{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T20:19:05Z","timestamp":1768421945633,"version":"3.49.0"},"reference-count":45,"publisher":"Public Library of Science (PLoS)","issue":"11","license":[{"start":{"date-parts":[[2013,11,18]],"date-time":"2013-11-18T00:00:00Z","timestamp":1384732800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0079158","type":"journal-article","created":{"date-parts":[[2013,11,19]],"date-time":"2013-11-19T03:33:28Z","timestamp":1384832008000},"page":"e79158","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":19,"title":["Differences in Grain Ultrastructure, Phytochemical and Proteomic Profiles between the Two Contrasting Grain Cd-Accumulation Barley Genotypes"],"prefix":"10.1371","volume":"8","author":[{"given":"Hongyan","family":"Sun","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fangbin","family":"Cao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nanbo","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mian","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Imrul","family":"Mosaddek Ahmed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guoping","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feibo","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2013,11,18]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/S0098-8472(02)00113-2","article-title":"Four barley genotypes respond differently to cadmium: lipid peroxidation and activities of antioxidant capacity","volume":"50","author":"FB Wu","year":"2003","journal-title":"Environ Exp Bot"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"2082","DOI":"10.1016\/j.chemosphere.2006.10.014","article-title":"Identification of barley genotypes with low grain Cd accumulation and its interaction with four microelements","volume":"67","author":"F Chen","year":"2007","journal-title":"Chemosphere"},{"key":"ref3","first-page":"1","article-title":"Health effects of cadmium exposure \u2013 a review of the literature and a risk estimate","volume":"24","author":"L J\u00e4rup","year":"1998","journal-title":"Scand J Work Environ Health"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.jhazmat.2007.10.025","article-title":"Suppressive effects of magnesium oxide materials on cadmium uptake and accumulation into rice grains: II: Suppression of cadmium uptake and accumulation into rice grains due to application of magnesium oxide materials","volume":"154","author":"T Kikuchi","year":"2008","journal-title":"J Hazard Mater"},{"key":"ref5","first-page":"514","article-title":"Advances on physiological and ecological effects of cadmium on plants","volume":"20","author":"JB Zhang","year":"2000","journal-title":"Chinese J Acta Ecol Sin"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"193","DOI":"10.17221\/2205-PSE","article-title":"Root excretion and plant tolerance to cadmium toxicity - a review","volume":"53","author":"J Dong","year":"2007","journal-title":"Plant Soil Environ"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"756","DOI":"10.2134\/agronj1978.00021962007000050015x","article-title":"Differential response of soybean varieties to soil cadmium","volume":"70","author":"SF Bogess","year":"1978","journal-title":"Agron J"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"469","DOI":"10.2134\/agronj1982.00021962007400030017x","article-title":"Differential accumulations of cadmium and zinc by corn hybrids grown on soil amended with sewage sludge","volume":"74","author":"TD Hinesly","year":"1982","journal-title":"Agron J"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1080\/01904169109364255","article-title":"Genetic line effects on parameters influencing cadmium concentration in lettuce (<italic>Lactuca sativa<\/italic> L.)","volume":"14","author":"GM Thomas","year":"1991","journal-title":"J Plant Nutr"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1139\/g95-070","article-title":"Identification of RAPD markers linked to a gene govening cadmium uptake in durum wheat","volume":"38","author":"GA Penner","year":"1995","journal-title":"Genome"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1016\/j.jhazmat.2011.06.011","article-title":"Genotypic dependent effect of exogenous glutathione on Cd-induced changes in proteins, ultrastructure and antioxidant defense enzymes in rice seedlings","volume":"192","author":"Y Cai","year":"2011","journal-title":"J Hazard Mater"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"137","DOI":"10.2135\/cropsci1995.0011183X003500010025x","article-title":"Genotypic variation in kernel cadmium concentration in sunflower germplasm under varying soil conditions","volume":"35","author":"YM Li","year":"1995","journal-title":"Crop Sci"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.scitotenv.2007.10.038","article-title":"Selection and breeding of plant cultivars to minimize cadmium accumulation","volume":"390","author":"CA Grant","year":"2008","journal-title":"Sci Total Environ"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1093\/jexbot\/51.342.19","article-title":"The development and application of molecular markers for abiotic stress tolerance in barley","volume":"51","author":"BP Forster","year":"2000","journal-title":"J Exp Bot"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.chemosphere.2007.06.051","article-title":"Differences in yield components and kernel Cd accumulation in response to Cd toxicity in four barley genotypes","volume":"70","author":"FB Wu","year":"2007","journal-title":"Chemosphere"},{"key":"ref16","first-page":"11","article-title":"Mutants for rice storage proteins. 