{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T08:28:09Z","timestamp":1782289689592,"version":"3.54.5"},"reference-count":82,"publisher":"Public Library of Science (PLoS)","issue":"6","license":[{"start":{"date-parts":[[2013,6,18]],"date-time":"2013-06-18T00:00:00Z","timestamp":1371513600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0066549","type":"journal-article","created":{"date-parts":[[2013,6,18]],"date-time":"2013-06-18T23:36:24Z","timestamp":1371598584000},"page":"e66549","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":40,"title":["Mitigation of Lethal Radiation Syndrome in Mice by Intramuscular Injection of 3D Cultured Adherent Human Placental Stromal Cells"],"prefix":"10.1371","volume":"8","author":[{"given":"Elena","family":"Gaberman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lena","family":"Pinzur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lilia","family":"Levdansky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Tsirlin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nir","family":"Netzer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zami","family":"Aberman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raphael","family":"Gorodetsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2013,6,18]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"851","DOI":"10.3109\/09553002.2011.560996","article-title":"After the bomb drops: a new look at radiation-induced multiple organ dysfunction syndrome (MODS)","volume":"87","author":"JP Williams","year":"2011","journal-title":"Int J Radiat Biol"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/j.annemergmed.2005.01.020","article-title":"Medical treatment of radiological casualties: current concepts","volume":"45","author":"KL Koenig","year":"2005","journal-title":"Ann Emerg Med"},{"key":"ref3","doi-asserted-by":"crossref","unstructured":"Meineke V, Fliedner TM (2005) Radiation-induced multi-organ involvement and failure: challenges for radiation accident medical management and future research. BJR Suppl 27: 196\u2013200.","DOI":"10.1259\/bjr\/25654769"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"698","DOI":"10.7205\/MILMED.171.8.698","article-title":"Strategic National Stockpile program: implications for military medicine","volume":"171","author":"JT Need","year":"2006","journal-title":"Mil Med"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1093\/rpd\/ncn173","article-title":"Estimation of health hazards resulting from a radiological terrorist attack in a city","volume":"131","author":"KG Andersson","year":"2008","journal-title":"Radiat Prot Dosimetry"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"117","DOI":"10.4103\/0974-2700.50747","article-title":"Health implications of radiological terrorism: Perspectives from Israel","volume":"2","author":"M Hagby","year":"2009","journal-title":"J Emerg Trauma Shock"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"1945","DOI":"10.1089\/ars.2010.3742","article-title":"Radiation as a risk factor for cardiovascular disease","volume":"15","author":"JE Baker","year":"2011","journal-title":"Antioxid Redox Signal"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1097\/SMJ.0b013e3181ddd571","article-title":"Acute radiation syndrome: assessment and management","volume":"103","author":"EH Donnelly","year":"2010","journal-title":"South Med J"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"S94","DOI":"10.1016\/j.ijrobp.2009.06.092","article-title":"Radiation-associated liver injury","volume":"76","author":"CC Pan","year":"2010","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"S108","DOI":"10.1016\/j.ijrobp.2009.02.089","article-title":"Radiation-associated kidney injury","volume":"76","author":"LA Dawson","year":"2010","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1097\/00004032-200305000-00001","article-title":"Dose response relationships for acute ionizing-radiation lethality","volume":"84","author":"GH Anno","year":"2003","journal-title":"Health Phys"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"1913","DOI":"10.1016\/0360-3016(83)90362-0","article-title":"Magna-field irradiation: physical considerations","volume":"9","author":"J Van Dyk","year":"1983","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.brainres.2009.12.001","article-title":"Transplantation of placenta-derived mesenchymal stromal cells upon experimental stroke in rats","volume":"1315","author":"A Kranz","year":"2010","journal-title":"Brain Res"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1532\/IJH97.05046","article-title":"Influence of radiation dose rate and lung dose on interstitial pneumonitis after fractionated total body irradiation: acute parotitis may predict interstitial pneumonitis","volume":"83","author":"N Oya","year":"2006","journal-title":"Int J Hematol"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1667\/RR1880.1","article-title":"Animal