{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T15:20:10Z","timestamp":1791300010332,"version":"4.1.0"},"reference-count":74,"publisher":"Public Library of Science (PLoS)","issue":"5","license":[{"start":{"date-parts":[[2013,5,7]],"date-time":"2013-05-07T00:00:00Z","timestamp":1367884800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0063218","type":"journal-article","created":{"date-parts":[[2013,5,8]],"date-time":"2013-05-08T00:40:59Z","timestamp":1367973659000},"page":"e63218","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":48,"title":["Distinct Functional and Temporal Requirements for Zebrafish Hdac1 during Neural Crest-Derived Craniofacial and Peripheral Neuron Development"],"prefix":"10.1371","volume":"8","author":[{"given":"Myron S.","family":"Ignatius","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arife","family":"Unal Eroglu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Smitha","family":"Malireddy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Glen","family":"Gallagher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roopa M.","family":"Nambiar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul D.","family":"Henion","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2013,5,7]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","unstructured":"LeDouarin N, Kalcheim C (1999) The Neural Crest. Cambridge Univ. Press, New York.","DOI":"10.1017\/CBO9780511897948"},{"key":"ref2","doi-asserted-by":"crossref","unstructured":"Barembaum M, Bronner-Fraser M (2005) Early Steps in Neural Crest Specification. Semin. Cell Dev. Biol. 16, 642\u2013646.","DOI":"10.1016\/j.semcdb.2005.06.006"},{"key":"ref3","doi-asserted-by":"crossref","unstructured":"Cornell RA, Eisen JS (2005) Notch in the Pathway: The Roles of Notch Signaling in Neural Crest Development. Semin. Cell Dev. Biol. 16, 663\u2013672.","DOI":"10.1016\/j.semcdb.2005.06.009"},{"key":"ref4","doi-asserted-by":"crossref","unstructured":"Steventon B, Carmona-Fontaine C, Mayor R (2005) Genetic Network during Neural Crest Induction: From Cell Specification to Cell Survival. Semin. Cell Dev. Biol. 16, 647\u2013654.","DOI":"10.1016\/j.semcdb.2005.06.001"},{"key":"ref5","doi-asserted-by":"crossref","unstructured":"Kos R, Reedy MV, Johnson RL, Erickson CA (2001) The Winged-Helix Transcription Factor FoxD3 is Important for Establishing the Neural Crest Lineage and Repressing Melanogenesis in Avian Embryos. Development 128, 1467\u20131479.","DOI":"10.1242\/dev.128.8.1467"},{"key":"ref6","unstructured":"Lister JA, Cooper C, Nguyen K, Modrell M, Grant K, <etal>et al<\/etal>.. (2006) Zebrafish Foxd3 is Required for Development of a Subset of Neural Crest Derivatives. Dev. Biol. 290, 92\u2013104."},{"key":"ref7","doi-asserted-by":"crossref","unstructured":"Sasai N, Mizuseki K, Sasai Y (2001) Requirement of FoxD3-Class Signaling for Neural Crest Determination in Xenopus. Development 128, 2525\u20132536.","DOI":"10.1242\/dev.128.13.2525"},{"key":"ref8","unstructured":"Stewart RA, Arduini BL, Berghmans S, George RE, Kanki JP, <etal>et al<\/etal>.. (2006) Zebrafish <italic>foxd3<\/italic> is Selectively Required for Neural Crest Specification, Migration and Survival. Dev. Biol. 292, 174\u2013188."