{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T21:02:46Z","timestamp":1793826166353,"version":"4.6.1"},"reference-count":61,"publisher":"Public Library of Science (PLoS)","issue":"9","license":[{"start":{"date-parts":[[2013,9,27]],"date-time":"2013-09-27T00:00:00Z","timestamp":1380240000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0073164","type":"journal-article","created":{"date-parts":[[2013,9,27]],"date-time":"2013-09-27T17:26:37Z","timestamp":1380302797000},"page":"e73164","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":63,"title":["Contribution of Corticospinal Tract and Functional Connectivity in Hand Motor Impairment after Stroke"],"prefix":"10.1371","volume":"8","author":[{"given":"Charlotte","family":"Rosso","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Romain","family":"Valabregue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yohan","family":"Attal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Vargas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie","family":"Gaudron","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flore","family":"Baronnet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Bertasi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fr\u00e9d\u00e9ric","family":"Humbert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Peskine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Perlbarg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Habib","family":"Benali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"St\u00e9phane","family":"Leh\u00e9ricy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yves","family":"Samson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2013,9,27]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1093\/brain\/awr033","article-title":"Reorganization of cerebral networks after stroke: new insights from neuroimaging with connectivity approaches","volume":"134","author":"C Grefkes","year":"2011","journal-title":"Brain"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1007\/s00429-009-0220-x","article-title":"Imaging the relationship between structure, function and behaviour in the human brain","volume":"213","author":"H Johansen-Berg","year":"2009","journal-title":"Brain Struct Funct"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"8","DOI":"10.3389\/fnsys.2011.00008","article-title":"Functional connectivity in relation to motor performance and recovery after stroke","volume":"5","author":"KP Westlake","year":"2011","journal-title":"Front Syst Neurosci"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1212\/01.WNL.0000140468.92212.BE","article-title":"Modulation of the BOLD-response in early recovery from sensorimotor stroke","volume":"63","author":"F Binkofski","year":"2004","journal-title":"Neurology"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1136\/jnnp.2009.190512","article-title":"The relationship between motor deficit and primary motor cortex hemispheric activation balance after stroke: longitudinal fMRI study","volume":"81","author":"C Calautti","year":"2010","journal-title":"J Neurol Neurosurg, Psychiatry"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"1610","DOI":"10.1161\/01.STR.0000017100.68294.52","article-title":"Longitudinal study of motor recovery after stroke: recruitment and focusing of brain activation","volume":"33","author":"A Feydy","year":"2002","journal-title":"Stroke"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1093\/brain\/awh456","article-title":"Vicarious function within the human primary motor cortex? A longitudinal fMRI stroke study","volume":"128","author":"A Jaillard","year":"2005","journal-title":"Brain"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1097\/00001756-200307180-00004","article-title":"Cortical reorganization associated with motor recovery in hemiparetic stroke patients","volume":"14","author":"SH Jang","year":"2003","journal-title":"Neuroreport"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1097\/00001756-200403010-00002","article-title":"Cortical activation changes associated with motor recovery in patients with precentral knob infarct","volume":"15","author":"SH Jang","year":"2004","journal-title":"Neuroreport"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"2166","DOI":"10.1016\/j.neuroimage.2003.08.017","article-title":"Correlation between cerebral reorganization and motor recovery after subcortical infarcts","volume":"20","author":"I Loubinoux","year":"2003","journal-title":"Neuroimage"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"2980","DOI":"10.1093\/cercor\/bhm023","article-title":"Prognostic value of FMRI in recovery of hand function in subcortical stroke patients","volume":"17","author":"I Loubinoux","year":"2007","journal-title":"Cereb