{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T00:57:35Z","timestamp":1790470655795,"version":"4.1.0"},"reference-count":50,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2013,8,22]],"date-time":"2013-08-22T00:00:00Z","timestamp":1377129600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0072290","type":"journal-article","created":{"date-parts":[[2013,8,22]],"date-time":"2013-08-22T21:29:47Z","timestamp":1377206987000},"page":"e72290","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":55,"title":["Infection of Type I Interferon Receptor-Deficient Mice with Various Old World Arenaviruses: A Model for Studying Virulence and Host Species Barriers"],"prefix":"10.1371","volume":"8","author":[{"given":"Toni","family":"Rieger","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doron","family":"Merkler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephan","family":"G\u00fcnther","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2013,8,22]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"670","DOI":"10.4269\/ajtmh.1970.19.670","article-title":"Lassa fever, a new virus disease of man from West Africa. I. Clinical description and pathological findings","volume":"19","author":"JD Frame","year":"1970","journal-title":"Am J Trop Med Hyg"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"e388","DOI":"10.1371\/journal.pntd.0000388","article-title":"Risk maps of Lassa fever in West Africa","volume":"3","author":"E Fichet-Calvet","year":"2009","journal-title":"PLOS Negl Trop Dis"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.3201\/eid1607.100146","article-title":"Detection of Lassa virus, Mali","volume":"16","author":"D Safronetz","year":"2010","journal-title":"Emerg Infect Dis"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1080\/10408360490497456","article-title":"Lassa virus","volume":"41","author":"S G\u00fcnther","year":"2004","journal-title":"Crit Rev Clin Lab Sci"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1136\/bmj.311.7009.857","article-title":"Review of cases of nosocomial Lassa fever in Nigeria: the high price of poor medical practice","volume":"311","author":"SP Fisher-Hoch","year":"1995","journal-title":"Bmj"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"e1839","DOI":"10.1371\/journal.pntd.0001839","article-title":"Molecular diagnostics for Lassa fever at Irrua specialist teaching hospital, Nigeria: lessons learnt from two years of laboratory operation","volume":"6","author":"DA Asogun","year":"2012","journal-title":"PLOS Negl Trop Dis"},{"key":"ref7","first-page":"441","article-title":"Isolation of an arenavirus closely related to Lassa virus from Mastomys natalensis in south-east Africa","volume":"55","author":"H Wulff","year":"1977","journal-title":"Bull World Health Organ"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1159\/000149344","article-title":"An arenavirus isolated from wild-caught rodents (Praomys species) in the Central African Republic","volume":"19","author":"JP Gonzalez","year":"1983","journal-title":"Intervirology"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"2008","DOI":"10.3201\/eid1512.090864","article-title":"Mopeia virus-related arenavirus in natal multimammate mice, Morogoro, Tanzania","volume":"15","author":"S G\u00fcnther","year":"2009","journal-title":"Emerg Infect Dis"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.4269\/ajtmh.1981.30.1291","article-title":"Recovery of a Lassa-related arenavirus in Zimbabwe","volume":"30","author":"KM Johnson","year":"1981","journal-title":"Am J Trop Med Hyg"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1126\/science.185.4147.263","article-title":"Lassa virus isolation from Mastomys natalensis rodents during an epidemic in Sierra Leone","volume":"185","author":"TP Monath","year":"1974","journal-title":"Science"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"1971","DOI":"10.3201\/eid1212.060812","article-title":"Mastomys natalensis and Lassa fever, West Africa","volume":"12","author":"E Lecompte","year":"2006","journal-title":"Emerg Infect Dis"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"e20893","DOI":"10.1371\/journal.pone.0020893","article-title":"Novel arenavirus sequences in Hylomyscus sp. and Mus (Nannomys) setulosus from C\u00f4te d\u2019Ivoire: implications for evolution of arenaviruses in Africa","volume":"6","author":"D Coulibaly-N\u2019Golo","year":"2011","journal-title":"PLOS ONE"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"8293","DOI":"10.1128\/JVI.02120-10","article-title":"Human dendritic cells infected with the nonpathogenic Mopeia virus induce stronger T-cell responses than those infected with Lassa virus","volume":"85","author":"D Pannetier","year":"2011","journal-title":"J Virol"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"2861","DOI":"10.4049\/jimmunol.172.5.2861","article-title":"Lassa