{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T03:53:42Z","timestamp":1783655622420,"version":"3.55.0"},"reference-count":44,"publisher":"Public Library of Science (PLoS)","issue":"5","license":[{"start":{"date-parts":[[2013,5,15]],"date-time":"2013-05-15T00:00:00Z","timestamp":1368576000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0062259","type":"journal-article","created":{"date-parts":[[2013,5,15]],"date-time":"2013-05-15T21:46:20Z","timestamp":1368654380000},"page":"e62259","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":58,"title":["Pandemic H1N1 Influenza Isolated from Free-Ranging Northern Elephant Seals in 2010 off the Central California Coast"],"prefix":"10.1371","volume":"8","author":[{"given":"Tracey","family":"Goldstein","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ignacio","family":"Mena","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon J.","family":"Anthony","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafael","family":"Medina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick W.","family":"Robinson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denise J.","family":"Greig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel P.","family":"Costa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W. Ian","family":"Lipkin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adolfo","family":"Garcia-Sastre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Walter M.","family":"Boyce","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2013,5,15]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1128\/JVI.51.3.863-865.1984","article-title":"Are seals frequently infected with avian influenza viruses?","volume":"51","author":"VS Hinshaw","year":"1984","journal-title":"J Virol"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1056\/NEJM198104093041515","article-title":"Conjunctivitis in human beings caused by influenza A virus of seals","volume":"304","author":"RG Webster","year":"1981","journal-title":"N Engl J Med"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/0042-6822(90)90250-U","article-title":"Derivation of the nucleoproteins (NP) of influenza A viruses isolated from marine mammals","volume":"176","author":"J Mandler","year":"1990","journal-title":"Virol"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1126\/science.7063847","article-title":"Mass mortality of harbor seals: Pneumonia associated with influenza virus","volume":"215","author":"JR Geraci","year":"1982","journal-title":"Science"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"e00166","DOI":"10.1128\/mBio.00166-12","article-title":"Emergence of Fatal Avian Influenza in New England Harbor Seals","volume":"3","author":"SJ Anthony","year":"2012","journal-title":"MBio"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1007\/BF01314571","article-title":"Isolation of an influenza A virus from seals","volume":"68","author":"G Lang","year":"1981","journal-title":"Arch Virol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1099\/0022-1317-76-1-199","article-title":"The appearance of H3 influenza viruses in seals","volume":"76","author":"RJ Callan","year":"1995","journal-title":"J Gen Virol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1128\/JVI.58.2.655-656.1986","article-title":"Characterization of two influenza A viruses from a pilot whale","volume":"58","author":"VS Hinshaw","year":"1986","journal-title":"J Virol"},{"key":"ref9","first-page":"502","article-title":"Serological investigation of virus infections in harp seals (<italic>Phoca groenlandica<\/italic>) and hooded seals (<italic>Cystophora cristata<\/italic>)","volume":"Rec134","author":"S Steuen","year":"1994","journal-title":"Vet"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"820","DOI":"10.7589\/0090-3558-37.4.820","article-title":"Serologic Evidence of Influenza A Infection in Marine Mammals of Arctic Canada","volume":"37","author":"O Nielsen","year":"2001","journal-title":"J Wildl Dis"},{"key":"ref11","unstructured":"Greig D (2011) Health, Disease, Mortality and Survival in wild and rehabilitated harbor seals (<italic>Phoca vitulina<\/italic>) in San Francisco Bay and along the central California coast. Dissertation Thesis. Available: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/hdl.handle.net\/10023\/1885\" xlink:type=\"simple\">http:\/\/hdl.handle.net\/10023\/1885<\/ext-link>. Accessed 2013 Apr 23."