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Available: http:\/\/www1.paho.org\/English\/AD\/DPC\/CD\/RegionalPlanParaguay.pdf<\/ext-link>. Acessed 2013 March 21"},{"key":"ref16","unstructured":"World Health Organization Collaborating Centre for Drug Statistics Methodology Norwegian Institute of Public Health, (Intitution O (2012) ATC\/DDD Index. 2012. Available: http:\/\/www.whocc.no\/atc_ddd_index\/<\/ext-link>. Accessed 2012 November 12"},{"key":"ref17","unstructured":"Pan American Health Organization (n.d.) Pan American Health Organization Data Tabulator. Available: http:\/\/www.paho.org\/English\/SHA\/coredata\/tabulator\/newTabulator.htm<\/ext-link>. 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