},{"key":"ref9","doi-asserted-by":"crossref","unstructured":"Barrallo-Gimeno A, Holzschuh J, Driever W, Knapik EW (2004) Neural Crest Survival and Differentiation in Zebrafish Depends on Mont blanc\/tfap2a Gene Function. Development 131, 1463\u20131477.","DOI":"10.1242\/dev.01033"},{"key":"ref10","doi-asserted-by":"crossref","unstructured":"Knight RD, Nair S, Nelson SS, Afshar A, Javidan Y, <etal>et al<\/etal>.. (2003) Lockjaw Encodes a Zebrafish tfap2a Required for Early Neural Crest Development. Development 130, 5755\u20135768.","DOI":"10.1242\/dev.00575"},{"key":"ref11","unstructured":"O&apos;Brien EK, d&apos;Alencon C, Bonde G, Li W, Schoenebeck J, <etal>et al<\/etal>.. (2004) Transcription Factor Ap-2alpha is Necessary for Development of Embryonic Melanophores, Autonomic Neurons and Pharyngeal Skeleton in Zebrafish. Dev. Biol. 265, 246\u2013261."},{"key":"ref12","doi-asserted-by":"crossref","unstructured":"del Barrio MG, Nieto MA (2002) Overexpression of Snail Family Members Highlights their Ability to Promote Chick Neural Crest Formation. Development 129, 1583\u20131593.","DOI":"10.1242\/dev.129.7.1583"},{"key":"ref13","doi-asserted-by":"crossref","unstructured":"Sefton M, Sanchez S, Nieto MA (1998) Conserved and Divergent Roles for Members of the Snail Family of Transcription Factors in the Chick and Mouse Embryo. Development 125, 3111\u20133121.","DOI":"10.1242\/dev.125.16.3111"},{"key":"ref14","doi-asserted-by":"crossref","unstructured":"Epstein DJ, Vekemans M, Gros P (1991) Splotch (Sp2H), a Mutation Affecting Development of the Mouse Neural Tube, shows a Deletion within the Paired Homeodomain of Pax-3. Cell 67, 767\u2013774.","DOI":"10.1016\/0092-8674(91)90071-6"},{"key":"ref15","doi-asserted-by":"crossref","unstructured":"Yan YL, Miller CT, Nissen RM, Singer A, Liu D, <etal>et al<\/etal>.. (2002) A Zebrafish sox9 Gene Required for Cartilage Morphogenesis. Development 129, 5065\u20135079.","DOI":"10.1242\/dev.129.21.5065"},{"key":"ref16","doi-asserted-by":"crossref","unstructured":"Yan YL, Willoughby J, Liu D, Crump JG, Wilson C, <etal>et al<\/etal>.. (2005) A Pair of Sox: Distinct and Overlapping Functions of Zebrafish sox9 Co-Orthologs in Craniofacial and Pectoral Fin Development. Development 132, 1069\u20131083.","DOI":"10.1242\/dev.01674"},{"key":"ref17","doi-asserted-by":"crossref","unstructured":"Dutton KA, Pauliny A, Lopes SS, Elworthy S, Carney TJ, <etal>et al<\/etal>.. (2001) Zebrafish Colourless Encodes sox10 and Specifies Non-Ectomesenchymal Neural Crest Fates. Development 128, 4113\u20134125.","DOI":"10.1242\/dev.128.21.4113"},{"key":"ref18","doi-asserted-by":"crossref","unstructured":"Kelsh RN, Eisen JS (2000) The Zebrafish Colourless Gene Regulates Development of Non-Ectomesenchymal Neural Crest Derivatives. Development 127, 515\u2013525.","DOI":"10.1242\/dev.127.3.515"},{"key":"ref19","doi-asserted-by":"crossref","unstructured":"Etchevers HC, Amiel