1. Screening of mutants for rice storage proteins of protein bodies in the starchy endosperm","volume":"76","author":"T Kumamura","year":"1988","journal-title":"Theor Appl Genet"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"13065","DOI":"10.1021\/jf2035912","article-title":"Calibration and prediction of amino acids in stevia leaf powder using near infrared reflectance spectroscopy","volume":"59","author":"G Li","year":"2011","journal-title":"J Agric Food Chem"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1007\/s11738-010-0554-2","article-title":"Comparative proteomic analysis of Cd-responsive proteins in wheat roots","volume":"33","author":"Y Wang","year":"2011","journal-title":"Acta Physiol Plant"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1007\/BF02702615","article-title":"Subcellular localization of cadmium in the root cells of Allium cepa by electron energy loss spectroscopy and cytochemistry","volume":"29","author":"DH Liu","year":"2004","journal-title":"J Biosci"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1002\/j.2050-0416.2009.tb00370.x","article-title":"The variation of \u03b2-amylase activity and protein fractions in barley grains as affected by genotypes and post-anthesis temperatures","volume":"115","author":"K Wei","year":"2009","journal-title":"J Inst Brew"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.jhazmat.2010.08.023","article-title":"Comparative proteomic analysis of <italic>Typha angustifolia<\/italic> leaf under chromium, cadmium and lead stress","volume":"184","author":"AM Bah","year":"2010","journal-title":"J Hazard Mater"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/S0098-8472(02)00045-X","article-title":"Phytochelatin and cadmium accumulation in wheat","volume":"49","author":"JP Stolt","year":"2003","journal-title":"Environ Exp Bot"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"2003","DOI":"10.1081\/CSS-120023233","article-title":"Interaction of cadmium and four microelements for uptake and translocation in different barley genotypes","volume":"34","author":"FB Wu","year":"2003","journal-title":"Commun Soil Sci Plant Anal"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/j.plaphy.2010.05.001","article-title":"Modulation of exogenous glutathione in antioxidant defense system against Cd stress in the two barley genotypes differing in Cd tolerance","volume":"48","author":"F Chen","year":"2010","journal-title":"Plant Physiol Biochem"},{"key":"ref25","unstructured":"World Health Organization (1972) Evaluation of certain food additives and of the contaminants mercury, lead and cadmium. FAO Nutrition Meetings Report Series No. 51. WHO Technical Report Series 505. Food and Agriculture Organization of the United Nations Rome: 33."},{"key":"ref26","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1021\/jf00120a024","article-title":"Elements in major raw agricultural crops in the United States. 1. Cadmium and lead in lettuce, peanuts, potatoes, soybeans, sweet corn, and wheat","volume":"31","author":"KA Wolnik","year":"1983","journal-title":"J Agric Food Chem"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.carbpol.2006.04.013","article-title":"Characterization and modeling of the A- and B-granule starches of wheat, triticale, and barley","volume":"67","author":"Z Ao","year":"2007","journal-title":"Carbohydrate Polymers"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1111\/j.1469-8137.2006.01940.x","article-title":"Subcellular localization of cadmium in roots and leaves of Arabidopsis thaliana","volume":"173","author":"F Van Belleghem","year":"2007","journal-title":"New Phytol"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1007\/s10535-007-0075-z","article-title":"Localization of cadmium in the root cells of Allium cepa by energy dispersive X-ray analysis","volume":"51","author":"D Liu","year":"2007","journal-title":"Biologia Plantarum"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1093\/treephys\/tps125","article-title":"Solute accumulation and elastic modulus changes in six radiata pine breeds exposed to drought","volume":"33","author":"N De Diego","year":"2013","journal-title":"Tree