{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T22:54:47Z","timestamp":1791327287773,"version":"4.3.1"},"reference-count":68,"publisher":"Public Library of Science (PLoS)","issue":"1","license":[{"start":{"date-parts":[[2014,1,17]],"date-time":"2014-01-17T00:00:00Z","timestamp":1389916800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0081604","type":"journal-article","created":{"date-parts":[[2014,1,17]],"date-time":"2014-01-17T21:36:32Z","timestamp":1389994592000},"page":"e81604","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":91,"title":["Antibiotic Resistance Determinants in a Pseudomonas putida Strain Isolated from a Hospital"],"prefix":"10.1371","volume":"9","author":[{"given":"L\u00e1zaro","family":"Molina","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zulema","family":"Udaondo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Estrella","family":"Duque","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matilde","family":"Fern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Molina-Santiago","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amalia","family":"Roca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Porcel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jes\u00fas","family":"de la Torre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Segura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Plesiat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katy","family":"Jeannot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan-Luis","family":"Ramos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2014,1,17]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1016\/S1473-3099(11)70165-7","article-title":"Characterisation of the <italic>Escherichia coli<\/italic> strain associated with an outbreak of haemolytic uraemic syndrome in Germany, 2011: a microbiological study","volume":"11","author":"M Bielaszewska","year":"2011","journal-title":"Lancet Infect Dis"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1056\/NEJMoa1106920","article-title":"Origins of the <italic>Escherichia coli<\/italic> strain causing an outbreak of hemolytic-uremic syndrome in Germany","volume":"365","author":"DA Rasko","year":"2011","journal-title":"N Engl J Med"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1111\/j.1751-7915.2009.00085.x","article-title":"Microbial responses to xenobiotic compounds. Identification of genes that allow <italic>Pseudomonas putida<\/italic> KT2440 to cope with 2,4,6-trinitrotoluene","volume":"2","author":"M Fern\u00e1ndez","year":"2009","journal-title":"Microb Biotechnol"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1111\/j.1574-6976.2010.00249.x","article-title":"Comparative genomics and functional analysis of niche-specific adaptation in <italic>Pseudomonas putida<\/italic>","volume":"35","author":"X Wu","year":"2011","journal-title":"FEMS Microbiol Rev"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"2278","DOI":"10.1021\/es102095t","article-title":"Chromium(VI) bioremoval by <italic>Pseudomonas<\/italic> bacteria: role of microbial exudates for natural attenuation and biotreatment of Cr(VI) contamination","volume":"45","author":"NM Dogan","year":"2011","journal-title":"Environ Sci Technol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"6789","DOI":"10.1128\/JB.06201-11","article-title":"Genome sequence of <italic>Pseudomonas putida<\/italic> strain B6-2, a superdegrader of polycyclic aromatic hydrocarbons and dioxin-like compounds","volume":"193","author":"H Tang","year":"2011","journal-title":"J Bacteriol"},{"key":"ref7","first-page":"265","article-title":"Pathogenic significance of <italic>Pseudomonas fluorescens<\/italic> and <italic>Pseudomonas putida<\/italic>","volume":"44","author":"A von Graevenitz","year":"1971","journal-title":"Yale J Biol Med"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1007\/s10156-010-0114-0","article-title":"<italic>Pseudomonas putida<\/italic> bacteremia in adult patients: five case reports and a review of the literature","volume":"17","author":"Y Yoshino","year":"2011","journal-title":"J Infect Chemother"},{"key":"ref9","first-page":"637","article-title":"<italic>Pseudomonas putida<\/italic>: identification, antibiotic sensitivity and pathogenicity","volume":"25","author":"ML Loiseau-Marolleau","year":"1977","journal-title":"Pathol Biol (Paris)"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"1522","DOI":"10.1128\/AAC.47.5.1522-1528.2003","article-title":"IMP-12, a new plasmid-encoded metallo-beta-lactamase from a <italic>Pseudomonas putida<\/italic> clinical isolate","volume":"47","author":"JD Docquier","year":"2003","journal-title":"Antimicrob Agents Chemother"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"4246","DOI":"10.1128\/JCM.41.9.4246-4251.2003","article-title":"Presence