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ONE"},{"key":"ref66","first-page":"2695","article-title":"DD3(PCA3), a very sensitive and specific marker to detect prostate tumors","volume":"62","author":"JB de Kok","year":"2002","journal-title":"Cancer Res"},{"key":"ref67","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1093\/clinchem\/39.4.561","article-title":"Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinical medicine","volume":"39","author":"MH Zweig","year":"1993","journal-title":"Clin Chem"},{"key":"ref68","doi-asserted-by":"crossref","DOI":"10.18637\/jss.v017.i03","article-title":"The strucplot framework: visualizing multi-way contingency tables with VCD","volume":"17","author":"D Meyer","year":"2006","journal-title":"J Stat Softw"},{"key":"ref69","article-title":"Self- and Super-organizing Maps in R: The kohonen Package","volume":"21","author":"LMC Buydens","year":"2007","journal-title":"J Stat Softw"},{"key":"ref70","first-page":"99","article-title":"Supervised Kohonen networks for classification problems","author":"W Melssen","year":"2006"},{"key":"ref71","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/S0014-5793(99)00524-4","article-title":"Analysis of gene expression data using self-organizing maps","volume":"451","author":"P T\u00f6r\u00f6nen","year":"1999","journal-title":"FEBS Lett"},{"key":"ref72","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1186\/1471-2105-3-36","article-title":"Clustering of the SOM easily reveals distinct gene expression patterns: results of a reanalysis of lymphoma study","volume":"3","author":"J Wang","year":"2002","journal-title":"BMC Bioinformatics"},{"key":"ref73","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.vetpar.2009.12.025","article-title":"Serotyping of naturally <italic>Toxoplasma<\/italic> <italic>gondii<\/italic> infected meat-producing animals","volume":"169","author":"S Sousa","year":"2010","journal-title":"Vet Parasitol"},{"key":"ref74","doi-asserted-by":"crossref","first-page":"S2","DOI":"10.1186\/1745-7580-6-S2-S2","article-title":"Recent advances in B-cell epitope prediction methods","volume":"6","author":"Y El-Manzalawy","year":"2010","journal-title":"Immunome Res"},{"key":"ref75","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1110\/ps.041059505","article-title":"Benchmarking B cell epitope prediction: underperformance of existing methods","volume":"14","author":"MJ Blythe","year":"2005","journal-title":"Protein Sci"},{"key":"ref76","doi-asserted-by":"crossref","first-page":"S10","DOI":"10.1186\/1471-2105-14-S2-S10","article-title":"Prediction of B-cell epitopes using evolutionary information and propensity scales","volume":"14","author":"SY Lin","year":"2013","journal-title":"BMC Bioinformatics"},{"key":"ref77","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1016\/j.molimm.2008.09.009","article-title":"A machine-learning approach for predicting B-cell 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