models for medical countermeasures to radiation exposure","volume":"173","author":"JP Williams","year":"2010","journal-title":"Radiat Res"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1667\/RR1824.1","article-title":"Gamma-tocotrienol protects hematopoietic stem and progenitor cells in mice after total-body irradiation","volume":"173","author":"S Kulkarni","year":"2010","journal-title":"Radiat Res"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1080\/10715760701689550","article-title":"Low molecular weight catalytic metalloporphyrin antioxidant AEOL 10150 protects lungs from fractionated radiation","volume":"41","author":"ZN Rabbani","year":"2007","journal-title":"Free Radic Res"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"e30434","DOI":"10.1371\/journal.pone.0030434","article-title":"HemaMax, a recombinant human interleukin-12, is a potent mitigator of acute radiation injury in mice and non-human primates","volume":"7","author":"LA Basile","year":"2012","journal-title":"PLoS One"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1182\/blood.V92.3.765","article-title":"FLT-3 ligand provides hematopoietic protection from total body irradiation in rabbits","volume":"92","author":"A Gratwohl","year":"1998","journal-title":"Blood"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1089\/scd.2004.13.548","article-title":"Maintenance and self-renewal of long-term reconstituting hematopoietic stem cells supported by amniotic fluid","volume":"13","author":"E Barria","year":"2004","journal-title":"Stem Cells Dev"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"4084","DOI":"10.1200\/JCO.2007.11.5816","article-title":"Pharmacologic approaches to radiation protection","volume":"25","author":"DM Brizel","year":"2007","journal-title":"J Clin Oncol"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"215","DOI":"10.2307\/3575250","article-title":"Survival of bone marrow-engrafted mice subsequent to protection from lethal radiation by WR 2721","volume":"82","author":"KE Kinnamon","year":"1980","journal-title":"Radiat Res"},{"key":"ref23","first-page":"349","article-title":"Radioprotective and hemodynamic effects of WR-2721 and cystamine in rats: time course studies","volume":"30","author":"P Kuna","year":"1983","journal-title":"Neoplasma"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"319","DOI":"10.3109\/02841868209134022","article-title":"Toxicity and radiation protective effect of WR-77913 in BALB\/c mice","volume":"21","author":"OA Mendiondo","year":"1982","journal-title":"Acta Radiol Oncol"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1016\/0360-3016(76)90152-8","article-title":"Protection of normal tissues by WR2721 during fractionated irradiation","volume":"1","author":"JF Utley","year":"1976","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1053\/srao.2003.50006","article-title":"Chemical radioprotection: a critical review of amifostine as a cytoprotector in radiotherapy","volume":"13","author":"CN Andreassen","year":"2003","journal-title":"Semin Radiat Oncol"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1126\/scitranslmed.3003126","article-title":"Bactericidal\/permeability-increasing protein (rBPI21) and fluoroquinolone mitigate radiation-induced bone marrow aplasia and death","volume":"3","author":"EC Guinan","year":"2011","journal-title":"Sci Transl Med"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"1436","DOI":"10.1016\/j.ijrobp.2007.12.009","article-title":"Impact of drug therapy, radiation dose, and dose rate on renal toxicity following bone marrow transplantation","volume":"71","author":"JC Cheng","year":"2008","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"ref29","first-page":"168","article-title":"Need, feasibility and convenience of dosimetric treatment planning in liver selective internal radiation therapy with (90)Y microspheres: the experience of the National Tumor Institute of Milan","volume":"55","author":"C Chiesa","year":"2011","journal-title":"Q J Nucl Med Mol Imaging"},{"key":"ref30","first-page":"375","article-title":"Immunosuppressive Properties of Mesenchymal Stem Cells","volume":"2","author":"M Abumaree","year":"2011","journal-title":"Stem Cell Rev"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1159\/000128968","article-title":"Immune Modulation by Mesenchymal Stem Cells","volume":"35","author":"F Bifari","year":"2008","journal-title":"Transfus Med Hemother"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"3499","DOI":"10.1182\/blood-2007-02-069716","article-title":"Immunomodulatory properties of mesenchymal stromal cells","volume":"110","author":"AJ Nauta","year":"2007","journal-title":"Blood"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1080\/14653240601045399","article-title":"Mesenchymal stromal cells: Tissue repair and immune modulation","volume":"8","author":"K Le