of <italic>Pseudomonas putida<\/italic> strains harboring plasmids bearing the metallo-beta-lactamase gene <italic>bla<\/italic>(IMP) in a hospital in Japan","volume":"41","author":"S Yomoda","year":"2003","journal-title":"J Clin Microbiol"},{"key":"ref12","first-page":"25","article-title":"The 2000 Garrod lecture. Factors impacting on the problem of antibiotic resistance","volume":"49","author":"SB Levy","year":"2002","journal-title":"J Antimicrob Chemother"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"2761","DOI":"10.1128\/JCM.01228-07","article-title":"16S rRNA gene sequencing for bacterial identification in the diagnostic laboratory: pluses, perils, and pitfalls","volume":"45","author":"JM Janda","year":"2007","journal-title":"J Clin Microbiol"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"1826","DOI":"10.1093\/nar\/30.8.1826","article-title":"Species-specific repetitive extragenic palindromic (REP) sequences in <italic>Pseudomonas putida<\/italic>","volume":"30","author":"I Aranda-Olmedo","year":"2002","journal-title":"Nucleic Acids Res"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/0378-1119(81)90080-9","article-title":"Specific-purpose plasmid cloning vectors. II. Broad host range, high copy number, RSF1010-derived vectors, and a host-vector system for gene cloning in <italic>Pseudomonas<\/italic>","volume":"16","author":"M Bagdasarian","year":"1981","journal-title":"Gene"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"1939","DOI":"10.1111\/j.1462-2920.2007.01310.x","article-title":"Multilocus sequence analysis of biocontrol fluorescent <italic>Pseudomonas<\/italic> spp. producing the antifungal compound 2,4-diacetylphloroglucinol","volume":"9","author":"M Frapolli","year":"2007","journal-title":"Environ Microbiol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"6194","DOI":"10.1128\/AEM.02322-07","article-title":"Multilocus sequence typing and phylogenetic analyses of <italic>Pseudomonas aeruginosa<\/italic> isolates from the ocean","volume":"74","author":"NH Khan","year":"2008","journal-title":"Appl Environ Microbiol"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1093\/jac\/48.suppl_1.5","article-title":"Determination of minimum inhibitory concentrations","volume":"48","author":"JM Andrews","year":"2001","journal-title":"J. Antimicrob Chemother"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/S0076-6879(01)37026-X","article-title":"The MBEC assay system; Multiple equivalent biofilms for antibiotic and biocide susceptibility testing","volume":"337","author":"H Ceri","year":"2001","journal-title":"Methods Enzymol"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1128\/JB.120.1.416-423.1974","article-title":"Metabolism of benzoate and the methylbenzoates by <italic>Pseudomonas putida<\/italic> (arvilla) mt-2: evidence for the existence of a TOL plasmid","volume":"120","author":"PA Williams","year":"1974","journal-title":"J Bacteriol"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"4636","DOI":"10.1093\/nar\/27.23.4636","article-title":"Improved microbial gene identification with GLIMMER","volume":"27","author":"AL Delcher","year":"1999","journal-title":"Nucleic Acids Res"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"3389","DOI":"10.1093\/nar\/25.17.3389","article-title":"Gapped BLAST and PSI-BLAST: a new generation of protein database search programs","volume":"25","author":"SF Altschul","year":"1997","journal-title":"Nucleic Acids Res"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"1556","DOI":"10.1099\/mic.0.2006\/005223-0","article-title":"Characterization of environmentally friendly nicotine degradation by <italic>Pseudomonas putida<\/italic> biotype A strain S16","volume":"153","author":"SN Wang","year":"2007","journal-title":"Microbiology"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"W465","DOI":"10.1093\/nar\/gkn180","article-title":"Phylogeny.fr: robust phylogenetic analysis for the non-specialist","volume":"36","author":"A Dereeper","year":"2008","journal-title":"Nucleic Acids Res"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1099\/00221287-148-2-341","article-title":"Root colonization by <italic>Pseudomonas putida<\/italic>; love at first sight","volume":"148","author":"M Espinosa-Urgel","year":"2002","journal-title":"Microbiology"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1128\/AAC.01252-10","article-title":"A two-component regulatory system interconnects resistance to polymyxins, aminoglycosides, fluoroquinolones, and \u03b2-lactams in <italic>Pseudomonas aeruginosa<\/italic>","volume":"55","author":"C Muller","year":"2011","journal-title":"Antimicrob Agents Chemother"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1093\/jac\/dki254","article-title":"Mechanisms