{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T12:53:15Z","timestamp":1760014395618},"reference-count":36,"publisher":"Public Library of Science (PLoS)","issue":"3","license":[{"start":{"date-parts":[[2013,3,13]],"date-time":"2013-03-13T00:00:00Z","timestamp":1363132800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0056708","type":"journal-article","created":{"date-parts":[[2013,3,13]],"date-time":"2013-03-13T22:52:07Z","timestamp":1363215127000},"page":"e56708","update-policy":"http:\/\/dx.doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":4,"title":["Identification of a Nonstructural DNA-Binding Protein (DBP) as an Antigen with Diagnostic Potential for Human Adenovirus"],"prefix":"10.1371","volume":"8","author":[{"given":"Li","family":"Guo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chengjun","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongli","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chao","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gl\u00e1ucia","family":"Paranhos-Baccal\u00e0","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guy","family":"Vernet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qi","family":"Jin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianwei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tao","family":"Hung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2013,3,13]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1016\/S0140-6736(95)91691-1","article-title":"Possible mechanism involving T-lymphocyte response to non-structural protein 3 in viral clearance in acute hepatitis C virus infection","volume":"346","author":"HM Diepolder","year":"1995","journal-title":"Lancet"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1016\/j.vaccine.2010.11.014","article-title":"Evaluation of a DNA vaccine candidate expressing prM-E-NS1 antigens of dengue virus serotype 1 with or without granulocyte-macrophage colony-stimulating factor (GM-CSF) in immunogenicity and protection","volume":"29","author":"Q Zheng","year":"2011","journal-title":"Vaccine"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1089\/aid.1990.6.1087","article-title":"Immunogenicity of the human immunodeficiency virus (HIV) recombinant nef gene product. Mapping of T-cell and B-cell epitopes in immunized chimpanzees","volume":"6","author":"E Bahraoui","year":"1990","journal-title":"AIDS Res Hum Retroviruses"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1128\/CVI.00371-06","article-title":"Antibody responses are generated to immunodominant ELK\/KLE-type motifs on the nonstructural-1 glycoprotein during live dengue virus infections in mice and humans: implications for diagnosis, pathogenesis, and vaccine design","volume":"14","author":"AK Falconar","year":"2007","journal-title":"Clin Vaccine Immunol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1002\/jgm.1144","article-title":"Protective vaccination with hepatitis C virus NS3 but not core antigen in a novel mouse challenge model","volume":"10","author":"S El-Gogo","year":"2008","journal-title":"J Gene Med"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"2895","DOI":"10.1099\/vir.0.19497-0","article-title":"Genetic content and evolution of adenoviruses","volume":"84","author":"AJ Davison","year":"2003","journal-title":"J Gen Virol"},{"key":"ref7","unstructured":"Wold WSM, Horwitz MS (2007) Adenoviridea: Adenovirus. In <italic>Fields Virology Volume 1<\/italic>. 5th edition. Knipe DM, Howley PM, editors. philadelphia: Lippincott WIllliams &amp; Wilkins. pp. 2396\u20132437."},{"key":"ref8","unstructured":"Shenk T (2001) Adenoviridae: the viruses and their replication. In: Knipe DM, Griffin DE, Lamb RA, Roizman B, Martin MA, Straus SE, editors. Fundamental virology, Baltimore: Lippincott Williams &amp; Wilkins, pp 1053\u20131088."},{"key":"ref9","doi-asserted-by":"crossref","first-page":"5978","DOI":"10.1128\/JVI.02650-06","article-title":"New adenovirus species found in a patient presenting with gastroenteritis","volume":"81","year":"2007","journal-title":"J Virol"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"4426","DOI":"10.1128\/JCM.43.9.4426-4433.2005","article-title":"Detection of antibodies against adenovirus protein IX, fiber, and hexon in human sera by immunoblot assay","volume":"43","author":"U Bauer","year":"2005","journal-title":"J Clin Microbiol"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1007\/s13238-012-2034-5","article-title":"Two-dimensional gel electrophoresis in bacterial proteomics","volume":"3","author":"SO Curreem","year":"2012","journal-title":"Protein Cell"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1021\/pr2007939","article-title":"Characterization of the Mycobacterium tuberculosis proteome by liquid chromatography mass spectrometry-based proteomics techniques: a comprehensive resource for tuberculosis research","volume":"11","author":"C Bell","year":"2012","journal-title":"J Proteome Res"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"e13915","DOI":"10.1371\/journal.pone.0013915","article-title":"Immunoproteomic analysis of human serological antibody responses to vaccination with whole-cell pertussis vaccine (WCV)","volume":"5","author":"YZ Zhu","year":"2010","journal-title":"PLoS One"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"2151","DOI":"10.1002\/pmic.200900557","article-title":"Immunoproteomic analyses of outer membrane proteins of Mannheimia haemolytica and identification of potential vaccine candidates","volume":"10","author":"S Ayalew","year":"2010","journal-title":"Proteomics"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"5080","DOI":"10.1128\/IAI.00701-09","article-title":"Immunoproteomic analysis of the development of natural immunity in subjects colonized by Neisseria meningitidis reveals potential vaccine candidates","volume":"77","author":"JN Williams","year":"2009","journal-title":"Infect Immun"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1186\/1471-2180-9-172","article-title":"Immunoproteomic analysis of outer membrane proteins and extracellular proteins of Actinobacillus pleuropneumoniae JL03 serotype 3","volume":"9","author":"Y Liao","year":"2009","journal-title":"BMC Microbiol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0014-5793(85)80381-1","article-title":"Characterization of the