Blanc","year":"2006","journal-title":"Cytotherapy"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"385","DOI":"10.3892\/ijo.2010.869","article-title":"Mesenchymal stem cell-mediated T cell suppression occurs through secreted galectins","volume":"38","author":"M Sioud","year":"2011","journal-title":"Int J Oncol"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1186\/scrt34","article-title":"New concepts on the immune modulation mediated by mesenchymal stem cells","volume":"1","author":"BA Bunnell","year":"2010","journal-title":"Stem Cell Res Ther"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"268","DOI":"10.3341\/kjo.2011.25.4.268","article-title":"Modulation of retinal wound healing by systemically administered bone marrow-derived mesenchymal stem cells","volume":"25","author":"JK Chung","year":"2011","journal-title":"Korean J Ophthalmol"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"1963","DOI":"10.1002\/jcb.23119","article-title":"Allogeneic mesenchymal stem cells: agents of immune modulation","volume":"112","author":"K English","year":"2011","journal-title":"J Cell Biochem"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"697","DOI":"10.2119\/molmed.2010.00098","article-title":"Interleukin (IL)-10 induced by CD11b(+) cells and IL-10-activated regulatory T cells play a role in immune modulation of mesenchymal stem cells in rat islet allografts","volume":"17","author":"YH Kim","year":"2011","journal-title":"Mol Med"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1007\/978-3-642-82218-6_6","article-title":"Management of small cell cancer: radiotherapy","volume":"92","author":"NM Bleehen","year":"1984","journal-title":"Recent Results Cancer Res"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.ydbio.2011.10.022","article-title":"Modulation of Bmp4 signalling in the epithelial-mesenchymal interactions that take place in early thymus and parathyroid development in avian embryos","volume":"361","author":"H Neves","year":"2011","journal-title":"Dev Biol"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1002\/jbm.a.33121","article-title":"Modulation of immunological properties of allogeneic mesenchymal stem cells by collagen scaffolds in cartilage tissue engineering","volume":"98","author":"T Yuan","year":"2011","journal-title":"J Biomed Mater Res A"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1038\/sj.clpt.6100313","article-title":"\u201cStemness\u201d does not explain the repair of many tissues by mesenchymal stem\/multipotent stromal cells (MSCs)","volume":"82","author":"DJ Prockop","year":"2007","journal-title":"Clin Pharmacol Ther"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1016\/0360-3016(90)90443-N","article-title":"Radiation effect in mouse skin: dose fractionation and wound healing","volume":"18","author":"R Gorodetsky","year":"1990","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"ref44","doi-asserted-by":"crossref","unstructured":"Krueger WW, Goepfert H, Romsdahl M, Herson J, Withers RH, <etal>et al<\/etal>.. (1978) Fibroblast implantation enhances wound healing as indicated by breaking strength determinations. Otolaryngology 86: ORL 804\u201311.","DOI":"10.1177\/019459987808600527"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1159\/000147276","article-title":"MSC - a Multipotent Stromal Cell in Search of Clinical Application","volume":"35","author":"T Tonn","year":"2008","journal-title":"Transfus Med Hemother"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"267","DOI":"10.3109\/14653249.2011.616194","article-title":"Mesenchymal stromal cell-conditioned medium prevents radiation-induced small intestine injury in mice","volume":"14","author":"Z Gao","year":"2011","journal-title":"Cytotherapy"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"e24072","DOI":"10.1371\/journal.pone.0024072","article-title":"Bone marrow stromal cell transplantation mitigates radiation-induced gastrointestinal syndrome in mice","volume":"6","author":"S Saha","year":"2011","journal-title":"PLoS One"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.stem.2009.05.003","article-title":"Intravenous hMSCs improve myocardial infarction in mice because cells embolized in lung are activated to secrete the anti-inflammatory protein TSG-6","volume":"5","author":"RH Lee","year":"2009","journal-title":"Cell Stem Cell"},{"key":"ref49","doi-asserted-by":"crossref","unstructured":"Thierry D, Bertho JM, Chapel A, Gourmelon P (2005) Cell therapy for the treatment of accidental radiation overexposure. BJR Suppl 27: 175\u2013179.","DOI":"10.1259\/bjr\/90209767"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1259\/bjr\/61042310","article-title":"The radiation protection and therapy effects of mesenchymal stem cells in mice with acute radiation injury","volume":"83","author":"KX Hu","year":"2010","journal-title":"Br J Radiol"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1634\/stemcells.2007-0594","article-title":"Concise review: isolation and characterization of cells from human term placenta: outcome of the first international Workshop on Placenta Derived Stem Cells","volume":"26","author":"O Parolini","year":"2008","journal-title":"Stem Cells"},{"key":"ref52","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1080\/14653240902849762","article-title":"The role of placental-derived adherent stromal cell (PLX-PAD) in the treatment of critical limb ischemia","volume":"11","author":"WR Prather","year":"2009","journal-title":"Cytotherapy"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1517\/14712598.8.8.1241","article-title":"Placental-derived and expanded mesenchymal stromal cells (PLX-I) to enhance the engraftment of hematopoietic stem cells derived from umbilical cord blood","volume":"8","author":"WR Prather","year":"2008","journal-title":"Expert Opin Biol Ther"},{"key":"ref54","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1007\/s10529-009-0110-6","article-title":"Migratory response of mesenchymal stem cells to macrophage migration inhibitory factor and its antagonist as a function of colony-forming efficiency","volume":"32","author":"BW Fischer-Valuck","year":"2010","journal-title":"Biotechnol Lett"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/S0091-679X(01)63021-8","article-title":"Flow cytometric analysis of cell division history using dilution of carboxyfluorescein diacetate succinimidyl ester, a stably integrated fluorescent probe","volume":"63","author":"AB Lyons","year":"2001","journal-title":"Methods Cell Biol"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"e14486","DOI":"10.1371\/journal.pone.0014486","article-title":"Radiation rescue: mesenchymal stromal cells protect from lethal irradiation","volume":"6","author":"C Lange","year":"2011","journal-title":"PLoS One"},{"key":"ref57","doi-asserted-by":"crossref","first-page":"142530","DOI":"10.1155\/2012\/142530","article-title":"Marrow Stromal Cell Infusion Rescues Hematopoiesis in Lethally Irradiated Mice despite Rapid Clearance after Infusion","volume":"2012","author":"X Yang","year":"2012","journal-title":"Adv Hematol"},{"key":"ref58","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1016\/j.exphem.2013.01.002","article-title":"Mitigating effects of hUCB-MSCs on the hematopoietic syndrome resulting from total body irradiation","volume":"41","author":"S Shim","year":"2013","journal-title":"Exp Hematol"},{"key":"ref59","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1667\/RR2894.1","article-title":"Myeloid Progenitors: A Radiation Countermeasure that is Effective when Initiated Days after Irradiation","volume":"177","author":"VK Singh","year":"2012","journal-title":"Radiat Res"},{"key":"ref60","doi-asserted-by":"crossref","first-page":"2335","DOI":"10.1089\/ten.tea.2008.0434","article-title":"Small-molecule antagonist of macrophage migration inhibitory factor enhances migratory response of mesenchymal stem cells to bronchial epithelial cells","volume":"15","author":"BL Barrilleaux","year":"2009","journal-title":"Tissue Eng Part A"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1080\/09553000310001600907","article-title":"Time factor for acute tissue reactions following fractionated irradiation: a balance between repopulation and enhanced radiosensitivity","volume":"79","author":"JW Hopewell","year":"2003","journal-title":"Int J Radiat Biol"},{"key":"ref62","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.exphem.2007.01.011","article-title":"Whole-body responses to low-level radiation exposure: new concepts in mammalian radiobiology","volume":"35","author":"LE Feinendegen","year":"2007","journal-title":"Exp Hematol"},{"key":"ref63","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1259\/bjr.70.840.9505837","article-title":"The radiobiological basis of total body irradiation","volume":"70","author":"TE Wheldon","year":"1997","journal-title":"Br J Radiol"},{"key":"ref64","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1088\/0031-9155\/29\/7\/014","article-title":"The shape of the dose-response curve and the saturation of the Elkind repair","volume":"29","author":"M Bistrovic","year":"1984","journal-title":"Phys Med Biol"},{"key":"ref65","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/S0006-3495(70)86296-8","article-title":"Two forms of repair of DNA in mammalian cells following irradiation","volume":"10","author":"MM Elkind","year":"1970","journal-title":"Biophys J"},{"key":"ref66","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/0360-3016(83)90215-8","article-title":"Repair of potentially lethal X ray damage and possible applications to clinical radiotherapy","volume":"9","author":"RR Weichselbaum","year":"1983","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"ref67","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.1016\/0360-3016(81)90195-4","article-title":"Radiobiological basis of total body irradiation with