J, Lyonnet S (2006) Molecular Bases of Human Neurocristopathies. Adv. Exp. Med. Biol. 589, 213\u2013234.","DOI":"10.1007\/978-0-387-46954-6_14"},{"key":"ref20","doi-asserted-by":"crossref","unstructured":"Strahl BD, Allis CD (2000) The Language of Covalent Histone Modifications. Nature 403, 41\u201345.","DOI":"10.1038\/47412"},{"key":"ref21","doi-asserted-by":"crossref","unstructured":"Turner BM (2007) Defining an Epigenetic Code. Nat. Cell Biol. 9, 2\u20136.","DOI":"10.1038\/ncb0107-2"},{"key":"ref22","doi-asserted-by":"crossref","unstructured":"Jenuwein T, Allis CD (2001) Translating the Histone Code. Science 293, 1074\u20131080.","DOI":"10.1126\/science.1063127"},{"key":"ref23","doi-asserted-by":"crossref","unstructured":"Richards EJ, Elgin SC (2002) Epigenetic Codes for Heterochromatin Formation and Silencing: Rounding Up the Usual Suspects. Cell 108, 489\u2013500.","DOI":"10.1016\/S0092-8674(02)00644-X"},{"key":"ref24","doi-asserted-by":"crossref","unstructured":"Spotswood HY, Turner BM (2002) An Increasingly Complex Code. J. Clin. Invest. 110, 577\u2013582.","DOI":"10.1172\/JCI0216547"},{"key":"ref25","unstructured":"Allfrey VG (1966) Control Mechanisms in Ribonucleic Acid Synthesis. Cancer Res. 26, 2026\u20132040."},{"key":"ref26","doi-asserted-by":"crossref","unstructured":"Ahringer J (2000) NuRD and SIN3 Histone Deacetylase Complexes in Development. Trends Genet. 16, 351\u2013356.","DOI":"10.1016\/S0168-9525(00)02066-7"},{"key":"ref27","doi-asserted-by":"crossref","unstructured":"de Ruijter AJ, van Gennip AH, Caron HN, Kemp S, van Kuilenburg AB (2003) Histone Deacetylases (HDACs): Characterization of the Classical HDAC Family. Biochem. J. 370, 737\u2013749.","DOI":"10.1042\/bj20021321"},{"key":"ref28","doi-asserted-by":"crossref","unstructured":"Marks PA, Miller T, Richon VM (2003) Histone Deacetylases. Curr. Opin. Pharmacol. 3, 344\u2013351.","DOI":"10.1016\/S1471-4892(03)00084-5"},{"key":"ref29","doi-asserted-by":"crossref","unstructured":"Roth SY, Denu JM, Allis CD (2001) Histone Acetyltransferases. Annu. Rev. Biochem. 70, 81\u2013120.","DOI":"10.1146\/annurev.biochem.70.1.81"},{"key":"ref30","doi-asserted-by":"crossref","unstructured":"Dokmanovic M, Clarke C, Marks PA (2007) Histone Deacetylase Inhibitors: Overview and Perspectives. Mol. Cancer. Res. 5, 981\u2013989.","DOI":"10.1158\/1541-7786.MCR-07-0324"},{"key":"ref31","doi-asserted-by":"crossref","unstructured":"Cunliffe VT (2004) Histone Deacetylase 1 is Required to Repress Notch Target Gene Expression during Zebrafish Neurogenesis and to Maintain the Production of Motoneurones in Response to Hedgehog Signalling. Development 131, 2983\u20132995.","DOI":"10.1242\/dev.01166"},{"key":"ref32","doi-asserted-by":"crossref","unstructured":"Ignatius MS, Moose HE, El-Hodiri HM, Henion PD (2008) Colgate\/hdac1 Repression of foxd3 Expression is Required to Permit Mitfa-Dependent Melanogenesis. Dev. Biol. 313, 568\u2013583.","DOI":"10.1016\/j.ydbio.2007.10.045"},{"key":"ref33","doi-asserted-by":"crossref","unstructured":"Nambiar RM, Henion PD (2004) Sequential Antagonism of Early and Late Wnt-Signaling by Zebrafish Colgate Promotes Dorsal and Anterior Fates. Dev. Biol. 267, 165\u2013180.","DOI":"10.1016\/j.ydbio.2003.11.019"},{"key":"ref34","unstructured":"Stadler JA, Shkumatava A, Norton WH, Rau MJ, Geisler R, <etal>et al<\/etal>.. (2005) Histone Deacetylase 1 is Required for Cell Cycle Exit and Differentiation in the Zebrafish Retina. Dev. Dyn. 233, 883\u2013889."