chymotryptic core of the adenovirus DNA-binding protein","volume":"188","author":"D Tsernoglou","year":"1985","journal-title":"FEBS Lett"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1007\/BF00370002","article-title":"Human adenovirus type 5 variants with sequence alterations flanking the E2A gene: effects on E2 expression and DNA replication","volume":"12","author":"C Caravokyri","year":"1996","journal-title":"Virus Genes"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"2289","DOI":"10.1128\/JVI.63.5.2289-2299.1989","article-title":"Isolation and characterization of a viable adenovirus mutant defective in nuclear transport of the DNA-binding protein","volume":"63","author":"V Cleghon","year":"1989","journal-title":"J Virol"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"8288","DOI":"10.1128\/JVI.68.12.8288-8295.1994","article-title":"Stimulation of the adenovirus major late promoter in vitro by transcription factor USF is enhanced by the adenovirus DNA binding protein","volume":"68","author":"DC Zijderveld","year":"1994","journal-title":"J Virol"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1023\/A:1008009630695","article-title":"A comparative analysis of the phosphorylation and biochemical properties of wild type and host range variant DNA binding proteins of human adenovirus 5","volume":"18","author":"E Harfst","year":"1999","journal-title":"Virus Genes"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/0042-6822(83)90474-9","article-title":"Host range temperature-conditional mutants in the adenovirus DNA binding protein are defective in the assembly of infectious virus","volume":"126","author":"JC Nicolas","year":"1983","journal-title":"Virology"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.jviromet.2012.05.021","article-title":"Improved sensitivity of influenza A antigen detection using a combined NP, M, and NS1 sandwich ELISA","volume":"185","author":"P Jian-umpunkul","year":"2012","journal-title":"J Virol Methods"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"E8","DOI":"10.1111\/j.1469-0691.2011.03694.x","article-title":"Evaluation and use of NS1 IgM antibody detection for acute dengue virus diagnosis: report from an outbreak investigation","volume":"18","author":"S Gowri Sankar","year":"2012","journal-title":"Clin Microbiol Infect"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1002\/hep.1840150228","article-title":"New kit on the block: evaluation of second-generation assays for detection of antibody to the hepatitis C virus","volume":"15","author":"HJ Alter","year":"1992","journal-title":"Hepatology"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1046\/j.1365-2893.2001.00280.x","article-title":"Sensitivity and specificity of third-generation hepatitis C virus antibody detection assays: an analysis of the literature","volume":"8","author":"C Colin","year":"2001","journal-title":"J Viral Hepat"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"S43","DOI":"10.1093\/cid\/cis368","article-title":"Laboratory diagnostics for hepatitis C virus infection","volume":"55","author":"S Kamili","year":"2012","journal-title":"Clin Infect Dis"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"596","DOI":"10.7326\/0003-4819-115-8-596","article-title":"Incidence of non-A, non-B hepatitis after screening blood donors for antibodies to hepatitis C virus and surrogate markers","volume":"115","author":"JM Barrera","year":"1991","journal-title":"Ann Intern Med"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1073\/pnas.92.5.1401","article-title":"Cellular and humoral immune responses to adenoviral vectors containing factor IX gene: tolerization of factor IX and vector antigens allows for long-term expression","volume":"92","author":"Y Dai","year":"1995","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"6729","DOI":"10.1128\/JVI.73.8.6729-6742.1999","article-title":"Variability of human systemic humoral immune responses to adenovirus gene transfer vectors administered to different organs","volume":"73","author":"BG Harvey","year":"1999","journal-title":"J Virol"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"7179","DOI":"10.4049\/jimmunol.174.11.7179","article-title":"Neutralizing antibodies to adenovirus serotype 5 vaccine vectors are directed primarily against the adenovirus hexon protein","volume":"174","author":"SM Sumida","year":"2005","journal-title":"J Immunol"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.jviromet.2011.06.016","article-title":"Generation of a replication-deficient recombinant human adenovirus type 35 vector using bacteria-mediated homologous recombination","volume":"177","author":"C Wu","year":"2011","journal-title":"J Virol Methods"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1186\/1743-422X-8-62","article-title":"Large-scale seroprevalence analysis of human metapneumovirus and human respiratory syncytial virus infections in Beijing, China","volume":"8","author":"G Lu","year":"2011","journal-title":"Virol J"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1128\/JCM.39.2.498-505.2001","article-title":"Rapid typing of human adenoviruses by a general PCR combined with restriction endonuclease analysis","volume":"39","author":"A Allard","year":"2001","journal-title":"J Clin Microbiol"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"1596","DOI":"10.1093\/molbev\/msm092","article-title":"MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0","volume":"24","author":"K Tamura","year":"2007","journal-title":"Mol Biol Evol"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1136\/bmj.327.7417.716","article-title":"Understanding sensitivity and specificity with the right side of the brain","volume":"327","author":"TW Loong","year":"2003","journal-title":"BMJ"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0056708","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,23]],"date-time":"2020-07-23T21:37:37Z","timestamp":1595540257000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0056708"}},"subtitle":[],"editor":[{"given":"Herman","family":"Tse","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2013,3,13]]},"references-count":36,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2013,3,13]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0056708","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,3,13]]}}}