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implantation","volume":"143","author":"LC Kao","year":"2002","journal-title":"Endocrinology"},{"key":"ref91","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1210\/jc.2005-0769","article-title":"Dickkopf-1, an inhibitor of Wnt signaling, is regulated by progesterone in human endometrial stromal cells","volume":"91","author":"S Tulac","year":"2006","journal-title":"J Clin Endocrinol Metab"},{"key":"ref92","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1530\/REP-07-0191","article-title":"Dickkopf-1 secreted by decidual cells promotes trophoblast cell invasion during murine placentation","volume":"135","author":"S Peng","year":"2008","journal-title":"Reproduction"},{"key":"ref93","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1038\/srep01266","article-title":"Canonical WNT signaling regulates development of bovine embryos to the blastocyst stage","volume":"3","author":"AC Denicol","year":"2013","journal-title":"Scientific 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Ledgard","year":"2011","journal-title":"Reprod Fertil Dev"},{"key":"ref100","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1530\/jrf.0.0920475","article-title":"Survival of bovine embryos transferred to progesterone-treated asynchronous recipients","volume":"92","author":"RD Geisert","year":"1991","journal-title":"J Reprod Fertil"},{"key":"ref101","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1111\/j.1439-0442.1993.tb00667.x","article-title":"The effect of intensive flunixin treatment during the postpartum period in the bovine","volume":"40","author":"K Odensvik","year":"1993","journal-title":"Zentralblatt fur Veterinarmedizin Reihe A"},{"key":"ref102","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1071\/RD11225","article-title":"Effect of asynchronous transfer on bovine embryonic development and relationship with early cycle uterine proteome profiles","volume":"24","author":"AM Ledgard","year":"2012","journal-title":"Reprod Fertil 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