Cortex"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1161\/01.STR.31.3.656","article-title":"Evolution of cortical activation during recovery from corticospinal tract infarction","volume":"31","author":"RS Marshall","year":"2000","journal-title":"Stroke"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1093\/cercor\/bhq140","article-title":"The role of the contralesional motor cortex for motor recovery in the early days after stroke assessed with longitudinal FMRI","volume":"21","author":"AK Rehme","year":"2011","journal-title":"Cereb Cortex"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.1093\/brain\/awf148","article-title":"Cerebellar hemispheric activation ipsilateral to the paretic hand correlates with functional recovery after stroke","volume":"125","author":"SL Small","year":"2002","journal-title":"Brain"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1016\/j.neuroimage.2004.07.058","article-title":"A longitudinal fMRI study: in recovering and then in clinically stable sub-cortical stroke patients","volume":"23","author":"D Tombari","year":"2004","journal-title":"NeuroImage"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"1430","DOI":"10.1093\/brain\/awg145","article-title":"Neural correlates of outcome after stroke: a cross-sectional fMRI study","volume":"126","author":"NS Ward","year":"2003","journal-title":"Brain"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1177\/1545968306286322","article-title":"Longitudinal changes in cerebral response to proprioceptive input in individual patients after stroke: an FMRI study","volume":"20","author":"NS Ward","year":"2006","journal-title":"Neurorehabil Neural Repair"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1177\/1545968310364058","article-title":"Functional neuroimaging studies of early upper limb recovery after stroke: a systematic review of the literature","volume":"24","author":"FE Buma","year":"2010","journal-title":"Neurorehabil Neural Repair"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1097\/NPT.0b013e31819824f0","article-title":"Reorganization of brain function during force production after stroke: a systematic review of the literature","volume":"33","author":"KJ Kokotilo","year":"2009","journal-title":"J Neurol Phys Ther"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"2771","DOI":"10.1016\/j.neuroimage.2011.10.023","article-title":"Activation likelihood estimation meta-analysis of motor-related neural activity after stroke","volume":"59","author":"AK Rehme","year":"2012","journal-title":"NeuroImage"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1212\/WNL.0b013e3181ccc758","article-title":"Stroke recovery: the pyramid in focus","volume":"74","author":"RJ Seitz","year":"2010","journal-title":"Neurology"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.neulet.2007.08.049","article-title":"Motor outcome according to the integrity of the corticospinal tract determined by diffusion tensor tractography in the early stage of corona radiata infarct","volume":"426","author":"SH Cho","year":"2007","journal-title":"Neurosci Lett"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1212\/WNL.0b013e3181ccc6d9","article-title":"Structural integrity of corticospinal motor fibers predicts motor impairment in chronic stroke","volume":"74","author":"R Lindenberg","year":"2010","journal-title":"Neurology"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.3174\/ajnr.A2038","article-title":"Wallerian degeneration in the corticospinal tract evaluated by diffusion tensor imaging correlates with motor deficit 30 days after middle cerebral artery ischemic stroke","volume":"31","author":"J Puig","year":"2010","journal-title":"AJNR Am J Neuroradiol"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1212\/WNL.0b013e3181f39aa0","article-title":"Diffusion tensor imaging, permanent pyramidal tract damage, and outcome in subcortical stroke","volume":"75","author":"B Radlinska","year":"2010","journal-title":"Neurology"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"3461","DOI":"10.1002\/hbm.20770","article-title":"Microstructural status of ipsilesional and contralesional corticospinal tract correlates with motor skill in chronic stroke patients","volume":"30","author":"JD Schaechter","year":"2009","journal-title":"Hum Brain Mapp"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1177\/1545968309348310","article-title":"The role of corticospinal tract damage in chronic motor recovery and neurorehabilitation: a pilot study","volume":"24","author":"A Sterr","year":"2010","journal-title":"Neurorehabil Neural Repair"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1161\/STROKEAHA.109.577023","article-title":"Lesion load of the corticospinal tract predicts motor impairment in chronic stroke","volume":"41","author":"LL