{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,7]],"date-time":"2026-06-07T10:07:09Z","timestamp":1780826829601,"version":"3.54.1"},"reference-count":29,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2013,4,9]],"date-time":"2013-04-09T00:00:00Z","timestamp":1365465600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0060848","type":"journal-article","created":{"date-parts":[[2013,4,9]],"date-time":"2013-04-09T21:06:29Z","timestamp":1365541589000},"page":"e60848","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":24,"title":["Epidemiology of Streptococcus pneumoniae Serogroup 6 Isolates from IPD in Children and Adults in Germany"],"prefix":"10.1371","volume":"8","author":[{"given":"Mark","family":"van der Linden","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadine","family":"Winkel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon","family":"K\u00fcntzel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aron","family":"Farkas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie Russo","family":"Perniciaro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralf Ren\u00e9","family":"Reinert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Im\u00f6hl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2013,4,9]]},"reference":[{"key":"ref1","first-page":"129","article-title":"Pneumococcal vaccines - WHO position paper 2012","volume":"87","year":"2012","journal-title":"Weekly Epidemiology Records"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"4482","DOI":"10.1128\/IAI.00510-07","article-title":"Genetic basis for the new pneumococcal serotype, 6C","volume":"75","author":"IH Park","year":"2007","journal-title":"Infect Immun"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1099\/mic.0.024521-0","article-title":"Production of a unique pneumococcal capsule serotype belonging to serogroup 6","volume":"155","author":"PE Bratcher","year":"2009","journal-title":"Microbiology"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1086\/606118","article-title":"First Report of Putative Streptococcus pneumoniae Serotype 6D among Nasopharyngeal Isolates from Fijian Children","volume":"200","author":"P Jin","year":"2009","journal-title":"J Infect Dis"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1099\/mic.0.034116-0","article-title":"Identification of natural pneumococcal isolates expressing serotype 6D by genetic, biochemical and serological characterization","volume":"156","author":"PE Bratcher","year":"2010","journal-title":"Microbiology"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"4298","DOI":"10.1128\/JCM.00861-10","article-title":"Molecular epidemiology of Streptococcus pneumoniae serogroup 6 isolates from Fijian children, including newly identified serotypes 6C and 6D","volume":"48","author":"C Satzke","year":"2010","journal-title":"J Clin Microbiol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"8181","DOI":"10.1128\/JB.186.24.8181-8192.2004","article-title":"Evolutionary genetics of the capsular locus of serogroup 6 pneumococci","volume":"186","author":"A Mavroidi","year":"2004","journal-title":"J Bacteriol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1056\/NEJMoa022823","article-title":"Decline in invasive pneumococcal disease after the introduction of protein-polysaccharide conjugate vaccine","volume":"348","author":"CG Whitney","year":"2003","journal-title":"N Engl J Med"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1086\/315096","article-title":"Immunity to cross-reactive serotypes induced by pneumococcal conjugate vaccines in infants","volume":"180","author":"X Yu","year":"1999","journal-title":"J Inf Dis"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"1818","DOI":"10.1086\/593339","article-title":"Differential effects of pneumococcal vaccines against serotypes 6A and 6C","volume":"198","author":"IH Park","year":"2008","journal-title":"J Infect Dis"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1128\/JCM.01919-08","article-title":"PCR-based quantitation and clonal diversity of the current prevalent invasive serogroup 6 pneumococcal serotype, 6C, in the United States in 1999 and 2006 to 2007","volume":"47","author":"G Carvalho Mda","year":"2009","journal-title":"J Clin Microbiol"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"7207","DOI":"10.1016\/j.vaccine.2011.06.056","article-title":"The 13-valent pneumococcal conjugate vaccine (PCV13) elicits cross-functional opsonophagocytic killing responses in humans to Streptococcus pneumoniae serotypes 6C and 7A","volume":"29","author":"D Cooper","year":"2011","journal-title":"Vaccine"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1097\/INF.0b013e318247ef84","article-title":"Impact of 13-valent pneumococcal conjugate vaccine on pneumococcal nasopharyngeal carriage in children with acute otitis media","volume":"31","author":"R Cohen","year":"2012","journal-title":"Pediatr Infect Dis J"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1097\/INF.0b013e318187e215","article-title":"Association