{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T20:59:41Z","timestamp":1773694781007,"version":"3.50.1"},"reference-count":39,"publisher":"Public Library of Science (PLoS)","issue":"3","license":[{"start":{"date-parts":[[2013,3,14]],"date-time":"2013-03-14T00:00:00Z","timestamp":1363219200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0058132","type":"journal-article","created":{"date-parts":[[2013,3,14]],"date-time":"2013-03-14T23:48:24Z","timestamp":1363304904000},"page":"e58132","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":23,"title":["Phenotypes and Karyotypes of Human Malignant Mesothelioma Cell Lines"],"prefix":"10.1371","volume":"8","author":[{"given":"Vandana","family":"Relan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leanne","family":"Morrison","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kylie","family":"Parsonson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Belinda E.","family":"Clarke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edwina E.","family":"Duhig","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Morgan N.","family":"Windsor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin S.","family":"Matar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rishendran","family":"Naidoo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda","family":"Passmore","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth","family":"McCaul","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deborah","family":"Courtney","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ian A.","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kwun M.","family":"Fong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rayleen V.","family":"Bowman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2013,3,14]]},"reference":[{"key":"ref1","unstructured":"Safe work Australia (2009 ) Mesothelioma in Australia - INCIDENCE 1982 TO 2005, DEATHS 1997 TO 2006; Mesothelioma in Australia,."},{"key":"ref2","doi-asserted-by":"crossref","unstructured":"Bianchi CBT (2007) Malignant mesothelioma: global incidence and relationship with asbestos. Industrial Health 45 379\u2013387.","DOI":"10.2486\/indhealth.45.379"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"144","DOI":"10.18773\/austprescr.2011.076","article-title":"Medical management of mesothelioma","volume":"5","author":"RRV Bowman","year":"2011","journal-title":"Australian Prescriber 34"},{"key":"ref4","doi-asserted-by":"crossref","unstructured":"Sato G (2008) Tissue culture: the unrealized potential. Cytotechnology 57.","DOI":"10.1007\/s10616-007-9109-9"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1007\/s11626-010-9315-1","article-title":"Tissue culture: the unlimited potential","volume":"46","author":"GH Sato","year":"2010","journal-title":"In Vitro Cell Dev Biol Anim"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"2384","DOI":"10.1128\/MCB.25.6.2384-2394.2005","article-title":"The NF2 tumor suppressor gene product, merlin, inhibits cell proliferation and cell cycle progression by repressing cyclin D1 expression","volume":"25","author":"GR Xiao GH","year":"2005","journal-title":"Mol Cell Biol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1016\/j.bbrc.2009.03.042","article-title":"Tumorigenic properties of alternative osteopontin isoforms in mesothelioma","volume":"382","author":"IA Ivanov SV","year":"2009","journal-title":"Biochem Biophys Res Commun"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1159\/000113504","article-title":"Characterization of human mesothelioma cell lines as tumor models for suicide gene therapy","volume":"31","author":"MR Veldwijk","year":"2008","journal-title":"Onkologie"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1002\/ijc.2910470219","article-title":"Establishment and characterization of five human malignant mesothelioma cell lines derived from pleural effusions","volume":"47","author":"LS Manning","year":"1991","journal-title":"Int J Cancer"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1111\/j.1349-7006.2006.00184.x","article-title":"Establishment and characterization of four malignant pleural mesothelioma cell lines from Japanese patients","volume":"97","author":"N Usami","year":"2006","journal-title":"Cancer Sci"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1007\/s00418-004-0701-1","article-title":"Establishment of permanent cell lines purified from human mesothelioma: morphological aspects, new marker expression and karyotypic analysis","volume":"122","author":"MM Philippeaux","year":"2004","journal-title":"Histochem Cell Biol"},{"key":"ref12","unstructured":"Roth V (2006) <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.doubling-time.com\/compute.php\" xlink:type=\"simple\">http:\/\/www.doubling-time.com\/compute.php<\/ext-link>.Accessed 2012, Feb."},{"key":"ref13","first-page":"2796","article-title":"Anchorage-independent cell growth signature identifies tumorswith metastatic potential Oncogene","volume":"28","author":"S ori","year":"2009"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"4233","DOI":"10.1158\/0008-5472.CAN-09-3470","article-title":"Phospholipase D1 Drives a Positive Feedback Loop to Reinforce the Wnt\/b-Catenin\/TCF Signaling Axis","volume":"70","author":"S-HL Dong Woo Kang","year":"2010","journal-title":"Cancer Res"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1586\/14737159.5.5.715","article-title":"Malignant mesothelioma: current status of histopathologic diagnosis and molecular profile","volume":"5","author":"S Suster","year":"2005","journal-title":"Expert Rev Mol Diagn"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1007\/BF02624162","article-title":"Terminology associated with cell, tissue, and organ culture, molecular biology, and molecular genetics. Tissue Culture Association Terminology Committee","volume":"26","author":"WI Schaffer","year":"1990","journal-title":"In Vitro Cell Dev Biol"},{"key":"ref17","unstructured":"Gazdar AF, Carney DN, Guccion JG, Baylin SB (1981) Small cell carcinoma of the lung: Cellular origin and relationship to other pulmonary tumors,. In Greco, F A, Oldham, R K and Bunn,P A (eds), Small cell carcinoma of the lung, Grune &amp; Stratton, New York,: 145\u2013175."