Zhu","year":"2010","journal-title":"Stroke"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/0924-980X(96)95656-8","article-title":"Magnetic transcranial stimulation in acute stroke: early excitation threshold and functional prognosis","volume":"101","author":"A Catano","year":"1996","journal-title":"Electroencephalogr Clin Neurophysiol"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"430","DOI":"10.2340\/16501977-0793","article-title":"Combined study of transcranial magnetic stimulation and diffusion tensor tractography for prediction of motor outcome in patients with corona radiata infarct","volume":"43","author":"YH Kwon","year":"2011","journal-title":"J Rehabil Med"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1093\/brain\/awl333","article-title":"Functional potential in chronic stroke patients depends on corticospinal tract integrity","volume":"130","author":"CM Stinear","year":"2007","journal-title":"Brain"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1177\/1545968311411054","article-title":"Upstream dysfunction of somatomotor functional connectivity after corticospinal damage in stroke","volume":"26","author":"AR Carter","year":"2012","journal-title":"Neurorehabil Neural Repair"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1002\/ana.21228","article-title":"Cortical connectivity after subcortical stroke assessed with functional magnetic resonance imaging","volume":"63","author":"C Grefkes","year":"2008","journal-title":"Ann Neurol"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1016\/j.neuroimage.2011.01.014","article-title":"Dynamic causal modeling of cortical activity from the acute to the chronic stage after stroke","volume":"55","author":"AK Rehme","year":"2011","journal-title":"NeuroImage"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1002\/ana.21810","article-title":"Motor imagery after stroke: relating outcome to motor network connectivity","volume":"66","author":"N Sharma","year":"2009","journal-title":"Ann Neurol"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"2941","DOI":"10.1002\/hbm.21417","article-title":"Degeneration of corpus callosum and recovery of motor function after stroke: A multimodal magnetic resonance imaging study","volume":"33","author":"LE Wang","year":"2012","journal-title":"Hum Brain Mapp"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"2271","DOI":"10.1016\/j.neuroimage.2012.02.070","article-title":"Why use a connectivity-based approach to study stroke and recovery of function?","volume":"62","author":"AR Carter","year":"2012","journal-title":"NeuroImage"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1113\/jphysiol.2012.243469","article-title":"Cerebral network disorders after stroke: evidence from imaging-based connectivity analyses of active and resting brain states in humans","volume":"591","author":"AK Rehme","year":"2013","journal-title":"J Physiol"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"15065","DOI":"10.1523\/JNEUROSCI.2364-11.2011","article-title":"Focal pontine lesions provide evidence that intrinsic functional connectivity reflects polyssynaptic anatomical pathways","volume":"31","author":"J Lu","year":"2011","journal-title":"J Neurosci"},{"key":"ref40","first-page":"47","article-title":"Connectivity alterations assessed by combining fMRI and MR-compatible hand robots in chronic stroke","volume":"46","author":"D Mintzopoulos","year":"2009","journal-title":"Neuroimage"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1161\/01.STR.20.7.864","article-title":"Measurements of acute cerebral infarction: a clinical examination scale","volume":"20","author":"T Brott","year":"1989","journal-title":"Stroke"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1006\/nimg.2001.0976","article-title":"The preparation and execution of self-initiated and externally-triggered movement: a study of event-related fMRI","volume":"15","author":"R Cunnington","year":"2002","journal-title":"Neuroimage"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1002\/jmri.23870","article-title":"Assessment of cortico-spinal tract (CST) damage in acute stroke patients: comparison of a tract-specific analysis versus segmentation of a CST template","volume":"37","author":"P Vargas","year":"2013","journal-title":"J Magn Reson Imaging"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1002\/jmri.21627","article-title":"Dynamic corticospinal white matter connectivity changes during stroke recovery: a diffusion tensor probabilistic tractography study","volume":"29","author":"K Pannek","year":"2009","journal-title":"J Magn Reson Imaging"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1016\/j.neuroimage.2005.08.040","article-title":"White matter fiber tracts of the human brain: three-dimensional mapping at microscopic resolution, topography and intersubject