virus infection of human dendritic cells and macrophages is productive but fails to activate cells","volume":"172","author":"S Baize","year":"2004","journal-title":"J Immunol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"2797","DOI":"10.4049\/jimmunol.170.6.2797","article-title":"Cutting edge: impairment of dendritic cells and adaptive immunity by Ebola and Lassa viruses","volume":"170","author":"S Mahanty","year":"2003","journal-title":"J Immunol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"e1000836","DOI":"10.1371\/journal.ppat.1000836","article-title":"T cell-dependence of Lassa fever pathogenesis","volume":"6","author":"L Flatz","year":"2010","journal-title":"PLOS Pathog"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"401","DOI":"10.4269\/ajtmh.1986.35.401","article-title":"Lassa virus hepatitis: a study of fatal Lassa fever in humans","volume":"35","author":"JB McCormick","year":"1986","journal-title":"Am J Trop Med Hyg"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S1286-4579(01)01508-8","article-title":"Monitoring of clinical and laboratory data in two cases of imported Lassa fever","volume":"4","author":"H Schmitz","year":"2002","journal-title":"Microbes Infect"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"5890","DOI":"10.1128\/JVI.01948-08","article-title":"Early and strong immune responses are associated with control of viral replication and recovery in lassa virus-infected cynomolgus monkeys","volume":"83","author":"S Baize","year":"2009","journal-title":"J Virol"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1186\/1743-422X-8-314","article-title":"Capacity building permitting comprehensive monitoring of a severe case of Lassa hemorrhagic fever in Sierra Leone with a positive outcome: case report","volume":"8","author":"JN Grove","year":"2011","journal-title":"Virol J"},{"key":"ref22","first-page":"197","article-title":"Lassa fever encephalopathy: clinical and laboratory findings","volume":"95","author":"D Cummins","year":"1992","journal-title":"J Trop Med Hyg"},{"key":"ref23","first-page":"349","article-title":"Pathologic and virologic study of fatal Lassa fever in man","volume":"107","author":"DH Walker","year":"1982","journal-title":"Am J Pathol"},{"key":"ref24","first-page":"535","article-title":"The pathology of human Lassa fever","volume":"52","author":"WC Winn Jr.","year":"1975","journal-title":"Bull World Health Organ"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1093\/infdis\/141.5.580","article-title":"Lassa virus infection of rhesus monkeys: pathogenesis and treatment with ribavirin","volume":"141","author":"PB Jahrling","year":"1980","journal-title":"J Infect Dis"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1093\/infdis\/146.3.360","article-title":"Experimental infection of rhesus monkeys with Lassa virus and a closely related arenavirus, Mozambique virus","volume":"146","author":"DH Walker","year":"1982","journal-title":"J Infect Dis"},{"key":"ref27","first-page":"261","article-title":"Experimental Lassa virus infection in the squirrel monkey","volume":"80","author":"DH Walker","year":"1975","journal-title":"Am J Pathol"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.4269\/ajtmh.1982.31.1038","article-title":"Pathology of Lassa virus infection in the rhesus monkey","volume":"31","author":"RT Callis","year":"1982","journal-title":"Am J Trop Med Hyg"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1128\/IAI.37.2.771-778.1982","article-title":"Pathogenesis of Lassa virus infection in guinea pigs","volume":"37","author":"PB Jahrling","year":"1982","journal-title":"Infect Immun"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/0035-9203(85)90386-4","article-title":"Endemic Lassa fever in Liberia. III. Characterization of Lassa virus isolates","volume":"79","author":"PB Jahrling","year":"1985","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"999","DOI":"10.4269\/ajtmh.1985.34.999","article-title":"Kinetic study of platelets and fibrinogen in Lassa virus-infected monkeys and early pathologic events in Mopeia virus-infected monkeys","volume":"34","author":"JV Lange","year":"1985","journal-title":"Am J Trop Med Hyg"},{"key":"ref32","first-page":"523","article-title":"Comparative pathology of Lassa virus infection in monkeys, guinea-pigs, and Mastomys natalensis","volume":"52","author":"DH Walker","year":"1975","journal-title":"Bull World Health Organ"},{"key":"ref33","first-page":"5","article-title":"Experimental studies of arenaviral hemorrhagic fevers","volume":"134","author":"CJ Peters","year":"1987","journal-title":"Curr Top Microbiol Immunol"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1016\/S0140-6736(79)90659-7","article-title":"Protection of rhesus monkeys from Lassa virus by immunisation with closely related Arenavirus","volume":"2","author":"MP