},{"key":"ref35","doi-asserted-by":"crossref","unstructured":"Yamaguchi M, Tonou-Fujimori N, Komori A, Maeda R, Nojima Y, <etal>et al<\/etal>.. (2005) Histone Deacetylase 1 Regulates Retinal Neurogenesis in Zebrafish by Suppressing Wnt and Notch Signaling Pathways. Development 132, 3027\u20133043.","DOI":"10.1242\/dev.01881"},{"key":"ref36","doi-asserted-by":"crossref","unstructured":"Nambiar RM, Ignatius MS, Henion PD (2007) Zebrafish colgate\/hdac1 Functions in the Non-Canonical Wnt Pathway during Axial Extension and in Wnt-Independent Branchiomotor Neuron Migration. Mech. Dev. 124, 682\u2013698.","DOI":"10.1016\/j.mod.2007.07.003"},{"key":"ref37","doi-asserted-by":"crossref","unstructured":"Pillai R, Coverdale LE, Dubey G, Martin CC (2004) Histone Deacetylase 1 (HDAC-1) Required for the Normal Formation of Craniofacial Cartilage and Pectoral Fins of the Zebrafish. Dev. Dyn. 231, 647\u2013654.","DOI":"10.1002\/dvdy.20168"},{"key":"ref38","doi-asserted-by":"crossref","unstructured":"Lagger G, O&apos;Carroll D, Rembold M, Khier H, Tischler J, <etal>et al<\/etal>.. (2002) Essential Function of Histone Deacetylase 1 in Proliferation Control and CDK Inhibitor Repression. EMBO J. 21, 2672\u20132681.","DOI":"10.1093\/emboj\/21.11.2672"},{"key":"ref39","doi-asserted-by":"crossref","unstructured":"Montgomery RL, Davis CA, Potthoff MJ, Haberland M, Fielitz J, <etal>et al<\/etal>.. (2007) Histone Deacetylases 1 and 2 Redundantly Regulate Cardiac Morphogenesis, Growth, and Contractility. Genes Dev. 21, 1790\u20131802.","DOI":"10.1101\/gad.1563807"},{"key":"ref40","doi-asserted-by":"crossref","unstructured":"Minucci S, Pelicci PG (2006) Histone Deacetylase Inhibitors and the Promise of Epigenetic (and More) Treatments for Cancer. Nat. Rev. Cancer. 6, 38\u201351.","DOI":"10.1038\/nrc1779"},{"key":"ref41","doi-asserted-by":"crossref","unstructured":"Xu WS, Parmigiani RB, Marks PA (2007) Histone Deacetylase Inhibitors: Molecular Mechanisms of Action. Oncogene 26, 5541\u20135552.","DOI":"10.1038\/sj.onc.1210620"},{"key":"ref42","doi-asserted-by":"crossref","unstructured":"Kimmel CB, Ballard WW, Kimmel SR, Ullmann B, Schilling TF (1995) Stages of Embryonic Development of the Zebrafish. Dev. Dyn. 203, 253\u2013310.","DOI":"10.1002\/aja.1002030302"},{"key":"ref43","doi-asserted-by":"crossref","unstructured":"Knapik EW, Goodman A, Atkinson OS, Roberts CT, Shiozawa M, <etal>et al<\/etal>.. (1996) A Reference Cross DNA Panel for Zebrafish (Danio Rerio) Anchored with Simple Sequence Length Polymorphisms. Development 123, 451\u2013460.","DOI":"10.1242\/dev.123.1.451"},{"key":"ref44","unstructured":"Knapik EW, Goodman A, Ekker M, Chevrette M, Delgado J, <etal>et al<\/etal>.. (1998) A Microsatellite Genetic Linkage Map for Zebrafish (Danio Rerio). Nat. Genet. 