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Countermeasures Injury Compensation Program (CICP): Administrative Implementation, Interim Final Rule<\/italic>; Final Rule: U.S. Department of Health and Human Services. Available: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.gpo.gov\/fdsys\/pkg\/FR-2010-10-15\/pdf\/2010-25110.pdf\" xlink:type=\"simple\">http:\/\/www.gpo.gov\/fdsys\/pkg\/FR-2010-10-15\/pdf\/2010-25110.pdf<\/ext-link>. Accessed August 13, 2012."},{"key":"ref21","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.amepre.2011.04.004","article-title":"H1N1 and seasonal influenza vaccine safety in the Vaccine Safety Datalink Project","volume":"41","author":"GM Lee","year":"2011","journal-title":"Am J Prev Med"},{"key":"ref22","first-page":"423","article-title":"Update: influenza activity - United States, August 30, 2009-March 27, 2010, and composition of the 2010\u201311 influenza vaccine","volume":"59","year":"2010","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/S1473-3099(10)70140-7","article-title":"Guillain-Barr\u00e9 syndrome after exposure to influenza virus","volume":"10","author":"HC Lehmann","year":"2010","journal-title":"Lancet Infect Dis"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1007\/s11908-011-0194-8","article-title":"Guillain-Barr\u00e9 syndrome following influenza vaccination: causal or coincidental?","volume":"13","author":"JJ Sejvar","year":"2011","journal-title":"Curr Infect Dis Rep"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"5801","DOI":"10.1016\/j.vaccine.2012.06.093","article-title":"Influenza vaccine, Guillain-Barr\u00e9 syndrome, and chasing zero","volume":"30","author":"GA Poland","year":"2012","journal-title":"Vaccine"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"S45","DOI":"10.1542\/peds.2010-1722H","article-title":"The Vaccine Safety Datalink: a model for monitoring immunization safety","volume":"127","author":"J Baggs","year":"2011","journal-title":"Pediatrics"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1212\/01.wnl.0000167549.09664.b8","article-title":"Distinguishing acute-onset CIDP from Guillain-Barr\u00e9 syndrome with treatment related fluctuations","volume":"65","author":"L Ruts","year":"2005","journal-title":"Neurology"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/j.vaccine.2010.06.003","article-title":"Guillain-Barr\u00e9 syndrome and Fisher syndrome: Case definitions and guidelines for collection, analysis, and presentation of immunization safety data","volume":"29","author":"JJ Sejvar","year":"2011","journal-title":"Vaccine"},{"key":"ref29","article-title":"National Bioterrorism Syndromic Surveillance Demonstration Program","volume":"53","author":"WK Yih","year":"2004","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1542\/peds.2010-0665","article-title":"Measles-mumps-rubella-varicella combination vaccine and the risk of febrile seizures","volume":"126","author":"NP Klein","year":"2010","journal-title":"Pediatrics"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1093\/aje\/kws011","article-title":"Immunization and Bell\u2019s palsy in children: a case-centered analysis","volume":"175","author":"A Rowhani-Rahbar","year":"2012","journal-title":"Am J Epidemiol"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.vaccine.2011.10.104","article-title":"Lack of association between childhood immunizations and encephalitis in California, 1998\u20132008","volume":"30","author":"BA Pahud","year":"2012","journal-title":"Vaccine"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1093\/aje\/kwp173","article-title":"Influenza vaccination and mortality: differentiating vaccine effects from bias","volume":"170","author":"B Fireman","year":"2009","journal-title":"Am J Epidemiol"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1159\/000184748","article-title":"The epidemiology of Guillain-Barr\u00e9 syndrome worldwide. 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Washington, DC: National Academy Press."},{"key":"ref38","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1093\/oxfordjournals.aje.a009785","article-title":"Quality of HMO vaccination databases used to monitor childhood vaccine safety. 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