{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T19:43:00Z","timestamp":1790538180516,"version":"4.1.0"},"reference-count":36,"publisher":"Public Library of Science (PLoS)","issue":"7","license":[{"start":{"date-parts":[[2013,7,17]],"date-time":"2013-07-17T00:00:00Z","timestamp":1374019200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0068699","type":"journal-article","created":{"date-parts":[[2013,7,17]],"date-time":"2013-07-17T17:06:26Z","timestamp":1374080786000},"page":"e68699","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":81,"title":["Infections in Children Admitted with Complicated Severe Acute Malnutrition in Niger"],"prefix":"10.1371","volume":"8","author":[{"given":"Anne-Laure","family":"Page","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathalie","family":"de Rekeneire","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sani","family":"Sayadi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Said","family":"Aberrane","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann-Carole","family":"Janssens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Rieux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Djibo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Claude","family":"Manuguerra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hubert","family":"Ducou-le-Pointe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca F.","family":"Grais","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myrto","family":"Schaefer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe J.","family":"Guerin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuel","family":"Baron","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2013,7,17]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"e115","DOI":"10.1371\/journal.pmed.0040115","article-title":"Malnutrition and infection: complex mechanisms and global impacts","volume":"4","author":"UE Schaible","year":"2007","journal-title":"PLoS Med"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/S0140-6736(07)61690-0","article-title":"Maternal and child undernutrition: global and regional exposures and health consequences","volume":"371","author":"RE Black","year":"2008","journal-title":"Lancet"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1177\/153537020422900603","article-title":"Nutrition and infectious diseases in developing countries and problems of acquired immunodeficiency syndrome","volume":"229","author":"JL Ambrus Sr","year":"2004","journal-title":"Exp Biol Med (Maywood )"},{"key":"ref4","unstructured":"Ashworth A, Khanum S, Jackson A, Schofield C (2003) Guidelines for the inpatient treatment of severely malnourished children. World Health Orgnaization Regional Office for South-East Asia."},{"key":"ref5","unstructured":"World Health Organization (1999) Management of severe malnutrition: a manual for physicians and other senior health workers. WHO, Geneva."},{"key":"ref6","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/j.trstmh.2008.10.029","article-title":"HIV prevalence and mortality among children undergoing treatment for severe acute malnutrition in sub-Saharan Africa: a systematic review and meta-analysis","volume":"103","author":"P Fergusson","year":"2009","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3310\/hta16190","article-title":"The effectiveness of interventions to treat severe acute malnutrition in young children: a systematic review","volume":"16","author":"J Picot","year":"2012","journal-title":"Health Technol Assess"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1056\/NEJMoa1202851","article-title":"Antibiotics as part of the management of severe acute malnutrition","volume":"368","author":"I Trehan","year":"2013","journal-title":"N Engl J Med"},{"key":"ref9","unstructured":"UN Interagency Group for Child Mortality Estimation (2012) Levels and Trends in Child Mortality, Report 2012."},{"key":"ref10","unstructured":"World Health Organization (2012) World Health Statistics 2010. WHO website. Available: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.who.int\/whosis\/whostat\/2010\/en\/index.html\" xlink:type=\"simple\">http:\/\/www.who.int\/whosis\/whostat\/2010\/en\/index.html<\/ext-link>. Accessed 2013 Jun 10."},{"key":"ref11","unstructured":"Institut National de la Statistique (INS), Macro International Inc. (2007) Enqu\u00eate D\u00e9mographique et de Sant\u00e9 et \u00e0 Indicateurs Multiples du Niger 2006. Calverton, Maryland, USA : INS et Macro International Inc."},{"key":"ref12","unstructured":"World Health Organization, World Food Programme, United Nations System Standing Committee, United Nations Children\u2019s Fund (2007) Community-based management of severe acute malnutrition."},{"key":"ref13","unstructured":"World Health Organization, United Nations Children\u2019s Fund (2009) WHO child growth standards and the identification of severe acute malnutrition in infants and children. WHO website. <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.who.int\/nutrition\/publications\/severemalnutrition\/9789241598163\/en\/index.html\" xlink:type=\"simple\">http:\/\/www.who.int\/nutrition\/publications\/severemalnutrition\/9789241598163\/en\/index.html<\/ext-link>. Accessed 2013 Jun 10."},{"key":"ref14","unstructured":"Courvalin P, Leclercq R, Bingen E (2006) Antiobiogramme."},{"key":"ref15","unstructured":"World Health Organization (2012) WHO information for molecular diagnosis of influenza virus in humans - update. WHO website. <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.who.int\/influenza\/resources\/documents\/molecular_diagnosis_influenza_virus_humans_update_201108.pdf\" xlink:type=\"simple\">http:\/\/www.who.int\/influenza\/resources\/documents\/molecular_diagnosis_influenza_virus_humans_update_201108.pdf<\/ext-link>. Accessed 2013 Jun 10."},{"key":"ref16","unstructured":"World Health Organization (2005) Handbook: IMCI integrated management of childhood illness."},{"key":"ref17","unstructured":"World Health Organization (2005) Hospital care for children; Guidelines for the management of common illnesses with limited resources."