18, 338\u2013343."},{"key":"ref45","doi-asserted-by":"crossref","unstructured":"Schilling TF, Kimmel CB (1994) Segment and Cell Type Lineage Restrictions during Pharyngeal Arch Development in the Zebrafish Embryo. Development 120, 483\u2013494.","DOI":"10.1242\/dev.120.3.483"},{"key":"ref46","doi-asserted-by":"crossref","unstructured":"Thisse C, Thisse B, Schilling TF, Postlethwait JH (1993) Structure of the Zebrafish <italic>snail1<\/italic> Gene and its Expression in Wild-Type, Spadetail and no Tail Mutant Embryos. Development 119, 1203\u20131215.","DOI":"10.1242\/dev.119.4.1203"},{"key":"ref47","doi-asserted-by":"crossref","unstructured":"Luo R, An M, Arduini BL, Henion PD (2001) Specific Pan-Neural Crest Expression of Zebrafish Crestin Throughout Embryonic Development. Dev. Dyn. 220, 169\u2013174.","DOI":"10.1002\/1097-0177(2000)9999:9999<::AID-DVDY1097>3.0.CO;2-1"},{"key":"ref48","doi-asserted-by":"crossref","unstructured":"Rubinstein AL, Lee D, Luo R, Henion PD, Halpern ME (2000) Genes Dependent on Zebrafish Cyclops Function Identified by AFLP Differential Gene Expression Screen. Genesis 26, 86\u201397.","DOI":"10.1002\/(SICI)1526-968X(200001)26:1<86::AID-GENE11>3.0.CO;2-Q"},{"key":"ref49","doi-asserted-by":"crossref","unstructured":"Yan YL, Hatta K, Riggleman B, Postlethwait JH (1995) Expression of a Type II Collagen Gene in the Zebrafish Embryonic Axis. Dev. Dyn. 203, 363\u2013376.","DOI":"10.1002\/aja.1002030308"},{"key":"ref50","doi-asserted-by":"crossref","unstructured":"Holzschuh J, Barrallo-Gimeno A, Ettl AK, Durr K, Knapik EW, <etal>et al<\/etal>.. (2003) Noradrenergic Neurons in the Zebrafish Hindbrain are Induced by Retinoic Acid and Require tfap2a for Expression of the Neurotransmitter Phenotype. Development 130, 5741\u20135754.","DOI":"10.1242\/dev.00816"},{"key":"ref51","doi-asserted-by":"crossref","unstructured":"Akimenko MA, Ekker M, Wegner J, Lin W, Westerfield M (1994) Combinatorial Expression of Three Zebrafish Genes Related to Distal-Less: Part of a Homeobox Gene Code for the Head. J. Neurosci. 14, 3475\u20133486.","DOI":"10.1523\/JNEUROSCI.14-06-03475.1994"},{"key":"ref52","doi-asserted-by":"crossref","unstructured":"Yelon D, Ticho B, Halpern ME, Ruvinsky I, Ho RK, <etal>et al<\/etal>.. (2000) The bHLH Transcription Factor hand2 Plays Parallel Roles in Zebrafish Heart and Pectoral Fin Development. Development 127, 2573\u20132582.","DOI":"10.1242\/dev.127.12.2573"},{"key":"ref53","doi-asserted-by":"crossref","unstructured":"Hunter MP, Prince VE (2002) Zebrafish Hox Paralogue Group 2 Genes Function Redundantly as Selector Genes to Pattern the Second Pharyngeal Arch. Dev. Biol. 247, 367\u2013389.","DOI":"10.1006\/dbio.2002.0701"},{"key":"ref54","doi-asserted-by":"crossref","unstructured":"Guo S, Brush J, Teraoka H, Goddard A, Wilson SW, <etal>et al<\/etal>.. (1999) Development of Noradrenergic Neurons in the Zebrafish Hindbrain Requires BMP, FGF8, and the Homeodomain Protein soulless\/Phox2a. Neuron 24, 