Kiley","year":"1979","journal-title":"Lancet"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"3389","DOI":"10.1128\/JVI.06284-11","article-title":"Functional interferon system is required for clearance of lassa virus","volume":"86","author":"NE Yun","year":"2012","journal-title":"J Virol"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"5670","DOI":"10.1128\/JVI.00272-10","article-title":"Lambda interferon renders epithelial cells of the respiratory and gastrointestinal tracts resistant to viral infections","volume":"84","author":"M Mordstein","year":"2010","journal-title":"J Virol"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"e1000412","DOI":"10.1371\/journal.pbio.1000412","article-title":"Improving bioscience research reporting: The ARRIVE guidelines for reporting animal research","volume":"8","author":"C Kilkenny","year":"2010","journal-title":"PLOS Biol"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"466","DOI":"10.3201\/eid0605.000504","article-title":"Imported Lassa fever in Germany: molecular characterization of a new Lassa virus strain","volume":"6","author":"S G\u00fcnther","year":"2000","journal-title":"Emerg Infect Dis"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"1642","DOI":"10.3201\/eid1110.041343","article-title":"Lassa fever, Nigeria, 2003 and 2004","volume":"11","author":"SA Omilabu","year":"2005","journal-title":"Emerg Infect Dis"},{"key":"ref40","first-page":"631","article-title":"Immunoglobulin M and G responses measured by immunofluorescence in patients with Lassa or Marburg virus infections","volume":"57","author":"H Wulff","year":"1979","journal-title":"Bull World Health Organ"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"1918","DOI":"10.1126\/science.8009221","article-title":"Functional role of type I and type II interferons in antiviral defense","volume":"264","author":"U M\u00fcller","year":"1994","journal-title":"Science"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1007\/BF01313953","article-title":"Epitope mapping of the Lassa virus nucleoprotein using monoclonal anti-nucleocapsid antibodies","volume":"106","author":"FT Hufert","year":"1989","journal-title":"Arch Virol"},{"key":"ref43","first-page":"176","article-title":"Effect of sex and age on serum biochemical reference ranges in C57BL\/6J mice","volume":"54","author":"X Zhou","year":"2004","journal-title":"Comp Med"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1503\/cmaj.1040752","article-title":"Liver enzyme alteration: a guide for clinicians","volume":"172","author":"EG Giannini","year":"2005","journal-title":"CMAJ"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1086\/322033","article-title":"Lassa fever encephalopathy: Lassa virus in cerebrospinal fluid but not in serum","volume":"184","author":"S G\u00fcnther","year":"2001","journal-title":"J Infect Dis"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1016\/0042-6822(92)90514-P","article-title":"Generation of reassortants between African arenaviruses","volume":"188","author":"IS Lukashevich","year":"1992","journal-title":"Virology"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"12518","DOI":"10.1128\/JVI.05091-11","article-title":"Cross-species analysis of the replication complex of Old World arenaviruses reveals two nucleoprotein sites involved in L protein function","volume":"85","author":"R Kerber","year":"2011","journal-title":"J Virol"},{"key":"ref48","first-page":"282","article-title":"Reproduction of Lassa virus in different cell cultures","volume":"27","author":"IS Lukashevich","year":"1983","journal-title":"Acta Virol"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"11330","DOI":"10.1128\/JVI.00763-09","article-title":"Identification of amino acid residues critical for the anti-interferon activity of the nucleoprotein of the prototypic arenavirus lymphocytic choriomeningitis virus","volume":"83","author":"L Mart\u00ednez-Sobrido","year":"2009","journal-title":"J Virol"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"9192","DOI":"10.1128\/JVI.00555-06","article-title":"Inhibition of the type I interferon response by the nucleoprotein of the prototypic arenavirus lymphocytic choriomeningitis virus","volume":"80","author":"L Mart\u00ednez-Sobrido","year":"2006","journal-title":"J Virol"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0072290","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,2]],"date-time":"2020-08-02T11:24:17Z","timestamp":1596367457000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0072290"}},"subtitle":[],"editor":[{"given":"Daniel\u00a0G.","family":"Bausch","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2013,8,22]]},"references-count":50,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2013,8,22]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0072290","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,8,22]]}}}