},{"key":"ref18","unstructured":"Kliegman RP, Behrman RE, Jenson HB, Stanton BF (2007) Nelson Textbook of Pediatrics; 18th Edition."},{"key":"ref19","unstructured":"World Health Organization (2011) Haemoglobin concentrations for the diagnosis of anaemia and assessment of severity. Vitamin and Mineral Nutrition Information System. WHO website. <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.who.int\/vmnis\/indicators\/haemoglobin.pdf\" xlink:type=\"simple\">http:\/\/www.who.int\/vmnis\/indicators\/haemoglobin.pdf<\/ext-link>. Accessed 2013 Jun 10."},{"key":"ref20","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1097\/01.PCC.0000149131.72248.E6","article-title":"International pediatric sepsis consensus conference: definitions for sepsis and organ dysfunction in pediatrics","volume":"6","author":"B Goldstein","year":"2005","journal-title":"Pediatr Crit Care Med"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/S0399-077X(05)80013-7","article-title":"Consensus conferences on antimicrobial therapy societe de pathologie infectieuse de langue francaise antibiotherapy of urinary tract infections November 16th 1990","volume":"21","author":"fran\u00e7aise Societe de pathologie infectieuse de langue","year":"1991","journal-title":"M\u00e9decine et Maladies Infectieuses"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1093\/cid\/cir522","article-title":"Massive increase, spread, and exchange of extended spectrum beta-lactamase-encoding genes among intestinal Enterobacteriaceae in hospitalized children with severe acute malnutrition in Niger","volume":"53","author":"PL Woerther","year":"2011","journal-title":"Clin Infect Dis"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1186\/1471-2334-6-160","article-title":"Bacteraemia among severely malnourished children infected and uninfected with the human immunodeficiency virus-1 in Kampala, Uganda","volume":"6","author":"H Bachou","year":"2006","journal-title":"BMC Infect Dis"},{"key":"ref24","first-page":"343","article-title":"Bacterial isolates in severely malnourished children at Kenyatta National Hospital, Nairobi","volume":"82","author":"N Noorani","year":"2005","journal-title":"East Afr Med J"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1056\/NEJMoa040275","article-title":"Bacteremia among children admitted to a rural hospital in Kenya","volume":"352","author":"JA Berkley","year":"2005","journal-title":"N Engl J Med"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"e500","DOI":"10.1371\/journal.pmed.0030500","article-title":"Children with severe malnutrition: can those at highest risk of death be identified with the WHO protocol?","volume":"3","author":"K Maitland","year":"2006","journal-title":"PLoS Med"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1080\/02724936.1996.11747805","article-title":"Bacteraemia in malnourished rural African children","volume":"16","author":"RP Reed","year":"1996","journal-title":"Ann Trop Paediatr"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1111\/j.1365-3156.2009.02364.x","article-title":"Pneumonia in severely malnourished children in developing countries - mortality risk, aetiology and validity of WHO clinical signs: a systematic review","volume":"14","author":"MJ Chisti","year":"2009","journal-title":"Trop Med Int Health"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/S0140-6736(09)60073-8","article-title":"Non-typhoidal salmonellae: a management challenge for children with community-acquired invasive disease in tropical African countries","volume":"373","author":"SM Graham","year":"2009","journal-title":"Lancet"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1097\/QCO.0b013e32833dd25d","article-title":"Nontyphoidal salmonellosis in Africa","volume":"23","author":"SM Graham","year":"2010","journal-title":"Curr Opin Infect Dis"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/S1473-3099(10)70072-4","article-title":"Community-acquired bloodstream infections in Africa: a systematic review and meta-analysis","volume":"10","author":"EA Reddy","year":"2010","journal-title":"Lancet Infect Dis"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1186\/1471-2334-7-43","article-title":"Antimicrobial resistance predicts death in Tanzanian children with bloodstream infections: a prospective cohort study","volume":"7","author":"B Blomberg","year":"2007","journal-title":"BMC Infect Dis"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"429","DOI":"10.3855\/jidc.413","article-title":"Invasive bacteria isolates from children with severe infections in a Nigerian hospital","volume":"3","author":"AO Onipede","year":"2009","journal-title":"J Infect Dev Ctries"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1097\/INF.0b013e3181792621","article-title":"Leuconostoc bacteremia in pediatric patients with short bowel syndrome: case series and review","volume":"27","author":"D Florescu","year":"2008","journal-title":"Pediatr Infect Dis J"},{"key":"ref35","doi-asserted-by":"crossref","unstructured":"Gonzalez Cortes R, Gomez Carrasco JA, Penin Anton M, Ruano Dominguez D, Garcia de Frias JE (2009) [Leuconostoc sepsis in a 2 month old malnourished patient]. An Pediatr (Barc) 71: 271. S1695\u20134033(09)00323\u20133 [pii]; 10.1016\/j.anpedi.2009.05.005 [doi].","DOI":"10.1016\/j.anpedi.2009.05.005"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1093\/jac\/dki145","article-title":"Invasive Gram-negative bacilli are frequently resistant to standard antibiotics for children admitted to hospital in Kilifi, Kenya","volume":"56","author":"P Bejon","year":"2005","journal-title":"J Antimicrob Chemother"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0068699","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,9]],"date-time":"2020-05-09T04:42:19Z","timestamp":1588999339000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0068699"}},"subtitle":[],"editor":[{"given":"Lorenz","family":"von Seidlein","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2013,7,17]]},"references-count":36,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2013,7,17]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0068699","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,7,17]]}}}