555\u2013566.","DOI":"10.1016\/S0896-6273(00)81112-5"},{"key":"ref55","doi-asserted-by":"crossref","unstructured":"Piotrowski T, Ahn DG, Schilling TF, Nair S, Ruvinsky I, <etal>et al<\/etal>.. (2003) The Zebrafish Van Gogh Mutation Disrupts tbx1, which is Involved in the DiGeorge Deletion Syndrome in Humans. Development 130, 5043\u20135052.","DOI":"10.1242\/dev.00704"},{"key":"ref56","doi-asserted-by":"crossref","unstructured":"Stewart RA, Look AT, Kanki JP, Henion PD (2004) Development of the Peripheral Sympathetic Nervous System in Zebrafish. Methods Cell Biol. 76, 237\u2013260.","DOI":"10.1016\/S0091-679X(04)76012-4"},{"key":"ref57","doi-asserted-by":"crossref","unstructured":"Knight RD, Schilling TF (2006) CRANIAL NEURAL CREST AND DEVELOPMENT OF THE HEAD SKELETON. In Neural Crest Induction and Differentiation (ed. J. P. Saint-Jeannet), 120. USA: Landes Bioscience.","DOI":"10.1007\/978-0-387-46954-6_7"},{"key":"ref58","doi-asserted-by":"crossref","first-page":"7640","DOI":"10.1073\/pnas.88.17.7640","article-title":"Expression of a partially deleted gene of human type II procollagen (COL2A1) in transgenic mice produces a chondrodysplasia","volume":"88(17)","author":"P Vandenberg","year":"1991","journal-title":"Proc Natl Acad Sci USA"},{"key":"ref59","unstructured":"Bell DM, Leung KK, Wheatley SC, Ng LJ, Zhou S, <etal>et al<\/etal>.. (1997) SOX9 Directly Regulates the Type-II Collagen Gene. Nat. Genet. 16, 174\u2013178."},{"key":"ref60","doi-asserted-by":"crossref","unstructured":"Lefebvre V, Huang W, Harley VR, Goodfellow PN, de Crombrugghe B (1997) SOX9 is a Potent Activator of the Chondrocyte-Specific Enhancer of the Pro alpha1(II) Collagen Gene. Mol. Cell. Biol. 17, 2336\u20132346.","DOI":"10.1128\/MCB.17.4.2336"},{"key":"ref61","unstructured":"Ng LJ, Wheatley S, Muscat GE, Conway-Campbell J, Bowles J, <etal>et al<\/etal>.. (1997) SOX9 Binds DNA, Activates Transcription, and Coexpresses with Type II Collagen during Chondrogenesis in the Mouse. Dev. Biol. 183, 108\u2013121."},{"key":"ref62","unstructured":"Wright E, Hargrave MR, Christiansen J, Cooper L, Kun J, <etal>et al<\/etal>.. (1995) The Sry-Related Gene Sox9 is Expressed during Chondrogenesis in Mouse Embryos. Nat. Genet. 9, 15\u201320."},{"key":"ref63","doi-asserted-by":"crossref","unstructured":"Zhao Q, Eberspaecher H, Lefebvre V, De Crombrugghe B (1997) Parallel Expression of Sox9 and Col2a1 in Cells Undergoing Chondrogenesis. Dev. Dyn. 209, 377\u2013386.","DOI":"10.1002\/(SICI)1097-0177(199708)209:4<377::AID-AJA5>3.0.CO;2-F"},{"key":"ref64","doi-asserted-by":"crossref","unstructured":"An M, Luo R, Henion PD (2002) Differentiation and Maturation of Zebrafish Dorsal Root and Sympathetic Ganglion Neurons. J. Comp. Neurol. 