},{"key":"ref12","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1111\/j.1748-7692.1998.tb00730.x","article-title":"Serologic evidence of influenza virus infection in a ringed seal (<italic>Phoca hispida<\/italic>) from Alaska","volume":"14","author":"GR Danner","year":"2006","journal-title":"Mar Mamm Sci"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1111\/j.1348-0421.2002.tb02746.x","article-title":"Serological evidence of transmission of human influenza A and B viruses to Caspian seals (<italic>Phoca caspica<\/italic>)","volume":"46","author":"K Ohishi","year":"2002","journal-title":"Microbiol Immunol"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1111\/j.1348-0421.2004.tb03610.x","article-title":"Antibodies to human-related H3 influenza A virus in Baikal seals (<italic>Phoca sibirica<\/italic>) and ringed seals (<italic>Phoca hispida<\/italic>) in Russia","volume":"48","author":"K Ohishi","year":"2004","journal-title":"Microbiol Immunol"},{"key":"ref15","first-page":"e36728","article-title":"Foraging Behavior and Success of a Mesopelagic Predator in the Northeast Pacific Ocean: Insights from a Data-Rich Species, the Northern Elephant Seal PLoS ONE Volume","volume":"7","author":"PW Robinson","year":"2012"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1890\/0012-9615(2000)070[0353:FEONES]2.0.CO;2","article-title":"Foraging ecology of Northern elephant seals","volume":"70","author":"BJ Le Boeuf","year":"2000","journal-title":"Ecol Mono"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1038\/nature10082","article-title":"Tracking apex marine predator movements in a dynamic ocean","volume":"475","author":"BA Block","year":"2011","journal-title":"Nature"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"1901","DOI":"10.1007\/s00705-007-0994-1","article-title":"Using RRT-PCR analysis and virus isolation to determine the prevalence of avian influenza virus infections in ducks at Minto Flats Refuge, Alaska, during August 2005","volume":"152","author":"J Runstadler","year":"2007","journal-title":"Arch Virol"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1186\/1471-2148-7-214","article-title":"BEAST: Bayesian evolutionary analysis by sampling trees","volume":"7","author":"AJ Drummond","year":"2007","journal-title":"BMC Evol Biol"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1038\/nature06945","article-title":"The genomic and epidemiological dynamics of human influenza A virus","volume":"453","author":"A Rambaut","year":"2008","journal-title":"Nature"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"11709","DOI":"10.1073\/pnas.0904991106","article-title":"Dating the emergence of pandemic influenza viruses","volume":"106","author":"GJD Smith","year":"2009","journal-title":"PNAS"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1128\/JVI.05347-11","article-title":"Evolutionary Dynamics of Local Pandemic H1N1\/2009 Influenza Virus Lineages Revealed by Whole-Genome Analysis","volume":"86","author":"GJ Baillie","year":"2011","journal-title":"J Virol"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"11531","DOI":"10.1073\/pnas.0914994107","article-title":"Analysis of in vivo dynamics of influenza virus infection in mice using a GFP reporter virus","volume":"107","author":"B Manicassamy","year":"2010","journal-title":"Proc Natl Acad Sci USA"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"e1000745","DOI":"10.1371\/journal.ppat.1000745","article-title":"Protection of Mice against Lethal Challenge with 2009 H1N1 Influenza A Virus by 1918-Like and Classical Swine H1N1 Based Vaccines","volume":"6","author":"B Manicassamy","year":"2010","journal-title":"PLoS Pathog"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/ncomms1026","article-title":"Pandemic 2009 H1N1 vaccine protects against 1918 Spanish influenza virus","volume":"1(3)","author":"RA Medina","year":"2010","journal-title":"Nat Commun"},{"key":"ref26","first-page":"2605","article-title":"Emergence of a novel swine-origin influenza A (H1N1) virus in humans","volume":"360","author":"FS Dawood","year":"2009"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1029\/2009JC005596","article-title":"Physical controls on the seasonal migration of the North Pacific transition zone chlorophyll front","volume":"115","author":"JM Ayers","year":"2010","journal-title":"J Geophys Res-Oceans"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/S0079-6611(01)00036-2","article-title":"The transition zone chlorophyll front, a dynamic global feature defining migration and forage habitat for marine resources","volume":"49","author":"JJ Polovina","year":"2001","journal-title":"Prog Oceanogr"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"2314","DOI":"10.1128\/JCM.00325-10","article-title":"Frequent Detection of Pandemic (H1N1) 2009 Virus