{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,4]],"date-time":"2022-04-04T20:50:25Z","timestamp":1649105425631},"reference-count":13,"publisher":"Public Library of Science (PLoS)","issue":"10","license":[{"start":{"date-parts":[[2013,10,4]],"date-time":"2013-10-04T00:00:00Z","timestamp":1380844800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0075782","type":"journal-article","created":{"date-parts":[[2013,10,4]],"date-time":"2013-10-04T21:20:03Z","timestamp":1380921603000},"page":"e75782","update-policy":"http:\/\/dx.doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":1,"title":["Development of a Conditional Mesd (Mesoderm Development) Allele for Functional Analysis of the Low-Density Lipoprotein Receptor-Related Family in Defined Tissues"],"prefix":"10.1371","volume":"8","author":[{"given":"Andrew V.","family":"Taibi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janet K.","family":"Lighthouse","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard C.","family":"Grady","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenneth R.","family":"Shroyer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernadette C.","family":"Holdener","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2013,10,4]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/S0092-8674(03)00045-X","article-title":"<italic>Mesd<\/italic> encodes an LRP5\/6 chaperone essential for specification of mouse embryonic polarity","volume":"112","author":"JC Hsieh","year":"2003","journal-title":"Cell"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1002\/dvdy.22477","article-title":"MESD is essential for apical localization of Megalin\/LRP2 in the Visceral Endoderm","volume":"240","author":"JK Lighthouse","year":"2011","journal-title":"Dev Dynam"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.str.2010.12.022","article-title":"The structure of MESD45\u2013184 brings light into the mechanism of LDLR family folding","volume":"19","author":"C Kohler","year":"2011","journal-title":"Structure"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1146\/annurev.biochem.71.110601.135342","article-title":"Lipoprotein receptors in the nervous system","volume":"71","author":"J Herz","year":"2002","journal-title":"Annu Rev Biochem"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1515\/bc.2010.129","article-title":"Lipoprotein receptors-an evolutionarily ancient multifunctional receptor family","volume":"391","author":"M Dieckmann","year":"2010","journal-title":"Biol Chem"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/S1043-2760(01)00526-4","article-title":"Diverse roles for the LDL receptor family","volume":"13","author":"DK Strickland","year":"2002","journal-title":"Trends Endocrin Met"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1194\/jlr.R300017-JLR200","article-title":"Functions of lipoprotein receptors in neurons","volume":"45","author":"U Beffert","year":"2004","journal-title":"J Lipid Res"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/S0962-8924(02)02282-1","article-title":"The low-density lipoprotein receptor gene family: a cellular Swiss army knife?","volume":"12","author":"A Nykjaer","year":"2002","journal-title":"Trends Cell Biol"},{"key":"ref9","first-page":"19","article-title":"LRP family orchestrates cholesterol homeostasis","volume":"85","author":"A Mani","year":"2012","journal-title":"Yale J Biol Med"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1242\/dev.120.5.1335","article-title":"<italic>Msd<\/italic> Is Required for Mesoderm Induction in Mice","volume":"120","author":"BC Holdener","year":"1994","journal-title":"Development"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1002\/(SICI)1526-968X(200002)26:2<99::AID-GENE1>3.0.CO;2-B","article-title":"Cre recombinase: the universal reagent for genome tailoring","volume":"26","author":"A Nagy","year":"2000","journal-title":"Genesis"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"2812","DOI":"10.1073\/pnas.90.7.2812","article-title":"Adenovirus-mediated transfer of low density lipoprotein receptor gene acutely accelerates cholesterol clearance in normal mice","volume":"90","author":"J Herz","year":"1993","journal-title":"Proc Nat Acad Sci USA"},{"key":"ref13","first-page":"1562","article-title":"Sustained somatic gene inactivation by viral transfer of Cre recombinase","volume":"14","author":"A Rohlmann","year":"1996"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0075782","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,7]],"date-time":"2022-03-07T22:34:19Z","timestamp":1646692459000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0075782"}},"subtitle":[],"editor":[{"given":"Edward E.","family":"Schmidt","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2013,10,4]]},"references-count":13,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2013,10,4]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0075782","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,10,4]]}}}