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In: Baron S, editor. Medical Microbiology. 4th ed. Galveston (TX)."},{"key":"ref80","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/S1084-2756(02)90115-6","article-title":"Neonatal herpes infection: diagnosis, treatment and prevention","volume":"7","author":"AM Enright","year":"2002","journal-title":"Semin Neonatol"},{"key":"ref81","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1080\/00313020701813792","article-title":"Viruses and other infections in stillbirth: what is the evidence and what should we be doing?","volume":"40","author":"WD Rawlinson","year":"2008","journal-title":"Pathology"},{"key":"ref82","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1089\/scd.2010.0379","article-title":"Amniotic mesenchymal stem cells enhance normal fetal wound healing","volume":"20","author":"JD Klein","year":"2011","journal-title":"Stem Cells Dev"},{"key":"ref83","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1038\/leu.2010.310","article-title":"Human but not murine multipotent mesenchymal stromal cells exhibit broad-spectrum antimicrobial effector function mediated by indoleamine 2,3-dioxygenase","volume":"25","author":"R Meisel","year":"2011","journal-title":"Leukemia"},{"key":"ref84","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1002\/rmv.368","article-title":"Viral induction of site-specific chromosome damage","volume":"13","author":"EA Fortunato","year":"2003","journal-title":"Rev Med Virol"},{"key":"ref85","doi-asserted-by":"crossref","first-page":"2169","DOI":"10.1126\/science.296.5576.2169","article-title":"Cells exchanged during pregnancy live on","volume":"296","author":"M Barinaga","year":"2002","journal-title":"Science"},{"key":"ref86","doi-asserted-by":"crossref","first-page":"4701","DOI":"10.1128\/JVI.02748-06","article-title":"Developmental regulation of human cytomegalovirus receptors in cytotrophoblasts correlates with distinct replication sites in the placenta","volume":"81","author":"E Maidji","year":"2007","journal-title":"J Virol"},{"key":"ref87","doi-asserted-by":"crossref","first-page":"1727","DOI":"10.1002\/stem.720","article-title":"Effects on proliferation and differentiation of multipotent bone marrow stromal cells engineered to express growth factors for combined cell and gene therapy","volume":"29","author":"FA Fierro","year":"2011","journal-title":"Stem Cells"},{"key":"ref88","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1007\/978-1-4614-2098-9_17","article-title":"New tools in regenerative medicine: gene therapy","volume":"741","author":"M Munoz Ruiz","year":"2012","journal-title":"Adv Exp Med Biol"},{"key":"ref89","doi-asserted-by":"crossref","first-page":"44","DOI":"10.2174\/157488809787169138","article-title":"Stem cells as vectors to deliver HSV\/tk gene therapy for malignant gliomas","volume":"4","author":"P Rath","year":"2009","journal-title":"Curr Stem Cell Res Ther"},{"key":"ref90","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1038\/gt.2011.15","article-title":"Lentiviral vectors for induction of self-differentiation and conditional ablation of dendritic cells","volume":"18","author":"M Pincha","year":"2011","journal-title":"Gene Ther"},{"key":"ref91","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1007\/s12033-012-9522-y","article-title":"Enhanced adenovirus transduction of hMSCs using 3D hydrogel cell carriers","volume":"53","author":"AJ Neumann","year":"2013","journal-title":"Mol Biotechnol"},{"key":"ref92","doi-asserted-by":"crossref","first-page":"1376","DOI":"10.1016\/j.biomaterials.2011.10.078","article-title":"Enhancement of MSC adhesion and therapeutic efficiency in ischemic heart using lentivirus delivery with periostin","volume":"33","author":"YH Cho","year":"2012","journal-title":"Biomaterials"},{"key":"ref93","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1634\/stemcells.19-5-358","article-title":"Multiple applications for replication-defective herpes simplex virus vectors","volume":"19","author":"EA Burton","year":"2001","journal-title":"Stem Cells"},{"key":"ref94","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1002\/jgm.1506","article-title":"Hybrid herpes simplex virus\/Epstein-Barr virus amplicon viral vectors confer enhanced transgene expression in primary human tumors and human bone marrow-derived mesenchymal stem cells","volume":"12","author":"KC Sia","year":"2010","journal-title":"J Gene Med"}],"container-title":["PLoS 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