446, 267\u2013275.","DOI":"10.1002\/cne.10214"},{"key":"ref65","doi-asserted-by":"crossref","unstructured":"Carney TJ, Dutton KA, Greenhill E, Delfino-Machin M, Dufourcq P, <etal>et al<\/etal>.. (2006) A Direct Role for Sox10 in Specification of Neural Crest-Derived Sensory Neurons. Development 133, 4619\u20134630.","DOI":"10.1242\/dev.02668"},{"key":"ref66","doi-asserted-by":"crossref","unstructured":"Britsch S, Goerich DE, Riethmacher D, Peirano RI, Rossner M, <etal>et al<\/etal>.. (2001) The transcription factor Sox10 is a key regulator of peripheral glial development. Genes Dev. 15, 66\u201378.","DOI":"10.1101\/gad.186601"},{"key":"ref67","unstructured":"Sonnenberg-Riethmacher E, Miehe M, Stolt CC, Goerich DE, Wegner M <etal>et al<\/etal>.. (2001) Development and degeneration of dorsal root ganglia in the absence of the HMG-domain transcription factor Sox10. Mech. Dev. 109, 253\u2013265."},{"key":"ref68","doi-asserted-by":"crossref","unstructured":"Howard MJ (2005) Mechanisms and Perspectives on Differentiation of Autonomic Neurons. Dev. Biol. 277, 271\u2013286.","DOI":"10.1016\/j.ydbio.2004.09.034"},{"key":"ref69","doi-asserted-by":"crossref","unstructured":"Huber K (2006) The Sympathoadrenal Cell Lineage: Specification, Diversification, and New Perspectives. Dev. Biol. 298, 335\u2013343.","DOI":"10.1016\/j.ydbio.2006.07.010"},{"key":"ref70","doi-asserted-by":"crossref","unstructured":"Lucas ME, Muller F, Rudiger R, Henion PD, Rohrer H (2006) The bHLH Transcription Factor hand2 is Essential for Noradrenergic Differentiation of Sympathetic Neurons. Development 133, 4015\u20134024.","DOI":"10.1242\/dev.02574"},{"key":"ref71","doi-asserted-by":"crossref","unstructured":"Haberland M, Montgomery, Olson EN (2009) The many roles of histone deacetylases in development and physiology: implications for disease and therapy. Nature Rev. Genetics, 10, 32\u201342.","DOI":"10.1038\/nrg2485"},{"key":"ref72","doi-asserted-by":"crossref","unstructured":"Minoux M, Rijli FM (2010) Molecular Mechanisms of Cranial Neural Crest Cell Migration and Patterning in Cranifacial Development. Development 137, 2605\u20132621.","DOI":"10.1242\/dev.040048"},{"key":"ref73","doi-asserted-by":"crossref","unstructured":"Medeiros DM, Crump JG (2012) New perspectives on pharyngeal dorsoventral patterning in development and evolution of the vertebrate jaw. Dev. Biol., <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/dx.doi.org\/10.1016\/j.ydbio.2012.08.026\" xlink:type=\"simple\">http:\/\/dx.doi.org\/10.1016\/j.ydbio.2012.08.026<\/ext-link>.","DOI":"10.1016\/j.ydbio.2012.08.026"},{"key":"ref74","doi-asserted-by":"crossref","unstructured":"Cunliffe VT, Casaccia-Bonnefil P (2006) Histone Deacetylase 1 is Essential for Oligodendrocyte Specification in the Zebrafish CNS. Mech. Dev. 123, 24\u201330.","DOI":"10.1016\/j.mod.2005.10.005"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0063218","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,16]],"date-time":"2022-02-16T11:33:34Z","timestamp":1645011214000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0063218"}},"subtitle":[],"editor":[{"given":"Henry H.","family":"Roehl","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2013,5,7]]},"references-count":74,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2013,5,7]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0063218","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,5,7]]}}}