of serotype of Streptococcus pneumoniae with risk of severe and fatal outcome","volume":"28","author":"S R\u00fcckinger","year":"2009","journal-title":"Pediatr Infect Dis J"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.1128\/JCM.01937-09","article-title":"Association of serotypes of Streptococcus pneumoniae with age in invasive pneumococcal disease","volume":"48","author":"M Im\u00f6hl","year":"2010","journal-title":"J Clin Microbiol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"2470","DOI":"10.1128\/JCM.00484-09","article-title":"Simple, accurate, serotype-specific PCR assay to differentiate Streptococcus pneumoniae serotypes 6A, 6B, and 6C","volume":"47","author":"P Jin","year":"2009","journal-title":"J Clin Microbiol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1099\/mic.0.043901-0","article-title":"Evolution of the capsular gene locus of Streptococcus pneumoniae serogroup 6","volume":"157","author":"PE Bratcher","year":"2011","journal-title":"Microbiology"},{"key":"ref18","unstructured":"Clinical Laboratory Standards Institute (2011) Performance standards for antimicrobial susceptibility testing; Twenty-first Informational Supplement M100-S21 Institute CLS, editor. Wayne, PA."},{"key":"ref19","doi-asserted-by":"crossref","first-page":"3049","DOI":"10.1099\/00221287-144-11-3049","article-title":"A multilocus sequence typing scheme for <italic>Streptococcus pneumoniae<\/italic> identification of clones associated with serious invasive disease","volume":"144","author":"MC Enright","year":"1998","journal-title":"Microbiology"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1186\/1471-2180-10-299","article-title":"Macrolide susceptibility and serotype specific macrolide resistance of invasive isolates of Streptococcus pneumoniae in Germany from 1992 to 2008","volume":"10","author":"M Im\u00f6hl","year":"2011","journal-title":"BMC Microbiol"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"1712","DOI":"10.1093\/jac\/dkr193","article-title":"Trends of invasive serotype 6C pneumococci in Spain: emergence of a new lineage","volume":"66","author":"D Rolo","year":"2011","journal-title":"J Antimicrob Chemother"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"6406","DOI":"10.1016\/j.vaccine.2010.07.051","article-title":"First report of Streptococcus pneumoniae serotype 6D isolates from invasive infections","volume":"28","author":"A Kuch","year":"2010","journal-title":"Vaccine"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1099\/jmm.0.023853-0","article-title":"A report of Streptococcus pneumoniae serotype 6D in Europe","volume":"60","author":"MH Nahm","year":"2011","journal-title":"J Med Microbiol"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"1751","DOI":"10.3201\/eid1611.100941","article-title":"Prevalence and genetic structures of Streptococcus pneumoniae serotype 6D, South Korea","volume":"16","author":"EH Choi","year":"2010","journal-title":"Emerg Infect Dis"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1056\/NEJMoa051642","article-title":"Effect of introduction of the pneumococcal conjugate vaccine on drug-resistant Streptococcus pneumoniae","volume":"354","author":"MH Kyaw","year":"2006","journal-title":"N Engl J Med"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"1212","DOI":"10.1099\/jmm.0.022954-0","article-title":"Antibiotic resistance in invasive Streptococcus pneumoniae isolates identified in Scotland between 1999 and 2007","volume":"59","author":"B Cooke","year":"2010","journal-title":"J Med Microbiol"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1128\/JCM.01454-08","article-title":"Temporal trends of invasive Streptococcus pneumoniae serotypes and antimicrobial resistance patterns in Spain from 1979 to 2007","volume":"47","author":"A Fenoll","year":"2009","journal-title":"J Clin Microbiol"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"2328","DOI":"10.1128\/JCM.02545-10","article-title":"Characterization of invasive Pneumococci of serogroup 6 from adults in Barcelona, Spain, in 1994 to 2008","volume":"49","author":"D Rolo","year":"2011","journal-title":"J Clin Microbiol"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1128\/JCM.01524-08","article-title":"Occurrence, distribution, and origins of Streptococcus pneumoniae Serotype 6C, a recently recognized serotype","volume":"47","author":"MR Jacobs","year":"2009","journal-title":"J Clin Microbiol"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0060848","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,9]],"date-time":"2020-05-09T16:36:56Z","timestamp":1589042216000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0060848"}},"subtitle":[],"editor":[{"given":"Bernard","family":"Beall","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2013,4,9]]},"references-count":29,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2013,4,9]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0060848","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,4,9]]}}}