variability","volume":"29","author":"U B\u00fcrgel","year":"2006","journal-title":"NeuroImage"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"S20","DOI":"10.1038\/491S20a","article-title":"Perspective : brain scans need a rethink","volume":"491","author":"B Deen","year":"2012","journal-title":"Nature"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.mri.2006.09.042","article-title":"CORSICA: correction of structured noise in fMRI by automatic identification of ICA components","volume":"25","author":"V Perlbarg","year":"2007","journal-title":"Magn Reson Imaging"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/S0166-4328(01)00297-2","article-title":"Controlling the false discovery rate in behavior genetics research","volume":"125","author":"Y Benjamini","year":"2001","journal-title":"Behav Brain Res"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.neuroimage.2005.12.057","article-title":"Partial correlation for functional brain interactivity investigation in functional MRI","volume":"32","author":"G Marrelec","year":"2006","journal-title":"NeuroImage"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1016\/j.neuroimage.2009.08.048","article-title":"Dynamics of motor-related functional integration during motor sequence learning","volume":"49","author":"D Coynel","year":"2010","journal-title":"Neuroimage"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1136\/jnnp.2007.118463","article-title":"Ipsilateral motor dysfunction from unilateral stroke : implications for the functional neuranatomy of hemiparesis","volume":"79","author":"O Noskin","year":"2008","journal-title":"J Neurol Neurosurg, Psychiatry"},{"key":"ref52","article-title":"Practical statistics for medical research","author":"D Altman","year":"1991"},{"key":"ref53"},{"key":"ref54","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1161\/STROKEAHA.110.599340","article-title":"Anatomy of stroke injury predicts gains from therapy","volume":"42","author":"JD Riley","year":"2011","journal-title":"Stroke"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"1844","DOI":"10.1093\/brain\/awl106","article-title":"Non invasive mapping of corticofugal fibres from multiple motor areas--relevance to stroke recovery","volume":"129","author":"JM Newton","year":"2006","journal-title":"Brain"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1093\/brain\/109.4.677","article-title":"Crossed cerebellar diaschisis. Further studies","volume":"109","author":"P Pantano","year":"1986","journal-title":"Brain"},{"key":"ref57","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1161\/01.STR.17.5.817","article-title":"Diaschisis","volume":"17","author":"DM Feeney","year":"1986","journal-title":"Stroke"},{"key":"ref58","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1093\/brain\/awr313","article-title":"Cortical activation changes underlying stimulation-induced behavioural gains in chronic stroke","volume":"135","author":"CJ Stagg","year":"2012","journal-title":"Brain"},{"key":"ref59","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1177\/1545968312437940","article-title":"Theta burst stimulation in the rehabilitation of the upper limb: a semirandomized, placebo-controlled trial in chronic stroke patients","volume":"26","author":"P Talelli","year":"2012","journal-title":"Neurorehabil Neural Repair"},{"key":"ref60","first-page":"260","article-title":"Cerebellum to motor-cortex paired associative stimulation induces bidirectional STDP-like plasticity in human motor cortex","volume":"6","author":"MK Lu","year":"2012","journal-title":"Front Hum Neurosci"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/S0003-9993(95)80568-0","article-title":"Outcome and time course of recovery in stroke. Part II: Time course of recovery. The Copenhagen Stroke Study","volume":"76","author":"HS J\u00f8rgensen","year":"1995","journal-title":"Arch Phys Med Rehabil"}],"updated-by":[{"DOI":"10.1371\/annotation\/1f472957-84b4-4251-9abb-3430469b14dd","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2014,1,3]],"date-time":"2014-01-03T00:00:00Z","timestamp":1388707200000}}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0073164","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,10,23]],"date-time":"2018-10-23T19:23:41Z","timestamp":1540322621000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0073164"}},"subtitle":[],"editor":[{"given":"Wieslaw","family":"Nowinski","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2013,9,27]]},"references-count":61,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2013,9,27]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0073164","relation":{"correction":[{"id-type":"doi","id":"10.1371\/annotation\/1f472957-84b4-4251-9abb-3430469b14dd","asserted-by":"object"}]},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,9,27]]}}}