Physiol"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1093\/jxb\/erj073","article-title":"The significance of amino acids and amino acid-derived molecules in plant responses and adaptation to heavy metal stress","volume":"57","author":"SS Sharma","year":"2006","journal-title":"J Exp Bot"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1111\/j.1399-3054.1997.tb01026.x","article-title":"Heavy metal-induced accumulation of free proline in a metal-tolerant and a nontolerant ecotype of Silene vulgaris","volume":"101","author":"H Schat","year":"1997","journal-title":"Physiol Plant"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"5949","DOI":"10.1128\/JVI.74.13.5949-5956.2000","article-title":"Characterization of the zinc binding activity of the rubella virus nonstructural protease","volume":"74","author":"X Liu","year":"2000","journal-title":"J virol"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"4463","DOI":"10.1128\/JVI.72.5.4463-4466.1998","article-title":"The rubella virus nonstructural protease requires divalent cations for activity and functions in trans","volume":"72","author":"X Liu","year":"1998","journal-title":"J Virol"},{"key":"ref35","unstructured":"Dominguez G (1991) Determination and analysis of the sequence of the genome RNA of rubella virus. Ph.D. dissertation, Georgia State University, Atlanta."},{"key":"ref36","doi-asserted-by":"crossref","first-page":"1675","DOI":"10.1105\/tpc.003483","article-title":"Arabidopsis transcriptome profiling indicates that multiple regulatory pathways are activated during cold acclimation in addition to the CBF cold response pathway","volume":"14","author":"S Fowler","year":"2002","journal-title":"Plant Cell"},{"key":"ref37","doi-asserted-by":"crossref","unstructured":"Hejgaard J, Roberts TH (2007) Plant serpins. In: Silverman GA Lomas DA (eds) Molecular and cellular aspects of the serpinopathies and disorders in serpin activity. World Scientific, New Jersey: 279\u2013300.","DOI":"10.1142\/9789812707543_0012"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"3111","DOI":"10.1093\/jxb\/eri308","article-title":"Cucurbit phloem serpins are graft-transmissible and appear to be resistant to turnover in the sieve element-companion cell complex","volume":"56","author":"ML Petersen","year":"2005","journal-title":"J Exp Bot"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s10142-007-0059-2","article-title":"Serpins in plants and green algae","volume":"8","author":"HR Thomas","year":"2008","journal-title":"Funct Integr Genomic"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/S1011-1344(99)00031-7","article-title":"Effects of UV-B radiation on growth, photosynthesis, UV-B-absorbing compounds and NADP-malic enzyme in bean (<italic>Phaseolus vulgaris<\/italic> L) grown under different nitrogen conditions","volume":"48","author":"ME Pinto","year":"1999","journal-title":"J Photochem Photobiol B: Biol"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1007\/s10529-007-9347-0","article-title":"A cytosolic NADP-malic enzyme gene from rice (<italic>Oriza sativa<\/italic> L.) confers salt tolerance in transgenic Arabidopsis","volume":"29","author":"Y Cheng","year":"2007","journal-title":"Biotechnol Lett"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1007\/s10535-011-0030-x","article-title":"The effects of abiotic stresses on the NADP-dependent malic enzyme in the leaves of the hexaploid wheat","volume":"55","author":"ZY Fu","year":"2011","journal-title":"Biol Plant"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1104\/pp.118.4.1495","article-title":"Expression of beta-amylase from Alfalfa Taproots","volume":"118","author":"AG Joyce","year":"1998","journal-title":"Plant Physiol"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1111\/j.1399-3054.1973.tb03081.x","article-title":"Formation of proteinase inhibitors in developing barley grains","volume":"29","author":"M Kirsi","year":"1973","journal-title":"Physiol Plant"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.jcs.2006.08.013","article-title":"The identification of a barley haze active protein that influences beer haze stability: the genetic basis of a barley malt haze active protein","volume":"45","author":"LH Robinson","year":"2006","journal-title":"J Cereal Sci"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0079158","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,8]],"date-time":"2020-08-08T11:55:26Z","timestamp":1596887726000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0079158"}},"subtitle":[],"editor":[{"given":"Tai","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2013,11,18]]},"references-count":45,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2013,11,18]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0079158","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,11,18]]}}}