of resistance to fluoroquinolones and carbapenems in <italic>Pseudomonas putida<\/italic>","volume":"56","author":"T Horii","year":"2005","journal-title":"J Antimicrob Chemother"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1099\/jmm.0.018036-0","article-title":"Nosocomial infection by VIM-2 metallo-beta-lactamase-producing <italic>Pseudomonas putida<\/italic>","volume":"59","author":"M Trevi\u00f1o","year":"2010","journal-title":"J Med Microbiol"},{"key":"ref29","first-page":"344","article-title":"Metallo beta-lactamase producing <italic>Pseudomonas<\/italic> species\u2013a major cause of concern among hospital associated urinary tract infection","volume":"108","author":"R Saha","year":"2010","journal-title":"J Indian Med Assoc"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"2611","DOI":"10.1128\/AAC.00838-06","article-title":"Characterization of an integron carrying blaIMP-1 and a new aminoglycoside resistance gene, aac(6\u2032)-31, and its dissemination among genetically unrelated clinical isolates in a Brazilian hospital","volume":"51","author":"RE Mendes","year":"2007","journal-title":"Antimicrob Agents Chemother"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1007\/s10156-008-0661-9","article-title":"Molecular characterizations of carbapenem and ciprofloxacin resistance in clinical isolates of <italic>Pseudomonas putida<\/italic>","volume":"15","author":"W Kumita","year":"2009","journal-title":"J Infect Chemother"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.diagmicrobio.2004.11.002","article-title":"Nonfermentative gram-negative bacilli in cancer patients: increasing frequency of infection and antimicrobial susceptibility of clinical isolates to fluoroquinolones","volume":"51","author":"KV Rolston","year":"2005","journal-title":"Diagn Microbiol Infect Dis"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1128\/AAC.44.4.891-897.2000","article-title":"Characterization of VIM-2, a carbapenem-hydrolyzing metallo-beta-lactamase and its plasmid- and integron-borne gene from a <italic>Pseudomonas aeruginosa<\/italic> clinical isolate in France","volume":"44","author":"L Poirel","year":"2000","journal-title":"Antimicrob Agents Chemother"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"985","DOI":"10.2165\/11315700-000000000-00000","article-title":"Chronic obstructive pulmonary disease: role of bacteria and updated guide to antibacterial selection in the older patient","volume":"26","author":"PG Iyer","year":"2009","journal-title":"Drugs Aging"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1128\/AAC.05829-11","article-title":"PmrB mutations promote polymyxin resistance of <italic>Pseudomonas aeruginosa<\/italic> isolated from colistin-treated cystic fibrosis patients","volume":"56","author":"SM Moskowitz","year":"2012","journal-title":"Antimicrob Agents Chemother"},{"key":"ref36","article-title":"Identication of reciprocal adhesi\u00f3n genes in pathogenic and nonpathogenic <italic>Pseudomnonas<\/italic>","author":"E Duque","year":"2012","journal-title":"Environ Microbiol and EMI R"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"1468","DOI":"10.1111\/j.1462-2920.2010.02166.x","article-title":"Identification of conditionally essential genes for growth of <italic>Pseudomonas putida<\/italic> KT2440 on minimal medium through the screening of a genome-wide mutant library","volume":"12","author":"MA Molina-Henares","year":"2010","journal-title":"Environ Microbiol"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/s00253-005-0119-2","article-title":"Genetic organization of a plasmid from an industrial wastewater bioreactor","volume":"71","author":"M Bramucci","year":"2006","journal-title":"Appl Microbiol Biotechnol"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.micres.2005.02.004","article-title":"Overexpression, purification and characterization of a new salicylate hydroxylase from naphthalene-degrading <italic>Pseudomonas<\/italic> sp. strain ND6","volume":"160","author":"H Zhao","year":"2005","journal-title":"Microbiol Res"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"e27297","DOI":"10.1371\/journal.pone.0027297","article-title":"<italic>Pseudomonas syringae<\/italic> pv. <italic>actinidiae<\/italic> draft genomes comparison reveal strain-specific features involved in adaptation and virulence to <italic>Actinidia<\/italic> species","volume":"6","author":"S Marcelletti","year":"2011","journal-title":"PLoS One"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"1740","DOI":"10.1021\/es0306258","article-title":"Effect of root-derived substrates on the expression of <italic>nah-lux<\/italic> genes in <italic>Pseudomonas fluorescens<\/italic> HK44: implications for PAH biodegradation in the