},{"key":"ref18","doi-asserted-by":"crossref","unstructured":"Pass HI SE, Oie H, Tsokos MG, Abati AD, Fetsch PA, et al..(1995) Characteristics of nine newly derived mesothelioma cell lines.. Ann Thorac Surg 59.","DOI":"10.1016\/0003-4975(95)00045-M"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1093\/carcin\/11.4.673","article-title":"Asbestos-related malignant mesothelioma: growth, cytology, tumorigenicity and consistent chromosome findings in cell lines from five patients","volume":"11","author":"K Pelin-Enlund","year":"1990","journal-title":"Carcinogenesis"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/S0092-8674(00)81683-9","article-title":"The hallmarks of cancer","volume":"100","author":"D Hanahan","year":"2000","journal-title":"Cell"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/0092-8674(74)90050-6","article-title":"Cellular tumorigenicity in nude mice: correlation with cell growth in semi-solid medium","volume":"3","author":"VH Freedman","year":"1974","journal-title":"Cell"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"397","DOI":"10.5858\/2008-132-397-AOITTD","article-title":"Application of immunohistochemistry to the diagnosis of malignant mesothelioma","volume":"132","author":"AM Marchevsky","year":"2008","journal-title":"Arch Pathol Lab Med"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1016\/j.biocel.2003.11.002","article-title":"Mesothelial progenitor cells and their potential in tissue engineering","volume":"36","author":"SE Herrick","year":"2004","journal-title":"The International Journal of Biochemistry & Cell Biology"},{"key":"ref24","doi-asserted-by":"crossref","unstructured":"Hiyama J, Marukawa M, Shiota Y, Ono T, Imai S, et al.. (1998) Two familial mesothelioma cases with high concentrations of soluble cytokeratin 19 fragment in pleural fluid. Intern Med 37.","DOI":"10.2169\/internalmedicine.37.407"},{"key":"ref25","first-page":"4343","article-title":"Cytokeratin 19 fragment\/carcinoembryonic antigen ratio in pleural effusion is a useful marker for detecting malignant pleural mesothelioma","volume":"30","author":"H Suzuki","year":"2010","journal-title":"Anticancer Res"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1183\/09031936.99.13352799","article-title":"Establishment of four new mesothelioma cell lines: characterization by ultrastructural and immunophenotypic analysis","volume":"13","author":"AM Orengo","year":"1999","journal-title":"Eur Respir J"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1038\/nm0897-908","article-title":"Simian virus-40 large-T antigen binds p53 in human mesotheliomas","volume":"3","author":"M Carbone","year":"1997","journal-title":"Nat Med"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/0165-4608(83)90070-5","article-title":"A chromosomal hypothesis of oncogenesis","volume":"8","year":"1983","journal-title":"Cancer Genet Cytogenet"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/0165-4608(88)90035-0","article-title":"Nonrandom chromosomal abnormalities in malignant pleural mesothelioma","volume":"33","author":"M Tiainen","year":"1988","journal-title":"Cancer Genet Cytogenet"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1038\/bjc.1997.91","article-title":"Recurrent DNA copy number changes in 1q, 4q, 6q, 9p, 13q, 14q and 22q detected by comparative genomic hybridization in malignant mesothelioma","volume":"75","author":"AM Bj\u00f6rkqvist","year":"1997","journal-title":"Br J Cancer"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1510\/icvts.2008.201509","article-title":"Chromosomal deletion in patients with malignant pleural mesothelioma","volume":"9","author":"S Neragi-Miandoab","year":"2009","journal-title":"Interact CardioVasc Thorac Surg"},{"key":"ref32","first-page":"955","article-title":"Concurrent LOH at multiple loci in human malignant mesothelioma with preferential loss of NF2 gene region","volume":"9","author":"SM Pylkkanen L","year":"2002","journal-title":"Oncol Rep"},{"key":"ref33","first-page":"1495","article-title":"Guidelines for the Use of Cell Lines in Cancer Research","volume":"82","year":"2000","journal-title":"British Journal of Cancer"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.lungcan.2004.04.005","article-title":"Pathological anatomy and molecular pathology","volume":"45","author":"M Krismann","year":"2004","journal-title":"Lung Cancer"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1159\/000109618","article-title":"Gene copy number analysis in malignant pleuralmesothelioma using oligonucleotide array CGH","volume":"119","author":"PM Lindholm","year":"2007","journal-title":"Cytogenet Genome Res"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1038\/bjc.1989.326","article-title":"Chromosomal abnormalities and their correlations with asbestos exposure and survival in patients with mesothelioma","volume":"60","author":"M Tiainen","year":"1989","journal-title":"Br J Cancer"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"10819","DOI":"10.1073\/pnas.92.24.10819","article-title":"Asbestos and mesothelioma: Genetic lessons from a tragedy","volume":"92","author":"A Knudson","year":"1995","journal-title":"Proc Natl Acad Sci"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1007\/s10540-005-2797-5","article-title":"Comparison of established cell lines at different passages by karyotype and comparative genomic hybridization","volume":"24","author":"SL Wenger","year":"2004","journal-title":"Biosci Rep"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1002\/gcc.20475","article-title":"Gene expression profiling and gene copy-number changes in malignant mesothelioma cell lines","volume":"46","author":"C Zanazzi","year":"2007","journal-title":"Genes Chromosomes Cancer"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0058132","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,11]],"date-time":"2022-02-11T13:56:05Z","timestamp":1644587765000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0058132"}},"subtitle":[],"editor":[{"given":"Rajasingh","family":"Johnson","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2013,3,14]]},"references-count":39,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2013,3,14]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0058132","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,3,14]]}}}