle in Pompe disease","volume":"14","author":"T Fukuda","year":"2006","journal-title":"Mol Ther"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.4161\/auto.6.8.13378","article-title":"Suppression of autophagy permits successful enzyme replacement therapy in a lysosomal storage disorder\u2013murine Pompe disease","volume":"6","author":"N Raben","year":"2010","journal-title":"Autophagy"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"6780","DOI":"10.1074\/jbc.M404008200","article-title":"Lysosomal acid alpha-glucosidase consists of four different peptides processed from a single chain precursor","volume":"280","author":"RJ Moreland","year":"2005","journal-title":"J Biol Chem"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"19086","DOI":"10.1074\/jbc.273.30.19086","article-title":"Targeted Disruption of the Acid alpha -Glucosidase Gene in Mice Causes an Illness with Critical Features of Both Infantile and Adult Human Glycogen Storage Disease Type II","volume":"273","author":"N Raben","year":"1998","journal-title":"J Biol Chem"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.jchromb.2005.02.019","article-title":"A gel filtration assay to determine glycogen synthase activity","volume":"820","author":"A Niederwanger","year":"2005","journal-title":"J Chromatogr B Analyt Technol Biomed Life Sci"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0056181","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,10,19]],"date-time":"2018-10-19T23:38:30Z","timestamp":1539992310000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0056181"}},"subtitle":[],"editor":[{"given":"Michael","family":"M\u00fcller","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2013,2,14]]},"references-count":15,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2013,2,14]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0056181","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,2,14]]}}}