{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T06:22:28Z","timestamp":1780640548015,"version":"3.54.1"},"reference-count":33,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2013,4,1]],"date-time":"2013-04-01T00:00:00Z","timestamp":1364774400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0060946","type":"journal-article","created":{"date-parts":[[2013,4,1]],"date-time":"2013-04-01T21:05:33Z","timestamp":1364850333000},"page":"e60946","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":28,"title":["Implications of Discordance in World Health Organization 1997 and 2009 Dengue Classifications in Adult Dengue"],"prefix":"10.1371","volume":"8","author":[{"given":"Victor C.","family":"Gan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David C.","family":"Lye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tun L.","family":"Thein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederico","family":"Dimatatac","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriana S.","family":"Tan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yee-Sin","family":"Leo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2013,4,1]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"S7","DOI":"10.1038\/nrmicro2460","article-title":"Dengue: a continuing global threat","volume":"8","author":"MG Guzman","year":"2010","journal-title":"Nat Rev Microbiol"},{"key":"ref2","article-title":"Dengue haemorrhagic fever: diagnosis, treatment, prevention and control. 2nd edition","year":"1997","journal-title":"Geneva"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1016\/S0140-6736(95)91771-3","article-title":"Changing epidemiology of dengue in Singapore","volume":"346","author":"KT Goh","year":"1995","journal-title":"Lancet"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"e1000139","DOI":"10.1371\/journal.pmed.1000139","article-title":"The Impact of the Demographic Transition on Dengue in Thailand: Insights from a Statistical Analysis and Mathematical Modeling","volume":"6","author":"DAT Cummings","year":"2009","journal-title":"PLoS Med"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"924","DOI":"10.3201\/eid1306.070008","article-title":"Age and clinical dengue illness","volume":"13","author":"JR Egger","year":"2007","journal-title":"Emerging Infect Dis"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1016\/j.jcv.2005.03.002","article-title":"An outbreak of primary dengue infection among migrant Chinese workers in Singapore characterized by prominent gastrointestinal symptoms and a high proportion of symptomatic cases","volume":"33","author":"RCS Seet","year":"2005","journal-title":"J Clin Virol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/S0140-6736(02)09481-3","article-title":"Encephalitis and dengue","volume":"360","author":"EJ Garc\u00eda-Rivera","year":"2002","journal-title":"Lancet"},{"key":"ref8","article-title":"Comprehensive Guidelines for Prevention and Control of Dengue and Dengue Haemorrhagic Fever: Revised and expanded edition","year":"2011","journal-title":"New Delhi, India: World Health Organization"},{"key":"ref9","unstructured":"World Health Organization (2009) Dengue: guidelines for diagnosis, treatment, prevention and control. New ed. Geneva: World Health Organization. p."},{"key":"ref10","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.inhe.2009.08.006","article-title":"Comparison and critical appraisal of dengue clinical guidelines and their use in Asia and Latin America","volume":"1","author":"R Santamaria","year":"2009","journal-title":"International Health"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"166","DOI":"10.4269\/ajtmh.2012.11-0491","article-title":"Evaluation of the 2009 WHO dengue case classification in an Indonesian pediatric cohort","volume":"86","author":"CAM Van de Weg","year":"2012","journal-title":"Am J Trop Med Hyg"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"e1397","DOI":"10.1371\/journal.pntd.0001397","article-title":"Evaluation of the traditional and revised WHO classifications of Dengue disease severity","volume":"5","author":"F Narvaez","year":"2011","journal-title":"PLoS Negl Trop Dis"},{"key":"ref13","first-page":"S74","article-title":"Dengue classification: current WHO vs. the newly suggested classification for better clinical application?","volume":"94","author":"S Kalayanarooj","year":"2011","journal-title":"J Med Assoc Thai"},{"key":"ref14","article-title":"Multicentre prospective study on dengue classification in four South-east Asian and three Latin American countries","author":"N Alexander","year":"2011","journal-title":"Trop Med Int Health"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1093\/cid\/cir451","article-title":"Dengue--how best to classify it","volume":"53","author":"A Srikiatkhachorn","year":"2011","journal-title":"Clin Infect Dis"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/S1473-3099(06)70465-0","article-title":"Severe dengue: the need for new case definitions","volume":"6","author":"JG