different dose rate and fractionation: repair capacity of hemopoietic cells","volume":"7","author":"CW Song","year":"1981","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"ref68","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1111\/j.1749-6632.1964.tb53566.x","article-title":"Repair Processes in Irradiated Mouse Hematopoietic Tissue","volume":"114","author":"JE Till","year":"1964","journal-title":"Ann N Y Acad Sci"},{"key":"ref69","first-page":"221","article-title":"Normal tissue radiosensitivity: prediction on deterministic or stochastic basis?","volume":"17","author":"HK Awwad","year":"2005","journal-title":"J Egypt Natl Canc Inst"},{"key":"ref70","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1006\/cyto.1996.0095","article-title":"Effects of interleukin 6 administration on platelets and haemopoietic progenitor cells in peripheral blood","volume":"8","author":"D Clarke","year":"1996","journal-title":"Cytokine"},{"key":"ref71","doi-asserted-by":"crossref","first-page":"1927","DOI":"10.1002\/eji.1830200909","article-title":"Interleukin 6 is a differentiation factor for human megakaryocytes in vitro","volume":"20","author":"H Kimura","year":"1990","journal-title":"Eur J Immunol"},{"key":"ref72","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1038\/nature02041","article-title":"Identification of the haematopoietic stem cell niche and control of the niche size","volume":"425","author":"J Zhang","year":"2003","journal-title":"Nature"},{"key":"ref73","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/S0962-8924(99)01559-7","article-title":"Homing and mobilization in the stem cell niche","volume":"9","author":"AD Whetton","year":"1999","journal-title":"Trends Cell Biol"},{"key":"ref74","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1159\/000203664","article-title":"Peripheral blood mobilization of hematopoietic stem cells: cytokine-mediated regulation of adhesive interactions within the hematopoietic microenvironment","volume":"97","author":"MA Santucci","year":"1997","journal-title":"Acta Haematol"},{"key":"ref75","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1002\/stem.5530120306","article-title":"A quantitative assay that evaluates the capacity of human stromal cells to support granulomonopoiesis in situ","volume":"12","author":"E Tamayo","year":"1994","journal-title":"Stem Cells"},{"key":"ref76","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/j.ceb.2009.05.004","article-title":"Adhesion within the stem cell niches","volume":"21","author":"K Raymond","year":"2009","journal-title":"Curr Opin Cell Biol"},{"key":"ref77","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.1016\/j.biomaterials.2011.11.034","article-title":"3D co-culture of hematopoietic stem and progenitor cells and mesenchymal stem cells in collagen scaffolds as a model of the hematopoietic niche","volume":"33","author":"I Leisten","year":"2012","journal-title":"Biomaterials"},{"key":"ref78","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1007\/s12185-011-1001-x","article-title":"Myelodysplastic syndromes: revisiting the role of the bone marrow microenvironment in disease pathogenesis","volume":"95","author":"MH Raaijmakers","year":"2012","journal-title":"Int J Hematol"},{"key":"ref79","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1007\/s11914-011-0075-y","article-title":"Stem cell interactions in a bone marrow niche","volume":"9","author":"J Isern","year":"2011","journal-title":"Curr Osteoporos Rep"},{"key":"ref80","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1111\/j.1749-6632.2009.04608.x","article-title":"Genetic models to study quiescent stem cells and their niches","volume":"1176","author":"C Schaniel","year":"2009","journal-title":"Ann N Y Acad Sci"},{"key":"ref81","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/j.cell.2007.08.025","article-title":"Self-renewing osteoprogenitors in bone marrow sinusoids can organize a hematopoietic microenvironment","volume":"131","author":"B Sacchetti","year":"2007","journal-title":"Cell"},{"key":"ref82","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.mvr.2012.02.011","article-title":"Paracrine effects of mesenchymal stem cells enhance vascular regeneration in ischemic murine skin","volume":"83","author":"S Schlosser","year":"2012","journal-title":"Microvasc Res"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0066549","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,28]],"date-time":"2020-07-28T18:39:30Z","timestamp":1595961570000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0066549"}},"subtitle":[],"editor":[{"given":"Marie Jose","family":"Goumans","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2013,6,18]]},"references-count":82,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2013,6,18]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0066549","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,6,18]]}}}