rhizosphere","volume":"38","author":"R Kamath","year":"2004","journal-title":"Environ Sci Technol"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"22","DOI":"10.3389\/fmicb.2011.00022","article-title":"Quinolone Resistance: Much More than Predicted","volume":"2","author":"A Hern\u00e1ndez","year":"2011","journal-title":"Front Microbiol"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"4012","DOI":"10.1128\/AAC.48.10.4012-4015.2004","article-title":"Prevalence of mutations within the quinolone resistance-determining region of <italic>gyrA, gyrB, parC<\/italic>, and <italic>parE<\/italic> and association with antibiotic resistance in quinolone-resistant <italic>Salmonella enterica<\/italic>","volume":"48","author":"DJ Eaves","year":"2004","journal-title":"Antimicrob Agents Chemother"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1046\/j.1365-2958.2003.03673.x","article-title":"Cationic antimicrobial peptides activate a two component regulatory system, PmrA-PmrB, that regulates resistance to polymyxin B and cationic antimicrobial peptides in <italic>Pseudomonas aeruginosa<\/italic>","volume":"50","author":"JB McPhee","year":"2003","journal-title":"Mol Microbiol"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"2515","DOI":"10.1099\/mic.0.050088-0","article-title":"The PmrA\/PmrB regulatory system controls the expression of the <italic>wzzfepE<\/italic> gene involved in the O-antigen synthesis of <italic>Salmonella enterica<\/italic> serovar Typhimurium","volume":"157","author":"ML Pescaretti","year":"2011","journal-title":"Microbiology"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1128\/AAC.37.2.354","article-title":"Outer membrane permeability barrier to azithromycin, clarithromycin, and roxithromycin in gram-negative enteric bacteria","volume":"37","author":"M Vaara","year":"1993","journal-title":"Antimicrob Agents Chemother"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"e29276","DOI":"10.1371\/journal.pone.0029276","article-title":"Phenotypic and genome-wide analysis of an antibiotic-resistant small colony variant (SCV) of <italic>Pseudomonas aeruginosa<\/italic>","volume":"6","author":"Q Wei","year":"2011","journal-title":"PLoS One"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"2506","DOI":"10.1128\/AAC.01640-05","article-title":"Reverse engineering antibiotic sensitivity in a multidrug-resistant <italic>Pseudomonas aeruginosa<\/italic> isolate","volume":"50","author":"JM Struble","year":"2006","journal-title":"Antimicrob Agents Chemother"},{"key":"ref49","first-page":"1519","article-title":"The prevalence of aminoglycoside-modifying enzyme genes (aac (6\u2032)-I, aac (6\u2032)-II, ant (2\u2033)-I, aph (3\u2032)-VI) in <italic>Pseudomonas aeruginosa<\/italic>","volume":"66","author":"F Vaziri","year":"2011","journal-title":"Clinics (Sao Paulo)"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1111\/j.1365-2958.1988.tb00081.x","article-title":"Nucleotide sequence analysis of 2\u2033-aminoglycoside nucleotidyl-transferase ANT(2\u2033) from Tn<italic>4000<\/italic>: its relationship with AAD(3\u2033) and impact on Tn21 evolution","volume":"2","author":"FR Schmidt","year":"1988","journal-title":"Mol Microbiol"},{"key":"ref51","first-page":"365","article-title":"Occurrence of the <italic>strA-strB<\/italic> streptomycin resistance genes in <italic>Pseudomonas<\/italic> species isolated from kiwifruit plants","volume":"42","author":"HS Han","year":"2004","journal-title":"J Microbiol"},{"key":"ref52","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1128\/AAC.01034-06","article-title":"Overexpression and initial characterization of the chromosomal aminoglycoside 3\u2032-O-phosphotransferase APH(3\u2032)-IIb from <italic>Pseudomonas aeruginosa<\/italic>","volume":"51","author":"M Hainrichson","year":"2007","journal-title":"Antimicrob Agents Chemother"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/s11259-010-9448-4","article-title":"Re-emergence of multi-drug resistant <italic>Salmonella enterica<\/italic> serovar Stanley from cattle","volume":"35","author":"H Dahshan","year":"2011","journal-title":"Vet Res Commun"},{"key":"ref54","doi-asserted-by":"crossref","first-page":"1558","DOI":"10.1111\/j.1469-0691.2010.03165.x","article-title":"Tn<italic>5090<\/italic>-like class 1 integron carrying <italic>bla<\/italic>(VIM-2) in a <italic>Pseudomonas putida<\/italic> strain from Portugal","volume":"16","author":"C Santos","year":"2010","journal-title":"Clin Microbiol Infect"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1021\/bi00271a020","article-title":"Photoincorporation of tetracycline into <italic>Escherichia coli<\/italic> ribosomes. Identification of the major proteins photolabeled by native tetracycline and tetracycline photoproducts and implications