Rigau-P\u00e9rez","year":"2006","journal-title":"Lancet Infect Dis"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"847","DOI":"10.3201\/eid1605.091006","article-title":"Dengue virus surveillance for early warning, Singapore","volume":"16","author":"KS Lee","year":"2010","journal-title":"Emerging Infect Dis"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.trstmh.2005.05.015","article-title":"The performance of RT-PCR compared with a rapid serological assay for acute dengue fever in a diagnostic laboratory","volume":"100","author":"TM Barkham","year":"2006","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"R31","DOI":"10.1186\/cc5713","article-title":"Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury","volume":"11","author":"RL Mehta","year":"2007","journal-title":"Crit Care"},{"key":"ref20","first-page":"41","article-title":"Changing Pattern of Dengue Transmission in Singapore","volume":"25","author":"EE Ooi","year":"2001","journal-title":"Dengue Bulletin"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"224","DOI":"10.4269\/ajtmh.2011.10-0316","article-title":"Evaluation of the NS1 Rapid Test and the WHO Dengue Classification Schemes for Use as Bedside Diagnosis of Acute Dengue Fever in Adults","volume":"84","author":"S Chaterji","year":"2011","journal-title":"Am J Trop Med Hyg"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"e1191","DOI":"10.1371\/journal.pntd.0001191","article-title":"The early clinical features of dengue in adults: challenges for early clinical diagnosis","volume":"5","author":"JGH Low","year":"2011","journal-title":"PLoS Negl Trop Dis"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"1238","DOI":"10.1111\/j.1365-3156.2006.01678.x","article-title":"Classifying dengue: a review of the difficulties in using the WHO case classification for dengue haemorrhagic fever","volume":"11","author":"S Bandyopadhyay","year":"2006","journal-title":"Trop Med Int Health"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1186\/1471-2334-11-106","article-title":"Usefulness and applicability of the revised dengue case classification by disease: multi-centre study in 18 countries","volume":"11","author":"J Barniol","year":"2011","journal-title":"BMC Infect Dis"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"e1676","DOI":"10.1371\/journal.pntd.0001676","article-title":"Clinical relevance and discriminatory value of elevated liver aminotransferase levels for dengue severity","volume":"6","author":"LK Lee","year":"2012","journal-title":"PLoS Negl Trop Dis"},{"key":"ref26","unstructured":"Ministry of Health, Singapore (2005) Communicable diseases surveillance in Singapore 2004."},{"key":"ref27","first-page":"44","article-title":"Management guidelines for dengue patients at Tan Tock Seng Hospital and the Communicable Diseases Centre, Singapore 2005","volume":"31","author":"D Lye","year":"2005","journal-title":"Epidemiological News Bulletin"},{"key":"ref28","first-page":"476","article-title":"Do young adults with uncomplicated dengue fever need hospitalisation? A retrospective analysis of clinical and laboratory features","volume":"49","author":"DC Lye","year":"2008","journal-title":"Singapore Med J"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.trstmh.2008.07.007","article-title":"Dengue management: practical and safe hospital-based outpatient care","volume":"103","author":"PR Ingram","year":"2009","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.jcv.2007.12.017","article-title":"Predictive value of simple clinical and laboratory variables for dengue hemorrhagic fever in adults","volume":"42","author":"VJ Lee","year":"2008","journal-title":"J Clin Virol"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1111\/j.1365-3156.2009.02337.x","article-title":"Decision tree algorithm in deciding hospitalization for adult patients with dengue haemorrhagic fever in Singapore","volume":"14","author":"VJ Lee","year":"2009","journal-title":"Trop Med Int Health"},{"key":"ref32","article-title":"Safety and cost savings of reducing adult dengue hospitalization in a tertiary care hospital","author":"LK Lee","year":"2012","journal-title":"Transactions of the Royal Society of Tropical Medicine and Hygiene: in press"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1002\/hep.20703","article-title":"AASLD position paper: the management of acute liver failure","volume":"41","author":"J Polson","year":"2005","journal-title":"Hepatology"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0060946","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,9]],"date-time":"2020-05-09T09:30:30Z","timestamp":1589016630000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0060946"}},"subtitle":[],"editor":[{"given":"Nikos","family":"Vasilakis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2013,4,1]]},"references-count":33,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2013,4,1]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0060946","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,4,1]]}}}