{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T03:42:36Z","timestamp":1768016556644,"version":"3.49.0"},"reference-count":14,"publisher":"Public Library of Science (PLoS)","issue":"10","license":[{"start":{"date-parts":[[2013,10,8]],"date-time":"2013-10-08T00:00:00Z","timestamp":1381190400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0075906","type":"journal-article","created":{"date-parts":[[2013,10,8]],"date-time":"2013-10-08T21:35:33Z","timestamp":1381268133000},"page":"e75906","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":22,"title":["Increased Renal Iron Accumulation in Hypertensive Nephropathy of Salt-Loaded Hypertensive Rats"],"prefix":"10.1371","volume":"8","author":[{"given":"Yoshiro","family":"Naito","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hisashi","family":"Sawada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makiko","family":"Oboshi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aya","family":"Fujii","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinichi","family":"Hirotani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshihiro","family":"Iwasaku","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshitaka","family":"Okuhara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akiyo","family":"Eguchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daisuke","family":"Morisawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitsumasa","family":"Ohyanagi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Tsujino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tohru","family":"Masuyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2013,10,8]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1296","DOI":"10.1056\/NEJMoa041031","article-title":"Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization","volume":"351","author":"AS Go","year":"2004","journal-title":"N Engl J Med"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"2271","DOI":"10.1093\/ndt\/14.10.2271","article-title":"Hypertensive nephrosclerosis: pathogenesis and prevalence. Essential hypertension is an important cause of end-stage renal disease","volume":"14","author":"RG Luke","year":"1999","journal-title":"Nephrol Dial Transplant"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1016\/S0272-6386(12)70222-6","article-title":"Iron accumulation in human chronic renal disease","volume":"20","author":"BJ Nankivell","year":"1992","journal-title":"Am J Kidney Dis"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"3631","DOI":"10.1681\/ASN.2005050522","article-title":"Renoprotective properties of angiotensin receptor blockers beyond blood pressure lowering","volume":"16","author":"Y Izuhara","year":"2005","journal-title":"J Am Soc Nephrol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"1598","DOI":"10.1681\/ASN.V481598","article-title":"The role of tubular iron accumulation in the remnant kidney","volume":"4","author":"BJ Nankivell","year":"1994","journal-title":"J Am Soc Nephrol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1111\/j.1440-1681.1994.tb02472.x","article-title":"Lysosomal iron accumulation and tubular damage in rat puromycin nephrosis and ageing","volume":"21","author":"DC Harris","year":"1994","journal-title":"Clin Exp Pharmacol Physiol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"2192","DOI":"10.1097\/HJH.0b013e3283581a64","article-title":"Effect of Iron Restriction on Renal Damage and Mineralocorticoid Receptor Signaling in a Rat Model of Chronic Kidney Disease","volume":"30","author":"Y Naito","year":"2012","journal-title":"J Hypertens"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"H585","DOI":"10.1152\/ajpheart.00463.2008","article-title":"Adaptive response of the heart to long term anemia induced by iron deficiency","volume":"296","author":"Y Naito","year":"2009","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1161\/HYPERTENSIONAHA.110.159681","article-title":"Dietary iron restriction prevents hypertensive cardiovascular remodeling in Dahl salt-sensitive rats","volume":"57","author":"Y Naito","year":"2011","journal-title":"Hypertension"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1172\/JCI200317647","article-title":"JunD protects against chronic kidney disease by regulating paracrine mitogens","volume":"112","author":"E Pillebout","year":"2003","journal-title":"J Clin Invest"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/S0140-6736(96)01463-8","article-title":"Salt\u2013more adverse effects","volume":"348","author":"TF Antonios","year":"1996","journal-title":"Lancet"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1097\/00004872-199301000-00006","article-title":"Control of blood pressure and end-organ damage in maturing salt-loaded stroke-prone spontaneously hypertensive rats by oral angiotensin II receptor blockade","volume":"11","author":"MJ Camargo","year":"1993","journal-title":"J Hypertens"},{"key":"ref13","doi-asserted-by":"crossref","unstructured":"Fishbane S (2003) Safety in iron management. Am J Kidney Dis 41 (5 suppl): 18\u201326.","DOI":"10.1016\/S0272-6386(03)00373-1"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.clim.2006.06.010","article-title":"The transferrin receptor part I: Biology and targeting with cytotoxic antibodies for the treatment of cancer","volume":"121","author":"TR Daniels","year":"2006","journal-title":"Clinical Immunology"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0075906","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,8]],"date-time":"2022-03-08T15:29:32Z","timestamp":1646753372000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0075906"}},"subtitle":[],"editor":[{"given":"Luis Eduardo M.","family":"Quintas","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2013,10,8]]},"references-count":14,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2013,10,8]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0075906","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,10,8]]}}}