for the inhibitory action of tetracycline on protein synthesis","volume":"22","author":"RA Goldman","year":"1983","journal-title":"Biochemistry"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"65S","DOI":"10.1046\/j.1365-2672.92.5s1.4.x","article-title":"Levy SB (2002 b) Active efflux, a common mechanism for biocide and antibiotic resistance","volume":"92","journal-title":"J Appl Microbiol"},{"key":"ref57","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1111\/j.1751-7915.2010.00189.x","article-title":"Characterization of the RND family of multidrug efflux pumps: <italic>in silico<\/italic> to <italic>in vivo<\/italic> confirmation of four functionally distinct subgroups","volume":"3","author":"P Godoy","year":"2010","journal-title":"Microb Biotech"},{"key":"ref58","doi-asserted-by":"crossref","first-page":"3967","DOI":"10.1128\/JB.183.13.3967-3973.2001","article-title":"Three efflux pumps are required to provide efficient tolerance to toluene in <italic>Pseudomonas putida<\/italic> DOT-T1E","volume":"183","author":"A Rojas","year":"2001","journal-title":"J Bacteriol"},{"key":"ref59","doi-asserted-by":"crossref","first-page":"1550","DOI":"10.1111\/j.1462-2920.2007.01276.x","article-title":"The <italic>ttgGHI<\/italic> solvent efflux pump operon of <italic>Pseudomonas putida<\/italic> DOT-T1E is located on a large self-transmissible plasmid","volume":"9","author":"JJ Rodr\u00edguez-Herva","year":"2007","journal-title":"Environ Microbiol"},{"key":"ref60","doi-asserted-by":"crossref","first-page":"2315","DOI":"10.1111\/j.1462-2920.2011.02492.x","article-title":"The pGRT1 plasmid of <italic>Pseudomonas putida<\/italic> DOT-T1E encodes functions relevant for survival under harsh conditions in the environment","volume":"13","author":"L Molina","year":"2011","journal-title":"Environ Microbiol"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"3974","DOI":"10.1073\/pnas.77.7.3974","article-title":"Active efflux of tetracycline encoded by four genetically different tetracycline resistance determinants in <italic>Escherichia coli<\/italic>","volume":"77","author":"LM McMurry","year":"1980","journal-title":"Proc Natl Acad Sci (USA)"},{"key":"ref62","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1128\/CMR.8.4.557","article-title":"beta-Lactamases in laboratory and clinical resistance","volume":"8","author":"DM Livermore","year":"1995","journal-title":"Clin Microbiol Rev"},{"key":"ref63","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1128\/AAC.27.4.479","article-title":"Genetic and biochemical properties of AER-1, a novel carbenicillin-hydrolyzing beta-lactamase from <italic>Aeromonas hydrophila<\/italic>","volume":"27","author":"RW Hedges","year":"1985","journal-title":"Antimicrob Agents Chemother 1985"},{"key":"ref64","first-page":"19944","article-title":"Outbreak due to a <italic>Klebsiella pneumoniae<\/italic> strain harbouring KPC-2 and VIM-1 in a German university hospital, July 2010 to January","volume":"16 pii","author":"J Steinmann","year":"2011","journal-title":"Euro Surveill"},{"key":"ref65","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1128\/AAC.05398-11","article-title":"Mechanisms of resistance to chloramphenicol <italic>in Pseudomonas putida<\/italic> KT2440","volume":"56","author":"M Fern\u00e1ndez","year":"2012","journal-title":"Antimicrob Agents Chemother"},{"key":"ref66","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1093\/oxfordjournals.jbchem.a022078","article-title":"Evidence for chloramphenicol\/H<sup>+<\/sup> antiport in Cmr (MdfA) system of <italic>Escherichia coli<\/italic> and properties of the antiporter","volume":"124","author":"Tl Minek","year":"1998","journal-title":"J Biochem"},{"key":"ref67","unstructured":"Kent M (2000) Advanced Biology, Oxford University Press, p. 46 ISBN 9780199141951."},{"key":"ref68","doi-asserted-by":"crossref","first-page":"1684","DOI":"10.1128\/AAC.32.11.1684","article-title":"RSF1010 and a conjugative plasmid contain <italic>sul<\/italic>II, one of two known genes for plasmid-borne sulfonamide resistance dihydropteroate synthase","volume":"32","author":"P R\u00e5dstr\u00f6m","year":"1988","journal-title":"Antimicrob Agents Chemother"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0081604","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,23]],"date-time":"2024-05-23T09:14:54Z","timestamp":1716455694000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0081604"}},"subtitle":[],"editor":[{"given":"Jacob Guy","family":"Bundy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2014,1,17]]},"references-count":68,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2014,1,17]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0081604","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,1,17]]}}}