in Stools of Hospitalized Patients","volume":"48","author":"SJ Yoo","year":"2010","journal-title":"J Clin Microbiol"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1139\/m80-108","article-title":"The perpetuation of orthomyxoviruses and paramyxoviruses in Canadian waterfowl","volume":"26","author":"VS Hinshaw","year":"1980","journal-title":"Can J Microbiol"},{"key":"ref31","first-page":"711","article-title":"Circulation of influenza viruses and paramyxoviruses in waterfowl originating from two different areas of North America","volume":"63","author":"VS Hinshaw","year":"1985","journal-title":"Bull World Health Organ"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1016\/0042-6822(81)90200-2","article-title":"Characterization of an influenza A virus from seals","volume":"113","author":"RG Webster","year":"1981","journal-title":"Virol"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/j.chom.2009.04.006","article-title":"Influenza A Virus NS1 Targets the Ubiquitin Ligase TRIM25 to Evade Recognition by the Host Viral RNA Sensor RIG-I","volume":"5","author":"MU Gack","year":"2009","journal-title":"Cell Host Microbe"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"958","DOI":"10.4161\/cc.9.5.10913","article-title":"Genomic analysis of pandemic (H1N1) 2009 reveals association of increasing disease severity with emergence of novel hemagglutinin","volume":"9","author":"GV Glinsky","year":"2010","journal-title":"Cell Cycle"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"RRN1162","DOI":"10.1371\/currents.RRN1162","article-title":"A new common mutation in the hemagglutinin of the 2009 (H1N1) influenza A virus","volume":"2","author":"S Maurer-Stroh","year":"2010","journal-title":"PLoS Curr"},{"key":"ref36","first-page":"1","article-title":"Evolution of the haemagglutinin gene of the influenza A (H1N1) 2009 virus isolated in Hong Kong, 2009\u20132011","volume":"16","author":"GC Mak","year":"2011","journal-title":"Euro Surveill"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"1757","DOI":"10.3201\/eid1709.101916","article-title":"Pandemic (H1N1) 2009 Virus in Swine Herds, People\u2019s Republic of China","volume":"17","author":"H Zhou","year":"2011","journal-title":"Emerg Infect Diseases"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"2107","DOI":"10.1016\/j.meegid.2011.05.002","article-title":"Influenza A\/H1N1 pdm virus in Russian Asia in 2009\u20132010","volume":"11","author":"T Ilyicheva","year":"2011","journal-title":"Infect Genet Evol"},{"key":"ref39","unstructured":"USAFSAM (2009) DoD Global, Lab-Based Influenza Surveillance Program, Week 9 Report 311 HSW\/PA No.09\u2013119."},{"key":"ref40","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1089\/vim.2010.0088","article-title":"Antibody-Binding Epitope Differences in the Nucleoprotein of Avian and Mammalian Influenza A Viruses","volume":"24","author":"NL Varich","year":"2011","journal-title":"Viral Immunol"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1007\/s11262-011-0571-2","article-title":"Comparison of two H1N2 swine influenza A viruses from disease outbreaks in pigs in Sweden during 2009 and 2010","volume":"42","author":"G Metreveli","year":"2011","journal-title":"Virus Genes"},{"key":"ref42","unstructured":"Tizard I (2000) Veterinary Immunology: An Introduction, 6th ed. Philadelphia, PA: Saunders. 180\u2013190."},{"key":"ref43","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0378-1135(00)00369-2","article-title":"Humoral immune responses to phocine herpesvirus-1 in Pacific harbor seals (<italic>Phoca vitulina richardsii<\/italic>) during an outbreak of clinical disease","volume":"80","author":"DP King","year":"2001","journal-title":"Vet Microbiol"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.vetmic.2004.06.017","article-title":"The transmission of phocine herpesvirus-1 in rehabilitating and free ranging Pacific harbor seals (<italic>Phoca vitulina<\/italic>) in California","volume":"103","author":"T Goldstein","year":"2004","journal-title":"Vet Microbiol"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0062259","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,26]],"date-time":"2020-07-26T20:15:33Z","timestamp":1595794533000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0062259"}},"subtitle":[],"editor":[{"given":"Ian C.","family":"Davis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2013,5,15]]},"references-count":44,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2013,5,15]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0062259","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,5,15]]}}}